Correlation of Serum Lactate Levels, Perfusion Index and Plethysmography Variability Index With Invasive Blood Pressure in Late Preterm and Term Infants With Shock
CONCLUSION: PI has moderate positive correlation while SL and PVI have moderate negative correlation with invasive blood pressure. The cutoff values of SL ≥4.65, PI <0.45 and PVI ≥23.5 can predict invasive hypotension with good sensitivity and negative predictive value.PMID:36756997 (Source: Indian Pediatrics)
Source: Indian Pediatrics - February 9, 2023 Category: Pediatrics Authors: Shyam Sundar Sharma Chandra Kumar Natarajan C Shanmugasundaram Vaanathi Hementha Kumar Giriraj Kumar Source Type: research
Correlation of Serum Lactate Levels, Perfusion Index and Plethysmography Variability Index With Invasive Blood Pressure in Late Preterm and Term Infants With Shock
CONCLUSION: PI has moderate positive correlation while SL and PVI have moderate negative correlation with invasive blood pressure. The cutoff values of SL ≥4.65, PI <0.45 and PVI ≥23.5 can predict invasive hypotension with good sensitivity and negative predictive value.PMID:36756997 (Source: Indian Pediatrics)
Source: Indian Pediatrics - February 9, 2023 Category: Pediatrics Authors: Shyam Sundar Sharma Chandra Kumar Natarajan C Shanmugasundaram Vaanathi Hementha Kumar Giriraj Kumar Source Type: research
Correlation of Serum Lactate Levels, Perfusion Index and Plethysmography Variability Index With Invasive Blood Pressure in Late Preterm and Term Infants With Shock
CONCLUSION: PI has moderate positive correlation while SL and PVI have moderate negative correlation with invasive blood pressure. The cutoff values of SL ≥4.65, PI <0.45 and PVI ≥23.5 can predict invasive hypotension with good sensitivity and negative predictive value.PMID:36756997 (Source: Indian Pediatrics)
Source: Indian Pediatrics - February 9, 2023 Category: Pediatrics Authors: Shyam Sundar Sharma Chandra Kumar Natarajan C Shanmugasundaram Vaanathi Hementha Kumar Giriraj Kumar Source Type: research
Unlucky numbers: Fighting murder convictions that rest on shoddy stats
LEIDEN, THE NETHERLANDS—
When a Dutch nurse named Lucia de Berk stood trial for serial murder in 2003, statistician Richard Gill was aware of the case. But he saw no reason to stick his nose into it.
De Berk was a pediatric nurse at Juliana Children’s Hospital in The Hague. In 2001, after a baby died while she was on duty, a colleague told superiors that De Berk had been present at a suspiciously high number of deaths and resuscitations. Hospital staff immediately informed the police. When investigators reexamined records from De Berk’s shifts, they found 10 suspicious incidents. Three other hospitals wher...
Source: Science of Aging Knowledge Environment - January 19, 2023 Category: Geriatrics Source Type: research
Taliban ban on female NGO staff is deepening Afghanistan ’s public health crisis
The Taliban’s 24 December 2022 decree barring women from working in national and international non-governmental organizations (NGOs) is another devastating blow to women’s rights in Afghanistan. It also threatens to plunge a country beset by hunger and natural disasters even deeper into
a
public health crisis.
The United Nations (UN) and its humanitarian partners are engaged in intense negotiations to persuade the Taliban to reverse the edict. But for now, many NGOs, which depend heavily on female staff, have made the heart-wrenching decision to suspend their operations, which provide vital food, hygien...
Source: Science of Aging Knowledge Environment - January 16, 2023 Category: Geriatrics Source Type: research
Moms ’ mitochondria may refresh cells in sick kids
A gift from their mothers might
reenergize the cells of children who carry faulty mitochondria
, the organelles that serve as cells’ power plants. A research team is testing a strategy that involves soaking patients’ blood cells in a broth of healthy mitochondria from their mothers and then reinfusing them. Early signs suggest the intervention is safe and may improve the children’s health and development, and the researchers are planning a follow-up clinical trial.
This approach “is different from what anyone else is doing,” says Mary Kay Koenig, a pediatric neurologist at the University of Texas ...
