Properties of the Caudal Pontine Reticular Nucleus Neurons Determine the Acoustic Startle Response in < em > Cntnap2 < /em > KO Rats
CONCLUSIONS: Recruitment and size of PnC giant neurons are important factors for regulating the magnitude of the acoustic startle response in Cntnap2-⁣/- rats, particularly in males. These findings allow for a better understanding of increased reactivity to sound in Cntnap2-⁣/- rats and in CNTNAP2-associated disorders such as ASD.PMID:38538232 | DOI:10.31083/j.jin2303063 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - March 27, 2024 Category: Neuroscience Authors: Alice Zheng Rajkamalpreet S Mann Dami Solaja Brian L Allman Susanne Schmid Source Type: research

Properties of the Caudal Pontine Reticular Nucleus Neurons Determine the Acoustic Startle Response in < em > Cntnap2 < /em > KO Rats
CONCLUSIONS: Recruitment and size of PnC giant neurons are important factors for regulating the magnitude of the acoustic startle response in Cntnap2-⁣/- rats, particularly in males. These findings allow for a better understanding of increased reactivity to sound in Cntnap2-⁣/- rats and in CNTNAP2-associated disorders such as ASD.PMID:38538232 | DOI:10.31083/j.jin2303063 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - March 27, 2024 Category: Neuroscience Authors: Alice Zheng Rajkamalpreet S Mann Dami Solaja Brian L Allman Susanne Schmid Source Type: research

Properties of the Caudal Pontine Reticular Nucleus Neurons Determine the Acoustic Startle Response in < em > Cntnap2 < /em > KO Rats
CONCLUSIONS: Recruitment and size of PnC giant neurons are important factors for regulating the magnitude of the acoustic startle response in Cntnap2-⁣/- rats, particularly in males. These findings allow for a better understanding of increased reactivity to sound in Cntnap2-⁣/- rats and in CNTNAP2-associated disorders such as ASD.PMID:38538232 | DOI:10.31083/j.jin2303063 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - March 27, 2024 Category: Neuroscience Authors: Alice Zheng Rajkamalpreet S Mann Dami Solaja Brian L Allman Susanne Schmid Source Type: research

Properties of the Caudal Pontine Reticular Nucleus Neurons Determine the Acoustic Startle Response in < em > Cntnap2 < /em > KO Rats
CONCLUSIONS: Recruitment and size of PnC giant neurons are important factors for regulating the magnitude of the acoustic startle response in Cntnap2-⁣/- rats, particularly in males. These findings allow for a better understanding of increased reactivity to sound in Cntnap2-⁣/- rats and in CNTNAP2-associated disorders such as ASD.PMID:38538232 | DOI:10.31083/j.jin2303063 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - March 27, 2024 Category: Neuroscience Authors: Alice Zheng Rajkamalpreet S Mann Dami Solaja Brian L Allman Susanne Schmid Source Type: research

Properties of the Caudal Pontine Reticular Nucleus Neurons Determine the Acoustic Startle Response in < em > Cntnap2 < /em > KO Rats
CONCLUSIONS: Recruitment and size of PnC giant neurons are important factors for regulating the magnitude of the acoustic startle response in Cntnap2-⁣/- rats, particularly in males. These findings allow for a better understanding of increased reactivity to sound in Cntnap2-⁣/- rats and in CNTNAP2-associated disorders such as ASD.PMID:38538232 | DOI:10.31083/j.jin2303063 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - March 27, 2024 Category: Neuroscience Authors: Alice Zheng Rajkamalpreet S Mann Dami Solaja Brian L Allman Susanne Schmid Source Type: research

Properties of the Caudal Pontine Reticular Nucleus Neurons Determine the Acoustic Startle Response in < em > Cntnap2 < /em > KO Rats
CONCLUSIONS: Recruitment and size of PnC giant neurons are important factors for regulating the magnitude of the acoustic startle response in Cntnap2-⁣/- rats, particularly in males. These findings allow for a better understanding of increased reactivity to sound in Cntnap2-⁣/- rats and in CNTNAP2-associated disorders such as ASD.PMID:38538232 | DOI:10.31083/j.jin2303063 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - March 27, 2024 Category: Neuroscience Authors: Alice Zheng Rajkamalpreet S Mann Dami Solaja Brian L Allman Susanne Schmid Source Type: research

