Cerebral Aneurysm in Association with Left Atrial Myxoma.
PMID: 31203822 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - June 17, 2019 Category: Neurology Authors: Alrohimi A, Putko BN, Jeffery D, Van Dijk R, Chow M, McCombe JA Tags: Can J Neurol Sci Source Type: research

IncobotulinumtoxinA and Deep Brain Stimulation.
Abstract Guidelines recommend Botulinum toxin-A (BoNT-A) after deep brain stimulation (DBS), although the effectiveness of their combined use is uncertain. A chart review of Parkinson's disease (17) and dystonia (7) patients undergoing 302 injections with IncobotulinumtoxinA before or after DBS was performed. Patients with cervical dystonia received less IncobotulinumtoxinA after DBS (290.7 ± 124.0 vs. 192.4 ± 131.4, p = 0.005) and experienced an increased benefit (4.0 ± 3.4 vs. 8.4 ± 3.6 weeks, p = 0.003). No significant differences were found when comparing the treatment outcomes of 1...
Source: The Canadian Journal of Neurological Sciences - June 14, 2019 Category: Neurology Authors: Soh D, Fasano A Tags: Can J Neurol Sci Source Type: research

Bilateral Chorea Associated with Acute Caudate Nucleus Infarctions.
PMID: 31199214 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - June 14, 2019 Category: Neurology Authors: Qu Y, Jin H, Guo ZN, Zhang FL, Liu J, Qin HQ, Yang Y Tags: Can J Neurol Sci Source Type: research

Neurological Worsening After Implantable Pulse Generator Replacement.
CONCLUSION: Neurological worsening followed 27.4% of IPG replacements in PD cases on CDT with approximately 82.4% of these being avoidable by carefully monitoring stimulation parameters to match pre-replacement TEED values. PMID: 31189485 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - June 13, 2019 Category: Neurology Authors: Kumar N, Murgai A, Jog M Tags: Can J Neurol Sci Source Type: research

Intracerebral and Spinal Subarachnoid Hemorrhage in Eosinophilic Polyangiitis.
PMID: 31179954 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - June 10, 2019 Category: Neurology Authors: Southam C, Hahn C Tags: Can J Neurol Sci Source Type: research

Coma Recovery Scale-Revised with and without the emotional stimulation of caregivers.
PMID: 31179958 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - June 10, 2019 Category: Neurology Authors: Formisano R, Contrada M, Iosa M, Ferri G, Schiattone S, Aloisi M Tags: Can J Neurol Sci Source Type: research

Hyperacute Infarct on intra-operative diffusion imaging of pediatric brain tumor surgery.
CONCLUSIONS: Hyperacute infarcts are not rare events to complicate pediatric brain tumor resection. Tumoral encasement of the circle of Willis vessels appears to be the main risk factor. Intraoperative DWI underestimates the final extent of infarcted tissue compared to early post-surgical MRI. PMID: 31179961 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - June 10, 2019 Category: Neurology Authors: Saint-Martin C, Apuzzo S, Salman A, Farmer JP Tags: Can J Neurol Sci Source Type: research

An Evolving Therapy - Dural Venous Sinus Stenting for Idiopathic Intracranial Hypertension.
PMID: 31179964 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - June 10, 2019 Category: Neurology Authors: Chatterjee R, Nascimento FA, Diaz-Marchan PJ, Chen SR, Nunez-Wallace KR Tags: Can J Neurol Sci Source Type: research

White Matter Hyperintensities Predict Cognitive Decline: A Community-Based Study.
CONCLUSIONS: The severity of WMHs at baseline was associated with cognitive decline in the non-demented elderly over time. Interventions on WMH lesions may offer some benefits for cognitive deterioration. PMID: 31133080 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - May 28, 2019 Category: Neurology Authors: Qi X, Tang H, Luo Q, Ding B, Chen J, Cui P, Chen S, Ling H, Ma J Tags: Can J Neurol Sci Source Type: research

Predictors of Collegiate Student-Athletes' Concussion-Related Knowledge and Behaviors.
PMID: 31124763 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - May 24, 2019 Category: Neurology Authors: Bernstein JP, Calamia M, Mullenix S Tags: Can J Neurol Sci Source Type: research

Adolescent stiff person syndrome: long term symptom remission on immunomodulatory therapy.
PMID: 31124765 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - May 24, 2019 Category: Neurology Authors: Ogilvie RJ, Kolski HK Tags: Can J Neurol Sci Source Type: research

