Adapting the EQ-5D-3L for adults with mild to moderate learning disabilities
Approximately 1.5 million adults in the UK have a learning disability. The difference between age at death for this group and the general population is 26 years for females and 22 years for males. The NHS Long... (Source: Health and Quality of Life Outcomes)
Source: Health and Quality of Life Outcomes - April 29, 2024 Category: International Medicine & Public Health Authors: John L. O ’Dwyer, Louise D. Bryant, Claire Hulme, Paul Kind and David M. Meads Tags: Research Source Type: research
Identification of Novel NSD1 variations in four Pediatric cases with sotos Syndrome
Sotos syndrome (SOTOS) is an uncommon genetic condition that manifests itself with the following distinctive features: prenatal overgrowth, facial abnormalities, and intellectual disability. This disorder is o... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - April 29, 2024 Category: Genetics & Stem Cells Authors: Zhuo Ren, Ling Yue, Hua-ying Hu, Xiao-lin Hou, Wen-qi Chen, Ya Tan, Zhe Dong and Jing Zhang Tags: Research Source Type: research
Protocol for combined N-of-1 trials to assess cerebellar neurostimulation for movement disorders in children and young adults with dyskinetic cerebral palsy
Movement and tone disorders in children and young adults with cerebral palsy are a great source of disability. Deep brain stimulation (DBS) of basal ganglia targets has a major role in the treatment of isolate... (Source: BMC Neurology)
Source: BMC Neurology - April 29, 2024 Category: Neurology Authors: M San Luciano, C R Oehrn, S S Wang, J S Tolmie, A Wiltshire, R E Graff, J Zhu and P A Starr Tags: Study Protocol Source Type: research
Adult-onset YY1-associated combined dystonia syndrome with infantile nystagmus as a diagnostic clue
In this report, we present a case of a novel YY1 variant in which the main symptoms were limb dystonia, gait disturbance, and infantile nystagmus. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - April 29, 2024 Category: Neurology Authors: In Ja Shin, Yoon Seob Kim, Joo-Yeon Lee, Min Seung Kim, Jung Han Yoon, Don Gueu Park Source Type: research
The Ethics of Full Body Skin Exams (FBSE)
Full body skin examinations (FBSEs) are part of the purview of a dermatologic exam. Because this involves examination of sensitive or “intimate” areas, there are many ethical issues involved. Herein we discuss whether screening patients with a FBSE is ethical and consistent with the ethical tenet of distributive justice, how to ethically deal with our disabled patients, how to ethically navigate patients who have been emotiona lly or physically traumatized in the past, and the ethical ramifications of the use of a chaperone. (Source: Clinics in Dermatology)
Source: Clinics in Dermatology - April 29, 2024 Category: Dermatology Authors: Jane M. Grant-Kels Tags: Ethics of Total Body Examination Source Type: research
Preference for Prompting Procedures to Address Escape-Maintained Behavior in Autistic Adolescents
AbstractDifferential reinforcement of alternative behavior (DRA) is a common strategy for escape-maintained behaviors targeted for reduction (i.e., targeted behavior) exhibited by youth with intellectual and developmental disabilities. DRA often involves various methods of prompting to ensure the instruction or task remains in place until contingencies for the DRA are met. Currently, there is little research on client preference for these different prompting strategies in the context of DRA treatments. The current study includes four participants diagnosed with autism spectrum disorder (ASD) who exhibited targeted behavior...
