Remote Electrical Neuromodulation for the Acute Treatment of Migraine in Patients with Chronic Migraine: An Open-Label Pilot Study
ConclusionsREN used for a series of migraine attacks was effective and well tolerated across attacks. REN may offer a safe and effective non-pharmacological alternative for acute treatment in patients with chronic migraine.Trial RegistrationClinicalTrials.gov identifier, NCT04161807. Retrospectively registered on November 13, 2019. (Source: Pain and Therapy)
Source: Pain and Therapy - July 9, 2020 Category: Anesthesiology Source Type: research

Author ’s Response to: ‘Letter to the Editor Regarding Efficacy and Safety of Diclofenac and Capsaicin Gel in Patients with Acute Back/Neck Pain: A Multicenter Randomized Controlled Study’
(Source: Pain and Therapy)
Source: Pain and Therapy - July 9, 2020 Category: Anesthesiology Source Type: research

Letter to the Editor Regarding Efficacy and Safety of Diclofenac and Capsaicin Gel in Patients with Acute Back/Neck Pain: A Multicenter Randomized Controlled Study
(Source: Pain and Therapy)
Source: Pain and Therapy - July 9, 2020 Category: Anesthesiology Source Type: research

Images in Practice: Replacement of an 18-Year-Old Spinal Cord Stimulator Paddle Lead with Cylindrical Leads Under Direct Visualization
(Source: Pain and Therapy)
Source: Pain and Therapy - July 4, 2020 Category: Anesthesiology Source Type: research

Successful Pain Relief by Local Injection Under Ultrasound Guidance in a Patient with Anatomical Abnormality of Cervical 5 Nerve Root
(Source: Pain and Therapy)
Source: Pain and Therapy - July 4, 2020 Category: Anesthesiology Source Type: research

Sleep Disorders and Headache: A Review of Correlation and Mutual Influence
AbstractThe review is devoted to the complex relationship between headache and sleep disorders. The shared neuroanatomical structures of the nervous system involved in pain perception and sleep are shown, and mechanisms of comorbidity between headaches and sleep disorders are considered. Various types of headaches in the continuum of the sleep –wake cycle are described. Both pharmacological and non-pharmacological approaches to treatment are examined in detail, with the biochemical basis of the drug action. (Source: Pain and Therapy)
Source: Pain and Therapy - July 3, 2020 Category: Anesthesiology Source Type: research

Clinical Efficacy and Safety Profile of Topical Etofenamate in the Treatment of Patients with Musculoskeletal Disorders: A Systematic Review
ConclusionsThe clinical evidence currently available suggests that etofenamate is an effective therapeutic option for the management of musculoskeletal disorders, such as blunt traumas, lumbago or osteoarthrosis. However, larger and well-controlled clinical trials comparing the efficacy and safety of etofenamate with other newer topical NSAIDs are warranted. (Source: Pain and Therapy)
Source: Pain and Therapy - June 19, 2020 Category: Anesthesiology Source Type: research

A Bilateral Lumbar Multidermatomal Herpes Zoster in an Elderly Woman with Chronic Kidney Disease
AbstractHerpes zoster (HZ) is a painful rash caused by the reactivation of the varicella-zoster virus (VZV) permanently latent within the cranial or dorsal root ganglia. Usually the rash presents in only one side of the body, in a single dermatome or restricted to a part of it. In immunocompromised patients, more than one contiguous unilateral dermatome, called multidermatomal HZ, has been described, usually in cervical dermatomes. Bilateral rash is rare. Besides immunosuppression, the major risk factors for virus reactivation are older age and female gender. This is a case of a bilateral lumbar multidermatomal HZ in an el...
Source: Pain and Therapy - June 8, 2020 Category: Anesthesiology Source Type: research

Clinical Validation of a Multi-Biomarker Assay for the Evaluation of Chronic Pain Patients in a Cross-Sectional, Observational Study
We describe the clinical validation of a multi-biomarker assay with algorithmic analysis known as the Foundation Pain Index (FPI) in diverse cohorts of chronic pain patients in a prospective, cross-sectional, observational validation study. Levels of 11 urinary pain biomarkers were measured and tabulated using a proprietary algorithm to generate FPI scores for chronic pain subjects (N = 153) and age- and sex-matched pain-free controls (N = 334).ResultsFPI scores were significantly correlated with the 36-Item Short Form Health Survey (SF-36) scores among chronic pain subjects (P value  
Source: Pain and Therapy - June 3, 2020 Category: Anesthesiology Source Type: research

