Know DBS: patient perceptions and knowledge of deep brain stimulation in Parkinson's disease
CONCLUSION: Our study provides a detailed understanding of patient perceptions of DBS for PD, including the benefits, challenges, and misconceptions. Our findings underscore the importance of identifying the causes of disparities in patient knowledge and perceptions regarding DBS to tailor patient counseling and ensure optimal treatment outcomes.PMID:38455848 | PMC:PMC10919129 | DOI:10.1177/17562864241233038 (Source: Adv Data)
Source: Adv Data - March 8, 2024 Category: Epidemiology Authors: Meagen Salinas Umar Yazdani Austin Oblack Bradley McDaniels Nida Ahmed Bilal Haque Nader Pouratian Shilpa Chitnis Source Type: research
Know DBS: patient perceptions and knowledge of deep brain stimulation in Parkinson's disease
CONCLUSION: Our study provides a detailed understanding of patient perceptions of DBS for PD, including the benefits, challenges, and misconceptions. Our findings underscore the importance of identifying the causes of disparities in patient knowledge and perceptions regarding DBS to tailor patient counseling and ensure optimal treatment outcomes.PMID:38455848 | PMC:PMC10919129 | DOI:10.1177/17562864241233038 (Source: Adv Data)
Source: Adv Data - March 8, 2024 Category: Epidemiology Authors: Meagen Salinas Umar Yazdani Austin Oblack Bradley McDaniels Nida Ahmed Bilal Haque Nader Pouratian Shilpa Chitnis Source Type: research
Effects of subthalamic nucleus deep brain stimulation using different frequency programming paradigms on axial symptoms in advanced Parkinson ’s disease
ConclusionOur findings indicate that HFS is ineffective at improving the majority of axial symptoms in advanced PD. However, both the LFS and VFS programming paradigms exhibit significant improvements in various axial symptoms. (Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - March 8, 2024 Category: Neurosurgery Source Type: research
Deep brain stimulation of the subthalamic nucleus increases the risk of sialorrhea in patients with advanced Parkinson's disease
Sialorrhea is a common neurological manifestation of Parkinson's disease (PD). No specifically designed prospective study has tested the effects of deep brain stimulation of the subthalamic nucleus (STN-DBS) on sialorrhea in patients with advanced PD. We focused on the effect of STN-DBS on the incidence of sialorrhea in patients with PD. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - March 8, 2024 Category: Neurology Authors: Jinxing Sun, Lian Cheng, Li Zhenke, Junheng Jia, Qianqian Wu, Ying Hou, Qi Wang, Guangjian Zhang, Hong Wang, Xingang Li, Weiguo Li, Chao Zhang Source Type: research
Effects of subthalamic nucleus deep brain stimulation using different frequency programming paradigms on axial symptoms in advanced Parkinson ’s disease
ConclusionOur findings indicate that HFS is ineffective at improving the majority of axial symptoms in advanced PD. However, both the LFS and VFS programming paradigms exhibit significant improvements in various axial symptoms. (Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - March 8, 2024 Category: Neurosurgery Source Type: research
The changing landscape of palliative epilepsy surgery for Lennox Gastaut Syndrome
Lennox Gastaut Syndrome (LGS) is characterized by drug-resistant epilepsy that typically leads to decreased quality of life and deleterious neurodevelopmental comorbidities from medically refractory seizures. In recent years there has been a dramatic increase in the development and availability of novel treatment strategies for Lennox Gastaut Syndrome patient to improve seizure. Recent advances in neuromodulation and minimally invasive magnetic resonance guided laser interstitial thermal therapy (MRgLITT) have paved the way for new treatments strategies including deep brain stimulation (DBS), responsive neurostimulation (R...
Source: Frontiers in Neurology - March 7, 2024 Category: Neurology Source Type: research
Amplitude Adaptive Modulation of Neural Oscillations Over Long-Term Dynamic Conditions: A Computational Study
In this study, we proposed an online optimized amplitude adaptive strategy based on the particle swarm optimization (PSO) and proportional–integral–differential (PID) controller for modulation of the beta oscillation in a PD mean field model over long-term dynamic conditions. The strategy aimed to calculate the stimulation amplitude adapting to the fluctuations caused by circadian rhythm, medication rhythm, and stochasticity in the basal ganglia–thalamus–cortical circuit. The PID gains were optimized online using PSO, based on modulation accuracy, mean stimulation amplitude, and stimulation variation. The results s...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - March 6, 2024 Category: Neuroscience Source Type: research
Compulsive programming in a patient with deep brain stimulation for obsessive-compulsive disorder
Asian J Psychiatr. 2024 Feb 24;95:103980. doi: 10.1016/j.ajp.2024.103980. Online ahead of print.NO ABSTRACTPMID:38447286 | DOI:10.1016/j.ajp.2024.103980 (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - March 6, 2024 Category: Psychiatry Authors: Sneha V Ganaraja Lavanya P Sharma Shyam Sundar Arumugham Sandeep Vaishya Dwarakanath Srinivas Source Type: research
Bilateral primary motor area intermittent theta-burst stimulation may alleviate gait and postural disturbances in Parkinson's disease patients by astrocytic modulation, caudate volume changes, and increased functional neuroplasticity
Axial signs, such as gait disturbances and postural abnormalities, are common symptoms in advanced Parkinson's disease (PD). Postural instability is closely linked with both gait and balance dysfunction, and these conditions are directly related to the risk of falls. Compared to dyskinesia and motor complications, gait and postural dysfunctions are some of the most disabling symptoms for individuals with PD and are a major contributor to loss of autonomy and diminished quality of life. In addition, debilitating axial symptoms are common as the condition progresses, result in a substantial reduction in the therapeutic respo...