Properties of the Caudal Pontine Reticular Nucleus Neurons Determine the Acoustic Startle Response in < em > Cntnap2 < /em > KO Rats
CONCLUSIONS: Recruitment and size of PnC giant neurons are important factors for regulating the magnitude of the acoustic startle response in Cntnap2-⁣/- rats, particularly in males. These findings allow for a better understanding of increased reactivity to sound in Cntnap2-⁣/- rats and in CNTNAP2-associated disorders such as ASD.PMID:38538232 | DOI:10.31083/j.jin2303063 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - March 27, 2024 Category: Neuroscience Authors: Alice Zheng Rajkamalpreet S Mann Dami Solaja Brian L Allman Susanne Schmid Source Type: research

Properties of the Caudal Pontine Reticular Nucleus Neurons Determine the Acoustic Startle Response in < em > Cntnap2 < /em > KO Rats
CONCLUSIONS: Recruitment and size of PnC giant neurons are important factors for regulating the magnitude of the acoustic startle response in Cntnap2-⁣/- rats, particularly in males. These findings allow for a better understanding of increased reactivity to sound in Cntnap2-⁣/- rats and in CNTNAP2-associated disorders such as ASD.PMID:38538232 | DOI:10.31083/j.jin2303063 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - March 27, 2024 Category: Neuroscience Authors: Alice Zheng Rajkamalpreet S Mann Dami Solaja Brian L Allman Susanne Schmid Source Type: research

Properties of the Caudal Pontine Reticular Nucleus Neurons Determine the Acoustic Startle Response in < em > Cntnap2 < /em > KO Rats
CONCLUSIONS: Recruitment and size of PnC giant neurons are important factors for regulating the magnitude of the acoustic startle response in Cntnap2-⁣/- rats, particularly in males. These findings allow for a better understanding of increased reactivity to sound in Cntnap2-⁣/- rats and in CNTNAP2-associated disorders such as ASD.PMID:38538232 | DOI:10.31083/j.jin2303063 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - March 27, 2024 Category: Neuroscience Authors: Alice Zheng Rajkamalpreet S Mann Dami Solaja Brian L Allman Susanne Schmid Source Type: research

Properties of the Caudal Pontine Reticular Nucleus Neurons Determine the Acoustic Startle Response in < em > Cntnap2 < /em > KO Rats
CONCLUSIONS: Recruitment and size of PnC giant neurons are important factors for regulating the magnitude of the acoustic startle response in Cntnap2-⁣/- rats, particularly in males. These findings allow for a better understanding of increased reactivity to sound in Cntnap2-⁣/- rats and in CNTNAP2-associated disorders such as ASD.PMID:38538232 | DOI:10.31083/j.jin2303063 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - March 27, 2024 Category: Neuroscience Authors: Alice Zheng Rajkamalpreet S Mann Dami Solaja Brian L Allman Susanne Schmid Source Type: research

A Phase 0/1 Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination with Standard Therapy in Recurrent High-Grade Gliomas
CONCLUSION: Based on safety, brain tumoral PK, and mechanistic data, 15 mg daily is identified as the RP2D for future trials.PMID:38530160 | DOI:10.1158/1078-0432.CCR-23-3341 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - March 26, 2024 Category: Cancer & Oncology Authors: Pankaj B Desai Aniruddha Karve Misam Zawit Priyanka Arora Nimita Dave Joy Awosika Ningjing Li Bethany Fuhrman Mario Medvedovic Larry Sallans Ady Kendler Biplab DasGupta David Plas Richard Curry Mario Zuccarello Rekha Chaudhary Soma Sengupta Trisha M Wise- Source Type: research

Response to 'Commentary on the published position statement regarding the pathogenesis of fetal basal ganglia- thalamic hypoxic-ischaemic injury' (Anthony et al.)
S Afr Med J. 2023 Dec 31;114(1):10-12. doi: 10.7196/SAMJ.2024.v114i1.1844.NO ABSTRACTPMID:38525610 | DOI:10.7196/SAMJ.2024.v114i1.1844 (Source: South African Medical Journal)
Source: South African Medical Journal - March 25, 2024 Category: African Health Authors: I Bhorat E Buchmann K Frank P Soma-Pillay E Nicolaou L Pistorius I Smuts Source Type: research