A Rare Case of Central Nervous System Involvement with Chronic Lymphocytic Leukemia.
PMID: 31120004 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - May 23, 2019 Category: Neurology Authors: Witton LA, Menon S, Perera KS Tags: Can J Neurol Sci Source Type: research

Use of Antiepileptic Drugs in Aneurysmal Subarachnoid Hemorrhage.
CONCLUSION: The presence of MLS was an independent predictor of seizure activity in patients with aneurysmal SAH. AED prophylaxis prescribing patterns seemed arbitrary and was not informed by identifiable clinical factors or true risk factors for seizure. A current lack of evidence guiding AED prescribing practice highlights the need for larger studies in this patient population. PMID: 31113497 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - May 22, 2019 Category: Neurology Authors: Dmytriw AA, Maragkos GA, Zuccato J, Singh JM, Wilcox ME, Schweikert S Tags: Can J Neurol Sci Source Type: research

Clinical Course of Relapsing Remitting Multiple Sclerosis Post-Natalizumab.
In conclusion, fingolimod is an effective therapy post-natalizumab. PMID: 31113500 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - May 22, 2019 Category: Neurology Authors: Fiander MDJ, Bhan V, Stewart SA, Parks NE Tags: Can J Neurol Sci Source Type: research

Laboratory Monitoring Practices Among Canadian Multiple Sclerosis Clinicians.
CONCLUSIONS: This nation-wide survey showed variability in infrastructure used in laboratory monitoring and regional variation in nursing involvement. Providers' level of concern for laboratory monitoring for DMTs did not vary by years of experience or volume of MS patients followed, suggesting that improved systems, rather than education, could ameliorate perceptions of risk. PMID: 31111800 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - May 21, 2019 Category: Neurology Authors: Atwal A, Schabas A, Head J, Taylor C, Traboulsee A, Barclay K, Carruthers R Tags: Can J Neurol Sci Source Type: research

What to Do When the Electromyographer is "Noisy".
What to Do When the Electromyographer is "Noisy". Can J Neurol Sci. 2019 May 21;:1 Authors: Robinson LR PMID: 31112111 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - May 21, 2019 Category: Neurology Authors: Robinson LR Tags: Can J Neurol Sci Source Type: research

Aperiodic Alternating Nystagmus in Lateral Medullary Strokes.
PMID: 31104641 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - May 20, 2019 Category: Neurology Authors: Kim SH, Kim JS Tags: Can J Neurol Sci Source Type: research

"The Other Side of the Coin": Hemorrhagic Stroke in Congenital Hypofibrinogenemia.
"The Other Side of the Coin": Hemorrhagic Stroke in Congenital Hypofibrinogenemia. Can J Neurol Sci. 2019 May 17;:1-2 Authors: Jimenez-Ruiz A, Gutierrez-Castillo A, Ruiz-Sandoval JL PMID: 31097049 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - May 17, 2019 Category: Neurology Authors: Jimenez-Ruiz A, Gutierrez-Castillo A, Ruiz-Sandoval JL Tags: Can J Neurol Sci Source Type: research

Venous sinus stenosis causing isolated pulsatile tinnitus.
PMID: 31088590 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - May 15, 2019 Category: Neurology Authors: Quintas-Neves M, Freitas E, Amorim JM, Rocha J, Pinho J Tags: Can J Neurol Sci Source Type: research

Facial Diplegia in Neuroinvasive West Nile Virus Infection.
PMID: 31060643 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - May 7, 2019 Category: Neurology Authors: Chan TLH, Budhram A Tags: Can J Neurol Sci Source Type: research

Anti-CV2-Associated Paraneoplastic Hemichorea Secondary to Diffuse Large B-cell Lymphoma.
PMID: 31057136 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - May 6, 2019 Category: Neurology Authors: Nevison S, Rizek P Tags: Can J Neurol Sci Source Type: research

