Deoxyfluorinated amidation and esterification of carboxylic acid by pyridinesulfonyl fluoride
We report an amide bond formation reaction through deoxyfluorinated carboxylic acids under mild conditions using 2-pyridinesulfonyl fluoride. The reaction procedure has been used in a one-pot synthesis of amides and esters via in situ generation of acyl fluoride. This one-pot synthetic method provides easy access to amides and esters. Using this method, we have sequentially synthesized a tetrapeptide and calceolarioside-B glycoside derivative with good yields.PMID:38602165 | DOI:10.1039/d4cc00877d (Source: Chemical Communications)
Source: Chemical Communications - April 11, 2024 Category: Chemistry Authors: Anootha Neeliveettil Soumyadip Dey Vishnu Nomula Swati Thakur Debabrata Giri Abhishek Santra Abhijit Sau Source Type: research
Synthetic strategy for the production of electrically polarized polyvinylidene fluoride-trifluoroethylene-co-polymer osseo-functionalized with hydroxyapatite scaffold
J Biomed Mater Res A. 2024 Apr 10. doi: 10.1002/jbm.a.37720. Online ahead of print.ABSTRACTThe physiological mechanism of bone tissue regeneration is intricately organized and involves several cell types, intracellular, and extracellular molecular signaling networks. To overcome the drawbacks of autografts and allografts, a number of synthetically produced scaffolds have been manufactured by integrating ceramics, polymers, and their hybrid-composites. Considering the fact that natural bone is composed primarily of collagen and hydroxyapatite, ceramic-polymer composite materials seem to be the most viable alternative to bon...
Source: Biomed Res - April 11, 2024 Category: Research Authors: Subhasmita Swain Rojaleen Lenka Tapash Rautray Source Type: research
Stratified control of chemical crystallization in a pellet fluidized bed for pH-Adjusted fluoride and phosphate reduction: An experimental study
This study investigates the impact of stratified pH control in a crystallization granulation fluidized bed for the removal of fluoride and phosphate on a pilot scale. The results indicate that using dolomite as a seed crystal, employing sodium dihydrogen phosphate (SDP) and calcium chloride as crystallizing agents, and controlling the molar ratio n(F):n(P):n(Ca) = 1:5:10 with an upflow velocity of 7.52 m/h, effectively removes fluoride and phosphate. Stratified pH control-maintaining weakly acidic conditions (pH = 6-7) at the bottom and weakly alkaline conditions (pH = 7-8) at the top-facilitates the induction of fluoroapa...
Source: Environmental Research - April 11, 2024 Category: Environmental Health Authors: Ruizhu Hu Shichang Li Kaihong Li Tinglin Huang Zenan Liu Gang Wen Source Type: research
Deoxyfluorinated amidation and esterification of carboxylic acid by pyridinesulfonyl fluoride
We report an amide bond formation reaction through deoxyfluorinated carboxylic acids under mild conditions using 2-pyridinesulfonyl fluoride. The reaction procedure has been used in a one-pot synthesis of amides and esters via in situ generation of acyl fluoride. This one-pot synthetic method provides easy access to amides and esters. Using this method, we have sequentially synthesized a tetrapeptide and calceolarioside-B glycoside derivative with good yields.PMID:38602165 | DOI:10.1039/d4cc00877d (Source: Chemical Communications)
Source: Chemical Communications - April 11, 2024 Category: Chemistry Authors: Anootha Neeliveettil Soumyadip Dey Vishnu Nomula Swati Thakur Debabrata Giri Abhishek Santra Abhijit Sau Source Type: research
Stratified control of chemical crystallization in a pellet fluidized bed for pH-Adjusted fluoride and phosphate reduction: An experimental study
This study investigates the impact of stratified pH control in a crystallization granulation fluidized bed for the removal of fluoride and phosphate on a pilot scale. The results indicate that using dolomite as a seed crystal, employing sodium dihydrogen phosphate (SDP) and calcium chloride as crystallizing agents, and controlling the molar ratio n(F):n(P):n(Ca) = 1:5:10 with an upflow velocity of 7.52 m/h, effectively removes fluoride and phosphate. Stratified pH control-maintaining weakly acidic conditions (pH = 6-7) at the bottom and weakly alkaline conditions (pH = 7-8) at the top-facilitates the induction of fluoroapa...
