Comorbidity in context: Part 1. Medical considerations around HIV and tuberculosis during the COVID-19 pandemic in South Africa.
Authors: Rossouw TM, Boswell MT, Nienaber AG, Moodley K Abstract Infectious diseases pandemics have devastating health, social and economic consequences, especially in developing countries such as South Africa. Scarce medical resources must often be rationed effectively to contain the disease outbreak. In the case of COVID-19, even the best-resourced countries will have inadequate intensive care facilities for the large number of patients needing admission and ventilation. The scarcity of medical resources creates the need for national governments to establish admission criteria that are evidence-based and fair. Qu...
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Comorbidity in context: Part 2. Ethicolegal considerations around HIV and tuberculosis during the COVID-19 pandemic in South Africa.
Authors: Rossouw TM, Nienaber AG, Boswell MT, Moodley K Abstract The COVID-19 pandemic has brought discussions around the appropriate and fair rationing of scare resources to the forefront. This is of special importance in a country such as South Africa (SA), where scarce resources interface with high levels of need. A large proportion of the SA population has risk factors associated with worse COVID-19 outcomes. Many people are also potentially medically and socially vulnerable secondary to the high levels of infection with HIV and tuberculosis (TB) in the country. This is the second of two articles. The first exa...
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

South Africa's coronavirus testing strategy is broken and not fit for purpose: It's time for a change.
Authors: Mendelson M, Madhi S PMID: 32880536 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

The utility of high-flow nasal cannula oxygen therapy in the management of respiratory failure secondary to COVID-19 pneumonia.
Authors: Lalla U, Allwood BW, Louw EH, Nortje A, Parker A, Taljaard JJ, Moodley D, Koegelenberg CFN PMID: 32880537 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Closed positive end-expiratory pressure system: Pre-oxygenation and ventilatory support in COVID-19.
Authors: D'Andrea I, Naidoo P, Schoeman E, Kotze C PMID: 32880538 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

COVID-19 restrictions and increased risk of overdose for street-based people with opioid dependence in South Africa.
Authors: Stowe MJ, Scheibe A, Shelly S, Marks M PMID: 32880539 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Prognosticating COVID-19: A need for Africa-specific laboratory predictors.
Authors: Omuse G, Maranga J, Abdillah A, Maina D PMID: 32880540 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

COVID-19 infection in Italy: An occupational injury.
Authors: Chirico F, Magnavita N PMID: 32880541 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Assessment of sputum cultures for the diagnosis of lower-respiratory tract infections in the outpatient setting.
Authors: Chanda R, Opperman CJ PMID: 32880542 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

How South Africa's Ministerial Advisory Committee on COVID-19 can be optimised.
Authors: Singh JA PMID: 32880543 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Building trust during COVID 19: Value-driven and ethical priority-setting.
Authors: Mosam A, Goldstein S, Erzse A, Tugendhaft A, Hofman K PMID: 32880544 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

COVID-19: Science and global health governance under attack.
Authors: Singh JA Abstract Less than 3 months after the World Health Organization (WHO) declared COVID-19 a Public Health Emergency of International Concern, and within a month of the WHO declaring COVID19 a global pandemic, COVID-19 infections and fatalities have grown exponentially, globally. Now, more than ever, the world needs responsible political leadership, evidence-based decision-making, and co-ordinated global health action. PMID: 32880545 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Remdesivir and COVID-19: What are the implications for Africa?
Authors: Green RJ, Mustafa F, Sewlall N, Richards GA PMID: 32880546 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

The implications of COVID-19 for the children of Africa.
Authors: Mustafa F, Green R PMID: 32880547 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Pandemics, professionalism and the duty of care: Concerns from the coalface.
Authors: Dhai A, Veller M, Ballot D, Mokhachane M Abstract It is likely that the SARS-CoV-2 pandemic will affect a large part of the world's population and will last for several years. Many critical ethical issues have arisen in the healthcare context. While response from healthcare professionals to participating in the care of patients in the era of COVID-19 has generally been positive, there have also been disturbing experiences on the ground. The practice of medicine is a social contract with humanity. Challenges have arisen because the patient is both a victim and a vector of the coronavirus. All humans should ...
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

