A systematic review of the impact of emergency medical service practitioner experience and exposure to out of hospital cardiac arrest on patient outcomes
To conduct a systematic review to evaluate the impact of emergency medical service (EMS) practitioner ’s years of career experience and exposure to out-of-hospital cardiac arrest (OHCA) on patient outcomes. (Source: Resuscitation)
Source: Resuscitation - August 4, 2020 Category: Emergency Medicine Authors: Janet Bray, Ziad Nehme, Andrew Nguyen, Andrew Lockey, Judith Finn, on behalf of the Education, Implementation, Teams Task Force of the International Liaison Committee on Resuscitation Tags: Review Source Type: research

Evidence-based crisis standards of care for out-of-hospital cardiac arrests in a pandemic
Pandemics such as COVID-19 can lead to severe shortages in healthcare resources, requiring the development of evidence-based Crisis Standard of Care (CSC) protocols. A protocol that limits the resuscitation of out-of-hospital cardiac arrests (OHCA) to events that are more likely to result in a positive outcome can lower hospital burdens and reduce emergency medical services resources and infection risk, although it would come at the cost of lives lost that could otherwise be saved. Our primary objective was to evaluate candidate OHCA CSC protocols involving known predictors of survival and identify the protocol that result...
Source: Resuscitation - August 3, 2020 Category: Emergency Medicine Authors: Peter Natalzia, William Murk, Jeffrey J. Thompson, Maia Dorsett, Jeremy T. Cushman, Philip Reed, Brian M. Clemency, the CARES Surveillance Group Tags: Clinical paper Source Type: research

‘There’s a hole in my bucket’: ‘No-flow’, ‘low-flow’, and resuscitative calculus
Earliest known archetype of the children ’s song, “There’s a Hole in My Bucket” Bergliederbüchlein (c 1700) (Source: Resuscitation)
Source: Resuscitation - August 2, 2020 Category: Emergency Medicine Authors: Joshua C. Reynolds Tags: Editorial Source Type: research

Prognostic value of repeated thromboelastography measurement for favorable neurologic outcome during targeted temperature management in out-of-hospital cardiac arrest survivors
Cardiac arrest can activate blood coagulation, which clinically manifests as obstruction of the microcirculation and multiple organ dysfunction. Thromboelastography (TEG) provides a rapid and comprehensive assessment of hemostatic processes, but there are limited data on the use of sequential TEG values during targeted temperature management (TTM) in out-of-hospital cardiac arrest (OHCA) survivors. The aim of this study was to investigate the prognostic value of coagulopathy assessed by repeated TEG to predict neurologically intact survival. (Source: Resuscitation)
Source: Resuscitation - August 2, 2020 Category: Emergency Medicine Authors: Gina Yu, Youn-Jung Kim, June-sung Kim, Sang-Il Kim, Seung Mok Ryoo, Shin Ahn, Won Young Kim Source Type: research

The optimal surface for delivery of CPR: a systematic review and meta-analysis
To determine the effect of CPR delivery surface (e.g. firm mattress, floor, backboard) on patient outcomes and CPR delivery. (Source: Resuscitation)
Source: Resuscitation - August 2, 2020 Category: Emergency Medicine Authors: Josephine Holt, Abigail Ward, Tay-Yibah Mohamed, Priya Chukowry, Natalia Grolmusova, Keith Couper, Peter Morley, Gavin D. Perkins Source Type: research

Cardiogenic shock and cardiac arrest complicating ST-segment elevation myocardial infarction in the United States, 2000 –2017
There are limited data on the outcomes of cardiogenic shock (CS) and cardiac arrest (CA) complicating ST-segment-elevation myocardial infarction (STEMI). (Source: Resuscitation)
Source: Resuscitation - August 2, 2020 Category: Emergency Medicine Authors: Saraschandra Vallabhajosyula, Shannon M. Dunlay, Abhiram Prasad, Lindsey R. Sangaralingham, Kianoush Kashani, Nilay D. Shah, Jacob C. Jentzer Tags: Clinical paper Source Type: research

Effects of real-time feedback on cardiopulmonary resuscitation quality on outcomes in adult patients with cardiac arrest: A systematic review and meta-analysis
To investigate the relationship between the implementation of real-time audiovisual cardiopulmonary resuscitation (CPR) feedback devices with cardiac arrest patient outcomes, such as return of spontaneous circulation (ROSC), short-term survival, and neurological outcome. (Source: Resuscitation)
Source: Resuscitation - August 2, 2020 Category: Emergency Medicine Authors: Shao-An Wang, Chan-Ping Su, Hsien-Yu Fan, Wen-Hsuan Hou, Yang-Ching Chen Tags: Review Source Type: research

