Ependymoma from Benign to Highly Aggressive Diseases: A Review
Adv Tech Stand Neurosurg. 2024;50:31-62. doi: 10.1007/978-3-031-53578-9_2.ABSTRACTEpendymomas comprise biologically distinct tumor types with respect to age distribution, (epi)genetics, localization, and prognosis. Multimodal risk-stratification, including histopathological and molecular features, is essential in these biologically defined tumor types. Gross total resection (GTR), achieved with intraoperative monitoring and neuronavigation, and if necessary, second-look surgery, is the most effective treatment. Adjuvant radiation therapy is mandatory in high-risk tumors and in case of residual tumor. There is yet growing e...
Source: Advances and Technical Standards in Neurosurgery - April 9, 2024 Category: Neurosurgery Authors: Stephanie T J ünger Valentina Zschernack Martina Messing-J ünger Beate Timmermann Torsten Pietsch Source Type: research
Pediatric-Like Brain Tumors in Adults
Adv Tech Stand Neurosurg. 2024;50:147-183. doi: 10.1007/978-3-031-53578-9_5.ABSTRACTPediatric brain tumors are different to those found in adults in pathological type, anatomical site, molecular signature, and probable tumor drivers. Although these tumors usually occur in childhood, they also rarely present in adult patients, either as a de novo diagnosis or as a delayed recurrence of a pediatric tumor in the setting of a patient that has transitioned into adult services.Due to the rarity of pediatric-like tumors in adults, the literature on these tumor types in adults is often limited to small case series, and treatment d...
Source: Advances and Technical Standards in Neurosurgery - April 9, 2024 Category: Neurosurgery Authors: Sandra Fernandes Dias Oliver Richards Martin Elliot Paul Chumas Source Type: research
Ependymoma from Benign to Highly Aggressive Diseases: A Review
Adv Tech Stand Neurosurg. 2024;50:31-62. doi: 10.1007/978-3-031-53578-9_2.ABSTRACTEpendymomas comprise biologically distinct tumor types with respect to age distribution, (epi)genetics, localization, and prognosis. Multimodal risk-stratification, including histopathological and molecular features, is essential in these biologically defined tumor types. Gross total resection (GTR), achieved with intraoperative monitoring and neuronavigation, and if necessary, second-look surgery, is the most effective treatment. Adjuvant radiation therapy is mandatory in high-risk tumors and in case of residual tumor. There is yet growing e...
Source: Advances and Technical Standards in Neurosurgery - April 9, 2024 Category: Neurosurgery Authors: Stephanie T J ünger Valentina Zschernack Martina Messing-J ünger Beate Timmermann Torsten Pietsch Source Type: research
Pediatric-Like Brain Tumors in Adults
Adv Tech Stand Neurosurg. 2024;50:147-183. doi: 10.1007/978-3-031-53578-9_5.ABSTRACTPediatric brain tumors are different to those found in adults in pathological type, anatomical site, molecular signature, and probable tumor drivers. Although these tumors usually occur in childhood, they also rarely present in adult patients, either as a de novo diagnosis or as a delayed recurrence of a pediatric tumor in the setting of a patient that has transitioned into adult services.Due to the rarity of pediatric-like tumors in adults, the literature on these tumor types in adults is often limited to small case series, and treatment d...
Source: Advances and Technical Standards in Neurosurgery - April 9, 2024 Category: Neurosurgery Authors: Sandra Fernandes Dias Oliver Richards Martin Elliot Paul Chumas Source Type: research
Ependymoma from Benign to Highly Aggressive Diseases: A Review
Adv Tech Stand Neurosurg. 2024;50:31-62. doi: 10.1007/978-3-031-53578-9_2.ABSTRACTEpendymomas comprise biologically distinct tumor types with respect to age distribution, (epi)genetics, localization, and prognosis. Multimodal risk-stratification, including histopathological and molecular features, is essential in these biologically defined tumor types. Gross total resection (GTR), achieved with intraoperative monitoring and neuronavigation, and if necessary, second-look surgery, is the most effective treatment. Adjuvant radiation therapy is mandatory in high-risk tumors and in case of residual tumor. There is yet growing e...
