Hospitalizations in Adult Patients With Congenital Heart Disease in Japan
Circ J. 2023 Dec 1. doi: 10.1253/circj.CJ-23-0822. Online ahead of print.NO ABSTRACTPMID:38044146 | DOI:10.1253/circj.CJ-23-0822 (Source: Circulation Journal)
Source: Circulation Journal - December 3, 2023 Category: Cardiology Authors: Katsura Soma Atsushi Yao Source Type: research
Hospitalizations in Adult Patients With Congenital Heart Disease in Japan
Circ J. 2023 Dec 1. doi: 10.1253/circj.CJ-23-0822. Online ahead of print.NO ABSTRACTPMID:38044146 | DOI:10.1253/circj.CJ-23-0822 (Source: Circulation Journal)
Source: Circulation Journal - December 3, 2023 Category: Cardiology Authors: Katsura Soma Atsushi Yao Source Type: research
Late Toxicity of Prostate Ultrahypofractionated Radiotherapy Compared to Moderate Hypofractionation in a Randomized Trial
CONCLUSION: UHF, delivered weekly, is well tolerated with no significant differences in freedom from late toxicity compared to MHF.PMID:38042451 | DOI:10.1016/j.ijrobp.2023.11.048 (Source: Health Physics)
Source: Health Physics - December 2, 2023 Category: Physics Authors: Abraham Alexander Isabelle Gagne Gaurav Bahl David Kim Ante Mestrovic Allison Ye Winkle Kwan Samar Hejazi Source Type: research
Molecules, Vol. 28, Pages 7909: Are There Lipid Membrane-Domain Subtypes in Neurons with Different Roles in Calcium Signaling?
z-Merino
Lipid membrane nanodomains or lipid rafts are 10–200 nm diameter size cholesterol- and sphingolipid-enriched domains of the plasma membrane, gathering many proteins with different roles. Isolation and characterization of plasma membrane proteins by differential centrifugation and proteomic studies have revealed a remarkable diversity of proteins in these domains. The limited size of the lipid membrane nanodomain challenges the simple possibility that all of them can coexist within the same lipid membrane domain. As caveolin-1, flotillin isoforms and gangliosides are currently used as neuronal lip...
Source: Molecules - December 2, 2023 Category: Chemistry Authors: Alejandro K. Samhan-Arias Joana Poejo Dorinda Marques-da-Silva Oscar H. Mart ínez-Costa Carlos Gutierrez-Merino Tags: Review Source Type: research
The ultrastructure of macaque mesencephalic trigeminal nucleus neurons
In this study, we explored the ultrastructure of macaque mesencephalic trigeminal nucleus neurons to determine the presence and nature of this synaptic input in a primate. We first confirmed the location of macaque mesencephalic trigeminal neurons by retrograde labeling from the masticatory muscles. Since the labeled neurons were by far the largest cells located at the edge of the periaqueductal gray, we could undertake sampling for electron microscopy based on soma size. Ultrastructurally, mesencephalic trigeminal neurons had very large somata with euchromatic nuclei that sometimes displayed deeply indented nuclear membra...
Source: Brain Research - December 1, 2023 Category: Neurology Authors: Niping Wang Paul J May Source Type: research
The ultrastructure of macaque mesencephalic trigeminal nucleus neurons
In this study, we explored the ultrastructure of macaque mesencephalic trigeminal nucleus neurons to determine the presence and nature of this synaptic input in a primate. We first confirmed the location of macaque mesencephalic trigeminal neurons by retrograde labeling from the masticatory muscles. Since the labeled neurons were by far the largest cells located at the edge of the periaqueductal gray, we could undertake sampling for electron microscopy based on soma size. Ultrastructurally, mesencephalic trigeminal neurons had very large somata with euchromatic nuclei that sometimes displayed deeply indented nuclear membra...
Source: Experimental Brain Research - December 1, 2023 Category: Neuroscience Authors: Niping Wang Paul J May Source Type: research
The ultrastructure of macaque mesencephalic trigeminal nucleus neurons
In this study, we explored the ultrastructure of macaque mesencephalic trigeminal nucleus neurons to determine the presence and nature of this synaptic input in a primate. We first confirmed the location of macaque mesencephalic trigeminal neurons by retrograde labeling from the masticatory muscles. Since the labeled neurons were by far the largest cells located at the edge of the periaqueductal gray, we could undertake sampling for electron microscopy based on soma size. Ultrastructurally, mesencephalic trigeminal neurons had very large somata with euchromatic nuclei that sometimes displayed deeply indented nuclear membra...
Source: Cell Research - December 1, 2023 Category: Cytology Authors: Niping Wang Paul J May Source Type: research
The ultrastructure of macaque mesencephalic trigeminal nucleus neurons
In this study, we explored the ultrastructure of macaque mesencephalic trigeminal nucleus neurons to determine the presence and nature of this synaptic input in a primate. We first confirmed the location of macaque mesencephalic trigeminal neurons by retrograde labeling from the masticatory muscles. Since the labeled neurons were by far the largest cells located at the edge of the periaqueductal gray, we could undertake sampling for electron microscopy based on soma size. Ultrastructurally, mesencephalic trigeminal neurons had very large somata with euchromatic nuclei that sometimes displayed deeply indented nuclear membra...