Analysis of prehospital perimortem caesarean deliveries performed by Helicopter Emergency Medical Services in The Netherlands and recommendations for the future
In this study, we aimed to examine all PCDs performed by the four Helicopter Emergency Medical Services in the Netherlands; to describe the procedures, outcomes, complications, and compliance with the recommended guidelines; and to formulate recommendations. (Source: Resuscitation)
Source: Resuscitation - July 31, 2020 Category: Emergency Medicine Authors: XRJ Moors, TH Biesheuvel, J Cornette, MG Van Vledder, A Veen, M de Quelerij, EEM Weelink, JJ Duvekot Tags: Clinical paper Source Type: research

Editorial Board
(Source: Resuscitation)
Source: Resuscitation - July 25, 2020 Category: Emergency Medicine Source Type: research

Implementation of the Los Angeles Tiered Dispatch System is Associated with an Increase in Telecommunicator-Assisted CPR
The objective of this study was to assess the impact of this new dispatch system on telecommunicator-assisted CPR (T-CPR). (Source: Resuscitation)
Source: Resuscitation - July 25, 2020 Category: Emergency Medicine Authors: Stephen Sanko, Saman Kashani, Christianne Lane, Marc Eckstein Tags: Clinical paper Source Type: research

Sustained inflation with 21% versus 100% oxygen during cardiopulmonary resuscitation of asphyxiated newborn piglets - A randomized controlled animal study
Current neonatal resuscitation guidelines recommend using 100% oxygen during chest compressions (CC), however the most effective oxygen concentration during cardiopulmonary resuscitation remains controversial. (Source: Resuscitation)
Source: Resuscitation - July 23, 2020 Category: Emergency Medicine Authors: Catalina Garcia Hidalgo, Anne L. Solevag, Seung Yeun Kim, Gyu Hong Shim, Po-Yin Cheung, Tze-Fun Lee, Megan O ’Reilly, Georg M. Schmölzer Tags: Experimental paper Source Type: research

Optimal combination of clinical examinations for neurologic prognostication of out-of-hospital cardiac arrest patients
Targeted temperature management (TTM) may alter the results of clinical examination and delay motor response recovery; hence, re-establishing the accuracy and optimal timing of performing clinical examinations are crucial. Therefore, we aimed to identify the optimal combination and timing of clinical examinations for predicting the neurologic outcomes in patients undergoing TTM. (Source: Resuscitation)
Source: Resuscitation - July 22, 2020 Category: Emergency Medicine Authors: Ji Hoon Kim, Incheol Park, Sung Phil Chung, Ha Yan Kim, In Kyung Min, Su Jin Kim, Soo Hyun Kim, Jae Hoon Lee, Hyung Jun Moon, Yoo Seok Park, on behalf of the Korean Hypothermia Network Investigators Tags: Clinical paper Source Type: research

Changes in the incidence of out-of-hospital cardiac arrest: Differences between cardiac and non-cardiac aetiologies
We aimed to assess temporal changes in the incidence of OHCAs of presumed cardiac and non-cardiac aetiologies. (Source: Resuscitation)
Source: Resuscitation - July 22, 2020 Category: Emergency Medicine Authors: Saeed Alqahtani, Ziad Nehme, Brett Williams, Stephen Bernard, Karen Smith Tags: Clinical paper Source Type: research

Reply to: Coronavirus disease 2019 and ethical considerations for extracorporeal cardiopulmonary resuscitation
We would like to thank Dr. Spyros D. Mentzelopoulos, Dr. Leo Bossaert, and Dr. Robert Greif, for showing interest in our article, entitled “Extracorporeal Cardiopulmonary Resuscitation Should Not Be Performed on Confirmed or Suspected COVID-19 Patients.”1 They have, however, expressed some concerns that we would like to address. (Source: Resuscitation)
Source: Resuscitation - July 21, 2020 Category: Emergency Medicine Authors: Kenji Kandori, Hiromichi Narumiya, Ryoji Iizuka Tags: Letter to the Editor Source Type: research