Source: Advances and Technical Standards in Neurosurgery - April 9, 2024 Category: Neurosurgery Authors: Stephanie T J ünger Valentina Zschernack Martina Messing-J ünger Beate Timmermann Torsten Pietsch Source Type: research
Exploring disparities in surgical recommendations for patients with primary intramedullary spinal cord tumors: an analysis of the Surveillance, Epidemiology, and End Results database from 2000 to 2019
CONCLUSIONS: In patients with spinal ependymomas and nonependymal spinal gliomas, recommendations for surgery appear to be unaffected by patient sex, race, or income. Survival disparities appear to exist among unmarried, male, Black, and lower-income cohorts. Continued initiatives to identify drivers of disparities while improving health equity in this patient population are needed.PMID:38518290 | DOI:10.3171/2024.1.SPINE231093 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - March 22, 2024 Category: Neurosurgery Authors: Megan Parker Melanie A Horowitz Sachiv Chakravarti Jiaqi Liu Cathleen C Kuo Julian Gendreau Daniel Lubelski Jordina Rincon-Torroella Chetan Bettegowda Debraj Mukherjee Source Type: research
Exploring disparities in surgical recommendations for patients with primary intramedullary spinal cord tumors: an analysis of the Surveillance, Epidemiology, and End Results database from 2000 to 2019
CONCLUSIONS: In patients with spinal ependymomas and nonependymal spinal gliomas, recommendations for surgery appear to be unaffected by patient sex, race, or income. Survival disparities appear to exist among unmarried, male, Black, and lower-income cohorts. Continued initiatives to identify drivers of disparities while improving health equity in this patient population are needed.PMID:38518290 | DOI:10.3171/2024.1.SPINE231093 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - March 22, 2024 Category: Neurosurgery Authors: Megan Parker Melanie A Horowitz Sachiv Chakravarti Jiaqi Liu Cathleen C Kuo Julian Gendreau Daniel Lubelski Jordina Rincon-Torroella Chetan Bettegowda Debraj Mukherjee Source Type: research
Exploring disparities in surgical recommendations for patients with primary intramedullary spinal cord tumors: an analysis of the Surveillance, Epidemiology, and End Results database from 2000 to 2019
CONCLUSIONS: In patients with spinal ependymomas and nonependymal spinal gliomas, recommendations for surgery appear to be unaffected by patient sex, race, or income. Survival disparities appear to exist among unmarried, male, Black, and lower-income cohorts. Continued initiatives to identify drivers of disparities while improving health equity in this patient population are needed.PMID:38518290 | DOI:10.3171/2024.1.SPINE231093 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - March 22, 2024 Category: Neurosurgery Authors: Megan Parker Melanie A Horowitz Sachiv Chakravarti Jiaqi Liu Cathleen C Kuo Julian Gendreau Daniel Lubelski Jordina Rincon-Torroella Chetan Bettegowda Debraj Mukherjee Source Type: research
Exploring disparities in surgical recommendations for patients with primary intramedullary spinal cord tumors: an analysis of the Surveillance, Epidemiology, and End Results database from 2000 to 2019
CONCLUSIONS: In patients with spinal ependymomas and nonependymal spinal gliomas, recommendations for surgery appear to be unaffected by patient sex, race, or income. Survival disparities appear to exist among unmarried, male, Black, and lower-income cohorts. Continued initiatives to identify drivers of disparities while improving health equity in this patient population are needed.PMID:38518290 | DOI:10.3171/2024.1.SPINE231093 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - March 22, 2024 Category: Neurosurgery Authors: Megan Parker Melanie A Horowitz Sachiv Chakravarti Jiaqi Liu Cathleen C Kuo Julian Gendreau Daniel Lubelski Jordina Rincon-Torroella Chetan Bettegowda Debraj Mukherjee Source Type: research
Exploring disparities in surgical recommendations for patients with primary intramedullary spinal cord tumors: an analysis of the Surveillance, Epidemiology, and End Results database from 2000 to 2019
