Clinical evaluation of a stereotactic system for single-stage deep brain stimulation surgery under general anesthesia: technical note
CONCLUSIONS: The stereotactic system facilitated safe and effective asleep, single-stage DBS surgery, maintaining traditional lead accuracy standards.PMID:38489816 | DOI:10.3171/2024.1.JNS232563 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 15, 2024 Category: Neurosurgery Authors: Kristen M Scheitler Aaron E Rusheen Jason Yuen Abhinav Goyal Sukwoo Hong Gamaleldin M Osman Basel Sharaf Bryan T Klassen Sanjeet S Grewal Kai J Miller Hojin Shin Yoonbae Oh Kendall H Lee Source Type: research
Real-time field-programmable gate array-based closed-loop deep brain stimulation platform targeting cerebellar circuitry rescues motor deficits in a mouse model of cerebellar ataxia
CONCLUSION: Our real-time FPGA-based DCN-DBS system could be a potential clinical strategy for alleviating cerebellar ataxia and other movement disorders.PMID:38488445 | DOI:10.1111/cns.14638 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - March 15, 2024 Category: Neuroscience Authors: Gajendra Kumar Zhanhong Zhou Zhihua Wang Kin Ming Kwan Chung Tin Chi Him Eddie Ma Source Type: research
Real-time field-programmable gate array-based closed-loop deep brain stimulation platform targeting cerebellar circuitry rescues motor deficits in a mouse model of cerebellar ataxia
CONCLUSION: Our real-time FPGA-based DCN-DBS system could be a potential clinical strategy for alleviating cerebellar ataxia and other movement disorders.PMID:38488445 | PMC:PMC10941591 | DOI:10.1111/cns.14638 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - March 15, 2024 Category: Neuroscience Authors: Gajendra Kumar Zhanhong Zhou Zhihua Wang Kin Ming Kwan Chung Tin Chi Him Eddie Ma Source Type: research
Clinical evaluation of a stereotactic system for single-stage deep brain stimulation surgery under general anesthesia: technical note
CONCLUSIONS: The stereotactic system facilitated safe and effective asleep, single-stage DBS surgery, maintaining traditional lead accuracy standards.PMID:38489816 | DOI:10.3171/2024.1.JNS232563 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 15, 2024 Category: Neurosurgery Authors: Kristen M Scheitler Aaron E Rusheen Jason Yuen Abhinav Goyal Sukwoo Hong Gamaleldin M Osman Basel Sharaf Bryan T Klassen Sanjeet S Grewal Kai J Miller Hojin Shin Yoonbae Oh Kendall H Lee Source Type: research
Topographical anatomy of the subthalamic region with special interest in the human medial forebrain bundle
CONCLUSIONS: According to this study's findings, the streamlines of the MFB described by tractography arise from the limitations of the diffusion-weighted MRI fiber tracking method and actually correspond to subthalamic fiber bundles, especially the ansa lenticularis and lenticular fasciculus, which erroneously continue in the anterior limb of the internal capsule, toward the prefrontal cortex.PMID:38489821 | DOI:10.3171/2024.1.JNS232066 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 15, 2024 Category: Neurosurgery Authors: Cintia Meszaros Peter Kurucz Gabor Baksa Alan Alpar Oliver Ganslandt Sebastian Brandner Laszlo Barany Source Type: research
Intracranial self-stimulation reverses impaired spatial learning and regulates serum microRNA levels in a streptozotocin-induced rat model of Alzheimer disease
CONCLUSION: Spatial memory performance, hippocampal neurodegeneration, and serum levels of miR-let-7b and miR-181c were affected by MFB-ICSS under AD-like conditions. Our results validate the MFB as a potential target for DBS and lend support to the use of specific miRNAs as promising biomarkers of the effectiveness of DBS in combatting AD-associated cognitive deficits.PMID:38490646 | DOI:10.1503/jpn.230066 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - March 15, 2024 Category: Psychiatry Authors: Andrea Riberas-S ánchez Irene Puig-Parnau Laia Vila-Sol és Soleil Garcia-Brito Laura Aldavert-Vera Pilar Segura-Torres Gemma Huguet Elisabet K ádár Source Type: research
Intracranial self-stimulation reverses impaired spatial learning and regulates serum microRNA levels in a streptozotocin-induced rat model of Alzheimer disease
CONCLUSION: Spatial memory performance, hippocampal neurodegeneration, and serum levels of miR-let-7b and miR-181c were affected by MFB-ICSS under AD-like conditions. Our results validate the MFB as a potential target for DBS and lend support to the use of specific miRNAs as promising biomarkers of the effectiveness of DBS in combatting AD-associated cognitive deficits.PMID:38490646 | DOI:10.1503/jpn.230066 (Source: J Psychiatry Neurosc...)