COVID-19: Mandatory institutional isolation v. voluntary home self-isolation.
Authors: Singh JA Abstract Since community transmission of COVID-19 became established in South Africa, individuals who test positive for COVID-19 and who do not require hospitalisation have been permitted to self-isolate in their homes to reduce the burden on the health system. The Premier of KwaZulu-Natal Province has since announced that self-isolation will no longer be permitted in the province. Instead, mandatory isolation in state-designated isolation sites would apply. This policy change marks a dangerous departure from the country's prevailing position on home-based self-isolation and should not be replicat...
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Isolation and quarantine in South Africa during COVID-19: Draconian measures or proportional response?
Authors: Moodley K, Obasa AE, London L Abstract In the midst of an unprecedented public health crisis, extraordinary containment measures must be implemented. These include both isolation and quarantine, either on a voluntary basis or enforced. In the transition from voluntary to mandatory isolation, conflicts arise at the intersection of ethics, human rights and the law. The Siracusa Principles adopted by the United Nations Economic and Social Council in 1985 and enshrined in international human rights legislation and guidelines specify conditions under which civil liberties may be infringed. In order for isolatio...
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Criminalisation of transmission of SARS-CoV-2: A potential challenge to controlling the outbreak in South Africa.
This article explores whether SA's existing HIV criminalisation laws can be applied to the transmission of SARS-CoV-2, and the potential effect such measures could have on efforts to control the COVID-19 epidemic. PMID: 32880551 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

COVID-19 and patient-doctor confidentiality.
Authors: McQuoid-Mason DJ Abstract Given the increasing numbers of ethical and legal issues arising from the COVID-19 epidemic, particularly in respect of patient-doctor confidentiality, doctors must explain to patients how the measures taken to combat the spread of the virus impact on their confidentiality. Patients must be reassured that doctors are ethically bound to continue to respect such confidentiality, but it should be made clear to them that doctors must also comply with the demands of the law. While the Constitution, statutory law and the common law all recognise a person's right to privacy, during extra...
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Leadership and early strategic response to the SARS-CoV-2 pandemic at a COVID-19 designated hospital in South Africa.
We describe our early response as a designated COVID-19 provincial hospital in Cape Town, South Africa (SA).While the first cases reported were related to international travel, at the time of writing there was evidence of early community spread. The SAgovernment announced a countrywide lockdown from midnight 26 March 2020 to midnight 30 April 2020 to stem the pandemic and save lives. However, many questions remain on how the COVID-19 threat will unfold in SA, given the significant informal sector overcrowding and poverty in our communities. There is no doubt that leadership and teamwork at all levels is critical ...
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Personal protective equipment (PPE) in a pandemic: Approaches to PPE preservation for South African healthcare facilities.
This article discusses the available PPE preservation strategies and addresses the issue of decontamination and re-use of N95 respirators as a last-resort strategy for critical shortages during the pandemic. PMID: 32880554 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

COVID-19 and quarantine orders: A practical approach.
This article explains the legal and ethical considerations of this balancing exercise and provides practical guidance for obtaining quarantine orders. PMID: 32880555 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

HIV and SARS-CoV-2 co-infection: The diagnostic challenges of dual pandemics.
We describe the diagnostic and therapeutic challenges presented by this case. PMID: 32880556 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Quarantine alone or in combination with other public health measures to control COVID-19: A rapid Cochrane review.
Authors: Schmidt B, Davids EL, Malinga T Abstract In March 2020, the South African government implemented various non-pharmacological prevention and control measures (e.g. isolation, social distancing and quarantine) in response to the COVID-19 pandemic. We summarise evidence from a rapid Cochrane review on the effect of quarantine alone v. quarantine plus combination measures to prevent transmission of and mortality caused by COVID-19. The findings show that when started earlier, quarantine combined with other prevention and control measures can be more effective than quarantine alone, and cost less. PMID: 328...
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Transmission of respiratory viruses when using public ground transport: A rapid review to inform public health recommendations during the COVID-19 pandemic.
Authors: Zhen J, Chan C, Schoonees A, Apatu E, Thabane L, Young T Abstract In response to the COVID-19 pandemic, numerous countries worldwide declared national states of emergency and implemented interventions to minimise the risk of transmission among the public. Evidence was needed to inform strategies for limiting COVID-19 transmission on public transport. On 20 March 2020, we searched MEDLINE, CENTRAL, Web of Science and the World Health Organization's database of 'Global research on coronavirus disease (COVID-19)' to conduct a rapid review on interventions that reduce viral transmission on public ground transp...
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Analysis of the airway registry from an academic emergency department in South Africa.
CONCLUSIONS: This analysis of the first airway registry from an SA ED highlights that airway management in an LMIC can be performed on par with accepted international standards. It serves as a good baseline for further research into airway management in other LMICs and provides useful feedback for quality improvement purposes. PMID: 32880559 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Predictors of 1-year survival in South African transcatheter aortic valve implant candidates.
CONCLUSIONS: Apart from existing predictors, we identified three novel risk predictors (independent living, ability to drive a car, and independent food acquisition/cooking) for 1-year survival in TAVI candidates. These novel parameters performed well in this early evaluation, with an AUC for predicting 1-year survival higher than the AUCs for many of the internationally derived parameters. The parameters are inexpensive and easy to obtain at the initial patient visit. If validated prospectively in external cohorts, they may be applicable to other resource-constrained environments. PMID: 32880560 [PubMed - in process] ...
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

