Researchers identify surface protein as a new osteosarcoma therapeutic target for antibody-drug conjugates
(University of Texas M. D. Anderson Cancer Center) A preclinical study shows an antibody-drug conjugate (ADC) targeting surface protein MT1-MMP can act as a guided missile in eradicating osteosarcoma tumor cells without damaging normal tissues. This technology, using precision therapy targeting of cell-surface proteins through a Bicycle toxin conjugate (BTC), shows encouraging results for the treatment of osteosarcoma. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 12, 2021 Category: Cancer & Oncology Source Type: news

Wireless interventional radiology firm Xenter announces formal launch
Xenter, a company developing wireless technology for use in interventional cardiology...Read more on AuntMinnie.comRelated Reading: FDA clears Philips SmartCT software for image-guided therapy RF ablation relieves pain for bone cancer patients in 3 days Study evaluates safety of new liver cancer treatment E/M coding and billing for interventional radiology Is uterine artery embolization underused for postpartum bleeding? (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - April 8, 2021 Category: Radiology Source Type: news

RF ablation relieves pain for bone cancer patients in 3 days
Radiofrequency (RF) ablation provides pain relief to patients whose cancer ha...Read more on AuntMinnie.comRelated Reading: Outpatient radiology procedure offers arthritis relief DC docs use MR-HIFU to treat bone tumor RF ablation for elderly NSCLC patients offers cost benefits Interventional techniques improve outcomes in colorectal liver metastases (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 26, 2021 Category: Radiology Source Type: news

Dog ’ s body size and shape could indicate a greater bone tumour risk
Osteosarcoma is a painful and aggressive bone tumour in dogs that is known to be more common in certain breeds than others. New research has now confirmed that larger breeds, such as Rottweiler, Great Dane and Rhodesian Ridgeback, have a greater risk of osteosarcoma than smaller breeds, as well as showing that breeds with shorter skulls and legs have lower osteosarcoma risk. The findings could inform future breed health reforms as well as studies into the way tumours develop from normal bone. (Source: University of Bristol news)
Source: University of Bristol news - March 10, 2021 Category: Universities & Medical Training Tags: International, Research; Faculty of Health Sciences, Faculty of Health Sciences, Bristol Veterinary School; Press Release Source Type: news

Bone Cancer Survivor Selected for SpaceX Flight
MONDAY, Feb. 22, 2021 -- Bone cancer survivor Hayley Arceneaux says her battle with the disease helped prepare her to serve as crew medical officer on a SpaceX flight later this year that is being used as a charitable fundraiser for St. Jude... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 22, 2021 Category: Pharmaceuticals Source Type: news

Bone cancer survivor to participate in first SpaceX private flight
Hayley Arceneaux, 29, will become youngest American in space when she joins Jared Isaacman and two contest winners on flightHayley Arceneaux, a 29-year-old physician assistant and former bone cancer patient, will become the youngest American in space later this year, when she participates in the first SpaceX private flight.St Jude Children ’s Research hospital in Memphis, Tennessee, where Arceneaux was once a patient and now works, announced on Monday that she will blast off later this year with the entrepreneur Jared Isaacman and two contest winners.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - February 22, 2021 Category: Science Authors: Associated Press in Memphis Tags: SpaceX Tennessee US news Science World news Source Type: news

Bone cancer survivor now relieves others ’ pain as orthopedic surgeon
For then-high school freshman Kevin Weiss, the pain in his knee started while doing something he loved — playing basketball. By spring, the pain he had while sprinting at track practice became too severe for this multi-sport athlete to ignore. After a trip to the doctor’s office and a subsequent X-ray, 15-year-old Weiss was diagnosed with osteosarcoma, one of the most common types of bone cancer , which tends to occur in children and teens. Osteosarcoma is also a fast-growing cancer that is… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - February 1, 2021 Category: Biotechnology Authors: Atrium Health Source Type: news

Bone cancer survivor now relieves others ’ pain as orthopedic surgeon
For then-high school freshman Kevin Weiss, the pain in his knee started while doing something he loved — playing basketball. By spring, the pain he had while sprinting at track practice became too severe for this multi-sport athlete to ignore. After a trip to the doctor’s office and a subsequent X-ray, 15-year-old Weiss was diagnosed with osteosarcoma, one of the most common types of bone cancer , which tends to occur in children and teens. Osteosarcoma is also a fast-growing cancer that is… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - February 1, 2021 Category: Pharmaceuticals Authors: Atrium Health Source Type: news