Infantile-Onset Multisystem Neurologic, Endocrine, and Pancreatic Disease: Case and Review.
We report three brothers born to consanguineous parents of Syrian descent, with a homozygous novel c.324G>A (p.W108*) mutation in PTRH2 that encodes peptidyl-tRNA hydrolase 2, causing infantile-onset multisystem neurologic, endocrine, and pancreatic disease (IMNEPD). We describe the core clinical features of postnatal microcephaly, motor and language delay with regression, ataxia, and hearing loss. Additional features include epileptic seizures, pancreatic insufficiency, and peripheral neuropathy. Clinical phenotyping enabled a targeted approach to the investigation and identification of a novel homozygous nonsense ...
Source: The Canadian Journal of Neurological Sciences - May 6, 2019 Category: Neurology Authors: Le C, Prasad AN, Rupar CA, Debicki D, Andrade A, Prasad C Tags: Can J Neurol Sci Source Type: research

Consultation and Surgical Wait Times in Cervical Spondylotic Myelopathy.
CONCLUSIONS: Patients with shorter duration (either symptoms or medication) and less neck pain waited less to see a spine specialist in Canada and to undergo surgical treatment. This study highlights some of the obstacles to overcome in expedited care for this patient population. PMID: 31046861 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - May 3, 2019 Category: Neurology Authors: Sharifi B, McIntosh G, Fisher C, Jacobs WB, Johnson M, Bailey CS, Christie S, Charest-Morin R, Paquet J, Nataraj A, Cadotte D, Manson N, Hall H, Thomas KC, Rampersaud YR, Dea N Tags: Can J Neurol Sci Source Type: research

White Matter Damage in the Semantic Variant of Primary Progressive Aphasia.
CONCLUSIONS: This syndrome appears to be associated not only with GM but also significant WM degeneration. Thus, DTI could play a role in the differential diagnosis of atypical dementia by specifying WM damage specific to svPPA. PMID: 31030675 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - April 29, 2019 Category: Neurology Authors: Bouchard LO, Wilson MA, Laforce R, Duchesne S Tags: Can J Neurol Sci Source Type: research

A Preliminary Analysis of a Home-Based Stroke Rehabilitation Program in Windsor, Ontario.
Abstract Community stroke rehabilitation (CSR) is an effective program for survivors to recover at home supported by a multidisciplinary team. A home-based, specialized CSR program was delivered in Windsor, Ontario, to stroke patients who faced barriers to accessing outpatient services following inpatient rehabilitation. Preliminary results show program patients made significant functional improvements from baseline to program discharge. A subgroup analysis revealed that, after adjusting for age and resource intensity, moderate to severe stroke patients made greater functional gains compared to mild stroke patient...
Source: The Canadian Journal of Neurological Sciences - April 29, 2019 Category: Neurology Authors: Voth J, Petro J, Mallender M, Bridgen S, Mannan S, Jackson M, Liem NR Tags: Can J Neurol Sci Source Type: research

Continuous Electroencephalography Monitoring for Critically Ill Neonates: A Canadian Perspective.
CONCLUSIONS: Canadian neurologists and neonatologists do not agree on the best monitoring approach for critically ill neonates. Furthermore, neonatologists perceive a smaller cEEG monitoring gap as compared with neurologists. However, many participants from both specialties would like to increase long-term EEG monitoring in the NICU setting. Facilitating access to EEG monitoring and enhancing education may help to address these needs. PMID: 31030685 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - April 29, 2019 Category: Neurology Authors: Buttle SG, Sell E, Webster R, Varin M, Lemyre B, Hahn C, Pohl D Tags: Can J Neurol Sci Source Type: research

Reflex Seizures in a Patient with CDKL5 Deficiency Disorder.
PMID: 31030687 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - April 29, 2019 Category: Neurology Authors: Peikes T, Hartley JN, Mhanni AA, Greenberg CR, Appendino JP Tags: Can J Neurol Sci Source Type: research

Recent Trends in Neurosurgery Career Outcomes in Canada.
CONCLUSIONS: Underemployment in neurosurgery has become a significant issue in Canada for various reasons. Pursuit of in-folded research, but not fellowship training, was associated with obtaining full employment. PMID: 31010443 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - April 23, 2019 Category: Neurology Authors: Tso MK, Max Findlay J, Lownie SP, Chris Wallace M, Toyota BD, Fleetwood IG Tags: Can J Neurol Sci Source Type: research

Meningeal Myelomatosis Illustrated on FLAIR Post-Contrasted Images.
PMID: 31010448 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - April 23, 2019 Category: Neurology Authors: Silva N, Delamain M, Duarte G, Reis F Tags: Can J Neurol Sci Source Type: research