An analysis of neonates with surgical diagnoses admitted to the neonatal intensive care unit at Charlotte Maxeke Johannesburg Academic Hospital, South Africa.
CONCLUSIONS: Neonates with major surgical conditions accounted for one-third of NICU admissions in the present study. The study highlights the considerable burden placed on paediatric surgical services at a large referral hospital in SA. Paediatric surgical services, with early referral and improvement of neonatal transport systems, must be a priority in planned healthcare interventions to reduce neonatal mortality in LMICs. PMID: 32880561 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

A retrospective cohort study comparing pregnancy outcomes and neonatal characteristics between HIV-infected and HIV-non-infected mothers.
CONCLUSIONS: HIV infection that has been treated does not appear to be an independent risk factor for fetal growth restriction or preterm delivery in an SA population. PMID: 32880562 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Documented higher burden of advanced and very advanced HIV disease among patients, especially men, accessing healthcare in a rapidly growing economic and industrial hub in South Africa: A call to action.
CONCLUSIONS: Lower median CD4+ counts and a dramatic increase in volumes of CD4+ tests performed from 2007 onwards revealed a high burden of advanced and very advanced HIV disease in patients accessing care in Lephalale. Viewed together with Statistics South Africa census documentation of a disproportionately high number of males compared with females living in the area, these figures suggest that improved systems are urgently needed to encourage and accommodate access to HIV care for male (migrant worker) patients living and working in emerging industrial centres. PMID: 32880563 [PubMed - in process] (Source: South Af...
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Ever and repeat HIV testing rates among male and female clients: Findings from a reproductive health services integration project in South Africa.
CONCLUSIONS: HIV testing and repeat testing increased over time, especially in males and in HTS. Promotion and integration of SRH services are critical to facilitate improved health-seeking behaviour and HIV testing of both male and female clients. They are also important for continued access to HTS at multiple service delivery points. PMID: 32880564 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Prevalence and outcome of delirium among acute general medical inpatients in Cape Town, South Africa.
CONCLUSIONS: In this cohort of medical inpatients (relatively young and with a high HIV prevalence) 1 of 8 (12.3%) patients was delirious. Delirium was associated with adverse outcomes. Delirium risk factors in this young cohort were similar to those in geriatric cohorts in developed countries, and neither HIV nor opportunistic infections increased risk. PMID: 32880565 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Lessons learnt during the national introduction of human papillomavirus (HPV) vaccination programmes in 6 African countries: Stakeholders' perspectives.
CONCLUSIONS: Most African countries do not have established platforms to deliver vaccines to pre-adolescent and adolescent populations. The successful introduction of the HPV vaccine through school-based vaccination strategies in African countries may have created a platform to deliver other adolescent vaccines. The similarity of the study findings across the 6 participating countries further strengthens the need to document and disseminate the challenges and lessons learnt during HPV vaccine introduction in Africa. Documentation and dissemination of the challenges and lessons learnt are useful to other countries in Africa...
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Viewership footprint for a low-resource, student-centred collaborative video platform to teach orthopaedics in southern Africa.
CONCLUSIONS: Our study provides proof of concept for a new educational material creation and dissemination strategy. A low-cost local collaborative orthopaedic video project by medical students for medical students can lead to high view counts and watch time on YouTube. It is accessible to audiences in low-, middle- and high-income countries. The students' educational videos also reached a global audience consistently over a 3-year period. PMID: 32880567 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Thirty-day readmission rate: A predictor of initial surgical severity or quality of surgical care? A regional hospital analysis.
CONCLUSIONS: The Department of General Surgery, Worcester Hospital, had a readmission rate comparable with that in HICs. Readmission rate is an indicator of advanced surgical pathology requiring an operative intervention of greater magnitude, often presenting as an emergency. Our results can be used to improve postoperative surveillance and ultimately improve outcomes in high-risk surgical populations. This study provides a benchmark for other regional hospitals in SA and has implications for quality-improvement programmes. PMID: 32880568 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Clinical characteristics and treatment outcomes of women with heroin dependence in Johannesburg, South Africa.
CONCLUSIONS: Women with heroin dependence in Johannesburg have high rates of HIV infection and comorbid mental illness and low rates of abstinence after inpatient detoxification and psychosocial therapy. Women fared worse than men in many domains of treatment outcome. This study builds evidence for the need for gender-sensitive substance rehabilitation facilities in SA. PMID: 32880569 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Prevalence of hookah pipe smoking in high-school learners in Johannesburg, South Africa.
CONCLUSIONS: HP smoking increased significantly between grades 8 and 12. Increasing knowledge and awareness of the risks involved in HP smoking in children at an early age is recommended. One of the factors influencing uptake of HP smoking in young students was having a family member smoking it; adult anti-smoking and anti-HP campaigns are therefore also important. PMID: 32880570 [PubMed - in process] (Source: South African Medical Journal)
Source: South African Medical Journal - September 6, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Ending HIV/AIDS: Not as close as many would have us believe.
Authors: Rotheram-Borus MJ, Gordon S, Christodoulou J, Tomlinson M PMID: 32657673 [PubMed - as supplied by publisher] (Source: South African Medical Journal)
Source: South African Medical Journal - July 14, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Renal denervation in South Africa.
Authors: Heradien MJ, Van der Bijl P, Brink PA PMID: 32657674 [PubMed - as supplied by publisher] (Source: South African Medical Journal)
Source: South African Medical Journal - July 14, 2020 Category: African Health Tags: S Afr Med J Source Type: research