Source: Parkinsonism and Related Disorders - March 6, 2024 Category: Neurology Authors: Ra úl Rashid-López, Paloma Macías-García, Álvaro J. Cruz-Gómez, Francisco L. Sánchez-Fernández, Fátima Cano-Cano, Florencia Sanmartino, Esteban Sarrias-Arrabal, Elena Lozano-Soto, Constantino Méndez-Bértolo, Fernando López-Sosa, Álvaro Gonzá Tags: Correspondence Source Type: research
Effect of the closed-loop hippocampal low-frequency stimulation on seizure severity, learning, and memory in pilocarpine epilepsy rat model
CONCLUSION: Applying closed-loop, low-frequency DBS at seizure onset reduced seizure severity and improved memory. In addition, the changes in power, coherence, and coupling of the LFP oscillations in the hippocampus and mPFC demonstrate low-frequency DBS efficacy as an antiepileptic treatment, returning LFPs to a seemingly non-seizure state in subjects that received DBS.PMID:38439573 | DOI:10.1111/cns.14656 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - March 5, 2024 Category: Neuroscience Authors: Meysam Zare Mahmoud Rezaei Milad Nazari Nastaran Kosarmadar Mona Faraz Victoria Barkley Amir Shojaei Mohammad Reza Raoufy Javad Mirnajafi-Zadeh Source Type: research
Bibliometric Analysis of Brain Stimulation Technologies in Sleep Disorders
CONCLUSIONS Our study used CiteSpace software to analyze 459 studies published since 1999 on brain stimulation techniques for the treatment of sleep disorders, revealing research trends and the current state of the field. Our results will help researchers to understand the existing research quickly and provide direction for future research.PMID:38439525 | DOI:10.12659/MSM.942687 (Source: Medical Science Monitor)
Source: Medical Science Monitor - March 5, 2024 Category: Research Authors: Chao Shen Zhao-Di Wang Wen-Jun Qian Cheng-Fan Wu Su-Rong Qian Tong Tang Source Type: research
Effect of the closed-loop hippocampal low-frequency stimulation on seizure severity, learning, and memory in pilocarpine epilepsy rat model
CONCLUSION: Applying closed-loop, low-frequency DBS at seizure onset reduced seizure severity and improved memory. In addition, the changes in power, coherence, and coupling of the LFP oscillations in the hippocampus and mPFC demonstrate low-frequency DBS efficacy as an antiepileptic treatment, returning LFPs to a seemingly non-seizure state in subjects that received DBS.PMID:38439573 | PMC:PMC10912795 | DOI:10.1111/cns.14656 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - March 5, 2024 Category: Neuroscience Authors: Meysam Zare Mahmoud Rezaei Milad Nazari Nastaran Kosarmadar Mona Faraz Victoria Barkley Amir Shojaei Mohammad Reza Raoufy Javad Mirnajafi-Zadeh Source Type: research
Physiological effects of dual target DBS in an individual with Parkinson's disease and a sensing-enabled pulse generator
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) or globus pallidus (GP) is an established therapy for Parkinson's disease (PD). Novel DBS devices can record local field potential (LFP) physiomarkers from the STN or GP. While beta (13 –30 Hz) and gamma (40–90 Hz) STN and GP LFP oscillations correlate with PD motor severity and with therapeutic effects of treatments, STN-GP interactions in electrophysiology in patients with PD are not well characterized. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - March 5, 2024 Category: Neurology Authors: Daniel D. Cummins, Stephanie S. Sandoval-Pistorius, Stephanie Cernera, Rodrigo Fernandez-Gajardo, Lauren Hammer, Philip A. Starr Tags: Short communication Source Type: research
Real-world local field potential recordings in patients with deep brain stimulation for Parkinson's disease
Deep brain stimulation (DBS) advances enable the recording of local field potentials (LFP) in real-world settings. LFP recordings from the subthalamic nucleus (STN) and globus pallidus internus (GPi) in people with Parkinson's disease (PwPD) have illuminated the role of oscillatory synchronization in parkinsonian motor symptoms [1,2]. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - March 5, 2024 Category: Neurology Authors: Alfonso Fasano, Hideo Mure, Sarah Kathleen Bick, Mya Schiess, Thomas Witt, Katsuo Kimura, Alexa Singer, Claudia Sannelli, Nathan Morelli, Genko Oyama, PSR Study Group Tags: Correspondence Source Type: research
