Clinical effectiveness of pit and fissure sealants in primary and permanent teeth of children and adolescents: an umbrella review
ConclusionConsidering the limitations of this umbrella review, sealants are more effective for caries prevention in children ’s permanent molars compared to no treatment. Future well-implemented RCTs are needed to draw reliable conclusions on the clinical effectiveness of sealants in primary and permanent teeth of children and adolescents. (Source: European Archives of Paediatric Dentistry)
Source: European Archives of Paediatric Dentistry - March 15, 2024 Category: Dentistry Source Type: research
ImmunoPET/CT imaging of clear cell renal cell carcinoma with [ < sup > 18 < /sup > F]RCCB6: a first-in-human study
CONCLUSION: The work successfully developed a series of CD70-targeted immunoPET/CT imaging tracers. Of them, [18F]RCCB6 clearly and specifically identified inoculated ccRCCs in preclinical studies. Clinical translation of [18F]RCCB6 suggests potential for identifying recurrence and/or metastasis in ccRCC patients.PMID:38480552 | DOI:10.1007/s00259-024-06672-3 (Source: Molecular Medicine)
Source: Molecular Medicine - March 14, 2024 Category: Molecular Biology Authors: Qianyun Wu Yanfei Wu You Zhang Yihui Guan Gang Huang Fang Xie Jianjun Liu Wei Zhai Weijun Wei Source Type: research
An Ultralow-concentration and Moisture-resistant Electrolyte of Lithium Difluoro(oxalato)borate in Carbonate Solvents for Stable Cycling in Practical Lithium-ion Batteries
Angew Chem Int Ed Engl. 2024 Mar 14:e202400110. doi: 10.1002/anie.202400110. Online ahead of print.ABSTRACTThe electrolyte concentration not only impacts the battery performance but also affects the battery cost and manufacturing. Currently, most studies focus on high-concentration (>3 M) or localized high-concentration electrolytes (~1 M); however, the expensive lithium salt imposes a major concern. Most recently, ultralow concentration electrolytes (<0.3 M) have emerged as intriguing alternatives for battery applications, which feature low cost, low viscosity, and extreme-temperature operation. However, at such an ...
Source: Angewandte Chemie - March 14, 2024 Category: Chemistry Authors: Zhishan Liu Wentao Hou Haoran Tian Qian Qiu Irfan Ullah Shen Qiu Wei Sun Qian Yu Jinliang Yuan Lan Xia Xianyong Wu Source Type: research
Fluorescent responsive membrane based on terbium coordination polymer and carbon dots with AIE effect for rapid and visual detection of fluoroquinolone
In this study, based on aggregation-induced emission (AIE) effect and antenna effect, a novel portable fluorescent responsive membrane was constructed with red carbon dots (R-CDs) as reference signal and terbium coordination polymer (Tb-AMP CPs) as response signal for visual, instrument-free, and sensitive detection of fluoroquinolones (FQs). Specifically, the fluorescent responsive membrane (R-T membrane) was prepared by physically depositing R-CDs with AIE property and Tb-AMP CPs on the surface of polyvinylidene fluoride filter membranes at ambient temperature. In the presence of FQs, Tb3+ in the Tb-AMP CPs of the prepar...