The Competition Commission Health Market Inquiry Report: An overview and key imperatives.
The objective of this article is to contribute to this discussion by providing an overview of the key findings and recommendations of the HMI and highlighting the resultant key imperatives at this critical juncture of policy development. PMID: 32657675 [PubMed - as supplied by publisher] (Source: South African Medical Journal)
Source: South African Medical Journal - July 14, 2020 Category: African Health Tags: S Afr Med J Source Type: research

An analysis of recent stroke cases in South Africa: Trend, seasonality and predictors.
CONCLUSIONS: The increasing trend of stroke in SA should be arrested urgently, taking into account both the associated risk factors and seasonality. PMID: 32657676 [PubMed - as supplied by publisher] (Source: South African Medical Journal)
Source: South African Medical Journal - July 14, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Parents refusing blood transfusions for their children solely on religious grounds: Who must apply for the court order?
Authors: McQuoid-Mason DJ Abstract The South African Constitution provides that children have the right to healthcare, as well as all other rights. Furthermore, in all matters affecting them, their best interests must be 'of paramount importance'. It seems common practice that, when parents refuse blood transfusions for their children solely on religious grounds, doctors and health authorities apply for a court order to overturn such refusals. However, since the implementation of the Children's Act of 2005, it may be that the onus is no longer on doctors and authorities to apply to court to reverse the decision of ...
Source: South African Medical Journal - July 14, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Understanding the basics of cannabidiol from cannabis to apply to therapeutics in epilepsy.
Authors: Hay L Abstract The compounds present in cannabis have been in use for both recreational and medicinal purposes for many centuries. Changes in the legislation in South Africa have led to an increase in the number of people interested in using these compounds for self-medication. Many of them may approach their general practitioner as the first source of information about possible therapeutic effects. It is important that medical professionals are able to give patients the correct information. Cannabidiol (CBD) is one of the main compounds in cannabis plants, and there is evidence that it can successfully tr...
Source: South African Medical Journal - July 14, 2020 Category: African Health Tags: S Afr Med J Source Type: research