“Triaging” Chronic Migraine Patients in Need of CGRP(r) Monoclonal Antibodies
(Source: Pain and Therapy)
Source: Pain and Therapy - April 30, 2020 Category: Anesthesiology Source Type: research

Triple Intrathecal Combination Therapy for End-Stage Cancer-Related Refractory Pain: A Prospective Observational Study with Two-Month Follow-Up
AbstractIntroductionIn cancer-related pain refractory to systemic opioids, intrathecal (IT) administration of morphine can be a useful strategy. In clinical practice, IT morphine is usually combined with other drugs with different mechanisms of action, in order to obtain a synergistic analgesic effect. However, the discussion on efficacy and safety of IT combination therapy is still ongoing. The aim of this observational study was to report the effects of an IT combination of low doses of ziconotide, morphine, and levobupivacaine in end-stage cancer refractory pain.MethodsSixty adult patients, 21 females and 39 males, were...
Source: Pain and Therapy - April 29, 2020 Category: Anesthesiology Source Type: research

Acute Migraine Prescription Patterns Vary by Baseline Cardiovascular Risk and Clinical Characteristics: A Real-World Evidence Study
ConclusionPeople with migraine who had more cardiovascular risk factors and greater 1-year MI risk score were disproportionately prescribed opiates and NSAIDs compared to triptans. Future research should explore unmet needs for patients with disorders for which triptan therapy is contraindicated. (Source: Pain and Therapy)
Source: Pain and Therapy - April 23, 2020 Category: Anesthesiology Source Type: research

Anti-Inflammatory and Anti-Nociceptive Effects of Cocoa: A Review on Future Perspectives in Treatment of Pain
AbstractCocoa has been reported to have medicinal properties. It contains a wide range of phytochemicals, including polyphenols, which have been shown to exert anti-inflammatory and antioxidant actions, and also to have a positive effect on pain. Other components of cocoa might be able to positively influence pain perception through various mechanisms. Despite encouraging results from preclinical studies, there is a lack of evidence of antinociceptive effects of cocoa from clinical trials in humans. Further research is needed to better identify the active principles in cocoa, to understand the underlying mechanisms of acti...
Source: Pain and Therapy - April 20, 2020 Category: Anesthesiology Source Type: research

Sufentanil Sublingual for Acute Post-Operative Pain: A Systematic Literature Review Focused on Pain Intensity, Adverse Events, and Patient Satisfaction
ConclusionsSSTS is an important system for the management of moderate-to-severe acute pain in a hospital setting. SSTS is well tolerated, with no unexpected adverse events (AEs) and no clinically meaningful vital sign changes. These data confirm the safety and tolerability of the SSTS. Successful pain management resulted in a high level of acceptance of the SSTS by patients with high satisfaction for the method of pain control. (Source: Pain and Therapy)
Source: Pain and Therapy - April 17, 2020 Category: Anesthesiology Source Type: research

Neuropathic Pain Registries Improve Pain Management and Provide More Efficacious Planning of Healthcare Services
AbstractThe first official health registry dates back to the 19th century and was proven to be very useful for gathering important information regarding a specific disease. Since then, data collection through registries is gaining more popularity, as it can offer useful information not only to health providers but also to healthcare planning services. Health registries could come along with randomized controlled trials and support or reject their findings in the “real world”. Pain registries and neuropathic pain registries have proven to be very potent weapons in the armory of the pain specialist and are growin...
Source: Pain and Therapy - April 17, 2020 Category: Anesthesiology Source Type: research

Fully Integrated Oncology and Palliative Care Services at a Local Hospital in Mid-Norway: Development and Operation of an Innovative Care Delivery Model
ConclusionThis delivery model of integrated outpatient cancer and palliative care is particularly relevant in rural regions allowing cancer patients access to palliative care earlier in the disease trajectory and closer to home (Source: Pain and Therapy)
Source: Pain and Therapy - April 9, 2020 Category: Anesthesiology Source Type: research

Correction to: Injection Techniques for Common Chronic Pain Conditions of the Hand: A Comprehensive Review
The mid initial of one of the authors (Source: Pain and Therapy)
Source: Pain and Therapy - March 31, 2020 Category: Anesthesiology Source Type: research

