Transient expression of heavy-chain neurofilaments in the perigeniculate nucleus of cats
This study focused on the postnatal development of the PGN in cats, using the SMI-32 antibody, which recognizes non-phosphorylated heavy-chain neurofilaments responsible for neuronal structural maturation and is also used as a marker for motion processing, or Y, stream. We questioned whether transient neuronal populations exist in the PGN and can they possibly be related to the Y processing stream. We uncovered a transient, robust SMI-32 staining in the PGN of kittens aged 0-34 days with the significant decline in the cellular density of labeled cells in older animals. According to the double-labeling, in all examined age ...
Source: Brain Structure and Function - January 24, 2024 Category: Neuroscience Authors: Natalia Merkulyeva Aleksandr Mikhalkin Source Type: research
Transient expression of heavy-chain neurofilaments in the perigeniculate nucleus of cats
This study focused on the postnatal development of the PGN in cats, using the SMI-32 antibody, which recognizes non-phosphorylated heavy-chain neurofilaments responsible for neuronal structural maturation and is also used as a marker for motion processing, or Y, stream. We questioned whether transient neuronal populations exist in the PGN and can they possibly be related to the Y processing stream. We uncovered a transient, robust SMI-32 staining in the PGN of kittens aged 0 –34 days with the significant decline in the cellular density of labeled cells in older animals. According to the double-labeling, in all examined ...
Source: Anatomy and Embryology - January 24, 2024 Category: Anatomy Source Type: research
Rationalized diffraction calculations for high accuracy and high speed with few bits
Diffraction calculations in few-bit formats, such as single-precision floating-point and fixed-point numbers, are important because they ... (Source: Journal of the Optical Society of America A)
Source: Journal of the Optical Society of America A - January 23, 2024 Category: Physics Authors: Soma Fujimori Tomoyoshi Ito Tomoyoshi Shimobaba Source Type: research
Improving the quality of counseling and clinical supervision in opioid treatment programs: how can technology help?
CONCLUSIONS: Implementing evidence-based counseling practices can help the population served in OTPs; another benefit of focusing on clinical skills is to emphasize and hold up counselors' roles as worthy. Machine learning technology can have a positive impact on clinical practices among counselors and clinical supervisors in opioid treatment programs, settings whose clinical workforce continues to be challenged by the opioid epidemic. Using technology to focus on clinical skill building may enhance counselors' and clinical supervisors' overall experiences in their places of work.PMID:38245783 | PMC:PMC10799386 | DOI:10.11...
Source: Addiction Science and Clinical Practice - January 20, 2024 Category: Addiction Authors: K Michelle Peavy Angela Klipsch Christina S Soma Brian Pace Zac E Imel Michael J Tanana Sean Soth Esther Ricardo-Bulis David C Atkins Source Type: research
Public knowledge and beliefs about the irritable bowel syndrome - results from the SOMA.SOC study
Despite the epidemiological and economic relevance of the irritable bowel syndrome (IBS), there is a lack of research on what the general public knows and thinks about this condition (IBS literacy). Therefore,... (Source: BMC Public Health)
Source: BMC Public Health - January 18, 2024 Category: Consumer Health News Authors: Olaf von dem Knesebeck, Bernd L öwe, Daniel Lüdecke, Johanna S. Bobardt and Rieke Barbek Tags: Research Source Type: research
Exosomal DNA: an alternative vehicle for soma-to-germline communication?
J Physiol. 2024 Jan 15. doi: 10.1113/JP286170. Online ahead of print.NO ABSTRACTPMID:38224265 | DOI:10.1113/JP286170 (Source: The Journal of Physiology)
Source: The Journal of Physiology - January 15, 2024 Category: Physiology Authors: Haili Sun Yongsheng Liu Source Type: research
Biofilm-producing antibiotic-resistant bacteria in Indian patients: a comprehensive review
Curr Med Res Opin. 2024 Jan 12:1-20. doi: 10.1080/03007995.2024.2305241. Online ahead of print.ABSTRACTFor the past few years, microbial biofilms have been emerging as a significant threat to the modern healthcare system, and their prevalence and antibiotic resistance threat gradually increase daily among the human population. The biofilm has a remarkable impact in the field of infectious diseases, in particular healthcare-associated infections related to indwelling devices such as catheters, implants, artificial heart valves, and prosthetic joints. Bacterial biofilm potentially adheres to any biotic or abiotic surfaces th...
