Ultrasound Assessment of Pulmonary Artery Stiffening Associated with Pulmonary Hypertension in Left Heart Disease
Purpose: Diagnosis of pulmonary hypertension (PH) in patients with left heart disease (LHD) commonly occurs late in the disease process, as right heart catheterization is not routinely performed in LHD patients due to its inherent adverse effects. As such, there is an unmet clinical need for non-invasive techniques to detect and monitor PH in LHD. Having identified PA stiffening as both a pathomechanism and therapeutic target in PH-LHD in our previous work (Kucherenko et al, Nat. Comm. 2023), the current study aimed to develop a non-invasive index for the diagnosis of PA stiffening using a translational ultrasound-based ap...
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , M. Kukucka, P. Sang, N. Hegemann, F. Hennig, R. Yeter, T. Gransar, A. Mladenow, A. Emmerich, A. Orsenigo, J. Grune, V. Falk, W.M. Kuebler, C. Knosalla Source Type: research
Evaluating biomarkers for contrast-induced nephropathy following coronary interventions: an umbrella review on meta-analyses
ConclusionNGAL demonstrated superior diagnostic performance, exhibiting the highest AUC, positive likelihood ratio, and diagnostic odds ratio among biomarkers for CIN, followed by cystatin-C, and uKIM-1. These findings underscore the potential clinical utility of NGAL, cystatin-C and uKIM-1 in predicting and assessing CIN.Graphical Abstract (Source: European Journal of Medical Research)
Source: European Journal of Medical Research - April 1, 2024 Category: Research Source Type: research
Trajectories of Early Hemodynamic Changes After Heart Transplantation: The Evil is in the Details
Purpose: Hemodymamics is not included in the standard evaluation of graft function after heart transplantation (HT). We routinely perform right heart catheterization (RHC) at every endomyocardial biopsy (EMB). We sought to describe the potential longitudinal trajectories of hemodynamics through the first year after HT and analyze their relationship with subsequent cardiovascular outcomes. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Piermartiri, M. Scuppa, L. Giovannini, P. Prestinenzi, M. Silenzi, M. Sabatino, L. Borgese, S. Martin Suarez, L. Potena Source Type: research
Correlation between pressure gradient from echocardiography and peak-to-peak pressure gradient from cardiac catheterization or surgery in patients with coarctation of aorta
This study sought to establish the correlation and agreement between the systolic blood pressure (SBP) gradient between the upper and lower extremities, as well as, the mean and maximum PG derived from echocardiography, in comparison to the peak-to-peak pressure gradient obtained from either cardiac catheterization or surgery. We conducted a retrospective study on patients < 18 years diagnosed with coarctation at Chiang Mai University Hospital from 2011 to 2022. The study involved the measurement of the SBP gradient between the upper and lower extremities, mean and maximum PG using echocardiography, peak-to-peak p...
Source: The International Journal of Cardiovascular Imaging - April 1, 2024 Category: Radiology Source Type: research
Right Ventricular Contractile Reserve in Cardiopulmonary Diseases: A Simultaneous Hemodynamic and 3D Echocardiographic Study
Purpose: Right ventricular (RV) contractile reserve has been linked to exercise capacity and prognosis in cardiopulmonary diseases. However, evidence in this setting is limited, due to the complex shape and load dependency of the RV. We sought to study RV adaptation to exercise by simultaneous 3D echocardiography (3DE) and right heart catheterization (RHC). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , C. Dewachter, D. Muraru, G. Perego, M. Senni, L.P. Badano, G. Parati, J. Vachi éry, S. CARAVITA Source Type: research
Right Heart Reserve Function Assessed with Fluid Loading Test Predicts Late Right Heart Failure in Patients Undergoing Left Ventricular Assist Device Implantation
Purpose: A left ventricular assist device (LVAD) is an effective therapeutic option for advanced heart failure. Late right heart failure (LRHF) is a complication after LVAD implantation associated with increasing morbidity and mortality; however, the assessment of right heart function, including right heart reserve function after LVAD implantation, has not been established. We focused on a fluid loading test with right heart catheterization (RHC) to evaluate right heart pre-load reserve function and investigate its impact on LRHF. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , T. Kurihara, Y. Isotani, C. Bujo, J. Ishida, E. Amiya, M. Hatano, M. Kimura, S. Shimada, M. Ando, M. Ono, I. Komuro Source Type: research
Congenital Pulmonary Lymphangiectasia Masked by Postoperative Pulmonary Venous Obstruction in an Infant with Total Anomalous Pulmonary Venous Connection
Int Heart J. 2024;65(2):363-366. doi: 10.1536/ihj.23-232.ABSTRACTCongenital pulmonary lymphangiectasia (CPL) is associated with fetal pulmonary venous obstructive physiology. The precise morbidity of CPL is unknown as CPL is generally fatal in neonates. Here, we report an infant with secondary CPL in total anomalous pulmonary venous connection (TAPVC). He developed severe pulmonary hypertension (PH) after corrective surgery for TAPVC. However, cardiac catheterization showed mild left pulmonary venous obstruction (PVO), which was deemed unnecessary for re-intervention. He died at 11 months-old due to an exacerbation of PH. ...
Source: International Heart Journal - March 31, 2024 Category: Cardiology Authors: Yoshiko Nawata Daisuke Toyomura Seigo Okada Yasuo Suzuki Narumi Honda-Nakada Yuji Ohnishi Yuichiro Sugitani Naoki Kawaguchi Rui Tokitaka-Okada Naoki Masaki Eiji Ikeda Shunji Hasegawa Source Type: research
