High trophinin-associated protein expression predicts good survival in acute myeloid leukemia with normal cytogenetics
CONCLUSION: TROAP could serve as an independent predictor of CN-AML patients and could act as a potential biomarker for the prognosis of CN-AML. TROAP expression levels were closely correlated with the drug sensitivity of multiple drugs.PMID:36938721 | DOI:10.3233/CBM-210042 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 20, 2023 Category: Cancer & Oncology Authors: Xue He Jing Hu Changjian Yan Xiaoni Liu Yali Zhao Ping Yang Jing Wang Shaoxiang Li Wei Zhang Gehong Dong Weilong Zhang Hongmei Jing Source Type: research

CPT1B, a metabolic molecule, is also an independent risk factor in CN-AML
CONCLUSION: CPT1B is a potential prognostic factor and a therapeutic target for AML treatment.PMID:36938722 | DOI:10.3233/CBM-210043 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 20, 2023 Category: Cancer & Oncology Authors: Qing Ling Shihui Mao Jiajia Pan Wenwen Wei Yu Qian Fenglin Li Shujuan Huang Wenle Ye Xiangjie Lin Jiansong Huang Jinghan Wang Jie Jin Source Type: research

Identification of therapeutic targets and prognostic biomarkers among CXC chemokines in hepatocellular carcinoma microenvironment
CONCLUSION: CXC chemokines might serve as therapeutic targets and prognostic biomarkers in HCC.PMID:36938723 | DOI:10.3233/CBM-210300 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 20, 2023 Category: Cancer & Oncology Authors: Zi Yin Tingting Ma Sheng Chen Min Yu Source Type: research

Age is a significant biomarker for the selection of neoadjuvant chemotherapy plus radiotherapy versus concurrent chemoradiotherapy in patients with advanced nasopharyngeal carcinoma
CONCLUSIONS: Age is a significant biomarker when selecting NACT + RT or CCRT alone in patients with advanced NPC.PMID:36938724 | DOI:10.3233/CBM-210357 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 20, 2023 Category: Cancer & Oncology Authors: Yihong Lin Xiongbin Yu Linbin Lu Hong Chen Junxian Wu Yaying Chen Qin Lin Xuewen Wang Xi Chen Xiong Chen Source Type: research

MKRN1/2 serve as tumor suppressors in renal clear cell carcinoma by regulating the expression of p53
CONCLUSIONS: Our study suggests that MKRN1 and MKRN2 serve as tumor suppressors in KIRC, and act as promising therapeutic targets for KIRC treatment.PMID:36938725 | DOI:10.3233/CBM-210559 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 20, 2023 Category: Cancer & Oncology Authors: Yun Yang Yanyan Luo Shuting Huang Yonghui Tao Chuanyin Li Chengcheng Wang Source Type: research

Rs9679162 genotype predicts prognosis of real-world advanced hepatocellular carcinoma treated by sorafenib
CONCLUSIONS: The GALNT14-rs9679162 "GG" genotype predicted shorter OS in patients with HBsAg-negative aHCC treated with sorafenib, but predicted a favorable response in all patients with aHCC treated with lenvatinib.PMID:36938726 | DOI:10.3233/CBM-220042 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 20, 2023 Category: Cancer & Oncology Authors: Chih-Lang Lin Rong-Nan Chien Li-Wei Chen Yu-De Chu Chau-Ting Yeh Source Type: research

The association between pain and WHO grade of pancreatic neuroendocrine neoplasms: A multicenter study
CONCLUSION: Abdominal or back pain is associated with the grade of PNENs. The nomograms based on clinical features may be a powerful numerical tool for predicting the grade of PNENs.PMID:36938727 | DOI:10.3233/CBM-220080 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 20, 2023 Category: Cancer & Oncology Authors: Cheng Wang Tingting Lin Xin Chen Wenjing Cui Chuangen Guo Zhongqiu Wang Xiao Chen Source Type: research

Prognostic value of an eighteen-genes panel in acute myeloid leukemia by analyzing TARGET and TCGA databases
CONCLUSIONS: This study evaluated a potential prognostic signature with eighteen genes and constructed a risk model significantly related to the prognosis of AML patients.PMID:36938728 | DOI:10.3233/CBM-220179 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 20, 2023 Category: Cancer & Oncology Authors: Panpan Chen Jiaming Cao Lingling Chen Guanfei Gao Yuanlin Xu Peijun Jia Yan Li Yating Li Jiangfeng Du Shijie Zhang Jingxin Zhang Source Type: research

