Congestion patterns in severe tricuspid regurgitation and transcatheter treatment: Insights from a multicentre registry
ConclusionIn this large cohort of invasively characterized patients undergoing TTVI, congestion patterns involving right-sided congestion were associated with low procedural success and higher mortality rates after TTVI. Whether pre-interventional reduction of right-sided congestion can improve outcomes after TTVI should be established in dedicated studies. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 4, 2024 Category: Cardiology Authors: Karl ‐Philipp Rommel, Guillaume Bonnet, Vera Fortmeier, Lukas Stolz, Anne R. Schöber, Jennifer von Stein, Mohammad Kassar, Muhammed Gerçek, Sebastian Rosch, Thomas J. Stocker, Maria I. Körber, Karl‐Patrik Kresoja, Tanja K. Rudolph, Rom Tags: Research Article Source Type: research

ALCAPA in Children with Complex Congenital Heart Disease: A Multicenter Study
AbstractWe sought to report characteristics and outcomes of children with complex anomalous left coronary artery from the pulmonary artery (ALCAPA) and to  compare the outcomes to children with isolated ALCAPA. We performed a retrospective data analysis of children with ALCAPA who underwent cardiac surgery between 1/2009 and 3/2018 at 21 centers. Characteristics and outcomes of patients with complex ALCAPA are provided using descriptive statistics. O utcomes were compared between complex ALCAPA and isolated ALCAPA using Fisher’s exact test. We reviewed 258 patients who underwent surgical repair of ALCAPA at 21 centers. ...
Source: Pediatric Cardiology - April 3, 2024 Category: Cardiology Source Type: research

Performance of DETECT Pulmonary Arterial Hypertension Algorithm According to the Hemodynamic Definition of Pulmonary Arterial Hypertension in the 2022 European Society of Cardiology and the European Respiratory Society Guidelines
ConclusionThe performance of the DETECT algorithm to screen for PAH in patients with SSc is maintained when PAH is defined according to the 2022 ESC/ERS hemodynamic definition, indicating that DETECT remains applicable to screen for PAH in patients with SSc. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - April 2, 2024 Category: Rheumatology Authors: Oliver Distler, Diana Bonderman, J. Gerry Coghlan, Christopher P. Denton, Ekkehard Gr ünig, Dinesh Khanna, Vallerie V. McLaughlin, Ulf Müller‐Ladner, Janet E. Pope, Madelon C. Vonk, Lilla Di Scala, Jean‐Christophe Lemarie, Loïc Perchene Tags: Brief Report Source Type: research

Arginine-NO metabolites are associated with morbidity in single ventricle infants undergoing stage 2 palliation
CONCLUSION: Arginine metabolism is impaired in interstage SVHD infants and is further deranged following Stage 2 palliation. Patients with greater metabolite alterations experience greater post-op morbidity. Decreased arginine metabolism may be an important driver of pathology in SVHD.IMPACT: Interstage infants with SVHD have significantly altered arginine-nitric oxide metabolism compared to healthy children with deficiency of multiple pathway intermediates persisting through 48 h post-Stage 2 palliation. After controlling for clinical covariates and classic catheterization-derived predictors of Stage 2 readiness, both low...
Source: Pediatric Research - April 2, 2024 Category: Pediatrics Authors: Benjamin S Frank Sierra Niemiec Ludmila Khailova Christopher A Mancuso Tanner Lehmann Max B Mitchell Gareth J Morgan Mark Twite Michael V DiMaria Jelena Klawitter Jesse A Davidson Source Type: research

Impact of pulmonary hypertension on outcomes after TEER in patients suffering from mitral regurgitation
CONCLUSION: PAWP at baseline was significantly and independently associated with HFH and might serve as a valuable parameter for identifying patients at high risk for HFH after M-TEER. ACM and procedural success were not affected by pulmonary arterial pressure before M-TEER. We suggest that the post-capillary component of PH serves as the driving force behind the risk of HFH.PMID:38565712 | DOI:10.1007/s00392-024-02442-1 (Source: Clin Med Res)
Source: Clin Med Res - April 2, 2024 Category: Research Authors: Philippa Jaeger Ioannis Toskas Jessica-Kristin Henes Serhii Shcherbyna Frederic Schwarz Miriam Euper Peter Seizer Harald Langer Andreas E May Tobias Geisler Meinrad Gawaz J ürgen Schreieck Dominik Rath Source Type: research

