Proximal humeral fractures in children - controversies in decision making
ConclusionsFirstly, there is a need for consensus among experts on how fracture angulation in PHFs in children should be reliably determined. Our data indicate that choosing one method everybody agrees to use could be more helpful than using the most sophisticated. However, the overall importance of fracture angulation should also be critically discussed. Finally, experts should agree on treatment algorithms that could translate into guidelines to standardize the care and perform reliable outcome studies.Level of evidenceIII. (Source: European Journal of Trauma and Emergency Surgery)
Source: European Journal of Trauma and Emergency Surgery - April 30, 2024 Category: Emergency Medicine Source Type: research

Unlocking the key to increasing survival from out-of-hospital cardiac arrest – 24/7 accessible AEDs
To the Editor, (Source: Resuscitation)
Source: Resuscitation - April 30, 2024 Category: Emergency Medicine Authors: Greg Page, Janet Bray Tags: Letter to the Editor Source Type: research

Considering Adverse Effects of Common Antihypertensive Medications in the ED
AbstractPurpose of ReviewTo evaluate the adverse effects of common antihypertensive agents utilized or encountered in the Emergency Department.Recent FindingsAll categories of antihypertensive agents may manifest adverse effects, inclusive of adverse drug reactions (ADRs), drug-to-drug interactions, or accidental overdose. Adverse effects, and specifically ADRs, may be stratified into the organ systems affected, might require specific time-sensitive interventions, could pose particular risks to vulnerable populations, and may result in significant morbidity, and potential mortality.SummaryAdverse effects of common antihype...
Source: Current Hypertension Reports - April 30, 2024 Category: Primary Care Source Type: research

Analysis of outcomes and prognostic factor in acute type A aortic dissection complicated with preoperative shock: A single-center study
by Chun-Yu Lin, Ming-Chang Kao, Hsin-Fu Lee, Meng-Yu Wu, Chi-Nan Tseng BackgroundAcute type A aortic dissection (ATAAD) is a critical cardiovascular emergency that requires prompt surgical intervention for preserving life, particularly in patients with critical preoperative status. This retrospective study aimed to investigate the clinical features, early and late outcomes, and prognostic factors in patients undergoing aortic repair surgery for ATAAD complicated with preoperative shock. MethodsBetween April 2007 and July 2020, 694 consecutive patients underwent emergency ATAAD repair at our institution, including 162 (23.3...
Source: PLoS One - April 30, 2024 Category: Biomedical Science Authors: Chun-Yu Lin Source Type: research

Sensors, Vol. 24, Pages 2871: Smart Water Quality Monitoring with IoT Wireless Sensor Networks
ngo Traditional laboratory-based water quality monitoring and testing approaches are soon to be outdated, mainly because of the need for real-time feedback and immediate responses to emergencies. The more recent wireless sensor network (WSN)-based techniques are evolving to alleviate the problems of monitoring, coverage, and energy management, among others. The inclusion of the Internet of Things (IoT) in WSN techniques can further lead to their improvement in delivering, in real time, effective and efficient water-monitoring systems, reaping from the benefits of IoT wireless systems. However, they still suffer from th...
Source: Sensors - April 30, 2024 Category: Biotechnology Authors: Yurav Singh Tom Walingo Tags: Article Source Type: research

Clinical care pathway and management of major bleeding associated with non-vitamin k antagonist oral anticoagulants: a modified delphi consensus from saudi arabia and uae
Conclusion: The present Delphi consensus provides evidence-based recommendations and protocols for the management of NOAC-associated bleeding in the region. Patients with major NOAC-induced bleeding should be referred to a well-equipped ED with standardized management protocols. A multidisciplinary approach is recommended for establishing the association between NOAC use and major bleeding. Treating physicians should have prompt access to specific reversal agents to optimize patient outcomes. Real-world evidence and national guidelines are needed to aid all stakeholders involved in NOAC-induced bleeding management. (Source...
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 30, 2024 Category: Hematology Authors: Abdulrahman Al Raizah, Fakhr Alayoubi, Galal Hassan Abdelnaby, Hazzaa Alzahrani, Majid Farraj Bakheet, Mohammed A Alskaini, Rasha Buhumaid, Sameer Al Awadhi, Sara Nooruddin Kazim, Thiagarajan Jaiganesh, Zohair Al Asiri Source Type: research

