Establishment and validation of an adherence prediction system for lifestyle interventions in non-alcoholic fatty liver disease
CONCLUSION: The EDAS can reliably assess the adherence of patients with NAFLD to lifestyle interventions and have clinical application in this population.PMID:38596499 | PMC:PMC11000086 | DOI:10.3748/wjg.v30.i10.1393 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Ming-Hui Zeng Qi-Yu Shi Liang Xu Yu-Qiang Mi Source Type: research

Cumulative effects of excess high-normal alanine aminotransferase levels in relation to new-onset metabolic dysfunction-associated fatty liver disease in China
CONCLUSION: Most participants with MAFLD had normal ALT levels. Long-term high-normal ALT levels were associated with a cumulative increased risk of new-onset MAFLD.PMID:38596503 | PMC:PMC11000085 | DOI:10.3748/wjg.v30.i10.1346 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: Jing-Feng Chen Zhuo-Qing Wu Hao-Shuang Liu Su Yan You-Xiang Wang Miao Xing Xiao-Qin Song Su-Ying Ding Source Type: research

Establishment and validation of an adherence prediction system for lifestyle interventions in non-alcoholic fatty liver disease
CONCLUSION: The EDAS can reliably assess the adherence of patients with NAFLD to lifestyle interventions and have clinical application in this population.PMID:38596499 | PMC:PMC11000086 | DOI:10.3748/wjg.v30.i10.1393 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: Ming-Hui Zeng Qi-Yu Shi Liang Xu Yu-Qiang Mi Source Type: research

Cumulative effects of excess high-normal alanine aminotransferase levels in relation to new-onset metabolic dysfunction-associated fatty liver disease in China
CONCLUSION: Most participants with MAFLD had normal ALT levels. Long-term high-normal ALT levels were associated with a cumulative increased risk of new-onset MAFLD.PMID:38596503 | PMC:PMC11000085 | DOI:10.3748/wjg.v30.i10.1346 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Jing-Feng Chen Zhuo-Qing Wu Hao-Shuang Liu Su Yan You-Xiang Wang Miao Xing Xiao-Qin Song Su-Ying Ding Source Type: research

Establishment and validation of an adherence prediction system for lifestyle interventions in non-alcoholic fatty liver disease
CONCLUSION: The EDAS can reliably assess the adherence of patients with NAFLD to lifestyle interventions and have clinical application in this population.PMID:38596499 | PMC:PMC11000086 | DOI:10.3748/wjg.v30.i10.1393 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Ming-Hui Zeng Qi-Yu Shi Liang Xu Yu-Qiang Mi Source Type: research

Cumulative effects of excess high-normal alanine aminotransferase levels in relation to new-onset metabolic dysfunction-associated fatty liver disease in China
CONCLUSION: Most participants with MAFLD had normal ALT levels. Long-term high-normal ALT levels were associated with a cumulative increased risk of new-onset MAFLD.PMID:38596503 | PMC:PMC11000085 | DOI:10.3748/wjg.v30.i10.1346 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: Jing-Feng Chen Zhuo-Qing Wu Hao-Shuang Liu Su Yan You-Xiang Wang Miao Xing Xiao-Qin Song Su-Ying Ding Source Type: research

Establishment and validation of an adherence prediction system for lifestyle interventions in non-alcoholic fatty liver disease
CONCLUSION: The EDAS can reliably assess the adherence of patients with NAFLD to lifestyle interventions and have clinical application in this population.PMID:38596499 | PMC:PMC11000086 | DOI:10.3748/wjg.v30.i10.1393 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: Ming-Hui Zeng Qi-Yu Shi Liang Xu Yu-Qiang Mi Source Type: research

Cumulative effects of excess high-normal alanine aminotransferase levels in relation to new-onset metabolic dysfunction-associated fatty liver disease in China
CONCLUSION: Most participants with MAFLD had normal ALT levels. Long-term high-normal ALT levels were associated with a cumulative increased risk of new-onset MAFLD.PMID:38596503 | PMC:PMC11000085 | DOI:10.3748/wjg.v30.i10.1346 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Jing-Feng Chen Zhuo-Qing Wu Hao-Shuang Liu Su Yan You-Xiang Wang Miao Xing Xiao-Qin Song Su-Ying Ding Source Type: research

Establishment and validation of an adherence prediction system for lifestyle interventions in non-alcoholic fatty liver disease
CONCLUSION: The EDAS can reliably assess the adherence of patients with NAFLD to lifestyle interventions and have clinical application in this population.PMID:38596499 | PMC:PMC11000086 | DOI:10.3748/wjg.v30.i10.1393 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Ming-Hui Zeng Qi-Yu Shi Liang Xu Yu-Qiang Mi Source Type: research