An Evidence-Based Review of Fremanezumab for the Treatment of Migraine
AbstractMigraine headache is a common, chronic, debilitating disease with a complex etiology. Current therapy for migraine headache comprises either treatments targeting acute migraine pain or prophylactic therapy aimed at increasing the length of time between migraine episodes. Recent evidence suggests that calcium gene-related peptide (CGRP) is a critical component in the pathogenesis of migraines. Fremanezumab, a monoclonal antibody against CGRP, was recently approved by the Food and Drug Administration (FDA) after multiple studies showed that it was well-tolerated, safe, and effective in the treatment of migraines. Fur...
Source: Pain and Therapy - March 28, 2020 Category: Anesthesiology Source Type: research

Efficacy and Safety of Diclofenac  + Capsaicin Gel in Patients with Acute Back/Neck Pain: A Multicenter Randomized Controlled Study
ConclusionCapsaicin alone and capsaicin  + diclofenac showed superior benefit compared with placebo. However, diclofenac alone demonstrated efficacy comparable with placebo, and therefore its addition to capsaicin added no increased pain relief over capsaicin alone.Trial registrationClinicalTrials.gov identifier; NCT02700815. (Source: Pain and Therapy)
Source: Pain and Therapy - March 27, 2020 Category: Anesthesiology Source Type: research

Resolving Issues About Efficacy and Safety of Low-Dose Codeine in Combination Analgesic Drugs: A Systematic Review
ConclusionsLow-dose codeine combinations are effective after a single application in treating acute pain. Codeine in doses  ≤ 30 mg and higher was considered safe since only mild to moderate side-effects were observed. There is no indication in the available sources which clearly links low doses of codeine to substance use disorder in non-dependent subjects. (Source: Pain and Therapy)
Source: Pain and Therapy - March 14, 2020 Category: Anesthesiology Source Type: research

Kampo for the Treatment of Pain in Japan: A Review
AbstractKampo, a branch of traditional Japanese herbal medicine, has been the backbone of Japanese medicine for more than 1500  years. The health insurance system in Japan allows patients to access both Western and Kampo medical care at the same time in the same medical institution. Kampo has been used for the treatment of not only acute but also chronic pain in Japan. In this review, we will elaborate on the short history of Kampo, its basic concepts, and use for the treatment of pain. (Source: Pain and Therapy)
Source: Pain and Therapy - March 10, 2020 Category: Anesthesiology Source Type: research

Injection Techniques for Common Chronic Pain Conditions of the Foot: A Comprehensive Review
AbstractPurpose of ReviewThis is a comprehensive literature review of the available evidence and techniques of foot injections for chronic pain conditions. It briefly describes common foot chronic pain syndromes and then reviews available injection techniques for each of these syndromes, weighing the available evidence and comparing the available approaches.Recent FindingsFoot and ankle pain affects 20% of the population over 50 and significantly impairs mobility and ability to participate in activities of daily living (ADLs), as well as increases fall risk. It is commonly treated with costly surgery, at times with questio...
Source: Pain and Therapy - February 27, 2020 Category: Anesthesiology Source Type: research

Injection Techniques for Common Chronic Pain Conditions of the Hand: A Comprehensive Review
ConclusionsChronic hand pain is a prevalent and serious condition and can cause significant morbidity and disability and interferes with independence and activities of daily living. Conservative treatment remains the first line of treatment; however, when first-line treatments fail, steroid injections can usually provide benefit. In some cases, HA or Botox may also be beneficial. US-guidance is increasing in hand injection and almost ubiquitously provides safer, more effective injections. Hand surgery remains the alternative for refractory pain. (Source: Pain and Therapy)
Source: Pain and Therapy - February 25, 2020 Category: Anesthesiology Source Type: research

Tramadol/Diclofenac Fixed-Dose Combination: A Review of Its Use in Severe Acute Pain
AbstractPain is a health issue affecting all populations, regardless of age, gender, economic status, race, or geography. Acute pain is the most common type of pain, with a complex aetiology. Inadequately managed acute pain adversely affects quality of life and imposes significant economic burden. The majority of the available pain-relieving drugs have monomodal mechanisms of analgesia, which necessitates combining drugs with non-redundant mechanisms of action in order to provide adequate pain relief and reduce the side effects from higher doses of individual drugs. In this regard, combining an oral opioid (such as codeine...
Source: Pain and Therapy - February 15, 2020 Category: Anesthesiology Source Type: research

