Real-world diagnostic landscape and incidence of pulmonary hypertension in adult congenital heart disease patients using administrative claims data in Japan
CONCLUSION: We have clarified the frequency of diagnostic tests related to PH/ES and the incidence of PH/ES in patients with ACHD in clinical practice in Japan, including non-specialist institutions for PH.PMID:38420663 | DOI:10.1080/03007995.2024.2323632 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 29, 2024 Category: Research Authors: Tomoko Ishizu Yasuhiro Hayashi Natsuko Tokushige Junichi Omura Source Type: research

Real-world diagnostic landscape and incidence of pulmonary hypertension in adult congenital heart disease patients using administrative claims data in Japan
Conclusion: We have clarified the frequency of diagnostic tests related to PH/ES and the incidence of PH/ES in patients with ACHD in clinical practice in Japan, including non-specialist institutions for PH.PMID:38420663 | DOI:10.1080/03007995.2024.2323632 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 29, 2024 Category: Research Authors: Tomoko Ishizu Yasuhiro Hayashi Natsuko Tokushige Junichi Omura Source Type: research

Real-world diagnostic landscape and incidence of pulmonary hypertension in adult congenital heart disease patients using administrative claims data in Japan
CONCLUSION: We have clarified the frequency of diagnostic tests related to PH/ES and the incidence of PH/ES in patients with ACHD in clinical practice in Japan, including non-specialist institutions for PH.PMID:38420663 | DOI:10.1080/03007995.2024.2323632 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 29, 2024 Category: Research Authors: Tomoko Ishizu Yasuhiro Hayashi Natsuko Tokushige Junichi Omura Source Type: research

Techniques for Identifying a Patent Foramen Ovale
Noninvasive and invasive imaging modalities play important roles for the detection of patent foramen ovale (PFO). Transthoracic echocardiography or transcranial Doppler bubble study can be used for initial noninvasive PFO screening. For diagnostic confirmation, transesophageal echocardiography bubble study can be utilized, a semiinvasive confirmatory test that can directly visualize a PFO. In selective cases when the diagnosis is in doubt, PFO can be accurately diagnosed invasively with right heart catheterization. Understanding the advantages and limitations of each diagnostic option will help clinicians choose the approp...
Source: Cardiology Clinics - February 29, 2024 Category: Cardiology Authors: Sanaullah Mojaddedi, Muhammad O. Zaman, Islam Y. Elgendy, Mohammad K. Mojadidi Source Type: research

Impact of Pressure Recovery Adjustment on Aortic Valve Area Classification of Disease Severity in Transcatheter Aortic Valve Replacement Patients
The presence of pressure recovery (PR) in aortic stenosis (AS) was first appreciated with the use of Doppler in the early 1980 ’s. 1 PR has been described as the reconversion of kinetic energy to potential energy as the blood passes through the stenotic aortic valve (AV) into the proximal ascending aorta. PR partially explains the discrepancy between pressure gradients measured by direct heart catheterization and Doppler echocardiography. 2,3 The application of the energy loss coefficient (ELCO) overcomes this discrepancy by considering the energy conversion beyond the stenotic AV. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - February 29, 2024 Category: Anesthesiology Authors: Luis F. Gonzalez-Ciccarelli, Renan A. Ferrufino, Abdulaziz Alfadhel, Ethan Brovman, Jamel Ortoleva, Benjamin S. Wessler, Michael Fettiplace, Frederick Cobey Tags: Original Article Source Type: research

Cardiac Catheterization in Adults with Ebstein Anomaly: Pathophysiologic Insights Regarding Surgical Repair and Prognosis
AbstractThe underlying invasive hemodynamics and physiology in Ebstein anomaly (EA) are poorly understood. Moreover, the hemodynamic impact of tricuspid valve intervention in EA has not been well studied. Retrospective cohort of 52 adults with repaired and 36 with unrepaired EA undergoing right heart catheterization at Mayo Clinic, MN between 1993 and 2021. “Repaired” EA was defined as prior tricuspid valve repair and/or replacement (83% post-tricuspid valve replacement). Repaired patients were younger than those with unrepaired EA (41.3 ± 16.0 versus 50.6 ± 15.6 years,p = 0.008) and had a lower prevalen...
Source: Pediatric Cardiology - February 28, 2024 Category: Cardiology Source Type: research

