Molecular mimic between cardiovascular diseases and microorganism antigens

CONCLUSION: Human actin and HSPs share a high degree of conservation with epitopes from various microorganisms, such as bacteria, fungi and protozoa, suggesting molecular mimicry and cross-reactivity as a mechanism for the development of atherosclerosis, heart disease rheumatic disease, myocarditis and Chagas heart disease. In vitro and in vivo work is needed to demonstrate the results obtained in the In Silico analysis.PMID:38683079 | DOI:10.29262/ram.v71i1.1379

Source: Atherosclerosis - April 29, 2024 Category: Cardiology Authors: Andr és Sánchez-Caraballo Valentina Garc ía-Solano Sonia Karina Gonz ález-Rangel Valeria Grattz-Lamadrid Marlon Munera-Gomez Source Type: research