Source: Environmental Research - April 11, 2024 Category: Environmental Health Authors: Ruizhu Hu Shichang Li Kaihong Li Tinglin Huang Zenan Liu Gang Wen Source Type: research
High-accuracy experimental determination of photon mass attenuation coefficients of transition metals and lithium fluoride in the ultra-soft energy range
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Pia Schweizer, Yves M énesguen, Marie-Christine Lépy, Emmanuelle Brackx, Maxime Duchateau, Philippe Jonnard Precise knowledge of photon mass attenuation coefficients for elemental quantification in X-ray analysis is crucial. The transmittance measurements reveal significant differences from existing data tables, particularly around absorption edges. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Phys. Chem...
Source: RSC - Phys. Chem. Chem. Phys. latest articles - April 10, 2024 Category: Chemistry Authors: Pia Schweizer Source Type: research
Photoreduction of Trifluoromethyl Group: Lithium Ion Assisted Fluoride-Coupled Electron Transfer from EDA Complex
Chemistry. 2024 Apr 10:e202400658. doi: 10.1002/chem.202400658. Online ahead of print.ABSTRACTPhotoinduced single-electron reduction is an efficient method for the mono-selective activation of the C-F bond on a trifluoromethyl group to construct a difluoroalkyl group. We have developed an electron-donor-acceptor (EDA) complex mediated single-electron transfer (EDA-SET) of α,α,α-trifluoromethyl arenes in the presence of lithium salt to give α,α-difluoroalkylarenes. The C-F bond reduction was realized by lithium iodide and triethylamine, two common feedstock reagents. Mechanistic studies revealed the generation of a α,...
Source: Chemistry - April 10, 2024 Category: Chemistry Authors: Tatsuhiro Uchikura Fua Akutsu Haruna Tani Takahiko Akiyama Source Type: research
Plasma Glucose Concentrations in Different Sampling Tubes Measured on
Different Glucose Analysers
Conclusions The results confirm that glycolysis can be effectively
inhibited in citrate/fluoride-containing sampling tubes. However, glucose
measurement results of one analyser showed a relevant negative bias in tubes
containing liquid citrate buffer. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - April 10, 2024 Category: Endocrinology Authors: Pleus, Stefan Beil, Alexandra Baumstark, Annette Haug, Cornelia Freckmann, Guido Tags: Article Source Type: research
Disentangling the formation, mechanism, and evolvement of the covalent methanesulfonyl fluoride acetylcholinesterase adduct: Insights into an aged ‐like inactive complex susceptible to reactivation by a combination of nucleophiles
AbstractChemical warfare nerve agents and pesticides, known as organophosphorus compounds inactivate cholinesterases (ChEs) by phosphorylating the serine hydroxyl group located at the active site of ChEs. Over the course of time, phosphorylation is followed by loss of an organophosphate-leaving group and the bond with ChEs becomes irreversible, a process known as aging. Differently, structurally related irreversible catalytic poisons bearing sulfur instead of phosphorus convert ChEs in its aged form only by covalently binding to the key catalytic serine. Kinetic and crystallographic studies of the interaction betweenTorped...
Source: Protein Science - April 9, 2024 Category: Biochemistry Authors: Jure Stojan,
Alessandro Pesaresi,
An že Meden,
Doriano Lamba Tags: RESEARCH ARTICLE Source Type: research
Fluorosulfide La2.7Ba6.3F8.7S6 with Double-Layer Honeycomb Structure Enabling Fluoride-Ion Conduction
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Shintaro Tachibana, Chengchao Zhong, Takeshi Tojigamori, HIDENORI MIKI, Toshiyuki Matsunaga, Yuki Orikasa Mixed-anion compounds comprise anion-ordered layered structures with fluoride ionic conducting layers, which are not found in conventional metal fluorides. Hence, they represent a new frontier in the search for fluoride-ion... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - J. Mater. Chem. latest articles)
Source: RSC - J. Mater. Chem. latest articles - April 9, 2024 Category: Chemistry Authors: Shintaro Tachibana Source Type: research
Rational and controllable syntheses of variants of modified N-confused N-fused porphodimethenes and a porphotrimethene with adaptive properties
Dalton Trans., 2024, Advance Article DOI: 10.1039/D4DT00770K, PaperManik Jana, Sumit Sahoo, Sanjay Kottekad, Dandamudi Usharani, Harapriya Rath Striking compromise between flexibility and rigidity via built-in fused tetra pentacyclic moiety (5.5.5.5): Highly stable meso-aryl substituted core modified N-confused N-fused calix[4]phyrin analogues as selective fluoride ion receptorsvia deprotonation and/or anion recognition mechanism. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Dalton Trans. latest articles)
Source: RSC - Dalton Trans. latest articles - April 9, 2024 Category: Chemistry Authors: Manik Jana Source Type: research
Is there any association between fluoride exposure and thyroid function modulation? A systematic review
by Maria Karolina Martins Ferreira, Priscila Cunha Nascimento, Leonardo Oliveira Bittencourt, Giza Hellen Nonato Miranda, Nathalia Carolina Fernandes Fagundes, Fatemeh Vida Zahoori, E. Angeles Martinez-Mier, Mar ília Afonso Rabelo Buzalaf, Rafael Rodrigues Lima
Numerous pre-clinical and observational studies have explored the potential effects of fluoride (F) at varying concentrations on diverse systems and organs. While some have assessed the endocrinological conditions of children and adults, a consensus regarding the interaction between F and the thyr oid remains elusive. This systematic review aimed to gather primary...