Characteristic Cerebrovascular Findings Associated with ACTA2 Gene Mutations.
Abstract A specific mutation (Arg179) of the ACTA2 gene has previously been described to cause a syndrome of multisystemic smooth muscle dysfunction with an extremely characteristic cerebrovascular appearance.1 Accurate neuroimaging diagnosis of this entity is important as this syndrome predisposes to complications such as early-onset ischemic stroke and ascending thoracic aortic aneurysm.2,3 The following case demonstrates a previously undescribed ACTA2 mutation (Met46) with an identical cerebrovascular imaging appearance to that of Arg179 mutations, but a less severe overall phenotype. PMID: 30975232 [PubMe...
Source: The Canadian Journal of Neurological Sciences - April 12, 2019 Category: Neurology Authors: Zhang A, Jo A, Grajewski K, Kim J Tags: Can J Neurol Sci Source Type: research

Psychiatric Neurosurgery: A Survey on the Perceptions of Psychiatrists and Residents.
CONCLUSION: Overall, participants acknowledged having many limitations to referring patients for neurosurgical interventions. While informative conferences discussing neuromodulation/neuroablation could easily address many barriers, further studies are required to assess how these could change attitudes and patterns of referral. PMID: 30975240 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - April 12, 2019 Category: Neurology Authors: Cormier J, Iorio-Morin C, Mathieu D, Ducharme S Tags: Can J Neurol Sci Source Type: research

Step on the Gas! Focal Seizures with Autonomic Features.
PMID: 30944049 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - April 4, 2019 Category: Neurology Authors: Plecash A, Wile D Tags: Can J Neurol Sci Source Type: research

Rowan's Rugby Fatality Prompts Canada's First Concussion Legislation.
PMID: 30945631 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - April 4, 2019 Category: Neurology Authors: Tator C, Starkes J, Dolansky G, Quet J, Michaud J, Vassilyadi M Tags: Can J Neurol Sci Source Type: research

Fatal Second Impact Syndrome in Rowan Stringer, A 17-Year-Old Rugby Player.
We report a case of SIS in Rowan Stringer, age 17, a rugby player who sustained a fatal brain injury despite prompt medical therapy including decompression surgery. The cause of the massive brain swelling was initially unknown. An inquest revealed Rowan's text messages to friends describing symptoms from two prior, recent rugby brain injuries, likely concussions, within 5 days of the fatal blow and confirming the diagnosis of SIS. PMID: 30945632 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - April 4, 2019 Category: Neurology Authors: Tator C, Starkes J, Dolansky G, Quet J, Michaud J, Vassilyadi M Tags: Can J Neurol Sci Source Type: research

Eagle Syndrome as a Cause of Cerebral Venous Sinus Thrombosis.
Abstract A 15-year-old teenager presented with a 2-month history of headache. Neurological examination was normal except for papilledema. Further lumbar puncture indicated intracranial hypertension (330 mm H2O). Brain magnetic resonance imaging (MRI) was normal but phase contrast-magnetic resonance venography (PC-MRV) (Figure 1(A)) suggested possible left transverse-sigmoid sinus thrombosis; subsequent contrast-enhanced 3D fat-saturated T1 volumetric isotropic turbo spin echo acquisition (VISTA) MRI (Figure 1(B)) confirmed the pathology. Hyper-coagulable panel results (including six steroid sex hormones, antithrom...
Source: The Canadian Journal of Neurological Sciences - April 1, 2019 Category: Neurology Authors: Zhang FL, Zhou HW, Guo ZN, Yang Y Tags: Can J Neurol Sci Source Type: research

Incidentaloma Discoveries in the Course of Neuroimaging Research.
We present recommendations on how to appropriately inform patients or participants of the accidental findings. Additionally, we propose specific suggestions pertaining to the clinical research setting aimed for investigators and psychiatrists. Unlike current articles pertaining to incidentaloma, the current report provides a distinct focus on psychiatric issues and specific recommendations for studies involving psychiatric patients. PMID: 30932801 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - April 1, 2019 Category: Neurology Authors: Stip E, Miron JP, Nolin M, Letourneau G, Bernazzani O, Chamelian L, Boileau B, Gupta M, Luck D, Lungu O Tags: Can J Neurol Sci Source Type: research

