Will global warming undo the hard-won gains of prevention of mother-to-child transmission of HIV?
Authors: Chersich M PMID: 31131789 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

South Africa's first national vaccination coverage survey since 1994.
Authors: Burnett RJ, Dlamini NR, Meyer JC, Mutevedzi P, Kibuuka DK, Mphahlele MJ, Madhi SA Abstract PMID: 31131790 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Refusal by surgical registrars to administer or recommend blood transfusions for religious reasons.
Authors: McQuoid-Mason DJ Abstract PMID: 31131791 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Why South Africa urgently needs to support the development of pregnancy exposure registries.
Authors: Mehta U, Kalk E, Fairlie L, Boulle A, Rees H PMID: 31131792 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Life-threatening Listeria meningitis: Need for revision of South African acute bacterial meningitis treatment guidelines.
CONCLUSIONS: Our two cases demonstrate that the listeriosis outbreak should change the way we view bacterial meningitis in SA: according to the National Institute for Communicable Diseases, empirical treatment for meningitis should include ampicillin and gentamicin in all adult patients with features of meningitis. There may be a need for an updated meningitis treatment guideline in SA. PMID: 31131793 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Measuring quality outcomes across hospital systems: Using a claims data model for risk adjustment of mortality rates.
This article describes and evaluates the validity of risk-adjustment methods applied to service claims data to accurately determine SMRs across hospital systems. While service claims data may have limitations regarding case risk adjustment, it is important that we do not lose the important opportunity to use claims data as a reliable proxy to comment on the quality of care within healthcare systems. This methodology is robust in its demonstration of variation of performance on mortality outcomes across hospital systems. For the measurement period January 2014 - December 2016, the average risk-adjusted SMRs across hospital ...
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Asthma treatment in children: A guide to screening for and management of hypothalamic-pituitary-adrenal axis suppression.
Authors: Zöllner EW Abstract A recently published approach to paediatric asthma management neither recommended screening for nor suggested any management of hypothalamic-pituitary-adrenal axis suppression in asthmatic children treated with corticosteroids. The existing literature on this topic was therefore reviewed and the quality of the evidence assessed. Recommendations for diagnosis, screening and management are made utilising the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. PMID: 31131795 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Tuberculosis transmission in a hospitalised neonate: Need for optimised tuberculosis screening of pregnant and postpartum women.
We describe the subsequent process of tracing other TB-exposed infants and mothers, the difficulty in confirming TB infection/disease in pregnancy, and the provision of isoniazid preventive therapy in this cohort. We discuss the practical implementation of TB screening approaches in maternity and neonatal wards in high-burden TB settings. PMID: 31131796 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Hepatitis A seroprevalence in Western Cape Province, South Africa: Are we in epidemiological transition?
CONCLUSIONS: These results suggest an urgent need for detailed evidence-based considerations to introduce hepatitis A vaccine into the EPI-SA. PMID: 31131797 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Immunisation after hepatitis B polyvalent vaccination among children in South Kivu Province, Democratic Republic of the Congo.
CONCLUSIONS: The study demonstrated that the rate of seroprotection in the current vaccination programme against HBV in DRC was lower than desirable but comparable to rates reported in some other African countries. Further studies are needed to assess this finding and to evaluate ways to optimise the seroprotection rate. PMID: 31131798 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Acquisition of tolerance to egg and peanut in African food-allergic children with atopic dermatitis.
CONCLUSIONS: Egg allergy was outgrown in 72.2% and peanut allergy in 15.8% of SA children 5 years after diagnosis of AD. This is in keeping with findings derived from studies in higher socioeconomic settings, and can help to guide the counselling of patients with allergies to these foods of high nutritional value. PMID: 31131799 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Evidence for high sugar content of baby foods in South Africa.