ScRNA-seq revealed targeting regulator of G protein signaling 1 to mediate regulatory T cells in Hepatocellular carcinoma
CONCLUSIONS: Our findings suggested that RGS1 may regulate Treg function possibly through CXCR4 signaling and RGS1 could be a potential target to improve responses for immunotherapy in HCC.PMID:36938729 | DOI:10.3233/CBM-220226 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 20, 2023 Category: Cancer & Oncology Authors: Lianhong Zou Kaihua Liu Yongzhong Shi Guowei Li Haiyang Li Chaoxian Zhao Source Type: research

Construction and validation of a prognostic model based on ten signature cell cycle-related genes for early-stage lung squamous cell carcinoma
CONCLUSION: Our model predicted the prognosis of early-stage LSCC patients and demonstrated potential applications for clinical decision-making and individualized therapy.PMID:36938730 | DOI:10.3233/CBM-220227 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 20, 2023 Category: Cancer & Oncology Authors: Chengpeng Zhang Yong Huang Chen Fang Yingkuan Liang Dong Jiang Jiaxi Li Haitao Ma Wei Jiang Yu Feng Source Type: research

High trophinin-associated protein expression predicts good survival in acute myeloid leukemia with normal cytogenetics
CONCLUSION: TROAP could serve as an independent predictor of CN-AML patients and could act as a potential biomarker for the prognosis of CN-AML. TROAP expression levels were closely correlated with the drug sensitivity of multiple drugs.PMID:36938721 | DOI:10.3233/CBM-210042 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 20, 2023 Category: Cancer & Oncology Authors: Xue He Jing Hu Changjian Yan Xiaoni Liu Yali Zhao Ping Yang Jing Wang Shaoxiang Li Wei Zhang Gehong Dong Weilong Zhang Hongmei Jing Source Type: research

CPT1B, a metabolic molecule, is also an independent risk factor in CN-AML
CONCLUSION: CPT1B is a potential prognostic factor and a therapeutic target for AML treatment.PMID:36938722 | DOI:10.3233/CBM-210043 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 20, 2023 Category: Cancer & Oncology Authors: Qing Ling Shihui Mao Jiajia Pan Wenwen Wei Yu Qian Fenglin Li Shujuan Huang Wenle Ye Xiangjie Lin Jiansong Huang Jinghan Wang Jie Jin Source Type: research

Identification of therapeutic targets and prognostic biomarkers among CXC chemokines in hepatocellular carcinoma microenvironment
CONCLUSION: CXC chemokines might serve as therapeutic targets and prognostic biomarkers in HCC.PMID:36938723 | DOI:10.3233/CBM-210300 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 20, 2023 Category: Cancer & Oncology Authors: Zi Yin Tingting Ma Sheng Chen Min Yu Source Type: research

Age is a significant biomarker for the selection of neoadjuvant chemotherapy plus radiotherapy versus concurrent chemoradiotherapy in patients with advanced nasopharyngeal carcinoma
CONCLUSIONS: Age is a significant biomarker when selecting NACT + RT or CCRT alone in patients with advanced NPC.PMID:36938724 | DOI:10.3233/CBM-210357 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 20, 2023 Category: Cancer & Oncology Authors: Yihong Lin Xiongbin Yu Linbin Lu Hong Chen Junxian Wu Yaying Chen Qin Lin Xuewen Wang Xi Chen Xiong Chen Source Type: research

MKRN1/2 serve as tumor suppressors in renal clear cell carcinoma by regulating the expression of p53
CONCLUSIONS: Our study suggests that MKRN1 and MKRN2 serve as tumor suppressors in KIRC, and act as promising therapeutic targets for KIRC treatment.PMID:36938725 | DOI:10.3233/CBM-210559 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 20, 2023 Category: Cancer & Oncology Authors: Yun Yang Yanyan Luo Shuting Huang Yonghui Tao Chuanyin Li Chengcheng Wang Source Type: research