Results of Mirogabalin Treatment for Diabetic Peripheral Neuropathic Pain in Asian Subjects: A Phase 2, Double-Blind, Randomized, Placebo-Controlled, Study
ConclusionsIn Asian subjects with DPNP, mirogabalin (5, 10, and 15  mg BID) was well tolerated. Although no significant differences were observed in the primary endpoint, there was a tendency toward improvement of pain with mirogabalin treatment, and this trend was also observed in the secondary endpoints.Trial RegistrationClinicalTrials.gov identifier, NCT01504412. (Source: Pain and Therapy)
Source: Pain and Therapy - February 12, 2020 Category: Anesthesiology Source Type: research

Mandibular Nerve Block for Long-Term Pain Relief in a Case of Refractory Burning Mouth Syndrome
(Source: Pain and Therapy)
Source: Pain and Therapy - February 12, 2020 Category: Anesthesiology Source Type: research

Statins and Neuropathic Pain: A Narrative Review
AbstractThe frequently prescribed drug class of statins have pleiotropic effects and have been implicated in neuropathic pain syndromes. This narrative review examines studies of statin-induced neuropathic pain which to date have been conducted only in animal models. However, the pathophysiology of diabetic neuropathy in humans may shed some light on the etiology of neuropathic pain. Statins have exhibited a paradoxical effect in that statins appear to reduce neuropathic pain in animals but have been associated with neuropathic pain in humans. While there are certain postulated mechanisms offering elucidation as to how sta...
Source: Pain and Therapy - February 4, 2020 Category: Anesthesiology Source Type: research

Rehabilitation for Low Back Pain: A Narrative Review for Managing Pain and Improving Function in Acute and Chronic Conditions
AbstractLow back pain (LBP) is prevalent and may transition into chronic LBP (cLBP) with associated reduced quality of life, pain, and disability. Because cLBP affects a heterogenous population, rehabilitation efforts must be individualized to meet the needs of various patient populations as well as individuals. This narrative review evaluated the many approaches to LBP rehabilitation including treatment-based classifications and specific types of rehabilitation efforts from exercise and physical therapy to spinal manipulation and bracing. Clinicians caring for patients with LBP or cLBP must be aware of the various options...
Source: Pain and Therapy - January 31, 2020 Category: Anesthesiology Source Type: research

Correction to: Pathophysiologic Approach to Pain Therapy for Complex Pain Entities: A Narrative Review
Figure  1 caption was processed and published incorrectly. The correct caption should read as follows: (Source: Pain and Therapy)
Source: Pain and Therapy - January 31, 2020 Category: Anesthesiology Source Type: research

Kratom —Pharmacology, Clinical Implications, and Outlook: A Comprehensive Review
AbstractKratom, orMitragyna, is a tropical plant indigenous to Southeast Asia, with unique pharmacological properties. It is commonly consumed by preparing the leaves into decoction or tea, or by grinding them into a powder. Recent evidence has revealed that kratom has physiological effects similar to opioids, including pain relief and euphoria, as well as stimulant properties, which together raise potential concern for dependence and addiction. Moreover, growing evidence suggests that the prevalence of kratom use is increasing in many parts of the world, raising important considerations for healthcare providers. This manu...
Source: Pain and Therapy - January 28, 2020 Category: Anesthesiology Source Type: research

A Narrative Pharmacological Review of Buprenorphine: A Unique Opioid for the Treatment of Chronic Pain
AbstractBuprenorphine is a Schedule III opioid analgesic with unique pharmacodynamic and pharmacokinetic properties that may be preferable to those of Schedule II full μ-opioid receptor agonists. The structure of buprenorphine allows for multimechanistic interactions with opioid receptors μ, δ, κ, and opioid receptor-like 1. Buprenorphine is considered a partial agonist with very high binding affinity for the μ-opioid receptor, an antagonist with high binding affinity for the δ- and κ-opioid receptors, and an agonist with low binding affinity for the opioid receptor-like 1 receptor. Partial...
Source: Pain and Therapy - January 28, 2020 Category: Anesthesiology Source Type: research

Chronic Pain Following Cosmetic Breast Surgery: A Comprehensive Review
ConclusionsThe present review provides a discussion of clinical presentation, pathophysiology, and treatment and preventative strategies for chronic breast pain following cosmetic surgery. This review provides evidence from multiple randomized controlled trials (RCTs) and systematic reviews of efficacy and effectiveness. While chronic postoperative breast pain remains challenging to treat, various preventative strategies have been described to improve postoperative pain outcomes. (Source: Pain and Therapy)
Source: Pain and Therapy - January 28, 2020 Category: Anesthesiology Source Type: research