CONCLUSIONS: In patients with spinal ependymomas and nonependymal spinal gliomas, recommendations for surgery appear to be unaffected by patient sex, race, or income. Survival disparities appear to exist among unmarried, male, Black, and lower-income cohorts. Continued initiatives to identify drivers of disparities while improving health equity in this patient population are needed.PMID:38518290 | DOI:10.3171/2024.1.SPINE231093 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - March 22, 2024 Category: Neurosurgery Authors: Megan Parker Melanie A Horowitz Sachiv Chakravarti Jiaqi Liu Cathleen C Kuo Julian Gendreau Daniel Lubelski Jordina Rincon-Torroella Chetan Bettegowda Debraj Mukherjee Source Type: research
Exploring disparities in surgical recommendations for patients with primary intramedullary spinal cord tumors: an analysis of the Surveillance, Epidemiology, and End Results database from 2000 to 2019
CONCLUSIONS: In patients with spinal ependymomas and nonependymal spinal gliomas, recommendations for surgery appear to be unaffected by patient sex, race, or income. Survival disparities appear to exist among unmarried, male, Black, and lower-income cohorts. Continued initiatives to identify drivers of disparities while improving health equity in this patient population are needed.PMID:38518290 | DOI:10.3171/2024.1.SPINE231093 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - March 22, 2024 Category: Neurosurgery Authors: Megan Parker Melanie A Horowitz Sachiv Chakravarti Jiaqi Liu Cathleen C Kuo Julian Gendreau Daniel Lubelski Jordina Rincon-Torroella Chetan Bettegowda Debraj Mukherjee Source Type: research
Primary central nervous system tumors survival in children in ten Colombian cities: a VIGICANCER report
CONCLUSION: We found that half of Colombia's children and adolescents with primary CNS tumors survive five years, compared to 70% to 80% in high-income countries. In addition to tumor biology and location, gross total resection was crucial for improved survival in this cohort. Systematic monitoring of survival and its determinants provides empirical data for guiding cancer control policies.PMID:38505512 | PMC:PMC10949889 | DOI:10.3389/fonc.2023.1326788 (Source: Cancer Control)
Source: Cancer Control - March 20, 2024 Category: Cancer & Oncology Authors: Oscar Ramirez Vivian Piedrahita Jesus Ardila Carlos Pardo Edgar Cabrera-Bernal John Lopera Amaranto Suarez Carlos Andr és Portilla Carlos Narv áez Pamela Rodriguez Ximena Castro Ángel Castro Diego Ivan Estupinan-Perico Diana Valencia Mar ía Del Rosari Source Type: research
Convolutional neural network-based magnetic resonance image differentiation of filum terminale ependymomas from schwannomas
Preoperative diagnosis of filum terminale ependymomas (FTEs) versus schwannomas is difficult but essential for surgical planning and prognostic assessment. With the advancement of deep-learning approaches base... (Source: BMC Cancer)
Source: BMC Cancer - March 19, 2024 Category: Cancer & Oncology Authors: Zhaowen Gu, Wenli Dai, Jiarui Chen, Qixuan Jiang, Weiwei Lin, Qiangwei Wang, Jingyin Chen, Chi Gu, Jia Li, Guangyu Ying and Yongjian Zhu Tags: Research Source Type: research
Effects of cognitive-motor intervention for pediatric posterior fossa tumor survivors: results of a pilot study
AbstractThe purpose of this prospective pilot study was to evaluate the feasibility and effects of cognitive-motor intervention on the cognitive and motor abilities of pediatric survivors of posterior fossa tumors. The study involved patients aged 7 to 18 years with cognitive deficits who had completed primary treatment for posterior fossa tumors. 25 participants (Mage=11.3 ± 2.93, 64% male; 17 medulloblastoma, 1 ependymoma, 1 desmoplastic medulloblastoma, 6 piloid astrocytoma; 22 in remission (Mmonths =45), 3 in stabilization (Mmonths=49)) were recruited from the Research Institute for Brain Development and Peak Per...
Source: Journal of Neuro-Oncology - March 15, 2024 Category: Cancer & Oncology Source Type: research
Whole-tumor histogram analysis of postcontrast T1-weighted and apparent diffusion coefficient in predicting the grade and proliferative activity of adult intracranial ependymomas
ConclusionWhole-tumor histogram analysis of T1C and ADC may be a promising approach for predicting the grade and proliferative activity of adult intracranial ependymomas. (Source: Neuroradiology)
Source: Neuroradiology - March 13, 2024 Category: Radiology Source Type: research
