Metachronous Brain Tumors: Supratentorial Ependymoma Following Polymorphous Low-grade Neuroepithelial Tumor of the Young
Can J Neurol Sci. 2024 Apr 22:1-6. doi: 10.1017/cjn.2024.61. Online ahead of print.NO ABSTRACTPMID:38644627 | DOI:10.1017/cjn.2024.61 (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - April 22, 2024 Category: Neurology Authors: Nadav Gasner John Provias Jian-Qiang Lu Crystal Fong Source Type: research

Metachronous Brain Tumors: Supratentorial Ependymoma Following Polymorphous Low-grade Neuroepithelial Tumor of the Young
Can J Neurol Sci. 2024 Apr 22:1-6. doi: 10.1017/cjn.2024.61. Online ahead of print.NO ABSTRACTPMID:38644627 | DOI:10.1017/cjn.2024.61 (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - April 22, 2024 Category: Neurology Authors: Nadav Gasner John Provias Jian-Qiang Lu Crystal Fong Source Type: research

A cohort study of CNS tumors in Multiple Endocrine Neoplasia Type 1
CONCLUSIONS: Incidence of each CNS tumor was higher in the MEN1 population than in the French general population. Meningiomas and ependymomas should be considered part of the MEN1 syndrome, but somatic molecular data are missing to conclude for astrocytomas and schwannomas.PMID:38630553 | DOI:10.1158/1078-0432.CCR-23-3308 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - April 17, 2024 Category: Cancer & Oncology Authors: Thomas Graillon Pauline Romanet Clara Camilla Camille Gelin Romain Appay Catherine Roche Arnaud Lagarde Gr égory Mougel Kaissar Farah Ma ëlle Le Bras Julien Engelhardt Michel Kalamarides Matthieu Peyre Aymeric Amelot Evelyne Emery Elsa Magro Helene Cebu Source Type: research

A cohort study of CNS tumors in Multiple Endocrine Neoplasia Type 1
CONCLUSIONS: Incidence of each CNS tumor was higher in the MEN1 population than in the French general population. Meningiomas and ependymomas should be considered part of the MEN1 syndrome, but somatic molecular data are missing to conclude for astrocytomas and schwannomas.PMID:38630553 | DOI:10.1158/1078-0432.CCR-23-3308 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - April 17, 2024 Category: Cancer & Oncology Authors: Thomas Graillon Pauline Romanet Clara Camilla Camille Gelin Romain Appay Catherine Roche Arnaud Lagarde Gr égory Mougel Kaissar Farah Ma ëlle Le Bras Julien Engelhardt Michel Kalamarides Matthieu Peyre Aymeric Amelot Evelyne Emery Elsa Magro Helene Cebu Source Type: research

Cauda equina neuroendocrine tumor: a report of three cases and review of the literature with focus on differential diagnosis and postoperative management
We report on three patients, two of them presenting with a clinical history of lower back pain and sciatica. In all cases magnetic resonance imaging (MRI) of the lumbosacral spine with and without Gd-DTPA revealed an intradural lesion with strong contrast enhancement, first described as atypical ependymoma or schwannoma. A complete tumor resection was achieved in all cases, the histopathological diagnosis classified the tumors as CENETs.In our literature review, a total of 688 articles were screened and 162 patients were included. Patients demographic data, clinical symptoms, resection and recurrence were recorded.Discussi...
Source: Neurosurgical Review - April 17, 2024 Category: Neurosurgery Source Type: research

Ependymoma from Benign to Highly Aggressive Diseases: A Review
Adv Tech Stand Neurosurg. 2024;50:31-62. doi: 10.1007/978-3-031-53578-9_2.ABSTRACTEpendymomas comprise biologically distinct tumor types with respect to age distribution, (epi)genetics, localization, and prognosis. Multimodal risk-stratification, including histopathological and molecular features, is essential in these biologically defined tumor types. Gross total resection (GTR), achieved with intraoperative monitoring and neuronavigation, and if necessary, second-look surgery, is the most effective treatment. Adjuvant radiation therapy is mandatory in high-risk tumors and in case of residual tumor. There is yet growing e...
Source: Cancer Control - April 9, 2024 Category: Cancer & Oncology Authors: Stephanie T J ünger Valentina Zschernack Martina Messing-J ünger Beate Timmermann Torsten Pietsch Source Type: research