What gaps in chest compressions tell us about gaps in CPR knowledge
Defining high quality CPR in quantitative terms, as well as determining the impact of high quality CPR on cardiac arrest outcomes, have proven to be daunting challenges over the past 15 years since the introduction of CPR-sensing technologies. 1,2 Use of these tools has allowed for the measurement of various CPR delivery metrics, including chest compression fraction (CCF).3 CCF is defined as the proportion of time performing chest compressions during a resuscitation episode while a patient is pulseless. (Source: Resuscitation)
Source: Resuscitation - July 21, 2020 Category: Emergency Medicine Authors: Charlotte F. Tisch, Benjamin S. Abella Tags: Editorial Source Type: research

Prone cardiopulmonary resuscitation: A scoping and expanded grey literature review for the COVID-19 pandemic
To identify and summarize the available science on prone resuscitation. To determine the value of undertaking a systematic review on this topic; and to identify knowledge gaps to aid future research, education and guidelines. (Source: Resuscitation)
Source: Resuscitation - July 21, 2020 Category: Emergency Medicine Authors: Matthew J. Douma, Ella Mackenzie, Tess Loch, Maria C. Tan, Dustin Anderson, Christopher Picard, Lazar Milovanovic, Domhnall O ’Dochartaigh, Peter G. Brindley Tags: Review Source Type: research

Adherence to guidelines is associated with improved survival following in-hospital cardiac arrest
Most Resuscitation guidelines have recommendations regarding maximum delay times from collapse to calling for the rescue team and initiation of treatment following cardiac arrest. The aim of the study was to investigate the association between adherence to guidelines for cardiopulmonary resuscitation (CPR) after in-hospital cardiac arrest (IHCA) and survival with a focus on delay to treatment. (Source: Resuscitation)
Source: Resuscitation - July 20, 2020 Category: Emergency Medicine Authors: Fredrik Hessulf, Johan Herlitz, Araz Rawshani, Solveig Aune, Johan Israelsson, Marie-Louise S ödersved–Källestedt, Per Nordberg, Peter Lundgren, Johan Engdahl Tags: Clinical paper Source Type: research

Outcomes of In-Hospital Cardiac Arrest in Patients with COVID-19 in New York City
Cardiopulmonary resuscitation (CPR) in patients with in-hospital cardiac arrest (IHCA) has been associated with poor overall survival and neurologic recovery.1 The coronavirus 2019 (COVID-19) global pandemic carries a high mortality rate with high risk of cardiopulmonary arrest.2 Clear policies for crisis standards of care and CPR are essential in light of limited Intensive Care Unit (ICU) resources and aerosolized transmission among code team members.3 There is limited literature regarding the survival outcomes and effectiveness of CPR in patients with COVID-19 who suffer cardiac arrest. (Source: Resuscitation)
Source: Resuscitation - July 20, 2020 Category: Emergency Medicine Authors: Vishad Sheth, Imran Chishti, Adam Rothman, Michael Redlener, John Liang, Di Pan, Joseph Mathew Tags: Letter to the Editor Source Type: research

Cardiac tamponade as a cause of cardiac arrest in severe COVID-19 pneumonia
Descriptive studies of patients with SARS-CoV-2 infection show that in addition to cardiovascular disease as a predisposing factor, the infection itself seems to trigger acute myocardial injury.1 Previous studies on MERS-CoV and SARS-CoV, with a similar pathogenic mechanism, already describe the development of myocardial damage in an infected patient and the complexity of managing them. (Source: Resuscitation)
Source: Resuscitation - July 20, 2020 Category: Emergency Medicine Authors: Juan Carlos Ruiz-Rodr íguez, Luis Chiscano Camón, Daniel Ruiz, Judit Sacanell Lacasa, Eduard Argudo Serra, Francesc Xavier Nuvials Casals, Ricard Ferrer Source Type: research

Coronavirus disease 2019 and ethical considerations for extracorporeal cardiopulmonary resuscitation
In their recent letter to the Editor, Drs. Kandori and colleagues suggest against using extracorporeal cardiopulmonary resuscitation (E-CPR) in cardiac arrest patients with confirmed or suspected coronavirus disease 2019 (COVID-19).1 They argue: (1) potential technical difficulties with E-CPR interventions during resuscitation (e.g. vessel cannulation) while wearing personal protective equipment (PPE); (2) communication problems associated with wearing N95 mask in a negative-pressure isolation room; (3) resuscitation team fears of contracting the disease and “immeasurable physical and emotional fatigue”; and (4...
Source: Resuscitation - July 20, 2020 Category: Emergency Medicine Authors: Spyros D. Mentzelopoulos, Leo Bossaert, Robert Greif Tags: Letter to the Editor Source Type: research