Source: Journal of Developmental and Physical Disabilities - April 29, 2024 Category: Disability Source Type: research
A Personalized Mediterranean Diet Improves Pain and Quality of Life in Patients with Fibromyalgia
ConclusionsThe habit of eating inflammatory foods and/or eating meals with the wrong nutritional content would increase the negative status of patients with fibromyalgia. With this study, we confirm that proper attention to feeding habits would improve the quality of life of such patients. (Source: Pain and Therapy)
Source: Pain and Therapy - April 29, 2024 Category: Anesthesiology Source Type: research
Implications of Health Equity for Children With Disabilities
This Viewpoint discusses how the National Institutes of Health designation of individuals with disabilities as a health disparity population can boost research participation and funding and expand health care access for pediatric patients with disabilities. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - April 29, 2024 Category: Pediatrics Source Type: research
Association between the severity of hard-to-treat psoriasis and the prevalence of metabolic syndrome: A hospital-based cross-sectional study in Jakarta, Indonesia
This study found most frequent components of MetS were abdominal obesity, decreased levels of HDL cholesterol, hypertension, hyperglycemia, and hypertriglyceridemia respectively. Individuals with severe hard-to-treat psoriasis had a 3.67 times more likely to have MetS rather than the mild-moderate group. (Source: PLoS One)
Source: PLoS One - April 29, 2024 Category: Biomedical Science Authors: Dina Evyana Source Type: research
Disparities in COVID-19 vaccine uptake among rural hard-to-reach population and urban high-risk groups of Bangladesh
ConclusionVaccination coverage among urbanites of high-risk group was found to be critically low. Vaccine hesitancy was also found to be high among individuals of this group. It is essential that the individuals of urban high-risk group be prioritized. Individuals from this group could be provided incentives (transport for disabled, monetary incentive to transgenders; food and medicine for drug user and floating people) and vaccination centers could be established with flexible schedule (morning/afternoon/evening sessions) so that they receive vaccine at their convenient time. Community engagement can be used for both high...
Source: PLoS One - April 29, 2024 Category: Biomedical Science Authors: Zerin Jannat Source Type: research
Untangling the knot of the best endovascular treatment for femoropopliteal artery disease
Peripheral artery disease (PAD) is an emerging, major cause of mortality, disability, and morbidity affecting more than 200 million people worldwide [1 –3]. Between the years 2000 and 2010, the prevalence of PAD increased by 13.1% in high-income countries and 28.7% in low-to-middle-income countries [1–4]. A significant association between PAD development and ageing has been established, with prevalences ranging from below 5% among individuals a ged 40–44 years to approximately 12% among individuals aged 70–74 years and approximately 20% among those aged 80–84 years [1–4]. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 29, 2024 Category: Cardiology Authors: Daniele Giacoppo Source Type: research
Molecules, Vol. 29, Pages 2052: External Guide Sequence Effectively Suppresses the Gene Expression and Replication of Herpes Simplex Virus 2
This study shows the effective and specific anti-HSV-2 activity of the RNase P-EGS approach and demonstrates the potential of EGS RNAs for anti-HSV-2 applications. (Source: Molecules)
Source: Molecules - April 29, 2024 Category: Chemistry Authors: Bin Yan Yujun Liu Yuan-Chuan Chen Fenyong Liu Tags: Article Source Type: research
Prescriptions for Antipsychotics: Youth with Intellectual/Developmental Disabilities Compared to Youth without Intellectual/Developmental Disabilities
CONCLUSION: Compared to youth without IDD, youth with IDD were more frequently dispensed antipsychotics and metformin. These findings have important implications for the health of youth with IDD.PMID:38678514 | DOI:10.1007/s10803-024-06344-z (Source: Journal of Autism and Developmental Disorders)
Source: Journal of Autism and Developmental Disorders - April 28, 2024 Category: Psychiatry Authors: Sandra Marquis N Esm é Marquis Yona Lunsky Kimberlyn M McGrail Jennifer Baumbusch Source Type: research
Prescriptions for Antipsychotics: Youth with Intellectual/Developmental Disabilities Compared to Youth without Intellectual/Developmental Disabilities
CONCLUSION: Compared to youth without IDD, youth with IDD were more frequently dispensed antipsychotics and metformin. These findings have important implications for the health of youth with IDD.PMID:38678514 | DOI:10.1007/s10803-024-06344-z (Source: Journal of Autism and Developmental Disorders)
Source: Journal of Autism and Developmental Disorders - April 28, 2024 Category: Psychiatry Authors: Sandra Marquis N Esm é Marquis Yona Lunsky Kimberlyn M McGrail Jennifer Baumbusch Source Type: research
Prescriptions for Antipsychotics: Youth with Intellectual/Developmental Disabilities Compared to Youth without Intellectual/Developmental Disabilities
CONCLUSION: Compared to youth without IDD, youth with IDD were more frequently dispensed antipsychotics and metformin. These findings have important implications for the health of youth with IDD.PMID:38678514 | DOI:10.1007/s10803-024-06344-z (Source: Journal of Autism and Developmental Disorders)
Source: Journal of Autism and Developmental Disorders - April 28, 2024 Category: Psychiatry Authors: Sandra Marquis N Esm é Marquis Yona Lunsky Kimberlyn M McGrail Jennifer Baumbusch Source Type: research