Non-Opioid Perioperative Pain Strategies for the Clinician: A Narrative Review
AbstractAlternative and non-opioid options for pain management are necessary in perioperative patient care. Opioids are no longer touted as cure-all medications, and furthermore, there have been tremendous advances in alternative therapies such as in interventional pain, physical therapy, exercise, and nutritional counseling that have proven benefits to combat pain. The center for disease control now strongly recommends the use of multimodal analgesia and multidisciplinary approaches based on the individual needs of patients: personalized medicine. In this manuscript, the specifics of non-opioid pharmacological and non-pha...
Source: Pain and Therapy - January 13, 2020 Category: Anesthesiology Source Type: research

A Randomized, Double-Blind, Placebo-Controlled Trial of Ibuprofen Lysinate in Comparison to Ibuprofen Acid for Acute Postoperative Dental Pain
ConclusionsA single dose of ibuprofen lysinate is non-inferior to ibuprofen acid in terms of analgesic efficacy, onset of action, and tolerability in patients who have recently undergone dental surgery.Trial RegistrationEudraCT No. 2006-006942-33.Plain Language SummaryPlain language summary available for this article. (Source: Pain and Therapy)
Source: Pain and Therapy - January 7, 2020 Category: Anesthesiology Source Type: research

Pathophysiologic Approach to Pain Therapy for Complex Pain Entities: A Narrative Review
AbstractPain management is challenging for both clinicians and patients. In fact, pain patients are frequently undertreated or even completely untreated. Optimal treatment is based on targeting the underlying mechanisms of pain and tailoring the management modality for each patient using a personalized approach. This narrative review deals with pain conditions that have a complex underlying mechanism and need an individualized and frequently multifactorial approach to pain management.  The research is based on previously conducted studies, and does not contain any studies with human participants or animals perfor...
Source: Pain and Therapy - January 4, 2020 Category: Anesthesiology Source Type: research

Preventive Epidural Analgesia in Bilateral Single-Stage Knee Arthroplasty: A Randomized Controlled Trial
ConclusionsPreventive epidural analgesia reduces the severity and number of chronic pain days after bilateral single-stage knee replacement.Trial RegistrationThe study was registered in the Indian national registry (CTRI/2017/03/008240 on 28/03/2017). (Source: Pain and Therapy)
Source: Pain and Therapy - January 3, 2020 Category: Anesthesiology Source Type: research

Successful and Complete Recovery of the Ulnar Nerve After Eight Years of Chronic Injury Through Local Steroid Injections: A Case Report
We present a case of a 33-year-old female with a chronic loss of the ulnar nerve function for 8  years after traumatic laceration. After that, she regained the functions of ulnar nerve after nerve stimulation by peri-ulnar nerve injection of methylprednisolone and lidocaine. The theory behind using steroids is related to the fact that the immune system could induce a secondary injury that int erferes with the recovery. Many studies have shown effectiveness in using steroids alone or when combined with other substances on nerve regeneration in animal models. We believe that this is the first report of nerve recovery us...
Source: Pain and Therapy - January 3, 2020 Category: Anesthesiology Source Type: research

Images in Practice: Successful Recapture of Spinal Cord Stimulator Paresthesia Coverage via Generator Reprogramming in a Patient with a Severely Displaced Percutaneous Trial Lead
(Source: Pain and Therapy)
Source: Pain and Therapy - December 27, 2019 Category: Anesthesiology Source Type: research

Images in Practice: Multifidus Muscle Dysfunction Characterized by Fat Infiltration in a Patient with Chronic Lumbar Back Pain
(Source: Pain and Therapy)
Source: Pain and Therapy - December 27, 2019 Category: Anesthesiology Source Type: research

Combination of Rehabilitative Therapy with Ultramicronized Palmitoylethanolamide for Chronic Low Back Pain: An Observational Study
ConclusionsThe multiple action of PEA in combination with CAM therapies may represent the multitarget approach needed to tackle the as-yet unsolved problem of chronic pain resistant to conventional therapies. (Source: Pain and Therapy)
Source: Pain and Therapy - December 20, 2019 Category: Anesthesiology Source Type: research

Presentation and Management of a Postoperative Spinal Pseudomeningocele
(Source: Pain and Therapy)
Source: Pain and Therapy - November 18, 2019 Category: Anesthesiology Source Type: research

Extensive Degeneration of Vertebral Body Leading to Baastrup ’s Disease: A Radiographic Review of an Image
This article is based on previously conducted studies and does not contain any studies with human participants or animals performed by any of the authors. Informed consent for publication was obtained from the participant. (Source: Pain and Therapy)
Source: Pain and Therapy - November 4, 2019 Category: Anesthesiology Source Type: research