Source: Current Medical Research and Opinion - January 12, 2024 Category: Research Authors: Susmita Datta Soma Nag Dijendra Nath Roy Source Type: research
Growth and longevity modulation through larval environment mediate immunosenescence and immune strategy of Tenebrio molitor
The Disposable Soma Theory of aging suggests a trade-off between energy allocation for growth, reproduction and somatic maintenance, including immunity. While trade-offs between reproduction and immunity are w... (Source: Immunity and Aging)
Source: Immunity and Aging - January 12, 2024 Category: Geriatrics Authors: Agathe Crosland, Thierry Rigaud, Charl ène Develay and Yannick Moret Tags: Research Source Type: research
Chronic chemogenetic inhibition of TRPV1 bladder afferent promotes micturition recovery post SCI
Exp Neurol. 2024 Jan 8;374:114686. doi: 10.1016/j.expneurol.2024.114686. Online ahead of print.ABSTRACTSpinal cord injury often results in chronic loss of micturition control, which is featured by bladder hyperreflexia and detrusor sphincter dyssynergia. Previous studies showed that treatment of capsaicin reduces non-voiding bladder contractions in multiple animal injury models and human patients. However, its underlying neural mechanisms remain largely unknown. Here, by injecting a RetroAAV into the bladder wall, we specifically targeted TRPV1+, a capsaicin receptor, bladder afferent neurons. Morphometric analysis reveale...
Source: Experimental Neurology - January 10, 2024 Category: Neurology Authors: Long Ma Chen Zhu Yun-Fei Wei Jin-Yong Zhou Min Chen Xin Zhang Ping Zhou Yan Wang Jian Wang Can Chu Jing-Yuan Tang Yan Xu Source Type: research
Effects of Online Mindful Somatic Psychoeducation Program on Mental Health During the COVID-19
CONCLUSION: The o-MSP effectively reduced stress and anxiety in female university students and improved social connectedness. This suggests that o-MSP can be used to manage the mental health of university students in various settings.PMID:38198829 | PMC:PMC10822736 | DOI:10.30773/pi.2023.0304 (Source: Psychiatry Investigation)
Source: Psychiatry Investigation - January 10, 2024 Category: Psychiatry Authors: Young Sook Yook Jae-Hon Lee Inkyoung Park Hwi-Young Cho Source Type: research
piOxi database: a web resource of germline and somatic tissue piRNAs identified by chemical oxidation
AbstractPIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs that are highly expressed and extensively studied from the germline. piRNAs associate with PIWI proteins to maintain DNA methylation for transposon silencing and transcriptional gene regulation for genomic stability. Mature germline piRNAs have distinct characteristics including a 24- to 32-nucleotide length and a 2 ʹ-O-methylation signature at the 3ʹ end. Although recent studies have identified piRNAs in somatic tissues, they remain poorly characterized. For example, we recently demonstrated notable expression of piRNA in the murine soma, and wh...
Source: Database : The Journal of Biological Databases and Curation - January 10, 2024 Category: Databases & Libraries Source Type: research
GSE223253 Autonomous transposons tune their sequences to ensure somatic suppression [FLASH]
Contributors : Ibrahin A Ilik ; Petar Gla žar ; Tugce AktasSeries Type : OtherOrganism : Drosophila melanogaster ; Homo sapiens ; Mus musculusTransposable elements (TEs) are a major constituent of human genes, occupying approximately half of the intronic space. During pre-mRNA synthesis, intronic TEs are transcribed along with their host genes but rarely contribute to the final mRNA product as they are spliced out together with the intron and rapidly degraded. Paradoxically, TEs are an abundant source of RNA-processing signals through which they can create new introns (Huff et al. 2016), and functional (Cosby et al. 202...
Source: GEO: Gene Expression Omnibus - January 8, 2024 Category: Genetics & Stem Cells Tags: Other Drosophila melanogaster Homo sapiens Mus musculus Source Type: research
GSE223254 Autonomous transposons tune their sequences to ensure somatic suppression [polyA_3T3]
Contributors : Ibrahim A Ilik ; Petar Gla žar ; Tugce AktasSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTransposable elements (TEs) are a major constituent of human genes, occupying approximately half of the intronic space. During pre-mRNA synthesis, intron Łic TEs are transcribed along with their host genes but rarely contribute to the final mRNA product as they are spliced out together with the intron and rapidly degraded. Paradoxically, TEs are an abundant source of RNA-processing signals through which they can create new introns (Huff et al. 2016) , and functional (Cosby et...
Source: GEO: Gene Expression Omnibus - January 8, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
GSE223257 Autonomous transposons tune their sequences to ensure somatic suppression [polyA_HEK293]
Contributors : Ibrahim A Ilik ; Petar Gla žar ; Tugce AktasSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTransposable elements (TEs) are a major constituent of human genes, occupying approximately half of the intronic space. During pre-mRNA synthesis, intronic TEs are transcribed along with their host genes but rarely contribute to the final mRNA product as they are spliced out together with the intron and rapidly degraded. Paradoxically, TEs are an abundant source of RNA-processing signals through which they can create new introns (Huff et al. 2016), and functional (Cosby et al....
Source: GEO: Gene Expression Omnibus - January 8, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