Source: PLoS One - April 9, 2024 Category: Biomedical Science Authors: Maria Karolina Martins Ferreira Source Type: research
Anion-Responsive Colorimetric and Fluorometric Red-Shift in Triarylborane Derivatives: Dual Role of Phenazaborine as Lewis Acid and Electron Donor
Angew Chem Int Ed Engl. 2024 Apr 8:e202405158. doi: 10.1002/anie.202405158. Online ahead of print.ABSTRACTPhotophysical modulation of triarylboranes (TABs) through Lewis acid-base interactions is a fundamental approach in sensing anions. Yet, design principles for anion-responsive TABs displaying significant red-shift in absorption and photoluminescence (PL) have remained elusive. Herein, a new strategy for modulating photophysical properties of TABs in red-shift mode has been presented, endowing a nitrogen-bridged triarylborane (1,4-phenazaborine: PAzB) with a contradictory dual role as a Lewis acid and an electron donor....
Source: Angewandte Chemie - April 8, 2024 Category: Chemistry Authors: Nae Aota Riku Nakagawa Leonardo Evaristo de Sousa Norimitsu Tohnai Satoshi Minakata Piotr de Silva Youhei Takeda Source Type: research
Assessing groundwater quality dynamics in madhya pradesh: chemical contaminants and their temporal patterns
This study primarily aims to investigate the spatio-temporal variations in groundwater quality and evaluate its suitability for potable purposes in the region of Madhya Pradesh. The study combines the Mann-Kendall (MK) test and Sen's Slope (SS) to analyze the changes in groundwater quality of all 51 districts of Madhya Pradesh, India, utilizing 12 water quality indices using MATLAB. Data was sourced from the Central Ground Water Board (CGWB) in India from the year 2001 to 2021. The data was then tested for homogeneity at all 1154 sampling stations using the software XLSTAT. Piper plot clustering characterized the state's g...
Source: Environmental Research - April 8, 2024 Category: Environmental Health Authors: Satyam Mishra Mrityunjay Singh Chauhan Suresh Sundaramurthy Source Type: research
Anion-Responsive Colorimetric and Fluorometric Red-Shift in Triarylborane Derivatives: Dual Role of Phenazaborine as Lewis Acid and Electron Donor
Angew Chem Int Ed Engl. 2024 Apr 8:e202405158. doi: 10.1002/anie.202405158. Online ahead of print.ABSTRACTPhotophysical modulation of triarylboranes (TABs) through Lewis acid-base interactions is a fundamental approach in sensing anions. Yet, design principles for anion-responsive TABs displaying significant red-shift in absorption and photoluminescence (PL) have remained elusive. Herein, a new strategy for modulating photophysical properties of TABs in red-shift mode has been presented, endowing a nitrogen-bridged triarylborane (1,4-phenazaborine: PAzB) with a contradictory dual role as a Lewis acid and an electron donor....
Source: Angewandte Chemie - April 8, 2024 Category: Chemistry Authors: Nae Aota Riku Nakagawa Leonardo Evaristo de Sousa Norimitsu Tohnai Satoshi Minakata Piotr de Silva Youhei Takeda Source Type: research