Source: Brain Research - December 1, 2023 Category: Neurology Authors: Niping Wang Paul J May Source Type: research
The ultrastructure of macaque mesencephalic trigeminal nucleus neurons
In this study, we explored the ultrastructure of macaque mesencephalic trigeminal nucleus neurons to determine the presence and nature of this synaptic input in a primate. We first confirmed the location of macaque mesencephalic trigeminal neurons by retrograde labeling from the masticatory muscles. Since the labeled neurons were by far the largest cells located at the edge of the periaqueductal gray, we could undertake sampling for electron microscopy based on soma size. Ultrastructurally, mesencephalic trigeminal neurons had very large somata with euchromatic nuclei that sometimes displayed deeply indented nuclear membra...
Source: Experimental Brain Research - December 1, 2023 Category: Neuroscience Authors: Niping Wang Paul J May Source Type: research
The ultrastructure of macaque mesencephalic trigeminal nucleus neurons
In this study, we explored the ultrastructure of macaque mesencephalic trigeminal nucleus neurons to determine the presence and nature of this synaptic input in a primate. We first confirmed the location of macaque mesencephalic trigeminal neurons by retrograde labeling from the masticatory muscles. Since the labeled neurons were by far the largest cells located at the edge of the periaqueductal gray, we could undertake sampling for electron microscopy based on soma size. Ultrastructurally, mesencephalic trigeminal neurons had very large somata with euchromatic nuclei that sometimes displayed deeply indented nuclear membra...
Source: Experimental Brain Research - December 1, 2023 Category: Neuroscience Authors: Niping Wang Paul J May Source Type: research
The ultrastructure of macaque mesencephalic trigeminal nucleus neurons
In this study, we explored the ultrastructure of macaque mesencephalic trigeminal nucleus neurons to determine the presence and nature of this synaptic input in a primate. We first confirmed the location of macaque mesencephalic trigeminal neurons by retrograde labeling from the masticatory muscles. Since the labeled neurons were by far the largest cells located at the edge of the periaqueductal gray, we could undertake sampling for electron microscopy based on soma size. Ultrastructurally, mesencephalic trigeminal neurons had very large somata with euchromatic nuclei that sometimes displayed deeply indented nuclear membra...
Source: Experimental Brain Research - December 1, 2023 Category: Neuroscience Authors: Niping Wang Paul J May Source Type: research
GSE248602 Next Generation Sequencing and Quantitative Analysis of mRNAs in Caenorhabditis elegans fbxl-5 Mutant Animals
Contributor : Robert H DowenSeries Type : Expression profiling by high throughput sequencingOrganism : Caenorhabditis elegansThe molecular mechanisms that govern the metabolic commitment to reproduction, which often occurs at the expense of the soma, remain poorly understood. We identified the C. elegans F-box protein FBXL-5 as a negative regulator of maternal provisioning of vitellogenin lipoproteins, which mediate the transfer of intestinal lipids to the germline. Mutations in fbxl-5 partially suppress the vitellogenesis defects observed in the heterochronic mutants lin-4 and lin-29, both of which ectopically express fbx...
Source: GEO: Gene Expression Omnibus - December 1, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Caenorhabditis elegans Source Type: research
Microglia-neuron interactions in prefrontal gray matter in schizophrenia: a postmortem ultrastructural morphometric study
This study addressed the question of whether the interaction between neurons and satellite microglia (SatMg) is abnormal in schizophrenia. SatMg-neuron communication at direct contacts between neuronal soma is essential for neuroplasticity as SatMg can regulate neuronal activity. A postmortem ultrastructural morphometric study was performed to investigate SatMg and adjacent neurons in layer 5 of the prefrontal cortex in 21 cases of schizophrenia and 20 healthy controls. Density of SatMg was significantly higher in the young schizophrenia group and in the group with illness duration ≤ 26 years as compared to control...
Source: European Archives of Psychiatry and Clinical Neuroscience - December 1, 2023 Category: Neuroscience Source Type: research
Chaetocin-mediated SUV39H1 inhibition targets stemness and oncogenic networks of diffuse midline gliomas and synergizes with ONC201
CONCLUSIONS: Our studies reveal a therapeutic vulnerability of DIPG cells through targeting the SUV39H1-H3K9me3 pathway and compensatory signaling loops for treating this devastating disease. Combining SUV39H1-targeting chaetocin with other agents such as ONC201 may offer a new strategy for effective DIPG treatment.PMID:38011799 | DOI:10.1093/neuonc/noad222 (Source: Ann Oncol)
Source: Ann Oncol - November 27, 2023 Category: Cancer & Oncology Authors: Dazhuan Eric Xin Yunfei Liao Rohit Rao Sean Ogurek Soma Sengupta Mei Xin William L Seibel Richard T Graham Carl Koschmann Q Richard Lu Source Type: research
Mosquito (Diptera: Culicidae) populations in contrasting areas of the western regions of Burkina Faso: species diversity, abundance and their implications for pathogen transmission
Mosquitoes (Diptera: Culicidae) can have a significant negative impact on human health. The urbanization of natural environments and their conversion for agricultural use, as well as human population growth, m... (Source: Parasites and Vectors)
Source: Parasites and Vectors - November 27, 2023 Category: Microbiology Authors: Didier P. Alexandre Kabor é, Dieudonné Diloma Soma, Patricia Gil, Mahamadi Kientega, Simon P. Sawadogo, Georges Anicet Ouédraogo, Philippe Van de Perre, Thierry Baldet, Serafin Gutierrez and Roch K. Dabiré Tags: Research Source Type: research