Survival and functional outcome at hospital discharge following in-hospital cardiac arrest (IHCA): A prospective multicentre observational study
To evaluate the functional outcome of patients after in-hospital cardiac arrest (IHCA) and to identify associations with good functional outcome at hospital discharge. (Source: Resuscitation)
Source: Resuscitation - July 19, 2020 Category: Emergency Medicine Authors: G. Pound, D. Jones, G.M. Eastwood, E. Paul, C.L. Hodgson, The ANZ-CODE Investigators Tags: Clinical paper Source Type: research

Suboptimal Rates of Return of Spontaneous Circulation with Prehospital CPR in the COVID-19 Era
The COVID-19 pandemic – caused by the virus SARS-COV-2 – has significantly taxed all levels of the modern healthcare system.1 The virulence of SARS-COV-2 has led to substantial increases in the usage of personal protective equipment – including masks, gowns, face shields, and gloves – in a variety of healthcare s ettings.2 Cardiopulmonary resuscitation (CPR) is one of the most important and lifesaving interventions performed by healthcare providers of all levels, and favorable outcomes are heavily contingent on proper form and performance based on published standards. (Source: Resuscitation)
Source: Resuscitation - July 16, 2020 Category: Emergency Medicine Authors: Aditya C. Shekhar, Christopher Mercer, Ira Blumen, Jagat Narula Tags: Letter to the Editor Source Type: research

Video of cardiopulmonary resuscitation induced consciousness during ventricular fibrillation
We report the experience of an emergency medical technician (EMT) who encountered CPRIC in an ambulance. (Source: Resuscitation)
Source: Resuscitation - July 16, 2020 Category: Emergency Medicine Authors: Kuan-Chen Chin, Shang-Chiao Yang, Wen-Chu Chiang Tags: Letter to the Editor Source Type: research

Data-driven classification of arrest location for emergency department cardiac arrests
Resuscitation research is inconsistent in how emergency department (ED) arrests are classified. We tested whether clinical features of ED arrests more closely resembled out-of-hospital cardiac arrest (OHCA) or in-hospital cardiac arrest (IHCA). (Source: Resuscitation)
Source: Resuscitation - July 13, 2020 Category: Emergency Medicine Authors: Nancy Mikati, Clifton Callaway, Patrick Coppler, Jonathan Elmer, on behalf of the University of Pittsburgh Post-Cardiac Arrest Service Tags: Short paper Source Type: research

Seizure-like presentation in OHCA creates barriers to dispatch recognition of cardiac arrest
This study aims to determine the impact of seizure-like activity among OHCA patients during 9-1-1 calls. (Source: Resuscitation)
Source: Resuscitation - July 12, 2020 Category: Emergency Medicine Authors: Madison Schwarzkoph, Lihua Yin, Lindsey Hergert, Christopher Drucker, Catherine R. Counts, Mickey Eisenberg Tags: Clinical paper Source Type: research

Echocardiographic evaluation of cardiac recovery after refractory out-of-hospital cardiac arrest
The mechanisms and degree of myocardial recovery during treatment with venoarterial extracorporeal membrane oxygenation (VA-ECMO) are unclear. We performed a descriptive study to evaluate myocardial recovery and changes in parameters of myocardial loading using echocardiography. (Source: Resuscitation)
Source: Resuscitation - July 12, 2020 Category: Emergency Medicine Authors: Rajat Kalra, Jason A. Bartos, Marinos Kosmopoulos, Claire Carlson, Ranjit John, Andrew Shaffer, Cindy Martin, Ganesh Raveendran, Demetris Yannopoulos Tags: Clinical paper Source Type: research

Regional cerebral saturation in post-cardiac arrest patients is doomed … or is it just a near death experience?
One of the most challenging aspects in the treatment of a post-cardiac arrest patient is the assessment of the extent of brain damage, and its concomitant prognosis. Clinicians are continuously confronted with the optimistic expectations of relatives. Parameters that provide early prognostic information are highly desirable in the post-cardiac arrest setting since they would facilitate communication with relatives and would allow better triage of economically burdensome therapies. Reliable, practical measures of intra- and post-arrest neurologic function have potential to guide treatment geared toward reducing neurological...
Source: Resuscitation - July 12, 2020 Category: Emergency Medicine Authors: Ward Eertmans, David Salcido, Cornelia Genbrugge Tags: Editorial Source Type: research