A Survey of Cerebrospinal Fluid Total Protein Upper Limits in Canada: Time for an Update?
CONCLUSIONS: Recent well-powered laboratory reference studies have documented CSF-TP upper reference limits that are above 0.6 g/L starting at age 50, with incremental limits partitioned by subsequent decades of age. The conventional 0.45 g/L limit could lead to false positive results. Our survey suggests there is a need to consider a wide adoption of data-driven, rather than historical, reference values. PMID: 30915935 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - March 27, 2019 Category: Neurology Authors: Bourque PR, McCudden CR, Warman-Chardon J, Brooks J, Hegen H, Deisenhammer F, Breiner A Tags: Can J Neurol Sci Source Type: research

Effects of Deep Brain Stimulation of the Subthalamic Nucleus Settings on Voice Quality, Intensity, and Prosody in Parkinson's Disease: Preliminary Evidence for Speech Optimization.
CONCLUSIONS: This study provides preliminary evidence that STN-DBS may be optimized for Parkinson-related problems with voice quality, speech intensity, and prosody of speech. PMID: 30905324 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - March 25, 2019 Category: Neurology Authors: Abeyesekera A, Adams S, Mancinelli C, Knowles T, Gilmore G, Delrobaei M, Jog M Tags: Can J Neurol Sci Source Type: research

Intrathecal Trastuzumab as a Potential Cause of Drug-Induced Aseptic Meningitis.
PMID: 30905325 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - March 25, 2019 Category: Neurology Authors: Pappa E, Conforti R, Hoang-Xuan K, Alentorn A Tags: Can J Neurol Sci Source Type: research

Effect of Head Rotation on Jugular Vein Patency Under General Anesthesia.
Abstract Head rotation causes compression and occlusion of the ipsilateral internal jugular (IJ) vein. This can result in raised intracranial pressure and increased bleeding if the patient is having or has recently had surgery. The amount of head rotation in adults resulting in occlusion of the ipsilateral IJ vein is unknown however. We measured the amount of head turn that produced occlusion of the ipsilateral IJ vein in 25 patients having surgery under general anesthesia. On average, 80% of IJ veins occlude at a mean of 55.6° on the left and 53.3° on the right. PMID: 30905329 [PubMed - as supplied b...
Source: The Canadian Journal of Neurological Sciences - March 25, 2019 Category: Neurology Authors: Burbridge MA, Min JG, Jaffe RA Tags: Can J Neurol Sci Source Type: research

Factors Associated with Having a Will, Power of Attorney, and Advanced Healthcare Directive in Patients Presenting to a Rural and Remote Memory Clinic.
CONCLUSIONS: Our results indicate that poor quality of life, good performance on verbal fluency, Indigenous ethnicity, and living with others are associated with a lower likelihood of legal documents in patients with dementia. These factors can help physicians identify patients at risk of leaving their legal affairs unattended to. Physicians should discuss the creation of legal documents early on in patients with signs of dementia. PMID: 30907330 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - March 25, 2019 Category: Neurology Authors: Lee S, Kirk A, Kirk EA, Karunanayake C, O'Connell ME, Morgan D Tags: Can J Neurol Sci Source Type: research

Standards of Practice in Acute Ischemic Stroke Intervention International Recommendations.
Yoshimura SI, Biscoito L, Pumar M, Diaz O, Fraser J, Lifante I, Liebeskind DS, Nogueira RG, Hacke W, Brainin M, Yan B, Soderman M, Taylor A, Pongpech S, Terbrugge K Abstract After five positive randomized controlled trials showed benefit of mechanical thrombectomy in the management of acute ischemic stroke with emergent large-vessel occlusion, a multi-society meeting was organized during the 17th Congress of the World Federation of Interventional and Therapeutic Neuroradiology in October 2017 in Budapest, Hungary. This multi-society meeting was dedicated to establish standards of practice in acute ischemic stroke ...
Source: The Canadian Journal of Neurological Sciences - March 20, 2019 Category: Neurology Authors: Pierot L, Jarayaman M, Szikora I, Hirsch J, Baxter B, Miyachi S, Mahadevan J, Chong W, Mitchell PJ, Coulthard A, Rowley HA, Sanelli PC, Tampieri D, Brouwer P, Fiehler J, Kocer N, Vilela P, Rovira A, Fischer U, Caso V, van der Wort B, Sakai N, Matsumaru Y, Tags: Can J Neurol Sci Source Type: research