CONCLUSIONS: The SA baby food market is characterised by products with a high sugar content, promoting an environment that encourages development of sweet-taste preferences and in the long term contributing to the rising burden of NCDs. There is an urgent need for mandatory regulation of sugar in baby foods. PMID: 31131800 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Healthcare utilisation patterns for respiratory and gastrointestinal syndromes and meningitis in Msunduzi municipality, Pietermaritzburg, KwaZulu-Natal Province, South Africa, 2013.
CONCLUSIONS: Public health facility-based surveillance may be representative of disease patterns in this community, although surveillance at household level shows that high-income individuals may be excluded because they were more likely to use private healthcare, and the proportion of individuals who died at home would have been missed by facility-based surveillance. Data obtained in such surveys may be useful for public health planning. PMID: 31131801 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Prospective case-series analysis of haematological malignancies in goldmining areas in South Africa.
CONCLUSIONS: We identified potential environmental uranium exposure pathways (occupational, lifestyle related and domestic) among patients with HMs that could have resulted in increased uranium exposure. HIV is common among patients with HMs. Together with the results from a previous retrospective case series of HMs at CHBAH (2004 - 2013), our findings suggest that further research on environmental uranium exposure in mining areas and HM risk in residents is warranted. PMID: 31131802 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Screening and managing a low-risk pregnant population using continuous-wave Doppler ultrasound in a low-income population: A cohort analytical study.
CONCLUSIONS: The prevalence of AEDF in this low-risk population is ~10 times higher than that previously recorded. Use of the information prevented a number of perinatal deaths, most of which would have been macerated stillbirths. Screening a low-risk pregnant population using continuous-wave Doppler ultrasound may substantially reduce the prevalence of unexplained stillbirths in SA. PMID: 31131803 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Protecting participants in health research: The South African Material Transfer Agreement.
This article explores the need for a uniform MTA in SA and discusses some aspects of the recently gazetted national MTA, which provides a framework that can serve as a safeguard for cross-border transfer of HBMs in the absence of the National Health Act's chapter 8 regulations in this regard. PMID: 31131804 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 29, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Best practice recommendations for bladder management in spinal cord-afflicted patients in South Africa.
Authors: Theron F, Wilson V, Scriba E, Campbell R, Van Zyl M, Terry D, Visser A, Louw G, Seirlis A Abstract Recent research on the standard of care and related quality of life of the spinal cord-afflicted community in South Africa (SA) has revealed significant gaps in practice, and challenges regarding levels of care and access to services and supplies specifically related to the neurogenic bladder. PMID: 31084681 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 16, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Eligibility for co-trimoxazole prophylaxis among adult HIV-infected patients in South Africa.
Authors: Takuva S, Nabyoma JM, Dawood H, Black A, Maartens G, Parrish A, Leong TD Abstract PMID: 31084682 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 16, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Low-pressure fabric hyperbaric chambers.
Authors: Burman F Abstract Hyperbaric oxygen therapy is defined as an intervention in which an individual breathes near 100% oxygen while wholly enclosed inside a hyperbaric chamber at a pressure ≥1.4 atmosphere absolute (ATA). The Southern African Underwater and Hyperbaric Medical Association (SAUHMA)-approved indications commence at pressures ≥2 ATA. Low-pressure hyperbaric chambers, at pressures ≤1.4 ATA, are approved for acute mountain sickness only. Mild hyperbaric exposures with air deliver no more oxygen to the body than breathing oxygen by mask at sea level pressure. Exposure to treatment pressures...
Source: South African Medical Journal - May 16, 2019 Category: African Health Tags: S Afr Med J Source Type: research