Source: J Psychiatry Neurosc... - March 15, 2024 Category: Psychiatry Authors: Andrea Riberas-S ánchez Irene Puig-Parnau Laia Vila-Sol és Soleil Garcia-Brito Laura Aldavert-Vera Pilar Segura-Torres Gemma Huguet Elisabet K ádár Source Type: research
Intracranial self-stimulation reverses impaired spatial learning and regulates serum microRNA levels in a streptozotocin-induced rat model of Alzheimer disease
CONCLUSION: Spatial memory performance, hippocampal neurodegeneration, and serum levels of miR-let-7b and miR-181c were affected by MFB-ICSS under AD-like conditions. Our results validate the MFB as a potential target for DBS and lend support to the use of specific miRNAs as promising biomarkers of the effectiveness of DBS in combatting AD-associated cognitive deficits.PMID:38490646 | DOI:10.1503/jpn.230066 (Source: J Psychiatry Neurosc...)
Source: J Psychiatry Neurosc... - March 15, 2024 Category: Psychiatry Authors: Andrea Riberas-S ánchez Irene Puig-Parnau Laia Vila-Sol és Soleil Garcia-Brito Laura Aldavert-Vera Pilar Segura-Torres Gemma Huguet Elisabet K ádár Source Type: research
Intracranial self-stimulation reverses impaired spatial learning and regulates serum microRNA levels in a streptozotocin-induced rat model of Alzheimer disease
CONCLUSION: Spatial memory performance, hippocampal neurodegeneration, and serum levels of miR-let-7b and miR-181c were affected by MFB-ICSS under AD-like conditions. Our results validate the MFB as a potential target for DBS and lend support to the use of specific miRNAs as promising biomarkers of the effectiveness of DBS in combatting AD-associated cognitive deficits.PMID:38490646 | DOI:10.1503/jpn.230066 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - March 15, 2024 Category: Psychiatry Authors: Andrea Riberas-S ánchez Irene Puig-Parnau Laia Vila-Sol és Soleil Garcia-Brito Laura Aldavert-Vera Pilar Segura-Torres Gemma Huguet Elisabet K ádár Source Type: research
Topographical anatomy of the subthalamic region with special interest in the human medial forebrain bundle
CONCLUSIONS: According to this study's findings, the streamlines of the MFB described by tractography arise from the limitations of the diffusion-weighted MRI fiber tracking method and actually correspond to subthalamic fiber bundles, especially the ansa lenticularis and lenticular fasciculus, which erroneously continue in the anterior limb of the internal capsule, toward the prefrontal cortex.PMID:38489821 | DOI:10.3171/2024.1.JNS232066 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 15, 2024 Category: Neurosurgery Authors: Cintia Meszaros Peter Kurucz Gabor Baksa Alan Alpar Oliver Ganslandt Sebastian Brandner Laszlo Barany Source Type: research
Clinical evaluation of a stereotactic system for single-stage deep brain stimulation surgery under general anesthesia: technical note
CONCLUSIONS: The stereotactic system facilitated safe and effective asleep, single-stage DBS surgery, maintaining traditional lead accuracy standards.PMID:38489816 | DOI:10.3171/2024.1.JNS232563 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 15, 2024 Category: Neurosurgery Authors: Kristen M Scheitler Aaron E Rusheen Jason Yuen Abhinav Goyal Sukwoo Hong Gamaleldin M Osman Basel Sharaf Bryan T Klassen Sanjeet S Grewal Kai J Miller Hojin Shin Yoonbae Oh Kendall H Lee Source Type: research
Intracranial self-stimulation reverses impaired spatial learning and regulates serum microRNA levels in a streptozotocin-induced rat model of Alzheimer disease
CONCLUSION: Spatial memory performance, hippocampal neurodegeneration, and serum levels of miR-let-7b and miR-181c were affected by MFB-ICSS under AD-like conditions. Our results validate the MFB as a potential target for DBS and lend support to the use of specific miRNAs as promising biomarkers of the effectiveness of DBS in combatting AD-associated cognitive deficits.PMID:38490646 | PMC:PMC10950362 | DOI:10.1503/jpn.230066 (Source: J Psychiatry Neurosc...)