Auditory evoked responses have limited utility after cardiac arrest
Recovery of both brainstem and cortical function are necessary for awakening from coma after cardiac arrest.1 Early post-arrest risk stratification and neurological prognostication focuses on assessment of the brainstem. The brainstem is more resistant to hypoxic-ischemic injury,2 so persistent dysfunction implies severe global brain injury and thus is a specific predictor of poor outcome.3 Among patients who awaken, recovery of brainstem function typically precedes that of the more complex cortical function, making it a useful early indicator of recovery potential. (Source: Resuscitation)
Source: Resuscitation - July 11, 2020 Category: Emergency Medicine Authors: Jonathan Elmer, Alexis Steinberg Tags: Editorial Source Type: research

Reply to: Taipei Azalea: Another example of “MacGyver bias” during COVID-19 pandemic?
We thank Leong et al for evaluating our design and listing several concerns which we had also discussed and worth sharing here.1 (Source: Resuscitation)
Source: Resuscitation - July 11, 2020 Category: Emergency Medicine Authors: Wen-Shuo Yang, Bin-Chou Lee, Wen-Chu Chiang, Yu-Chun Chien, Shey-Ying Chen, Matthew Huei-Ming Ma, Sheng-Wen Hou Tags: Letter to the Editor Source Type: research

Contributing Factors to Early Recurrence of Ventricular Fibrillation during Out-of-hospital Cardiac Arrest: an Observational Retrospective Study
In out-of-hospital cardiac arrest (OHCA), external electric shock (EES) is recommended for treating ventricular fibrillation (VF). Refibrillation commonly occurs within one minute post-shock. We aimed to investigate refibrillation times and identifyclinical and electrical factors associated with them. (Source: Resuscitation)
Source: Resuscitation - July 9, 2020 Category: Emergency Medicine Authors: Daniel Jost, Vivien Hong Tuan Ha, Julie Trichereau, Benoit Frattini, Cl ément Derkenne, Sabine Lemoine, Frédéric Lemoine, Romain Jouffroy, Romain Kedzierewicz, Frédérique Briche, Pascal Diegelmann, René Bihannic, Olivier Stibbe, Bertrand Prunet, on Tags: Clinical paper Source Type: research

Intra-arrest transoesophageal echocardiographic findings and resuscitation outcomes
The relationship between echocardiographic findings of intra-arrest TEE and resuscitation outcomes was not clearly identified. We assessed echocardiographic findings observed in intra-arrest TEE and its relationship with resuscitation outcomes. (Source: Resuscitation)
Source: Resuscitation - July 9, 2020 Category: Emergency Medicine Authors: Woo Jin Jung, Kyoung-Chul Cha, Yong Won Kim, Yoon Seop Kim, Young-Il Roh, Sun Ju Kim, Hye Sim Kim, Sung Oh Hwang Tags: Clinical paper Source Type: research

Maximizing Computed Tomography in Assessing Neurological Prognosis After Cardiac Arrest
With cardiac arrest (CA) the lack of brain circulation soon leads to energy failure in neurons, anoxic-ischemic encephalopathy (AIE). The decreased function of the ATP-driven sodium-potassium pump soon leads to ionic/cytotoxic edema1, which is detected on CT as swelling of grey matter structures and on MRI as increased signal on diffusion-weighted imaging and decreased apparent diffusion coefficient2 Various parts of the brain show different susceptibility and speed of evolution of neuronal swelling and death; thus timing of imaging is potentially important. (Source: Resuscitation)
Source: Resuscitation - July 8, 2020 Category: Emergency Medicine Authors: G. Bryan Young Tags: Editorial Source Type: research

Characteristics and Outcomes of Cardiac Arrest Survivors with Acute Pulmonary Embolism
The characteristics and outcomes of patients that suffer cardiac arrest due to acute pulmonary embolism (PE) are not well studied. We compared the characteristics and outcomes of cardiac arrest survivors that suffered PE with other forms of cardiac arrest. (Source: Resuscitation)
Source: Resuscitation - July 8, 2020 Category: Emergency Medicine Authors: Abhishek Dutta, Bhupendar Tayal, Kristian Hay Kragholm, Youssef Masmoudi, John Azizian, Lawson Mcdonald, Amandeep Goyal, Peter Sogaard, Waqas T. Qureshi Tags: Clinical paper Source Type: research