The utility of hand-held mobile spirometer technology in a resource-constrained setting.
CONCLUSIONS: The mobile Air-Smart Spirometer compared well with conventional spirometry, making it an attractive and potentially affordable tool for screening purposes in a primary care setting. Moreover, it had a high sensitivity and NPV for obstructive ventilatory impairment. PMID: 31084684 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 16, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Spotted fever rickettsiosis in South Africa: Evaluation of laboratory diagnostic capacity and inter-laboratory comparison of serological testing.
CONCLUSIONS: Laboratory investigation for TBF is routinely and widely available in SA. Both serological and PCR-based methods were varied, and the lack of standardisation and interpretation of tests needs to be addressed to improve the overall quality of TBF diagnosis in SA. The utility of ILC to identify problem areas in serological testing for TBF is highlighted, and laboratories in SA are encouraged to use it to improve the quality of testing. PMID: 31084685 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 16, 2019 Category: African Health Tags: S Afr Med J Source Type: research

HIV self-screening distribution preferences and experiences among men who have sex with men in Mpumalanga Province: Informing policy for South Africa.
Authors: Radebe O, Lippman SA, Lane T, Gilmore H, Agnew E, Manyuchi A, McIntyre JA Abstract Current research suggests that HIV self-screening (HIVSS) is a feasible and acceptable approach to increase HIV testing among men who have sex with men (MSM). However, few data are available to shape policy around dissemination and implementation. Gaps in knowledge include preferences for distribution of HIVSS kits, potential social harms and benefits of their use, and how much test users would be willing to pay for the kits. The aim was to inform policy recommendations to optimise distribution of HIVSS kits to MSM in South ...
Source: South African Medical Journal - May 16, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Protection of Personal Information Act No. 4 of 2013: Implications for biobanks.
Authors: Staunton C, De Stadler E Abstract The Protection of Personal Information Act (POPIA) No. 4 of 2013 is the first comprehensive data-protection regulation to be passed in South Africa (SA). Its objectives include giving effect to the constitutional right to privacy by regulating the way in which personal information must be processed, balancing the right to privacy against other rights, and establishing an Information Regulator to ensure that the rights protected by POPIA are respected. POPIA will have an impact on health research, including biobanks. As sharing of samples and data is a central feature of bi...
Source: South African Medical Journal - May 16, 2019 Category: African Health Tags: S Afr Med J Source Type: research

The state of kidney transplantation in South Africa.
CONCLUSIONS: The overall transplant rate in SA is declining, especially in the public sector. Most kidney transplants in the country were performed in the public sector, and deceased-donor transplants predominated. Discrepancies exist in the allocation of kidneys. Recommendations are made on how the situation may be improved. PMID: 31084688 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 16, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Reducing maternal deaths by skills-and-drills training in managing obstetric emergencies: A before-and-after observational study.
CONCLUSIONS: Implementing a skills-and-drills EmOC training package was associated with a significant reduction in maternal deaths. PMID: 31084689 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 16, 2019 Category: African Health Tags: S Afr Med J Source Type: research

The incidence of melanoma in South Africa: An exploratory analysis of National Cancer Registry data from 2005 to 2013 with a specific focus on melanoma in black Africans.
CONCLUSIONS: This study provides up-to-date NCR incidence and demographic data on melanoma and highlights the neglected research gaps in relation to melanoma in black Africans to provide evidence needed to address health disparities in overlooked population groups. PMID: 31084690 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 16, 2019 Category: African Health Tags: S Afr Med J Source Type: research

How long does it take a registrar to complete the compulsory research project enabling specialist registration?
CONCLUSIONS: Large standard deviations and a wide range of finishing times detract from the positive findings that most dissertations were completed within the 4-year clinical training time period. Publication-ready dissertations significantly shortened MMed completion time. Unique study and work commitments and lack of research experience challenge speedy MMed completion. Existing research and supervisory supportive structures should be remodelled to better suit the research needs of the andragogic specialist registrar. PMID: 31084691 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 16, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Impact of Xpert MTB/RIF assay on multidrug-resistant tuberculosis treatment outcomes in a health district in South Africa.
CONCLUSIONS: Despite rapid treatment initiation, MDR-TB treatment outcomes were poorer in patients diagnosed with Xpert MTB/RIF assay than in the smear/culture cohort, and they were also poorer in men than in women. Additional studies are required to assess possible factors influencing DR-TB outcomes. PMID: 31084692 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 16, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Prevalence of comorbidities in women with and without breast cancer in Soweto, South Africa: Results from the SABC study.
CONCLUSIONS: A large proportion of women experience several comorbidities, highlighting the need to address the chronic non-communicable disease epidemic in SA and to co-ordinate multidisciplinary primary-, secondary- and tertiary-level care in the country's complex healthcare system for better outcome. PMID: 31084693 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 16, 2019 Category: African Health Tags: S Afr Med J Source Type: research

