Adult cerebral high-grade glioneuronal tumor with perivascular or pseudopapillary growth co-existing with low-grade tumor: a case report
Int J Clin Exp Pathol. 2023 Oct 15;16(10):294-302. eCollection 2023.ABSTRACTAn unusual, small cell-predominant, high-grade glioneuronal tumor in the occipital lobe of a 49-year-old man that co-existed with a low-grade tumor is reported. The tumor consisted of two distinct components: the major component was a dense proliferation of primitive small cells showing bidirectional neuronal and glial differentiation; and the minor component consisted of a proliferation of well-differentiated astrocytes intermingled with mature neuronal cells. In the former component, perivascular pseudorosette-like or pseudopapillary growth remin...
Source: International Journal of Clinical and Experimental Pathology - November 16, 2023 Category: Pathology Authors: Masayuki Shintaku Makoto Ohta Hideo Chihara Hideaki Yokoo Yuri Noda Koji Tsuta Source Type: research

Adult cerebral high-grade glioneuronal tumor with perivascular or pseudopapillary growth co-existing with low-grade tumor: a case report
Int J Clin Exp Pathol. 2023 Oct 15;16(10):294-302. eCollection 2023.ABSTRACTAn unusual, small cell-predominant, high-grade glioneuronal tumor in the occipital lobe of a 49-year-old man that co-existed with a low-grade tumor is reported. The tumor consisted of two distinct components: the major component was a dense proliferation of primitive small cells showing bidirectional neuronal and glial differentiation; and the minor component consisted of a proliferation of well-differentiated astrocytes intermingled with mature neuronal cells. In the former component, perivascular pseudorosette-like or pseudopapillary growth remin...
Source: International Journal of Clinical and Experimental Pathology - November 16, 2023 Category: Pathology Authors: Masayuki Shintaku Makoto Ohta Hideo Chihara Hideaki Yokoo Yuri Noda Koji Tsuta Source Type: research

Adult cerebral high-grade glioneuronal tumor with perivascular or pseudopapillary growth co-existing with low-grade tumor: a case report
Int J Clin Exp Pathol. 2023 Oct 15;16(10):294-302. eCollection 2023.ABSTRACTAn unusual, small cell-predominant, high-grade glioneuronal tumor in the occipital lobe of a 49-year-old man that co-existed with a low-grade tumor is reported. The tumor consisted of two distinct components: the major component was a dense proliferation of primitive small cells showing bidirectional neuronal and glial differentiation; and the minor component consisted of a proliferation of well-differentiated astrocytes intermingled with mature neuronal cells. In the former component, perivascular pseudorosette-like or pseudopapillary growth remin...
Source: International Journal of Clinical and Experimental Pathology - November 16, 2023 Category: Pathology Authors: Masayuki Shintaku Makoto Ohta Hideo Chihara Hideaki Yokoo Yuri Noda Koji Tsuta Source Type: research

Adult cerebral high-grade glioneuronal tumor with perivascular or pseudopapillary growth co-existing with low-grade tumor: a case report
Int J Clin Exp Pathol. 2023 Oct 15;16(10):294-302. eCollection 2023.ABSTRACTAn unusual, small cell-predominant, high-grade glioneuronal tumor in the occipital lobe of a 49-year-old man that co-existed with a low-grade tumor is reported. The tumor consisted of two distinct components: the major component was a dense proliferation of primitive small cells showing bidirectional neuronal and glial differentiation; and the minor component consisted of a proliferation of well-differentiated astrocytes intermingled with mature neuronal cells. In the former component, perivascular pseudorosette-like or pseudopapillary growth remin...
Source: International Journal of Clinical and Experimental Pathology - November 16, 2023 Category: Pathology Authors: Masayuki Shintaku Makoto Ohta Hideo Chihara Hideaki Yokoo Yuri Noda Koji Tsuta Source Type: research