Source: Biosensors and Bioelectronics - March 14, 2024 Category: Biotechnology Authors: Yunyun Hu Xi Chen Kai Wang Chuang Jiang Wenya Liu Siyu Zhang Mingming Zheng Yibin Zhou Yaqing Xiao Yingnan Liu Source Type: research
ImmunoPET/CT imaging of clear cell renal cell carcinoma with [ < sup > 18 < /sup > F]RCCB6: a first-in-human study
CONCLUSION: The work successfully developed a series of CD70-targeted immunoPET/CT imaging tracers. Of them, [18F]RCCB6 clearly and specifically identified inoculated ccRCCs in preclinical studies. Clinical translation of [18F]RCCB6 suggests potential for identifying recurrence and/or metastasis in ccRCC patients.PMID:38480552 | DOI:10.1007/s00259-024-06672-3 (Source: Molecular Medicine)
Source: Molecular Medicine - March 14, 2024 Category: Molecular Biology Authors: Qianyun Wu Yanfei Wu You Zhang Yihui Guan Gang Huang Fang Xie Jianjun Liu Wei Zhai Weijun Wei Source Type: research
Fluorescent responsive membrane based on terbium coordination polymer and carbon dots with AIE effect for rapid and visual detection of fluoroquinolone
In this study, based on aggregation-induced emission (AIE) effect and antenna effect, a novel portable fluorescent responsive membrane was constructed with red carbon dots (R-CDs) as reference signal and terbium coordination polymer (Tb-AMP CPs) as response signal for visual, instrument-free, and sensitive detection of fluoroquinolones (FQs). Specifically, the fluorescent responsive membrane (R-T membrane) was prepared by physically depositing R-CDs with AIE property and Tb-AMP CPs on the surface of polyvinylidene fluoride filter membranes at ambient temperature. In the presence of FQs, Tb3+ in the Tb-AMP CPs of the prepar...
Source: Biosensors and Bioelectronics - March 14, 2024 Category: Biotechnology Authors: Yunyun Hu Xi Chen Kai Wang Chuang Jiang Wenya Liu Siyu Zhang Mingming Zheng Yibin Zhou Yaqing Xiao Yingnan Liu Source Type: research
Sensors, Vol. 24, Pages 1859: Flexible 3D Force Sensor Based on Polymer Nanocomposite for Soft Robotics and Medical Applications
i
The three-dimensional (3D) force sensor has become essential in industrial and medical applications. The existing conventional 3D force sensors quantify the three-direction force components at a point of interest or extended contact area. However, they are typically made of rigid, complex structures and expensive materials, making them hard to implement in different soft or fixable industrial and medical applications. In this work, a new flexible 3D force sensor based on polymer nanocomposite (PNC) sensing elements was proposed and tested for its sensitivity to forces in the 3D space. Multi-walled carbon nanotube/pol...
Source: Sensors - March 14, 2024 Category: Biotechnology Authors: Ahmed Alotaibi Tags: Article Source Type: research
Molecules, Vol. 29, Pages 1284: Selective CO2 Capture from CO2/N2 Gas Mixtures Utilizing Tetrabutylammonium Fluoride Hydrates
This study provides sufficient data to support the feasibility of TBAF hydrate systems to be applied to CO2 separation from CO2/N2 gas mixtures based on their CO2 selectivity. (Source: Molecules)
Source: Molecules - March 14, 2024 Category: Chemistry Authors: Hyeonjin Kim Yun-Ho Ahn Tags: Article Source Type: research
ImmunoPET/CT imaging of clear cell renal cell carcinoma with [18F]RCCB6: a first-in-human study
ConclusionThe work successfully developed a series of CD70-targeted immunoPET/CT imaging tracers. Of them, [18F]RCCB6 clearly and specifically identified inoculated ccRCCs in preclinical studies. Clinical translation of [18F]RCCB6 suggests potential for identifying recurrence and/or metastasis in ccRCC patients. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - March 14, 2024 Category: Nuclear Medicine Source Type: research
How to Deal with Charge in the Ranking of Lewis Acidity: Critical Evaluation of an Extensive Set of Cationic Lewis Acids
Angew Chem Int Ed Engl. 2024 Mar 13:e202403356. doi: 10.1002/anie.202403356. Online ahead of print.ABSTRACTThe quantification of Lewis acidity is of fundamental and applied importance in chemistry. However, if neutral and charged Lewis acids are compared, a coherent ranking has been elusive, and severe uncertainties were accepted. With this study, we present a systematic computational analysis of Lewis base affinities of 784 mono-, di- and tricationic Lewis acids and their comparison with 149 representative neutral Lewis acids. Evaluating vacuum fluoride ion affinities (FIA) reveals a charge-caused clustering that prohibit...