Out-of-hospital cardiac arrest during the COVID-19 pandemic in the Province of Padua, Northeast Italy
Authors from Lombardy, Italy 1, and Paris, France 2 have recently reported an increase in the incidence of out-of-hospital cardiac arrest (OHCA), suggesting a direct or indirect effect of COVID-19. As hypothesized 3, fewer patients received bystander-initiated cardiopulmonary resuscitation (CPR), and emergency medical services (EMS) arrival time and mortality were higher in both studies. In contrast, OHCA incidence and bystander-CPR in King County, USA remained similar to that of previous years 4. (Source: Resuscitation)
Source: Resuscitation - July 8, 2020 Category: Emergency Medicine Authors: Andrea Paoli, Laura Brischigliaro, Tommaso Scquizzato, Andrea Favaretto, Andrea Spagna Tags: Letter to the Editor Source Type: research

Brain MR imaging and spectroscopy for outcome prognostication after pediatric cardiac arrest
Children surviving cardiac arrest are at high risk of neurological morbidity and mortality; however, there is a lack of validated prognostic biomarkers. We aimed to evaluate brain magnetic resonance imaging (MRI) and spectroscopy (MRS) as predictors of death and disability. Secondly, we evaluated whether MRI/S by randomized group. (Source: Resuscitation)
Source: Resuscitation - July 8, 2020 Category: Emergency Medicine Authors: Ericka L. Fink, Jessica Wisnowski, Robert Clark, Rachel P. Berger, Anthony Fabio, Andre Furtado, Srikala Narayan, Derek C. Angus, R. Scott Watson, Chunyan Wang, Clifton W. Callaway, Michael J. Bell, Patrick M. Kochanek, Stefan Bluml, Ashok Panigrahy Tags: Clinical paper Source Type: research

Damaged: Elevated GFAP and UCH-L1 as the Black Flag of Brain Injury
Despite recent advances in neurologic prognostication after cardiac arrest, particularly using neuroimaging and fluid-based biomarkers, there remains a persistent need for objective, accurate indicators of long-term prognosis. In this issue of Resuscitation, Ebner and colleagues evaluated the utility of serum biomarkers glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase-L1 (UCH-L1) for prediction of 6-month neurologic outcome after out of hospital cardiac arrest (OHCA) as measured by the Cerebral Performance Scale (CPC) [cite current paper]. (Source: Resuscitation)
Source: Resuscitation - July 8, 2020 Category: Emergency Medicine Authors: Holly E. Hinson, Taylor N. Anderson Tags: Editorial Source Type: research

Taipei Azalea: Another example of “MacGyver bias” during COVID-19 pandemic?
Yang et al described an airway device modification for use in emergency medical services (EMS) named the Taipei Azalea.1 It is made by modifying an i-gel ® supraglottic airway (SGA) to include a breathing barrier (referred to as a face shield by Yang), along with pre-attached securing tape, and a Heat& Moisture Exchanging Filter (HMEF). However, we are cautious about the inherent risks of using a “MacGyver device” that is not scientifically tested.2 No data regarding the risk reduction of exposure to respiratory aerosols nor the clinical practicality of the device is presented. (Source: Resuscitation)
Source: Resuscitation - July 8, 2020 Category: Emergency Medicine Authors: Yuen Chin Leong, Sheldon Cheskes, Ron G. Latchmansingh, Jason E. Buick, Ian R. Drennan, P. Richard Verbeek Tags: Letter to the Editor Source Type: research

Effects of different adrenaline doses on cerebral oxygenation and cerebral metabolism during cardiopulmonary resuscitation in pigs
The influence of adrenaline during cardiopulmonary resuscitation (CPR) on the neurological outcome of cardiac arrest survivors is unclear. As little is known about the pathophysiological effects of adrenaline on cerebral oxygen delivery and cerebral metabolism we investigated its effects on parameters of cerebral oxygenation and cerebral metabolism in a pig model of CPR. (Source: Resuscitation)
Source: Resuscitation - July 8, 2020 Category: Emergency Medicine Authors: Gabriel Putzer, Judith Martini, Patrick Spraider, Rouven Hornung, Daniel Pinggera, Julia Abram, Niklas Altaner, Tobias Hell, Bernhard Glodny, Raimund Helbok, Peter Mair Tags: Experimental paper Source Type: research