Predictors of Survival After Osteosarcoma
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - January 27, 2021 Category: Orthopaedics Tags: Trends and Innovations Source Type: news

Nixing bone cancer fuel supply offers new treatment approach, mouse study suggests
(Washington University School of Medicine) An innovative approach to treating bone tumors - starving cancer cells of the energy they need to grow - could one day provide an alternative to a commonly used chemotherapy drug without the risk of severe side effects, suggests a new study from Washington University School of Medicine in St. Louis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 26, 2021 Category: Cancer & Oncology Source Type: news

What Is the Survival Rate of Ewing Sarcoma
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - December 30, 2020 Category: General Medicine Source Type: news

It Happens Here: Marshfield ’ s Magical Moon Farm Needs Your Help
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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 30, 2020 Category: Consumer Health News Authors: CBS Boston Tags: Boston News Syndicated Local It Happens Here Magical Moon Farm Marshfield News Source Type: news

How Common Are Bone Spurs in Young Athletes?
Discussion The terminology of abnormal calcification of soft tissues and uses of the terms is often muddied. Especially as the causes may be similar and multiple adjacent tissues may be involved. An exostosis is an abnormal proliferation of bone from the joint. They can appear in various forms and in many locations. An osteophyte is also known as a bone spur and is type of exostosis. Osteophytes are thought to be periosteal or synovial mesenchymal stems cells that become calcified. They usually have a more narrow or pointed projection from the joint. Osteophytes are a very common feature of osteoarthritis. Enthesophytes a...
Source: PediatricEducation.org - November 30, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

What Causes Joint Pain?
DiscussionMusculoskeletal problems are common problems in pediatric practice with up to 15% of acute care visits being for this problem. Joint pain is a common concern for families but the differential diagnosis is extensive and needs thoughtful consideration. History is a key to discerning the potential diagnosis but also in guiding the physical examination and laboratory examination. Family history especially for systemic diseases should be considered. On physical examination all joints should be examined include sacroiliac and temporomandibular joints. Is this arthritis or arthralgia? Distinction between inflammatory...
Source: PediatricEducation.org - October 26, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Researchers uncover crucial gene for growth of Ewing sarcoma
(Center for Genomic Regulation) Researchers have discovered a gene that is critical for the development of Ewing sarcoma, a rare type of developmental cancer that presents in bones and soft tissues. Exploring the pharmacological inhibition of RING1B as a clinical therapy to treat Ewing sarcoma could open the door for new treatments for the rare disease. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 23, 2020 Category: Cancer & Oncology Source Type: news

UT Health San Antonio researcher, Scottish colleague, receive grant to study Ewing sarcoma
(University of Texas Health Science Center at San Antonio) While COVID-19 has become the top health priority around the world, a child is still diagnosed with cancer every two minutes globally. To meet the continuing need for pediatric cancer treatments, Alexander Bishop, DPhil, from The University of Texas Health San Antonio and Professor Kevin Hiom at the University of Dundee, Scotland, are teaming up to investigate a unique biological hallmark of Ewing sarcoma, R-loops. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 19, 2020 Category: Cancer & Oncology Source Type: news

The CNIO reprograms CRISPR system in mice to eliminate tumor cells without affecting healthy cells
(Centro Nacional de Investigaciones Oncol ó gicas (CNIO)) CNIO researchers destroyed Ewing's sarcoma and chronic myeloid leukaemia tumor cells by using CRISPR to cut out the fusion genes that cause them. For the first time, fusion genes have been selectively and efficiently removed using CRISPR. These genes are attracting a great deal of interest from the research community because they are unique to the tumor cell and are therefore excellent targets for the development of future drugs that only attack the tumor and are harmless for healthy cells. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 8, 2020 Category: Cancer & Oncology Source Type: news