Source: Angewandte Chemie - March 13, 2024 Category: Chemistry Authors: Philipp Erdmann Manuel Schmitt Lukas M Sigmund Felix Kr ämer Frank Breher Lutz Greb Source Type: research
Rutin mitigates fluoride-induced nephrotoxicity by inhibiting ROS-mediated lysosomal membrane permeabilization and the GSDME-HMGB1 axis involved in pyroptosis and inflammation
In conclusion, our findings suggest that NaF induces renal damage through ROS-mediated activation of LMP and the GSDME/HMGB1 axis, leading to pyroptosis and inflammation. Rutin, a natural antioxidative and anti-inflammatory dietary supplement, offers a novel approach to prevent and treat fluoride-induced nephrotoxicity.PMID:38479315 | DOI:10.1016/j.ecoenv.2024.116195 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 13, 2024 Category: Environmental Health Authors: Yue Ma Panpan Xu Hengrui Xing Yue Zhang Tingting Li Xueman Ding Li Liu Qiang Niu Source Type: research
Toward the development of a molecular toolkit for the microbial remediation of per-and polyfluoroalkyl substances
Appl Environ Microbiol. 2024 Mar 13:e0015724. doi: 10.1128/aem.00157-24. Online ahead of print.ABSTRACTPer- and polyfluoroalkyl substances (PFAS) are highly fluorinated synthetic organic compounds that have been used extensively in various industries owing to their unique properties. The PFAS family encompasses diverse classes, with only a fraction being commercially relevant. These substances are found in the environment, including in water sources, soil, and wildlife, leading to human exposure and fueling concerns about potential human health impacts. Although PFAS degradation is challenging, biodegradation offers a prom...
Source: Applied and Environmental Microbiology - March 13, 2024 Category: Microbiology Authors: Miao Hu Colin Scott Source Type: research
Role of (18)F-sodium fluoride positron emission tomography in imaging atherosclerosis
J Nucl Cardiol. 2024 Mar 11:101845. doi: 10.1016/j.nuclcard.2024.101845. Online ahead of print.ABSTRACTAtherosclerosis involving vascular beds across the human body remains the leading cause of death worldwide. Coronary and peripheral artery disease which are almost universally a result of atherosclerotic plaque can manifest clinically as myocardial infarctions, ischemic stroke or acute lower limb ischemia. Beyond imaging myocardial perfusion and blood flow nuclear imaging has the potential to depict the activity of the processes which are directly implicated in the atherosclerotic plaque progression and rupture. Out of se...
Source: Atherosclerosis - March 13, 2024 Category: Cardiology Authors: Jacek Kwiecinski Source Type: research
Rosuvastatin effect on atherosclerotic plaque metabolism: A subclinical atherosclerosis imaging study with (18)F-NaF PET-CT
CONCLUSION: In a single-centre non-randomized clinical trial of high CV risk individuals with subclinical atherosclerosis, the maximum atherosclerotic plaque 18F-NaF uptake was significantly reduced after six months of high-intensity statin.PMID:38480058 | DOI:10.1016/j.atherosclerosis.2024.117481 (Source: Atherosclerosis)
Source: Atherosclerosis - March 13, 2024 Category: Cardiology Authors: Manuel Oliveira-Santos Jo ão Borges-Rosa Rodolfo Silva Lu ís Paixão Cl áudio Espírito Santo Antero Abrunhosa Miguel Castelo-Branco Piotr J Slomka Lino Gon çalves Maria Jo ão Ferreira Source Type: research
Rutin mitigates fluoride-induced nephrotoxicity by inhibiting ROS-mediated lysosomal membrane permeabilization and the GSDME-HMGB1 axis involved in pyroptosis and inflammation
In conclusion, our findings suggest that NaF induces renal damage through ROS-mediated activation of LMP and the GSDME/HMGB1 axis, leading to pyroptosis and inflammation. Rutin, a natural antioxidative and anti-inflammatory dietary supplement, offers a novel approach to prevent and treat fluoride-induced nephrotoxicity.PMID:38479315 | DOI:10.1016/j.ecoenv.2024.116195 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 13, 2024 Category: Environmental Health Authors: Yue Ma Panpan Xu Hengrui Xing Yue Zhang Tingting Li Xueman Ding Li Liu Qiang Niu Source Type: research