A decade of hepatitis C at the University of Cape Town/Groote Schuur Hospital Liver Clinic, South Africa, in the pre-direct-acting antivirals era.
CONCLUSIONS: HCV patients in the Peg-IFN/RBV management era typified the epidemiology of HCV. GT distribution was pangenotypic, and treatment outcomes were encouraging despite treatment challenges. Patient selection, IL28B and sensible support of cytopenias probably accounted for these favourable outcomes. However, numbers treated were limited, and the DAA era of therapy allows for rapid expansion of therapy with now growing numbers of patients and a changing local epidemiology. PMID: 32657679 [PubMed - as supplied by publisher] (Source: South African Medical Journal)
Source: South African Medical Journal - July 14, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Direct-acting antiviral therapy for hepatitis C: The initial experience of the University of Cape Town/Groote Schuur Hospital Liver Clinic, South Africa.
CONCLUSIONS: DAA therapy for HCV in a pan-genotypic group of patients, many with advanced liver disease, was highly effective. Our outcomes correspond with existing trial and real-world data for similar treatment. DAA therapy and access need rapid upscaling in SA, especially targeting key populations at point of care. PMID: 32657680 [PubMed - as supplied by publisher] (Source: South African Medical Journal)
Source: South African Medical Journal - July 14, 2020 Category: African Health Tags: S Afr Med J Source Type: research

HIV and breast cancer - a mammographic analysis: An observational study to identify the mammographic pattern of breast cancer in HIV-positive patients.
CONCLUSIONS: We demonstrated a statistically significant relationship between HIV status, the presence of multifocal breast cancer, and mammographically detected grouped and fine pleomorphic microcalcifications. A statistically significant relationship between HGDCIS and HIV status, and the presence of grouped and fine pleomorphic microcalcifications in HIV-positive patients with biopsies confirming HGDCIS, was demonstrated. Our study also showed that there is a relationship between age of presentation and HIV status. PMID: 32657681 [PubMed - as supplied by publisher] (Source: South African Medical Journal)
Source: South African Medical Journal - July 14, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Nosocomial infections: A further assault on patients in a high-volume urban trauma centre in South Africa.
CONCLUSIONS: A combination of measures is required to prevent trauma-related infections. By determining the incidence of nosocomial infections in our trauma patients, uniform policies to reduce infection rates further could be determined. Our low incidence of infection may be explained by established preventive care bundles already in place. PMID: 32657682 [PubMed - as supplied by publisher] (Source: South African Medical Journal)
Source: South African Medical Journal - July 14, 2020 Category: African Health Tags: S Afr Med J Source Type: research

Point-of-care CD4+ technology implementation in Free State, South Africa, was associated with improved patient health outcomes.
CONCLUSIONS: Introduction of the Alere Pima POC CD4+ technology in the Free State, operated by nurses and lay counsellors, was associated with positive patient outcomes across all parameters analysed. While this study highlighted an effective conventional laboratory network, a full costing and affordability analysis coupled with patient impact and access data from this study will provide further insight into the potential deployment strategies of POC CD4+ technologies in SA. PMID: 32657683 [PubMed - as supplied by publisher] (Source: South African Medical Journal)
Source: South African Medical Journal - July 14, 2020 Category: African Health Tags: S Afr Med J Source Type: research

A 10-year analysis of organ donor referrals to a South African tertiary public sector hospital.
CONCLUSIONS: Donor referral patterns have changed over time, with a notable increase in medical and extended criteria donors. Despite the increase in possible and eligible donors, the consent rate has declined. Further qualitative and quantitative research studies are required to understand and address this trend. PMID: 32657684 [PubMed - as supplied by publisher] (Source: South African Medical Journal)
Source: South African Medical Journal - July 14, 2020 Category: African Health Tags: S Afr Med J Source Type: research

The impact of diagnostic methods on the diagnosis of Clostridiodes difficile infection.
CONCLUSIONS: The choice of laboratory testing method has a major impact on the diagnosis of CDI, and therefore on reported rates of CDI. Standardisation of laboratory testing and incidence rate reporting is required in order to obtain robust and reliable data. PMID: 32657685 [PubMed - as supplied by publisher] (Source: South African Medical Journal)
Source: South African Medical Journal - July 14, 2020 Category: African Health Tags: S Afr Med J Source Type: research