Source: J Psychiatry Neurosc... - March 15, 2024 Category: Psychiatry Authors: Andrea Riberas-S ánchez Irene Puig-Parnau Laia Vila-Sol és Soleil Garcia-Brito Laura Aldavert-Vera Pilar Segura-Torres Gemma Huguet Elisabet K ádár Source Type: research
Intracranial self-stimulation reverses impaired spatial learning and regulates serum microRNA levels in a streptozotocin-induced rat model of Alzheimer disease
CONCLUSION: Spatial memory performance, hippocampal neurodegeneration, and serum levels of miR-let-7b and miR-181c were affected by MFB-ICSS under AD-like conditions. Our results validate the MFB as a potential target for DBS and lend support to the use of specific miRNAs as promising biomarkers of the effectiveness of DBS in combatting AD-associated cognitive deficits.PMID:38490646 | PMC:PMC10950362 | DOI:10.1503/jpn.230066 (Source: Journal of Psychiatry and Neuroscience)
Source: Journal of Psychiatry and Neuroscience - March 15, 2024 Category: Psychiatry Authors: Andrea Riberas-S ánchez Irene Puig-Parnau Laia Vila-Sol és Soleil Garcia-Brito Laura Aldavert-Vera Pilar Segura-Torres Gemma Huguet Elisabet K ádár Source Type: research
Clinical evaluation of a stereotactic system for single-stage deep brain stimulation surgery under general anesthesia: technical note
CONCLUSIONS: The stereotactic system facilitated safe and effective asleep, single-stage DBS surgery, maintaining traditional lead accuracy standards.PMID:38489816 | DOI:10.3171/2024.1.JNS232563 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 15, 2024 Category: Neurosurgery Authors: Kristen M Scheitler Aaron E Rusheen Jason Yuen Abhinav Goyal Sukwoo Hong Gamaleldin M Osman Basel Sharaf Bryan T Klassen Sanjeet S Grewal Kai J Miller Hojin Shin Yoonbae Oh Kendall H Lee Source Type: research
Topographical anatomy of the subthalamic region with special interest in the human medial forebrain bundle
CONCLUSIONS: According to this study's findings, the streamlines of the MFB described by tractography arise from the limitations of the diffusion-weighted MRI fiber tracking method and actually correspond to subthalamic fiber bundles, especially the ansa lenticularis and lenticular fasciculus, which erroneously continue in the anterior limb of the internal capsule, toward the prefrontal cortex.PMID:38489821 | DOI:10.3171/2024.1.JNS232066 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 15, 2024 Category: Neurosurgery Authors: Cintia Meszaros Peter Kurucz Gabor Baksa Alan Alpar Oliver Ganslandt Sebastian Brandner Laszlo Barany Source Type: research