Pediatric-Like Brain Tumors in Adults
Adv Tech Stand Neurosurg. 2024;50:147-183. doi: 10.1007/978-3-031-53578-9_5.ABSTRACTPediatric brain tumors are different to those found in adults in pathological type, anatomical site, molecular signature, and probable tumor drivers. Although these tumors usually occur in childhood, they also rarely present in adult patients, either as a de novo diagnosis or as a delayed recurrence of a pediatric tumor in the setting of a patient that has transitioned into adult services.Due to the rarity of pediatric-like tumors in adults, the literature on these tumor types in adults is often limited to small case series, and treatment d...
Source: Advances and Technical Standards in Neurosurgery - April 9, 2024 Category: Neurosurgery Authors: Sandra Fernandes Dias Oliver Richards Martin Elliot Paul Chumas Source Type: research

Ependymoma from Benign to Highly Aggressive Diseases: A Review
Adv Tech Stand Neurosurg. 2024;50:31-62. doi: 10.1007/978-3-031-53578-9_2.ABSTRACTEpendymomas comprise biologically distinct tumor types with respect to age distribution, (epi)genetics, localization, and prognosis. Multimodal risk-stratification, including histopathological and molecular features, is essential in these biologically defined tumor types. Gross total resection (GTR), achieved with intraoperative monitoring and neuronavigation, and if necessary, second-look surgery, is the most effective treatment. Adjuvant radiation therapy is mandatory in high-risk tumors and in case of residual tumor. There is yet growing e...
Source: Advances and Technical Standards in Neurosurgery - April 9, 2024 Category: Neurosurgery Authors: Stephanie T J ünger Valentina Zschernack Martina Messing-J ünger Beate Timmermann Torsten Pietsch Source Type: research

Pediatric-Like Brain Tumors in Adults
Adv Tech Stand Neurosurg. 2024;50:147-183. doi: 10.1007/978-3-031-53578-9_5.ABSTRACTPediatric brain tumors are different to those found in adults in pathological type, anatomical site, molecular signature, and probable tumor drivers. Although these tumors usually occur in childhood, they also rarely present in adult patients, either as a de novo diagnosis or as a delayed recurrence of a pediatric tumor in the setting of a patient that has transitioned into adult services.Due to the rarity of pediatric-like tumors in adults, the literature on these tumor types in adults is often limited to small case series, and treatment d...
Source: Advances and Technical Standards in Neurosurgery - April 9, 2024 Category: Neurosurgery Authors: Sandra Fernandes Dias Oliver Richards Martin Elliot Paul Chumas Source Type: research

Ependymoma from Benign to Highly Aggressive Diseases: A Review
Adv Tech Stand Neurosurg. 2024;50:31-62. doi: 10.1007/978-3-031-53578-9_2.ABSTRACTEpendymomas comprise biologically distinct tumor types with respect to age distribution, (epi)genetics, localization, and prognosis. Multimodal risk-stratification, including histopathological and molecular features, is essential in these biologically defined tumor types. Gross total resection (GTR), achieved with intraoperative monitoring and neuronavigation, and if necessary, second-look surgery, is the most effective treatment. Adjuvant radiation therapy is mandatory in high-risk tumors and in case of residual tumor. There is yet growing e...
Source: Advances and Technical Standards in Neurosurgery - April 9, 2024 Category: Neurosurgery Authors: Stephanie T J ünger Valentina Zschernack Martina Messing-J ünger Beate Timmermann Torsten Pietsch Source Type: research

