Circ_0049271 targets the miR-1197/PTRF axis to attenuate the malignancy of osteosarcoma
CONCLUSIONS: Our findings revealed that circ_0049271 targeted the miR-1197/PTRF axis to attenuate the malignancy of OS, suggesting a potential target for its clinical treatment.PMID:38578882 | DOI:10.3233/CBM-230191 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - April 5, 2024 Category: Cancer & Oncology Authors: Yixin Wen Feng Xu Hui Zhang Source Type: research
Circ_0049271 targets the miR-1197/PTRF axis to attenuate the malignancy of osteosarcoma
CONCLUSIONS: Our findings revealed that circ_0049271 targeted the miR-1197/PTRF axis to attenuate the malignancy of OS, suggesting a potential target for its clinical treatment.PMID:38578882 | DOI:10.3233/CBM-230191 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - April 5, 2024 Category: Cancer & Oncology Authors: Yixin Wen Feng Xu Hui Zhang Source Type: research
Circ_0049271 targets the miR-1197/PTRF axis to attenuate the malignancy of osteosarcoma
CONCLUSIONS: Our findings revealed that circ_0049271 targeted the miR-1197/PTRF axis to attenuate the malignancy of OS, suggesting a potential target for its clinical treatment.PMID:38578882 | DOI:10.3233/CBM-230191 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - April 5, 2024 Category: Cancer & Oncology Authors: Yixin Wen Feng Xu Hui Zhang Source Type: research
Circ_0049271 targets the miR-1197/PTRF axis to attenuate the malignancy of osteosarcoma
CONCLUSIONS: Our findings revealed that circ_0049271 targeted the miR-1197/PTRF axis to attenuate the malignancy of OS, suggesting a potential target for its clinical treatment.PMID:38578882 | DOI:10.3233/CBM-230191 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - April 5, 2024 Category: Cancer & Oncology Authors: Yixin Wen Feng Xu Hui Zhang Source Type: research
Secondary hematological malignancies in patients with sarcoma: A single ‑center retrospective study
Oncol Lett. 2024 Mar 14;27(5):211. doi: 10.3892/ol.2024.14344. eCollection 2024 May.ABSTRACTThe present retrospective study investigated the clinical features and prognosis of secondary hematological malignancies (SHMs) in patients with sarcoma at Korea Cancer Center Hospital (Seoul, South Korea). Patients who had been diagnosed with SHMs after having received treatment for sarcoma between January 2000 and May 2023 were enrolled. Clinical data were collected from the patients' medical records. Clinical characteristics were analyzed, including SHM incidence, type and prognosis. Of 2,953 patients with sarcoma, 18 (0.6%) were...
Source: Oncology Letters - April 4, 2024 Category: Cancer & Oncology Authors: Yoon Jung Jang Hong Kyu Jeong Chang-Bae Kong Won Seok Song Wan Hyeong Cho Dae Geun Jeon Heyjin Kim Sung Hyun Yang Im Il Na Hyo-Rak Lee Hye Jin Kang Source Type: research
Osteosarcoma-targeted Cu and Ce based oxide nanoplatform for NIR II fluorescence/magnetic resonance dual-mode imaging and ros cascade amplification along with immunotherapy
As the lethal bone tumor, osteosarcoma often frequently occurs in children and adolescents with locally destructive and high metastasis. Distinctive kinds of nanoplatform with high therapeutical effect and pre... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 4, 2024 Category: Nanotechnology Authors: Mo Cheng, Qingjie Kong, Qing Tian, Weiluo Cai, Chunmeng Wang, Minjia Yuan, Wenxing Wang, Peiyuan Wang and Wangjun Yan Tags: Research Source Type: research
Comprehensive radiotherapy for pediatric Ewing Sarcoma: Outcomes of a prospective proton study
Patients with Ewing sarcoma (EWS) are treated with combination therapy, which includes radiation therapy (RT) as a treatment option for the primary tumor site (local control). Historically, the best local control (LC) outcomes have been achieved with surgery alone or combination of surgery with adjuvant RT for patients with high risk factors such as positive tumor margins after surgery or poor response to adjuvant/ induction chemotherapy. Definitive RT is often reserved for large tumors in anatomical locations where surgical resection is considered to be too morbid [1 –3]. (Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - April 4, 2024 Category: Radiology Authors: Julianna K. Bronk, Mary Frances McAleer, Susan L. McGovern, Yasmin Lassen-Ramshad, Akmal Safwat, Najat C. Daw, Nino Rainusso, Anita Mahajan, David R. Grosshans, Arnold C. Paulino Tags: Original Article Source Type: research