A better method to evaluate the reliability of echocardiography for assessment of pulmonary hypertension: comparison of tricuspid regurgitant spectrum quality grading and tricuspid valve regurgitation degree
CONCLUSIONS: The US-PASP with TR-SQG III or IV is trustworthy, and its accuracy and consistency are better than those predicted by the traditional severity of TR. The establishment of the ultrasound evaluation system of TR-SQG helps clinicians to judge whether the US-PASP is accurate, credible, and reliable.PMID:38410615 | PMC:PMC10894378 | DOI:10.21037/jtd-23-1084 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - February 27, 2024 Category: Respiratory Medicine Authors: Weimin Deng Wenliang Guo Aiping Yang Dongyuan Lin Yantong Cai Yuanmei Zhang Ting Sun Shuting Yang Cheng Hong Xiaoping Huang Jiye Du Shangwei Ding Source Type: research

Right ventricular performance during acute hypoxic exercise
In conclusion, resting and exertional RV functions are preserved in response to acute exposure to hypoxia at an F i O 2 ${F_{{\mathrm{i}}{{\mathrm{O}}_{\mathrm{2}}}}}$ = 0.12 and the associated increase in PA pressures. KEY POINTS: The healthy right ventricle augments contractility, lusitropy and energetics during periods of increased metabolic demand (e.g. exercise) in acute hypoxic conditions. During submaximal exercise, ventricular-arterial coupling decreases but remains within normal limits, ensuring that cardiac output and systemic perfusion are maintained. These data describe right ventricular physiological respo...
Source: The Journal of Physiology - February 27, 2024 Category: Physiology Authors: Lindsay M Forbes Todd M Bull Tim Lahm Tyler Sisson Katie O'Gean Justin S Lawley Kendall Hunter Benjamin D Levine Andrew Lovering Robert C Roach Andrew W Subudhi William K Cornwell Source Type: research

Right ventricular performance during acute hypoxic exercise
In conclusion, resting and exertional RV functions are preserved in response to acute exposure to hypoxia at an F i O 2 ${F_{{\mathrm{i}}{{\mathrm{O}}_{\mathrm{2}}}}}$ = 0.12 and the associated increase in PA pressures. KEY POINTS: The healthy right ventricle augments contractility, lusitropy and energetics during periods of increased metabolic demand (e.g. exercise) in acute hypoxic conditions. During submaximal exercise, ventricular-arterial coupling decreases but remains within normal limits, ensuring that cardiac output and systemic perfusion are maintained. These data describe right ventricular physiological respo...
Source: The Journal of Physiology - February 27, 2024 Category: Physiology Authors: Lindsay M Forbes Todd M Bull Tim Lahm Tyler Sisson Katie O'Gean Justin S Lawley Kendall Hunter Benjamin D Levine Andrew Lovering Robert C Roach Andrew W Subudhi William K Cornwell Source Type: research

A better method to evaluate the reliability of echocardiography for assessment of pulmonary hypertension: comparison of tricuspid regurgitant spectrum quality grading and tricuspid valve regurgitation degree
CONCLUSIONS: The US-PASP with TR-SQG III or IV is trustworthy, and its accuracy and consistency are better than those predicted by the traditional severity of TR. The establishment of the ultrasound evaluation system of TR-SQG helps clinicians to judge whether the US-PASP is accurate, credible, and reliable.PMID:38410615 | PMC:PMC10894378 | DOI:10.21037/jtd-23-1084 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - February 27, 2024 Category: Respiratory Medicine Authors: Weimin Deng Wenliang Guo Aiping Yang Dongyuan Lin Yantong Cai Yuanmei Zhang Ting Sun Shuting Yang Cheng Hong Xiaoping Huang Jiye Du Shangwei Ding Source Type: research