Oncotarget: Exosomes secreted under hypoxia enhance stemness in Ewing's sarcoma
(Impact Journals LLC) The cover for issue 40 of Oncotarget features Figure 5, " miR-210 silences the proapoptosis member CASP8AP2, " by Kling, et al. which reported that hypoxic Ewing's sarcoma cells release exosomes that promote sphere formation, a stem-like phenotype, in EWS cells by enhancing survival. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 8, 2020 Category: Cancer & Oncology Source Type: news

New osteosarcoma treatment receives rare pediatric disease designation from the FDA
(Medical University of South Carolina) Innova Therapeutics Inc. recently announced that the U.S. Food and Drug Administration has granted rare pediatric disease designation for IVT-8086 for the treatment of osteosarcoma. MUSC Hollings Cancer Center researcher Nancy Klauber-DeMore, M.D., was instrumental in the development of the research that led to the therapy. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 2, 2020 Category: Cancer & Oncology Source Type: news

Woman receives successful treatment for rare cancer in Charlotte
Jo Ellen Marrow was diagnosed with a rare tissue cancer called sarcoma in March 2020. She went to Levine Cancer Institute, ranked nationally by U.S. News& World Report, for treatments. Using a mixture of both virtual and in-person care due to COVID-19, she was able to receive treatment to achieve a successful recovery. Learn more about the sarcoma and bone cancer program at Levine Cancer Institute. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - October 1, 2020 Category: Biotechnology Authors: Atrium Health Source Type: news

Researchers use soy to improve bone cancer treatment
(Washington State University) Researchers showed that the slow release of soy-based chemical compounds from a 3D-printed bone-like scaffold resulted in a reduction in bone cancer cells while building up healthy cells and reducing harmful inflammation. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 15, 2020 Category: Cancer & Oncology Source Type: news

ASBMR 2020: Sequential Osteoporosis Meds, AI, Bone Cancer, and More ASBMR 2020: Sequential Osteoporosis Meds, AI, Bone Cancer, and More
The virtual meeting will provide the latest information about basic research and clinical treatment of bone disease, from sequential osteoporosis therapy to AI to bone cancer.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - September 9, 2020 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Where does bone cancer usually start?
Title: Where does bone cancer usually start?Category: Diseases and ConditionsCreated: 8/6/2020 12:00:00 AMLast Editorial Review: 8/6/2020 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - August 6, 2020 Category: Cancer & Oncology Source Type: news

New Research Shows Dinosaurs Suffered From Malignant Cancer, Too
Scientists have identified an aggressive bone cancer — for the first time — in the fibula of a dinosaur that lived 76 to 77 million years ago. The diagnosis sheds new light on dinosaurs and disease.(Image credit: Sergey Krasovskiy/Stocktrek Images/Getty Images) (Source: NPR Health and Science)
Source: NPR Health and Science - August 4, 2020 Category: Consumer Health News Authors: Elena Burnett Source Type: news

Aggressive Cancer Diagnosed for First Time in a Dinosaur
TUESDAY, Aug. 4, 2020 -- Scientists for the first time have identified an aggressive bone cancer in a dinosaur that lived nearly 77 million years ago. The cancerous lower leg bone (fibula) is from a horned dinosaur called a Centrosaurus apertus. At... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 4, 2020 Category: General Medicine Source Type: news

Malignant cancer diagnosed in a dinosaur for the first time
(Royal Ontario Museum) A collaboration led by the Royal Ontario Museum (ROM) and McMaster University has led to the discovery and diagnosis of an aggressive malignant bone cancer -- an osteosarcoma -- for the first time ever in a dinosaur. No malignant cancers (tumours that can spread throughout the body and have severe health implications) have ever been documented in dinosaurs previously. The paper was published in The Lancet Oncology. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 3, 2020 Category: Cancer & Oncology Source Type: news

Stand Up To Cancer awards $1.1 million in grants to research teams
(Stand Up To Cancer) Stand Up To Cancer announced today five new awards that will cut across institutional and national lines to foster collaborative research and explore new paths to improve cancer treatment. The projects will receive a combined total of $1.1 million in funding to address some of the most pressing questions associated with colorectal, Ewing sarcoma, pancreatic, lung and pediatric cancers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 29, 2020 Category: International Medicine & Public Health Source Type: news