Agreement between three noninvasive temperature monitoring devices during spinal anaesthesia for caesarean delivery: a prospective observational study
This study aimed to compare a noninvasive core temperature monitor with two readily available peripheral temperature monitors during obstetric spinal anaesthesia. We undertook a prospective observational study including elective and emergency caesarean deliveries, to determine the agreement between affordable reusable surface temperature monitors (Welch Allyn SureTemp ® Plus oral thermometer and the Braun 3-in-1 No Touch infrared thermometer) and the Dräger T-core© (using dual-sensor heat flux technology), in detecting thermoregulatory changes during obstetric spinal anaesthesia. Predetermined clinically relevant limits...
Source: Journal of Clinical Monitoring and Computing - April 30, 2024 Category: Information Technology Source Type: research

Young Adults Often Know Signs of Opioid Overdose, but Not How To Give Naloxone
A majority of young adults can correctly identify at least one sign of opioid overdose, but relatively few know how to administer naloxone, astudy inJAMA Pediatrics has found.Christina E. Freibott, M.P.H., of the Boston University School of Public Health and colleagues examined data from 7,071 young adults aged 18 to 25 attending an institution of higher learning who participated in the 2021-2022Healthy Minds study. The participants answered four questions adapted from the Opioid Overdose Knowledge Scale and the Opioid Overdose Attitudes Scale about the following:What naloxone is used for.What the signs of opioid overdose ...
Source: Psychiatr News - April 29, 2024 Category: Psychiatry Tags: Alaska Native college emergency services gender identity Healthy Minds Study naloxone opioids overdose Pacific Islander university young adults Source Type: research

Nitrous oxide-induced myeloneuropathy in a Thai adolescent: a case report
Paediatr Int Child Health. 2024 Apr 29:1-4. doi: 10.1080/20469047.2024.2344403. Online ahead of print.ABSTRACTNitrous oxide, an inhalational anaesthetic, is popular with adolescents worldwide as an accessible recreational drug which induces a euphoric effect. However, chronic abuse leads to serious complications such as myeloneuropathy and bone marrow suppression by inactivation of vitamin B12. A 17-year-old girl presented with nitrous oxide-induced myeloneuropathy. She reported chronic nitrous oxide inhalation for 10 months and was admitted to the emergency department on account of repeated falls for 2 weeks. She also had...
Source: Paediatrics and international child health - April 29, 2024 Category: Pediatrics Authors: S Puetpaiboon M Meepolprapai P Saengpanit P Laohathai W Prasertsup S Khiewbanyang R Charupash O Sanmaneechai Worapant Kriengsoontornkij Source Type: research

Association between opioid use disorder and palliative care: a cohort study using linked health administrative data in Ontario, Canada
CMAJ. 2024 Apr 28;196(16):E547-E557. doi: 10.1503/cmaj.231419.ABSTRACTBACKGROUND: People with opioid use disorder (OUD) are at risk of premature death and can benefit from palliative care. We sought to compare palliative care provision for decedents with and without OUD.METHODS: We conducted a cohort study using health administrative databases in Ontario, Canada, to identify people who died between July 1, 2015, and Dec. 31, 2021. The exposure was OUD, defined as having emergency department visits, hospital admissions, or pharmacologic treatments suggestive of OUD within 3 years of death. Our primary outcome was receipt of...
Source: Canadian Medical Association Journal - April 29, 2024 Category: General Medicine Authors: Jenny Lau Mary M Scott Karl Everett Tara Gomes Peter Tanuseputro Sheila Jennings Rebecca Bagnarol Camilla Zimmermann Sarina R Isenberg Source Type: research