Pediatric-Like Brain Tumors in Adults
Adv Tech Stand Neurosurg. 2024;50:147-183. doi: 10.1007/978-3-031-53578-9_5.ABSTRACTPediatric brain tumors are different to those found in adults in pathological type, anatomical site, molecular signature, and probable tumor drivers. Although these tumors usually occur in childhood, they also rarely present in adult patients, either as a de novo diagnosis or as a delayed recurrence of a pediatric tumor in the setting of a patient that has transitioned into adult services.Due to the rarity of pediatric-like tumors in adults, the literature on these tumor types in adults is often limited to small case series, and treatment d...
Source: Advances and Technical Standards in Neurosurgery - April 9, 2024 Category: Neurosurgery Authors: Sandra Fernandes Dias Oliver Richards Martin Elliot Paul Chumas Source Type: research

Ependymoma from Benign to Highly Aggressive Diseases: A Review
Adv Tech Stand Neurosurg. 2024;50:31-62. doi: 10.1007/978-3-031-53578-9_2.ABSTRACTEpendymomas comprise biologically distinct tumor types with respect to age distribution, (epi)genetics, localization, and prognosis. Multimodal risk-stratification, including histopathological and molecular features, is essential in these biologically defined tumor types. Gross total resection (GTR), achieved with intraoperative monitoring and neuronavigation, and if necessary, second-look surgery, is the most effective treatment. Adjuvant radiation therapy is mandatory in high-risk tumors and in case of residual tumor. There is yet growing e...
Source: Advances and Technical Standards in Neurosurgery - April 9, 2024 Category: Neurosurgery Authors: Stephanie T J ünger Valentina Zschernack Martina Messing-J ünger Beate Timmermann Torsten Pietsch Source Type: research

Pediatric-Like Brain Tumors in Adults
Adv Tech Stand Neurosurg. 2024;50:147-183. doi: 10.1007/978-3-031-53578-9_5.ABSTRACTPediatric brain tumors are different to those found in adults in pathological type, anatomical site, molecular signature, and probable tumor drivers. Although these tumors usually occur in childhood, they also rarely present in adult patients, either as a de novo diagnosis or as a delayed recurrence of a pediatric tumor in the setting of a patient that has transitioned into adult services.Due to the rarity of pediatric-like tumors in adults, the literature on these tumor types in adults is often limited to small case series, and treatment d...
Source: Advances and Technical Standards in Neurosurgery - April 9, 2024 Category: Neurosurgery Authors: Sandra Fernandes Dias Oliver Richards Martin Elliot Paul Chumas Source Type: research

Ependymoma from Benign to Highly Aggressive Diseases: A Review
Adv Tech Stand Neurosurg. 2024;50:31-62. doi: 10.1007/978-3-031-53578-9_2.ABSTRACTEpendymomas comprise biologically distinct tumor types with respect to age distribution, (epi)genetics, localization, and prognosis. Multimodal risk-stratification, including histopathological and molecular features, is essential in these biologically defined tumor types. Gross total resection (GTR), achieved with intraoperative monitoring and neuronavigation, and if necessary, second-look surgery, is the most effective treatment. Adjuvant radiation therapy is mandatory in high-risk tumors and in case of residual tumor. There is yet growing e...
Source: Advances and Technical Standards in Neurosurgery - April 9, 2024 Category: Neurosurgery Authors: Stephanie T J ünger Valentina Zschernack Martina Messing-J ünger Beate Timmermann Torsten Pietsch Source Type: research

Pediatric-Like Brain Tumors in Adults
Adv Tech Stand Neurosurg. 2024;50:147-183. doi: 10.1007/978-3-031-53578-9_5.ABSTRACTPediatric brain tumors are different to those found in adults in pathological type, anatomical site, molecular signature, and probable tumor drivers. Although these tumors usually occur in childhood, they also rarely present in adult patients, either as a de novo diagnosis or as a delayed recurrence of a pediatric tumor in the setting of a patient that has transitioned into adult services.Due to the rarity of pediatric-like tumors in adults, the literature on these tumor types in adults is often limited to small case series, and treatment d...
Source: Advances and Technical Standards in Neurosurgery - April 9, 2024 Category: Neurosurgery Authors: Sandra Fernandes Dias Oliver Richards Martin Elliot Paul Chumas Source Type: research