Out-of-hospital cardiac arrest and donation after circulatory death during the covid-19 pandemia
The rapid emergence of the novel coronavirus (COVID) disease posed potential obstacle for organ procurement and transplantation worldwide and in European countries.1 (Source: Resuscitation)
Source: Resuscitation - July 5, 2020 Category: Emergency Medicine Authors: Chiara Lazzeri, Davide Ghinolfi, Vincenzo Li Marzi, Sergio Serni, Paolo De Simone, Federico Franchi, Luca Luzzi, Sabino Scolletta, Adriano Peris Tags: Letter to the Editor Source Type: research

Postcardiac arrest neurological prognostication with quantitative regional cerebral densitometry
To quantitatively assess the severity of anoxic-ischemic brain injury early after cardiac arrest (CA) using a novel automated method applied to head computed tomography (HCT). (Source: Resuscitation)
Source: Resuscitation - July 3, 2020 Category: Emergency Medicine Authors: Yousef Hannawi, John Muschelli, Maximilian Mulder, Matthew Sharrock, Christian Storm, Christoph Leithner, Ciprian M. Crainiceanu, Robert D. Stevens Tags: Clinical paper Source Type: research

Early-onset pneumonia following bag-mask ventilation versus endotracheal intubation during cardiopulmonary resuscitation: A substudy of the CAAM trial
Early-onset pneumonia (EOP) is a common in-hospital complication in survivors of out-of-hospital cardiac arrest. In this substudy of the CAAM trial, we aimed to compare whether bag mask ventilation (BMV) compared to endotracheal intubation (ETI) performed during cardiopulmonary resuscitation increases the risk of developing EOP. (Source: Resuscitation)
Source: Resuscitation - July 3, 2020 Category: Emergency Medicine Authors: Josefine S. Baekgaard, Mohamed N. Triba, Morgane Brandeis, Jacob Steinmetz, Yves Cohen, Judith Gorlicki, Lars S. Rasmussen, Sandrine Deltour, Fr édéric Lapostolle, Frédéric Adnet Tags: Clinical paper Source Type: research

Immediate coronary angiogram in out-of-hospital cardiac arrest patients with non-shockable initial rhythm and without ST-segment elevation - is there a clinical benefit?
Coronary angiogram (CA) may be useful after resuscitated out-of-hospital cardiac arrest (OHCA), but data regarding its benefit in patients with non-shockable initial rhythm without ST-segment elevation is scarce. We aimed to evaluate the prevalence of acute coronary syndrome (ACS) and survival in OHCA patients with non-shockable initial rhythm without ST-segment elevation and compare them to patients with shockable initial rhythm without ST-segment elevation. (Source: Resuscitation)
Source: Resuscitation - July 2, 2020 Category: Emergency Medicine Authors: Sebastian Voicu, Vilhelmas Bajoras, Emmanuel Gall, Nicolas Deye, Isabelle Malissin, Jean-Guillaume Dillinger, Chakib Benajiba, Damien Logeart, Patrick Henry, Bruno Megarbane, Georgios Sideris Tags: Clinical paper Source Type: research

Comparison of an early warning score to single-triggering warning system for inpatient deterioration: An audit of 4089 medical emergency calls
Various studies have compared different track and trigger systems for their ability to identify patients at risk of deterioration,1 however, an optimal system is yet to emerge.2 The aim of this study was to compare a multi-parameter track and trigger system (Modified Early Warning Score [MEWS]), used in the Australian Capital Territory (ACT),3 with a single-parameter track and trigger system ( “Between the Flags” [BTF]) used in New South Wales (NSW)4 and assess their timeliness in detecting patient deterioration 24 hours prior to a Medical Emergency Team (MET) activation. (Source: Resuscitation)
Source: Resuscitation - July 2, 2020 Category: Emergency Medicine Authors: Ahmed Khalaf, Zsuzsoka Kecskes, Ekavi N. Georgousopoulou, Imogen A. Mitchell Tags: Letter to the Editor Source Type: research

The impact of ventilation rate on end-tidal carbon dioxide level during manual cardiopulmonary resuscitation
Ventilation rate is a confounding factor for interpretation of end-tidal carbon dioxide (ETCO2) during cardiopulmonary resuscitation (CPR). The aim of our study was to to model the effect of ventilation rate on ETCO2 during manual CPR in adult out-of-hospital cardiac arrest (OHCA). (Source: Resuscitation)
Source: Resuscitation - July 1, 2020 Category: Emergency Medicine Authors: Sof ía Ruiz de Gauna, Jose Julio Gutiérrez, Jesus Ruiz, Mikel Leturiondo, Izaskun Azcarate, Digna María González-Otero, Carlos Corcuera, James Knox Russell, Mohamud Ramzan Daya Tags: < ![CDATA[Clinical paper]] > Source Type: research