A review of the use of high-flow nasal cannula oxygen therapy in hospitalised children at a regional hospital in the Cape Town Metro, South Africa.
CONCLUSIONS: HFNC is a safe, effective, feasible option for non-invasive ventilation of children with respiratory illnesses in a resource-limited L2 setting. A greater proportion of children with lower respiratory tract infections in the HFNC-availability group than in the pre-HFNC group required support, but the intervention reduced the bed pressure on L3. Improved ways to identify HFNC failures would be beneficial. PMID: 31084694 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - May 16, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Validation of a brief mental health screening tool for common mental disorders in primary healthcare.
CONCLUSIONS: Using a higher specificity index, the positive predictive value and NPV show that at higher cut-point values the BMH not only helps identify individuals with alcohol misuse, depression and anxiety symptoms but also identifies a majority of those who do not have symptoms (true negatives), thus not overburdening nurses with false positives needing assessment. Research is needed to assess whether use of such a short and valid screening tool is generalisable to other clinic contexts as well as how mental health screening should best be introduced into routine clinic functioning and practice. PMID: 3108469...
Source: South African Medical Journal - May 16, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Manuscripts not suitable for general readership of the South African Medical Journal.
Authors: Joubert G, Mulder T, Steinberg WJ, Botes Response From The Editor J PMID: 30834853 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Latest results show urgent need to address child restraint use.
Authors: Clay C, Van As AB, Hunter K, Peden M PMID: 30834854 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Success brings new challenges in circumcision campaign.
Authors: Millard PS, Goldstuck N Abstract PMID: 30834855 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Reimagining liver transplantation in South Africa: A model for justice, equity and capacity building - the Wits Donald Gordon Medical Centre experience.
Authors: Tager S, Etheredge HR, Fabian J, Botha JF Abstract The challenge of providing effective and integrated liver transplant services across South Africa's two socioeconomically disparate healthcare sectors has been faced by Wits Donald Gordon Medical Centre (WDGMC) since 2004. WDGMC is a private academic hospital in Johannesburg and serves to supplement the specialist and subspecialist medical training provided by the University of the Witwatersrand. Over the past 14 years, our liver transplant programme has evolved from a sometimes fractured service into the largest-volume liver centre in sub-Saharan Africa. ...
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Life-threatening hyperkalaemia due to trimethoprim in a patient treated for Pneumocystis jirovecii pneumonia.
We report a case in which life-threatening hyperkalaemia developed after institution of high-dose co-trimoxazole for PJP. PMID: 30834857 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Atypical presentation of Crimean-Congo haemorrhagic fever: Lessons learned.
Authors: Krüger HJ, De Wet R, Blumberg LH, Weyer J, Lemke FG Abstract An atypical case of Crimean-Congo haemorrhagic fever is presented. The diagnosis of the case in the presence of several comorbidities was complicated and illustrates the importance of maintaining a high index of suspicion for viral haemorrhagic fever in cases presenting with multisystem disease and an epidemiological history that could present opportunities for exposure to a haemorrhagic fever virus. PMID: 30834858 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Midwife-led obstetric units working 'CLEVER': Improving perinatal outcome indicators in a South African health district.
CONCLUSIONS: CLEVER as a context-specific, multicomponent, clinically focused intervention package may have contributed to improved perinatal morbidity and mortality rates in MOUs. PMID: 30834859 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