Uric Acid Levels Correlate with Sensory Nerve Function in Healthy Subjects.
CONCLUSION: Higher UA levels correlate with lower sensory nerve function in healthy subjects, expanding the evidence of possible negative influence of UA on peripheral nerves, although a causative role has not yet established. PMID: 30880660 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - March 18, 2019 Category: Neurology Authors: Abraham A, Katzberg HD, Lovblom LE, Perkins BA, Bril V Tags: Can J Neurol Sci Source Type: research

Clot Histopathology in Ischemic Stroke with Infective Endocarditis.
CONCLUSION: Detailed morphological and histopathological analysis of EVT-retrieved clots including Gram staining can assist in etiological classification of the clot. Understanding the composition of the clot may be of clinical value in early diagnostics and mapping treatment planning in IE. PMID: 30867075 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - March 14, 2019 Category: Neurology Authors: Bhaskar S, Saab J, Cappelen-Smith C, Killingsworth M, Wu XJ, Cheung A, Manning N, Aouad P, McDougall A, Hodgkinson S, Cordato D Tags: Can J Neurol Sci Source Type: research

Intraoperative Flash Visual Evoked Potential Recording and Relationship to Visual Outcome.
CONCLUSIONS: Our FVEP findings relate to visual outcome with a sensitivity and specificity of 1.0. New methods for rapidly acquiring reproducible FVEP waveforms allowed for timely reporting of significant FVEP change resulting in prompt surgical action. This may have accounted for the low postoperative visual deficit rate (1%) in this series. PMID: 30867080 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - March 14, 2019 Category: Neurology Authors: Houlden DA, Turgeon CA, Amyot NS, Edem I, Sinclair J, Agbi C, Polis T, Alkherayf F Tags: Can J Neurol Sci Source Type: research

Cerebral Venous Sinus Thrombosis in Mid-South USA.
PMID: 30829186 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - March 4, 2019 Category: Neurology Authors: Musee J, Kumar AB Tags: Can J Neurol Sci Source Type: research

Cholinergic Neurons in Nucleus Subputaminalis in Primary Progressive Aphasia.
CONCLUSION: Regardless of underlying pathology, all cases presenting with PPA showed a marked loss of cholinergic neurons in the NSP, providing further evidence for the importance of this nucleus in language function. PMID: 30819267 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - March 1, 2019 Category: Neurology Authors: Hamodat H, Fisk JD, Darvesh S Tags: Can J Neurol Sci Source Type: research

Living with Migraine in Canada - A National Community-Based Study.
CONCLUSIONS: In this Canadian sample, migraine was associated with worse health-related variables in men compared with women. However, both men and women were significantly affected by migraine across various health-related variables. Thus, it is important to improve clinical and public health interventions addressing the impact of migraine across individuals of all ages, sexes, and sociodemographic backgrounds. PMID: 30816083 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - February 28, 2019 Category: Neurology Authors: Altura KC, Patten SB, Williams JVA, Fiest KM, Jetté N Tags: Can J Neurol Sci Source Type: research

The 2018 ter Brugge Lecture: Problems with the Introduction of Innovations in Neurovascular Care.
Abstract Most endovascular innovations have been introduced into clinical care by showing good outcomes in small enthusiastic case series of selected patients. Randomized clinical trials (RCTs) have rarely been performed, except for acute ischemic stroke, but even then most trial designs were too explanatory to inform clinical decisions. In this article, we review 2 × 2 tables and forest plots that summarize RCT results to examine methodological issues in the design and interpretation of clinical studies. Research results can apply in practice when RCTs are all-inclusive, pragmatic trials. Common p...
Source: The Canadian Journal of Neurological Sciences - February 21, 2019 Category: Neurology Authors: Raymond J, Fahed R, Roy D, Darsaut TE Tags: Can J Neurol Sci Source Type: research

Vitamins and Minerals for Migraine Prophylaxis: A Systematic Review and Meta-analysis.
CONCLUSIONS: Based on insufficient evidence, it is unknown if coenzyme Q10 and magnesium are effective for migraine prophylaxis in adults. High-quality, adequately powered RCTs are needed to fully evaluate the efficacy and safety of vitamins and minerals for migraine prophylaxis. PMID: 30764890 [PubMed - as supplied by publisher] (Source: The Canadian Journal of Neurological Sciences)
Source: The Canadian Journal of Neurological Sciences - February 15, 2019 Category: Neurology Authors: Okoli GN, Rabbani R, Kashani HH, Wierzbowski AK, Neilson C, Mansouri B, Zarychanski R, Abou-Setta AM Tags: Can J Neurol Sci Source Type: research