In Memoriam: Daniel Callahan (1930 –2019)
(Source: Pain and Therapy)
Source: Pain and Therapy - August 20, 2019 Category: Anesthesiology Source Type: research

A Case Study of Combined Perception-Based and Perception-Free Spinal Cord Stimulator Therapy for the Management of Persistent Pain after a Total Knee Arthroplasty
We present a 71-year-old Caucasian non-Hispanic male who presented with chronic left knee pain after undergoing a total knee arthroplasty (TKA) 18  months prior. Following his TKA, he reported doing well in the acute post-operative period but began to develop progressively worsening left knee pain at approximately the third post-operative week. He underwent a successful spinal cord stimulator (SCS) trial and subsequent implantation of two 16- contact Boston Scientific leads with a Boston Scientific Spectra WaveWriterTM SCS system. Upon first post-procedural follow-up, and moreover at his 6-month follow-up, the patient...
Source: Pain and Therapy - August 20, 2019 Category: Anesthesiology Source Type: research

Opioids and the Predilection for Violence in the Pain Clinic: A Physician ’s Perspective
This article is based on previously conducted studies and does not contain any studies with human participants or animals performed by any of the authors. (Source: Pain and Therapy)
Source: Pain and Therapy - August 20, 2019 Category: Anesthesiology Source Type: research

Stopping or Decreasing Opioid Therapy in Patients on Chronic Opioid Therapy
AbstractWith the rising concerns about long-term opioid use, particularly in patients with chronic noncancer pain, more and more patients are being considered for decreased doses or discontinuation of opioid therapy. This is a challenging clinical situation for both patient and clinician and should be presented in a shared decision-making model so that the patient understands the risks of opioid therapy and how the therapy will be discontinued. The patient should be aware of the long-range plan and its milestones. It is imperative that alternate pain control treatments be made available to the patient early, and that the p...
Source: Pain and Therapy - August 3, 2019 Category: Anesthesiology Source Type: research

Impact of Patient-Controlled Analgesia (PCA) Smart Pump-Electronic Health Record (EHR) Interoperability with Auto-Documentation on Chart Completion in a Community Hospital Setting
This study is the first to evaluate the association between auto-documentation of opioid administration provided by PCA smart pump —electronic health record (EHR) interoperability and the completion of PCA opioid administration charting tasks.MethodsThis retrospective cohort study was conducted at Lancaster General Hospital, Lancaster, Pennsylvania. Patients were assigned to pre-auto-documentation (n = 55) or post-auto-documentation groups (n = 58) based on whether they received PCA therapy prior to or after PCA-EHR interoperability was implemented. Charting of PCA therapy included documen...
Source: Pain and Therapy - July 26, 2019 Category: Anesthesiology Source Type: research

Associations Between Headache-Free Days and Patient-Reported Outcomes Among Migraine Patients: A Cross-Sectional Analysis of Survey Data in Europe
This study aimed to assess the associations between the number of headache-free days (HFDs) and health-related quality of life (HRQoL), work productivity and activity impairment (WPAI), and healthcare resource utilization (HRU) in patients with migraine in the EU5 (France, Germany, Italy, Spain, and the United Kingdom).MethodsThis retrospective cross-sectional study collected survey responses from adults aged  ≥ 18 years from the 2017 National Health and Wellness Survey (N = 62,000). Migraine patients with a physician’s diagnosis of migraine and who had experienced at least 4 month...
Source: Pain and Therapy - July 26, 2019 Category: Anesthesiology Source Type: research

Viscosupplementation for Management of Knee Osteoarthritis from an Indian Perspective: An Expert Consensus Report
ConclusionIn this pioneering attempt, the document lays down structured, expert consensus-based statements to guide and align practitioners on the appropriate use of IAHA in the Indian setting.FundingDr. Reddy ’s Laboratories Ltd. (Source: Pain and Therapy)
Source: Pain and Therapy - July 15, 2019 Category: Anesthesiology Source Type: research

Effect of Migraine Headache on Productivity of Patients According to Migraine Disability Assessment Score: A Cross-Sectional Study
ConclusionsThe majority of migraine patients were found to have severe disability, which affected their daily work and social activities. Despite an increase in disability rate due to migraine, people do not seek regular medical care for this type of headache in Pakistan. (Source: Pain and Therapy)
Source: Pain and Therapy - July 9, 2019 Category: Anesthesiology Source Type: research