Cancer patterns in Arua district, Uganda: a hospital-based retrospective study
CONCLUSION: There is a high incidence of liver cancer in Arua district. The high levels of cervical, breast and oesophagus cancer were consistent with what is reported by the two PBCRs in Uganda. However, BL could be due to the presence of a BL treatment centre at Kuluva hospital in Arua. Cancer interventions in Arua should therefore be targeted towards liver, cervix, breast, and oesophagus cancer and furthering research on the reason for the high incidence of liver cancer.PMID:38566768 | PMC:PMC10984836 | DOI:10.3332/ecancer.2024.1688 (Source: Ecancermedicalscience)
Source: Ecancermedicalscience - April 3, 2024 Category: Cancer & Oncology Authors: Bridget Angucia Sharon Annet Nakaganda Geriga Fadhil Micah June Ezra Anecho Gilbert Aniku Amandua Jacinto Hesborn Wao Jackson Orem Onguru Daniel Source Type: research
CircPVT1 promotes migration and invasion by regulating miR-490-5p/HAVCR2 axis in osteosarcoma cells
This study aims to explore the molecular mechanism underlying the involvement of circPVT1 in osteosarcoma cells. We quantified circPVT1 expression using qRT-PCR in both control and osteosarcoma cell lines. To investigate the roles of circPVT1, miR-490-5p and HAVCR2 in vitro, we separately conducted overexpression and inhibition experiments for circPVT1, miR-490-5p and HAVCR2 in HOS and U2OS cells. Cell migration was assessed through wound healing and transwell migration assays, and invasion was measured via the Matrigel invasion assay. To elucidate the regulatory mechanism of circPVT1 in osteosarcoma, a comprehensive appro...
Source: J Cell Mol Med - April 3, 2024 Category: Molecular Biology Authors: Chunbin Zhou Lois Balmer Manshu Song Kezhou Wu Wei Wang Hu Wang Source Type: research
CircPVT1 promotes migration and invasion by regulating miR-490-5p/HAVCR2 axis in osteosarcoma cells
This study aims to explore the molecular mechanism underlying the involvement of circPVT1 in osteosarcoma cells. We quantified circPVT1 expression using qRT-PCR in both control and osteosarcoma cell lines. To investigate the roles of circPVT1, miR-490-5p and HAVCR2 in vitro, we separately conducted overexpression and inhibition experiments for circPVT1, miR-490-5p and HAVCR2 in HOS and U2OS cells. Cell migration was assessed through wound healing and transwell migration assays, and invasion was measured via the Matrigel invasion assay. To elucidate the regulatory mechanism of circPVT1 in osteosarcoma, a comprehensive appro...
Source: Molecular Medicine - April 3, 2024 Category: Molecular Biology Authors: Chunbin Zhou Lois Balmer Manshu Song Kezhou Wu Wei Wang Hu Wang Source Type: research
Cancer patterns in Arua district, Uganda: a hospital-based retrospective study
CONCLUSION: There is a high incidence of liver cancer in Arua district. The high levels of cervical, breast and oesophagus cancer were consistent with what is reported by the two PBCRs in Uganda. However, BL could be due to the presence of a BL treatment centre at Kuluva hospital in Arua. Cancer interventions in Arua should therefore be targeted towards liver, cervix, breast, and oesophagus cancer and furthering research on the reason for the high incidence of liver cancer.PMID:38566768 | PMC:PMC10984836 | DOI:10.3332/ecancer.2024.1688 (Source: Ecancermedicalscience)
Source: Ecancermedicalscience - April 3, 2024 Category: Cancer & Oncology Authors: Bridget Angucia Sharon Annet Nakaganda Geriga Fadhil Micah June Ezra Anecho Gilbert Aniku Amandua Jacinto Hesborn Wao Jackson Orem Onguru Daniel Source Type: research