Impact of pulmonary hypertension on outcomes after TEER in patients suffering from mitral regurgitation
CONCLUSION: PAWP at baseline was significantly and independently associated with HFH and might serve as a valuable parameter for identifying patients at high risk for HFH after M-TEER. ACM and procedural success were not affected by pulmonary arterial pressure before M-TEER. We suggest that the post-capillary component of PH serves as the driving force behind the risk of HFH.PMID:38565712 | DOI:10.1007/s00392-024-02442-1 (Source: Clin Med Res)
Source: Clin Med Res - April 2, 2024 Category: Research Authors: Philippa Jaeger Ioannis Toskas Jessica-Kristin Henes Serhii Shcherbyna Frederic Schwarz Miriam Euper Peter Seizer Harald Langer Andreas E May Tobias Geisler Meinrad Gawaz J ürgen Schreieck Dominik Rath Source Type: research

Performance of DETECT Pulmonary Arterial Hypertension Algorithm According to the Hemodynamic Definition of Pulmonary Arterial Hypertension in the 2022 European Society of Cardiology and the European Respiratory Society Guidelines
ConclusionThe performance of the DETECT algorithm to screen for PAH in patients with SSc is maintained when PAH is defined according to the 2022 ESC/ERS hemodynamic definition, indicating that DETECT remains applicable to screen for PAH in patients with SSc. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - April 2, 2024 Category: Rheumatology Authors: Oliver Distler, Diana Bonderman, J. Gerry Coghlan, Christopher P. Denton, Ekkehard Gr ünig, Dinesh Khanna, Vallerie V. McLaughlin, Ulf Müller‐Ladner, Janet E. Pope, Madelon C. Vonk, Lilla Di Scala, Jean‐Christophe Lemarie, Loïc Perchene Tags: Brief Report Source Type: research

Impact of pulmonary hypertension on outcomes after TEER in patients suffering from mitral regurgitation
ConclusionPAWP at baseline was significantly and independently associated with HFH and might serve as a valuable parameter for identifying patients at high risk for HFH after M-TEER. ACM and procedural success were not affected by pulmonary arterial pressure before M-TEER. We suggest that the post-capillary component of PH serves as the driving force behind the risk of HFH. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - April 2, 2024 Category: Cardiology Source Type: research

Using Intracardiac Echocardiography Along with Transaortic Gradient to Clinch the Diagnosis in a Complicated LVAD Patient
We present a case series of 8 LVAD patients who underwent TAVR placement at our center. Here we highlight a complicated patient diagnosed with AI using a RAMP study combined with intracardiac echocardiogram (ICE), right and left heart catheterization calculating the Transaortic Gradient (TAG) (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Behfar Source Type: research

Coexistence of pulmonary arterial hypertension and straight back syndrome in a patient with a novel BMPR2 variant affecting cytoplasmic tail domain
ConclusionsThis is the first report of different straight back characteristics in heritable pulmonary arterial hypertension with a novel germlineBMPR2 variant. This finding may provide a new perspective on the variable penetrance of the pulmonary arterial hypertension phenotype. (Source: European Journal of Medical Research)
Source: European Journal of Medical Research - April 1, 2024 Category: Research Source Type: research

Longitudinal Cost Analysis for Pediatric Cardiac Transplant Recipients
Purpose: Healthcare costs have increased steadily over the past 4 decades. One of the key drivers of cost for pediatric heart transplant (PHTx) recipients is the frequency of cardiac catheterization with endomyocardial biopsy (EMB), the current “gold standard” for evaluating myocardial health. Novel cardiac magnetic resonance imaging (CMR) data may allow for non-invasive screening of PHTx. We sought to conduct a longitudinal cost analysis to compare the cost of CMR versus EMB screening over the lifetime of a PHTx. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: K. Yan, S. Kindel, A. Duffin, G. Stendahl, K. Crum, C. Lockard, B. Damon, J. Soslow, Source Type: research