MU advances chemotherapy-free treatment for cancer in animals and humans
(University of Missouri-Columbia) Osteosarcoma, a common bone cancer in dogs, affects more than 10,000 dogs in the US each year. While chemotherapy is generally effective at killing some of the cancer cells, the numerous side effects can be painful and often a subset of cancer cells exist that are resistant to chemotherapy. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 17, 2020 Category: Cancer & Oncology Source Type: news

Finding hints at novel target for Ewing sarcoma therapy
(University of Texas Health Science Center at San Antonio) A genetic code-reading machine that is overactive in the pediatric cancer Ewing sarcoma causes cell structures called nucleoli to break up, researchers found. A team at UT Health San Antonio's Greehey Children's Cancer Research Institute will study how to take advantage of this finding therapeutically. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 16, 2020 Category: International Medicine & Public Health Source Type: news

Scientists discover way to stop spread of devastating childhood cancer
(University of East Anglia) New research reveals a new way to stop the spread of bone cancer in children.The discovery is thought to be the most important breakthrough in the field for more than 40 years.The researchers say their work could lead to 'kinder' treatments for children with bone cancer and save lives. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 15, 2020 Category: International Medicine & Public Health Source Type: news

Journal of Dental Research study: Fluoridation is not associated with increase in osteosarcoma
(International& American Associations for Dental Research) The Journal of Dental Research published today the results of a study that demonstrated that community water fluoridation is not associated with increased risk of osteosarcoma. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 12, 2020 Category: International Medicine & Public Health Source Type: news

Bone Cancer FAQ
True bone cancer is uncommon, but cancer can also spread to bones from other parts of the body. Learn the difference and how bone cancer is diagnosed and treated. (Source: WebMD Health)
Source: WebMD Health - May 6, 2020 Category: Consumer Health News Source Type: news

E-scooter  - a new source of danger in tumor endoprosthetics - den Toom DA, Bockholt S, Gosheger G, Budny T, Deventer N, Lübben T, Schneider KN.
A  24-year-old male patient who suffered a periprosthetic fracture of the left distal femur due to an e‑scooter accident was referred to the outpatient department of tumor orthopedics. The patient had been diagnosed with Ewing's sarcoma of the left prox... (Source: SafetyLit)
Source: SafetyLit - March 25, 2020 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news

NIH study provides genetic insights into osteosarcoma in children
Osteosarcoma is the most common cancerous bone tumor of children and adolescents. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - March 19, 2020 Category: American Health Source Type: news

NIH study provides genetic insights into osteosarcoma in children
(NIH/National Cancer Institute) A study by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, offers new insight into genetic alterations associated with osteosarcoma, the most common cancerous bone tumor of children and adolescents. The researchers found that more people with osteosarcoma carry harmful, or likely harmful, variants in known cancer-susceptibility genes than people without osteosarcoma. This finding has implications for genetic testing of children with osteosarcoma, as well as their families. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 19, 2020 Category: Cancer & Oncology Source Type: news

Tumor Profiling Yields Insights Into Poor Osteosarcoma Response to Immunotherapy Tumor Profiling Yields Insights Into Poor Osteosarcoma Response to Immunotherapy
Multiple genetic and cellular factors contribute to osteosarcoma's poor response to immunotherapy, researchers say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 3, 2020 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Profiling of Osteosarcoma Demonstrates Why Immunotherapy is Ineffective
Researchers found that poor infiltration of the tumor by immune cells, low activity from available T-cells, a lack of immune-stimulating neoantigens, and multiple immune-suppressing pathways all combine to dampen responses to immunotherapy in this disease landscape. (Source: CancerNetwork)
Source: CancerNetwork - February 25, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

'The companionship is lovely': The bond between the dying and their companions is truly unique
David Parkes, 58, from Bradford, has terminal kidney and bone cancer, and Michelle Craven is a mother-of-two who volunteers as his Marie Curie end-of-life companion. (Source: the Mail online | Health)
Source: the Mail online | Health - February 25, 2020 Category: Consumer Health News Source Type: news

Osteosarcoma profiling reveals why immunotherapy remains ineffective
(University of Texas M. D. Anderson Cancer Center) Comprehensive profiling of tumor samples taken from patients with osteosarcoma shows that multiple factors contribute to the traditionally poor responses observed from treatment with immune checkpoint inhibitors, according to new research from The University of Texas MD Anderson Cancer Center. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 21, 2020 Category: Cancer & Oncology Source Type: news