Cumulative effects of excess high-normal alanine aminotransferase levels in relation to new-onset metabolic dysfunction-associated fatty liver disease in China
CONCLUSION: Most participants with MAFLD had normal ALT levels. Long-term high-normal ALT levels were associated with a cumulative increased risk of new-onset MAFLD.PMID:38596503 | PMC:PMC11000085 | DOI:10.3748/wjg.v30.i10.1346 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: Jing-Feng Chen Zhuo-Qing Wu Hao-Shuang Liu Su Yan You-Xiang Wang Miao Xing Xiao-Qin Song Su-Ying Ding Source Type: research

Establishment and validation of an adherence prediction system for lifestyle interventions in non-alcoholic fatty liver disease
CONCLUSION: The EDAS can reliably assess the adherence of patients with NAFLD to lifestyle interventions and have clinical application in this population.PMID:38596499 | PMC:PMC11000086 | DOI:10.3748/wjg.v30.i10.1393 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: Ming-Hui Zeng Qi-Yu Shi Liang Xu Yu-Qiang Mi Source Type: research

Deciphering the molecular pathways of saroglitazar: A dual PPAR α/γ agonist for managing metabolic NAFLD
Saroglitazar (SARO), a dual peroxisome proliferator activated receptor (PPAR)- α/γ agonist, has been used to treat metabolic diseases such as insulin resistance and diabetic dyslipidemia in patients with non-alcoholic fatty liver disease (NAFLD). SARO, administered at a dose of 4 mg/day, has been consistently studied in clinical trials with different time points ranging fr om 4 to 24 weeks with NAFLD patients. Due to its PPAR-γ agonistic action, SARO prevents adipose tissue-mediated fatty acid delivery to the liver by increasing insulin sensitivity and regulating adiponectin and leptin levels in adipose tissue. (Sou...
Source: Metabolism - Clinical and Experimental - April 10, 2024 Category: Biomedical Science Authors: Devaraj Ezhilarasan Tags: Review Source Type: research

Genes, Vol. 15, Pages 480: Effects of Fat and Carnitine on the Expression of Carnitine Acetyltransferase and Enoyl-CoA Hydratase Short-Chain 1 in the Liver of Juvenile GIFT (Oreochromis niloticus)
ang Yuda Li Carnitine acetyltransferase (CAT) and Enoyl-CoA hydratase short-chain 1 (ECHS1) are considered key enzymes that regulate the β-oxidation of fatty acids. However, very few studies have investigated their full length and expression in genetically improved farmed tilapia (GIFT, Oreochromis niloticus), an important aquaculture species in China. Here, we cloned CAT and ECHS1 full-length cDNA via the rapid amplification of cDNA ends, and the expressions of CAT and ECHS1 in the liver of juvenile GIFT were detected in different fat and carnitine diets, as were the changes in the lipometabolic enzymes...
Source: Genes - April 10, 2024 Category: Genetics & Stem Cells Authors: Ruijie Guo Kai Huang Kai Yu Jinghua Li Jiao Huang Dandan Wang Yuda Li Tags: Article Source Type: research

Remnant cholesterol is associated with the progression and regression of metabolic dysfunction-associated steatotic liver disease in Chinese adults
The prevalence of nonalcoholic fatty liver disease (NAFLD) has progressively increased over recent decades with increased rates of obesity and the rapid growth of the ageing population, affecting approximately 29% of the Chinese population (1). In addition to intrahepatic diseases such as liver cirrhosis and hepatocellular carcinoma, NAFLD has been demonstrated to increase the risks of multiple extrahepatic complications, including type 2 diabetes (T2DM), chronic kidney disease, cardiovascular disease (CVD), and even extrahepatic tumours (2,3). (Source: Journal of Clinical Lipidology)
Source: Journal of Clinical Lipidology - April 10, 2024 Category: Lipidology Authors: Wen Guo, Jing Lu, Xiaona Li, Xin Zhao, Nianzhen Xu, Qingqing Diao, Jue Jia, Qun Zhang Tags: Original Research Source Type: research

Association Between Liver Fibrosis Score and Diabetic Kidney Disease: A Retrospective Cross-Sectional Study of Hospitalized Patients
Conclusions NAFLD-FS and FIB-4 are strongly associated with DKD and risk for DKD progression in patients with T2DM. Additionally, sexual dimorphism exists in this association. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - April 10, 2024 Category: Endocrinology Authors: Zhang, Jie Chen, Shen Tian, Zhendong Cao, Jiarui Jiao, Yijie Wang, Bangqi Feng, Shenghui Luo, Zhanpeng Zhang, Qingfang Deng, Yuanyuan Cai, Wei Xu, Jixiong Tags: Article Source Type: research