Medicinal chemistry strategies toward broad-spectrum antiviral agents to prevent next pandemics
Eur J Med Chem. 2024 Apr 25;271:116442. doi: 10.1016/j.ejmech.2024.116442. Online ahead of print.ABSTRACTThe pandemic and tremendous impact of severe acute respiratory syndrome coronavirus 2 alert us, despite great achievements in prevention and control of infectious diseases, we still lack universal and powerful antiviral strategies to rapidly respond to the potential threat of serious infectious disease. Various highly contagious and pathogenic viruses, as well as other unknown viruses may appear or reappear in human society at any time, causing a catastrophic epidemic. Developing broad-spectrum antiviral drugs with high...
Source: European Journal of Medicinal Chemistry - April 29, 2024 Category: Chemistry Authors: Zirui L ü Xiandong Dai Jianjie Xu Zhenming Liu Yongbiao Guo Zhenhua Gao Fanhua Meng Source Type: research

The health economic-industrial complex: production and innovation for universal health access, Brazil
Bull World Health Organ. 2024 May 1;102(5):352-356. doi: 10.2471/BLT.23.290838. Epub 2024 Apr 17.ABSTRACTPROBLEM: The coronavirus disease 2019 (COVID-19) pandemic has highlighted global disparities in accessing essential health products, demonstrating the critical need for low- and middle-income countries to develop local production and innovation capabilities.APPROACH: The health economic-industrial complex approach changed the values that guided innovation and industrial policies in Brazil. The approach directed health production and innovation to universal access; the health ministry led a whole-of-government approach; ...
Source: Bulletin of the World Health Organization - April 29, 2024 Category: International Medicine & Public Health Authors: Carlos Ag Gadelha Gabriela Maretto Marco Ac Nascimento Felipe Kamia Source Type: research

Resuscitation Update - What's New?
Anasthesiol Intensivmed Notfallmed Schmerzther. 2024 Apr;59(4):214-225. doi: 10.1055/a-2082-8685. Epub 2024 Apr 29.ABSTRACTPerfect, uninterrupted basic life support (BLS) is the key for successful cardiopulmonary resuscitation (CPR) in out-of-hospital cardiac arrest (OHCA). Time plays an important role in the treatment of OHCA. This applies both to the time until the start of BLS and the reduction of all pauses during resuscitation, especially chest compressions. In 2022, the rate of bystander-CPR showed an absolute increase of 4% compared to previous years. The bystander-CPR rate is currently above 50%. Compared to OHCA i...
Source: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS - April 29, 2024 Category: Intensive Care Authors: Jan-Thorsten Gr äsner Stephan Katzenschlager Leonie Hannappel Jan Wnent Source Type: research

Giraffes and Zebras on the Runway: the AMREF Flying Doctors (AFD) of Africa
This article follows a volunteer doctor and the author on the exciting journey to the Flying Doctors of Africa, based at Wilson Airport/Nairobi who reach out to a patient in medical needs from a rural airstrip within the Maasai Mara on which wild animals roam to medical evacuations which can span the entire globe.PMID:38684161 | DOI:10.1055/a-2148-3336 (Source: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS)
Source: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS - April 29, 2024 Category: Intensive Care Authors: Malte Sebastian Struckmeyer Source Type: research

Evaluating the impact of  the Community Helpers Program on adolescents 12-18 years old in Edmonton, Canada
CONCLUSION: Findings show contextual effect of CHP; i.e., being potentially exposed to the program reduced the likelihood of anxiety- and depression-related visits. Costs of CHP implementation could be compared with the avoided costs to assess economic benefits of implementing CHP.PMID:38683287 | DOI:10.17269/s41997-024-00878-6 (Source: Canadian Journal of Public Health)
Source: Canadian Journal of Public Health - April 29, 2024 Category: International Medicine & Public Health Authors: Mohammad Habibullah Pulok Arthur Novaes de Amorim Sandra Johansen Kristin Pilon Christina Lucente Vineet Saini Source Type: research