Mother could give birth to her own GRANDCHILD
Jasmine Bowley, 21, from Norwich, had her ovaries and Fallopian tubes removed when she developed pelvic Ewing's sarcoma aged seven - which also affected her womb. (Source: the Mail online | Health)
Source: the Mail online | Health - February 18, 2020 Category: Consumer Health News Source Type: news

Schoolgirl, nine, beat bone cancer after doctors amputated and reattached her leg BACKWARDS
Amelia Eldred, nine, from Tamworth, Staffordshire, was diagnosed with osteosarcoma, a common type of bone cancer, in August 2017. (Source: the Mail online | Health)
Source: the Mail online | Health - January 16, 2020 Category: Consumer Health News Source Type: news

New limb for girl who 'danced her foot off'
Tamworth girl Amelia Eldred lost a limb to bone cancer and had a leg reattached backwards. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - December 31, 2019 Category: Consumer Health News Source Type: news

Combination of chemo and diabetes drugs shows potential for treating Ewing sarcoma
(Houston Methodist) Houston Methodist researchers propose a combination of two well-known drugs as a new treatment option for Ewing sarcoma -- one of them typically used to treat diabetes. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 16, 2019 Category: Cancer & Oncology Source Type: news

SP-2577 Granted Fast Track Designation by the FDA for Patients with Ewing Sarcoma
The drug is currently the subject of an ongoing phase I/II clinical study for the treatment of patients with Ewing sarcoma who have relapsed or are refractory to standard-of-care therapy. (Source: CancerNetwork)
Source: CancerNetwork - December 16, 2019 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Jack Savoretti messages cancer girl Anna Drysdale
Anna Drysdale, 8, contracted osteosarcoma at five and says getting the singer's message was "amazing". (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - December 2, 2019 Category: Consumer Health News Source Type: news

Medical News Today: Ewing sarcoma: What to know
Ewing sarcoma is a rare form of bone cancer that most commonly affects children and teenagers. In this article, learn about the symptoms, causes, and treatment options. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 24, 2019 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Boy, seven, who lost his leg due to cancer gets knee made using his FOOT
Austin Degnan, of Illinois, was diagnosed with osteosarcoma earlier this year, after complaining of a severe pain in his left leg. He underwent a surgical procedure called a rotationplasty. (Source: the Mail online | Health)
Source: the Mail online | Health - October 11, 2019 Category: Consumer Health News Source Type: news

Canon-Mac parents want deeper investigation of suspected childhood cancer cluster
Holding the funeral-home portrait of her son Curtis who died in 2011 from Ewing's sarcoma, Cindy Valent came to a hearing Monday night about the suspected cancer cluster in Washington County with a direct request: Find out why so many youth in southwestern Pennsylvania have contracted the rare and deadly form of cancer, and whether it has anything to do with the natural gas industry. Valent, who now lives in Beaver County, used to live in Cecil less than a mile from two other youth with Ewing's.… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - October 8, 2019 Category: Pharmaceuticals Authors: Paul J. Gough Source Type: news

Canon-Mac parents want deeper investigation of suspected childhood cancer cluster
Holding the funeral-home portrait of her son Curtis who died in 2011 from Ewing's sarcoma, Cindy Valent came to a hearing Monday night about the suspected cancer cluster in Washington County with a direct request: Find out why so many youth in southwestern Pennsylvania have contracted the rare and deadly form of cancer, and whether it has anything to do with the natural gas industry. Valent, who now lives in Beaver County, used to live in Cecil less than a mile from two other youth with Ewing's.… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - October 8, 2019 Category: Biotechnology Authors: Paul J. Gough Source Type: news

Texas boy, 10, battling a rare bone cancer walks just hours after having his leg amputated
Bryan Marquez, 10, from San Antonio, Texas, started having trouble walking and was limping. He was diagnosed this year with a rare bone cancer known as Ewing sarcoma. (Source: the Mail online | Health)
Source: the Mail online | Health - September 23, 2019 Category: Consumer Health News Source Type: news