Association between Time of Day and CPR Quality as Measured by CPR Hemodynamics during Pediatric In-hospital CPR
Patients who suffer in-hospital cardiac arrest (IHCA) are less likely to survive if the arrest occurs during nighttime versus daytime. Diastolic blood pressure (DBP) as a measure of chest compression quality was associated with survival from pediatric IHCA. We hypothesized that DBP during CPR for IHCA is lower during nighttime versus daytime. (Source: Resuscitation)
Source: Resuscitation - July 1, 2020 Category: Emergency Medicine Authors: Heather A. Wolfe, Ryan W. Morgan, Robert M. Sutton, Ron W. Reeder, Kathleen L. Meert, Murray M. Pollack, Andrew R. Yates, John T. Berger, Christopher J. Newth, Joseph A. Carcillo, Patrick S. McQuillen, Rick E. Harrison, Frank W. Moler, Todd C. Carpenter, Tags: Clinical paper Source Type: research

Early cerebral edema after cardiac arrest and its ramifications
Cerebral edema on brain imaging after cardiac arrest is often considered a harbinger of neurological catastrophe, but it should also warrant consideration as a treatment target.1 Like all injuries, this edema exists on a spectrum, with recoverable injury at one end and catastrophic brain injury or brain death at the other.2 Early cerebral edema after resuscitation may reflect widespread loss of cellular integrity, but it is exacerbated by loss of cerebral autoregulation,3,4 and inappropriate hemodynamic and ventilator treatments. (Source: Resuscitation)
Source: Resuscitation - June 30, 2020 Category: Emergency Medicine Authors: Jonathan Rud, Teresa L. May, Richard R. Riker, David B. Seder Tags: Editorial Source Type: research

Low hemoglobin and venous saturation levels are associated with poor neurological outcomes after cardiac arrest
Hemoglobin (Hb) is a main determinant of tissue oxygen delivery and anemia could be particularly harmful in post-anoxic brain injury. The aim of this study was to evaluate the association of Hb and venous Hb oxygen saturation (SvO2/ScvO2) with long-term neurological outcome in patients admitted after cardiac arrest (CA). (Source: Resuscitation)
Source: Resuscitation - June 24, 2020 Category: Emergency Medicine Authors: Federica Zama Cavicchi, Enrica Iesu, Federico Franchi, Leda Nobile, Filippo Annoni, Jean-Louis Vincent, Sabino Scolletta, Jacques Creteur, Fabio Silvio Taccone Tags: Clinical paper Source Type: research

Editorial Board
(Source: Resuscitation)
Source: Resuscitation - June 23, 2020 Category: Emergency Medicine Source Type: research

Impact of COVID-19 pandemic on emergency department services acuity and possible collateral damage
The coronavirus disease 2019 (COVID-19) spreads rapidly across the globe in early 2020.1 In Taiwan, there were 429 confirmed COVID-19 cases and 6 deaths as of April 30.2 The outbreak has created unprecedented burden on the society and health care system, particularly the frontline emergency department (ED). (Source: Resuscitation)
Source: Resuscitation - June 22, 2020 Category: Emergency Medicine Authors: Chih-Wei Sung, Tsung-Chien Lu, Cheng-Chung Fang, Chien-Hua Huang, Wen-Jone Chen, Shyr-Chyr Chen, Chu-Lin Tsai Tags: Letter to the Editor Source Type: research

Improving response to out-of-hospital cardiac arrest: The verified responder program pilot
Survival following out-of-hospital cardiac arrest (OHCA) decreases as the interval from collapse to CPR and defibrillation increases. Innovative approaches are needed to reduce response intervals, especially for private locations. (Source: Resuscitation)
Source: Resuscitation - June 21, 2020 Category: Emergency Medicine Authors: Jennifer Blackwood, Michael Mancera, Scott Bavery, Christopher Carbon, Mohamud Daya, Brent VanKeulen, Dana N. Alteneder, Jeff Helm, Jeremy Robertson, Julie Charbonneau, James M. Nania, Brian Schaeffer, Mike Lopez, Tim Loncon, Bryan Collins, Michael Charte Tags: Clinical paper Source Type: research