The association between preterm labour, perinatal mortality and infant death (during the first year) in Bishop Lavis, Cape Town, South Africa.
CONCLUSIONS: Preterm birth and fetal growth restriction play significant roles in fetal, neonatal and infant losses. PMID: 30834860 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Factors related to hospital readmissions in people with spinal cord injury in South Africa.
CONCLUSIONS: Factors related to patient injury profile such as type, completeness and level of injury were associated with a significant risk of readmission. SHCs were the main cause of readmission, and there is a need for effective programmes for their prevention. PMID: 30834861 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Validation and effect on diabetes control of glycated haemoglobin (HbA1c) point-of-care testing.
CONCLUSIONS: The Quo-Test HbA1c POCT had good correlation with standard laboratory methods in respect of both glycaemic control and price. Patients who had POCT at baseline showed a significant improvement in glycaemic control at 3 months. HbA1c POCT in the setting of a multifaceted approach to diabetes care has been shown to have definite benefits. PMID: 30834862 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Mortality among older patients admitted to the medical wards of Groote Schuur Hospital, Cape Town, South Africa, 2010 - 2013.
CONCLUSIONS: Mortality among older medical inpatients was high. Modifiable predictors of mortality, especially related to laboratory derangements, should be identified and addressed promptly. PMID: 30834863 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Four-year review of admissions to a South African regional hospital general surgery department.
CONCLUSIONS: A precise understanding of the burden of disease profile is essential for national, provincial and district budgeting and resource allocation. Ongoing surveillance such as that performed in the study provides this critical information. PMID: 30834864 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

A retrospective review on benzodiazepine use: A case study from a chronic dispensary unit.
CONCLUSIONS: BZDs were most commonly prescribed to female patients and middle-aged adults. Clonazepam was the most frequently prescribed BZD, indicating a preference for long-acting BZDs. Epilepsy was the most common therapeutic indication and antiepileptics were the most common concomitant drug class prescribed, implying that BZDs have a primary role in the management of epileptic conditions in the public healthcare sector. Future studies should include the private sector, as regulations in the public sector greatly influence the patterns of BZD use. PMID: 30834865 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Medical students' perspectives on euthanasia and physician-assisted suicide and their views on legalising these practices in South Africa.
Authors: Bac M, Meyer E PMID: 30834866 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Reflections on undergraduate teaching.
Authors: Edge J Abstract PMID: 30834867 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

The apps are coming! But will they be legal in South Africa?
This article deals with ways in which technology could be used for certain tasks such as renewing prescriptions. Using technology in such a way would fall under the concept of telemedicine. Local guidelines are assessed to ascertain whether the use of apps by patients in South Africa for healthcare advice by doctors would be legal. PMID: 30834868 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Alternating hemiplegia of childhood: First South African case report and verapamil as a possible treatment option.
Authors: Van Hillegondsberg LS, Michaelis IA Abstract In this case report we describe a child with alternating hemiplegia of childhood, a rare neurodevelopmental disorder, and the effectiveness of an unconventional drug, verapamil, in treating this condition. PMID: 30834869 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Perioperative comparison of the agreement between a portable fingertip pulse oximeter v. a conventional bedside pulse oximeter in adult patients (COMFORT trial).
CONCLUSIONS: During normoxia, portable fingertip pulse oximeters are reliable indicators of SpO2and pulse rates in patients with various comorbidities in a pragmatic clinical context. However, they display worsening agreement with conventional pulse oximeters during hypoxaemia. Skin tones do not appear to affect measurements adversely. PMID: 30834870 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Delay to diagnosis and breast cancer stage in an urban South African breast clinic.
CONCLUSIONS: Most women delayed in seeking breast care. Facilitating direct access to specialist breast clinics may reduce delays in presentation and improve time to diagnosis and care. PMID: 30834871 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - March 7, 2019 Category: African Health Tags: S Afr Med J Source Type: research