Adult cerebral high-grade glioneuronal tumor with perivascular or pseudopapillary growth co-existing with low-grade tumor: a case report
Int J Clin Exp Pathol. 2023 Oct 15;16(10):294-302. eCollection 2023.ABSTRACTAn unusual, small cell-predominant, high-grade glioneuronal tumor in the occipital lobe of a 49-year-old man that co-existed with a low-grade tumor is reported. The tumor consisted of two distinct components: the major component was a dense proliferation of primitive small cells showing bidirectional neuronal and glial differentiation; and the minor component consisted of a proliferation of well-differentiated astrocytes intermingled with mature neuronal cells. In the former component, perivascular pseudorosette-like or pseudopapillary growth remin...
Source: International Journal of Clinical and Experimental Pathology - November 16, 2023 Category: Pathology Authors: Masayuki Shintaku Makoto Ohta Hideo Chihara Hideaki Yokoo Yuri Noda Koji Tsuta Source Type: research

Adult cerebral high-grade glioneuronal tumor with perivascular or pseudopapillary growth co-existing with low-grade tumor: a case report
Int J Clin Exp Pathol. 2023 Oct 15;16(10):294-302. eCollection 2023.ABSTRACTAn unusual, small cell-predominant, high-grade glioneuronal tumor in the occipital lobe of a 49-year-old man that co-existed with a low-grade tumor is reported. The tumor consisted of two distinct components: the major component was a dense proliferation of primitive small cells showing bidirectional neuronal and glial differentiation; and the minor component consisted of a proliferation of well-differentiated astrocytes intermingled with mature neuronal cells. In the former component, perivascular pseudorosette-like or pseudopapillary growth remin...
Source: International Journal of Clinical and Experimental Pathology - November 16, 2023 Category: Pathology Authors: Masayuki Shintaku Makoto Ohta Hideo Chihara Hideaki Yokoo Yuri Noda Koji Tsuta Source Type: research

Brain Tumors in Adolescents and Young Adults: A Review
Semin Neurol DOI: 10.1055/s-0043-1776775Brain tumors account for the majority of cancer-related deaths in adolescents and young adults (AYAs), defined as individuals aged 15 to 39. AYAs constitute a distinct population in which both pediatric- and adult-type central nervous system (CNS) tumors can be observed. Clinical manifestations vary depending on tumor location and often include headaches, seizures, focal neurological deficits, and signs of increased intracranial pressure. With the publication of the updated World Health Organization CNS tumor classification in 2021, diagnoses have been redefined to emphasize key mole...
Source: Seminars in Neurology - November 10, 2023 Category: Neurology Authors: Rousseau, Julien Bennett, Julie Lim-Fat, Mary Jane Tags: Review Article Source Type: research

Classification and Grading of Central Nervous System Tumors According to the World Health Organization 5th Edition
Semin Neurol DOI: 10.1055/s-0043-1776793The World Health Organization (WHO) released the 5th edition of its classification of central nervous system (CNS) tumors in 2021. Advances in the landscape of molecular tumor pathophysiology prompted major revisions to the previous edition released in 2016, some of which were first introduced by the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy—Not Official WHO (cIMPACT-NOW). The 2021 classification system integrates newly gained molecular insights to guide changes in tumor taxonomy and nomenclature, introduces several new types of tumors, and expan...
Source: Seminars in Neurology - November 10, 2023 Category: Neurology Authors: Yoda, Rebecca A. Cimino, Patrick J. Tags: Review Article Source Type: research

Resection of a lumbar intradural tumor
CONCLUSION: Early intervention and gross total resection of spinal intradural tumors are associated with optimal patient outcomes. Additional adjuncts, such as ultrasound, are beneficial and can help achieve gross total tumor resection.PMID:37941626 | PMC:PMC10629344 | DOI:10.25259/SNI_770_2023 (Source: Surgical Neurology International)
Source: Surgical Neurology International - November 9, 2023 Category: Neurosurgery Authors: Joseph Yunga Tigre Andrew J Kloehn Ava Scemama James Boddu Meredith C Costello Allan D Levi S Shelby Burks Source Type: research