Source: Science of Aging Knowledge Environment - December 21, 2022 Category: Geriatrics Source Type: research
Umbilical cord thrombosis and chorioamnionitis in neonatal arterial ischaemic stroke
A baby boy was delivered at term by emergency caesarean section because of abnormal fetal heart rate patterns during spontaneous labour. The umbilical cord arterial blood obtained at delivery had a pH of 6.97 and a lactate concentration of 12.1 mmol/L. The Apgar scores were 3 and 7, respectively, at 1 and 5 min. The proximal umbilical cord had a thrombotic aspect at delivery (figure 1). A thrombus was also identified in the ductus venosus at 1 hour of life. The boy presented left hemicorporeal seizures at 21 hours of life, which revealed a neonatal arterial ischaemic stroke (NAIS; figure 2). Placental histology revealed ac...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - December 15, 2022 Category: Perinatology & Neonatology Authors: Dridi, M., Chabrier, S., Raia-Barjat, T., Giraud, A. Tags: Open access Images in neonatal medicine Source Type: research
Amniotic fluid embolism ‐induced cardiopulmonary collapse successfully treated with combination VA‐ECMO and Impella CP
We present a case of AFE resulting in cardiopulmonary collapse and subsequent cardiac arrest where we were able to safely deliver the baby and resuscitate the mother with veno-arterial extracorporeal membrane oxygenation and Impella CP —a novel combination known as ECPELLA. We discuss the implications of this approach as a more efficacious strategy in resuscitating AFE-induced cardiogenic shock and arrest. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 8, 2022 Category: Cardiology Authors: Hafez Golzarian,
Alaha Mariam,
Sidra R. Shah,
Benjamin A. Pasley,
Syed H. Haq,
Anne R. Edgerton,
William E. Scherger,
Vanessa L. Stallkamp,
Dennis Patel,
Amanda Laird,
William C. Cole,
Sandeep M. Patel Tags: Case Report Source Type: research
Closed versus open endotracheal tube suction in mechanically ventilated neonates: a randomized controlled trial
Conclusion: In a unit with a low incidence of VAP, the effect of the endotracheal suction method alone did not impact the occurrence of VAP in the study population.Clinical trial registration: CTRI/2020/03/023679; Date: 17.02.2020.What is Known:• Better physiological stability of the closed-suctioning method on short-term measures including noticeably fewer episodes of hypoxia, a smaller drop in TcPO2 levels, and less variability in heart rate and bradycardia episodes.What is New:• In a unit with a low incidence of VAP in the neonates, randomized control trial studying the effect of the endotracheal suction method alon...
Source: European Journal of Pediatrics - December 8, 2022 Category: Pediatrics Source Type: research
Buprenorphine Associated With Fewer Birth Risks Than Methadone During Pregnancy
Pregnant people with opioid use disorder who are treated with buprenorphine may experience a lower risk of neonatal complications (such as preterm birth) than those taking methadone, according to astudy in theNew England Journal of Medicine. The study did not reveal differences in maternal outcomes (such as caesarean section) between the two groups, however.“The standard care for treating pregnant persons with opioid use disorder is opioid agonist therapy with buprenorphine or methadone, which is associated with improved adherence to prenatal care, lower incidence of preterm birth, reduced return to opioid use, and fewer...
Source: Psychiatr News - December 5, 2022 Category: Psychiatry Tags: buprenorphine caesarean section low birth weight maternal outcomes Medicaid metadone neonatal outcomes New England Journal of Medicine opioid use disorder pregnancy Source Type: research
Social inequities hurt babies' hearts: a commentary on Forero-Manzano, MJ, et al
Pediatr Res. 2022 Dec 2. doi: 10.1038/s41390-022-02363-7. Online ahead of print.NO ABSTRACTPMID:36460740 | DOI:10.1038/s41390-022-02363-7 (Source: Pediatric Research)
Source: Pediatric Research - December 2, 2022 Category: Pediatrics Authors: Luz Claudio Juan Antonio Ortega Laura Andrea Rodr íguez Villamizar Source Type: research
Social inequities hurt babies' hearts: a commentary on Forero-Manzano, MJ, et al
Pediatr Res. 2022 Dec 2. doi: 10.1038/s41390-022-02363-7. Online ahead of print.NO ABSTRACTPMID:36460740 | DOI:10.1038/s41390-022-02363-7 (Source: Pediatric Research)
Source: Pediatric Research - December 2, 2022 Category: Pediatrics Authors: Luz Claudio Juan Antonio Ortega Laura Andrea Rodr íguez Villamizar Source Type: research
Commentary: Emergent arterial switch for critically ill babies with transposition
Among the most important advances over the past 2 decades in the field of congenital heart surgery has been the development and refinement of emergency extracorporeal membrane oxygenation (ECMO). Whether dealing with cardiac arrest after surgery or arrival in the middle of the night of an undiagnosed neonate, generic arteriovenous ECMO smoothly i nstituted by a coordinated experienced team has become the hallmark of every high quality, busy congenital program. ECMO allows for stabilization, thoughtful and accurate diagnosis, and time to develop a longer-term plan. (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - November 30, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Richard A. Jonas Tags: Commentary Source Type: research
Calculation of absorbed dose in paediatric phantoms using Monte Carlo techniques for < sup > 18 < /sup > F-FDG and < sup > 99m < /sup > Tc-DMSA and the new TIAC
In this study, new dosimetric data were calculated using Baby and Child phantoms and the newly recommended TIAC.PMID:36401987 | DOI:10.1016/j.apradiso.2022.110526 (Source: Applied Radiation and Isotopes)
Source: Applied Radiation and Isotopes - November 19, 2022 Category: Radiology Authors: Carlos V G Ferreira Bruno M Mendes Lucas Paix ão Thiago V M Lima Ralph Santos-Oliveira Telma C F Fonseca Source Type: research
Calculation of absorbed dose in paediatric phantoms using Monte Carlo techniques for < sup > 18 < /sup > F-FDG and < sup > 99m < /sup > Tc-DMSA and the new TIAC
In this study, new dosimetric data were calculated using Baby and Child phantoms and the newly recommended TIAC.PMID:36401987 | DOI:10.1016/j.apradiso.2022.110526 (Source: Applied Radiation and Isotopes)
Source: Applied Radiation and Isotopes - November 19, 2022 Category: Radiology Authors: Carlos V G Ferreira Bruno M Mendes Lucas Paix ão Thiago V M Lima Ralph Santos-Oliveira Telma C F Fonseca Source Type: research
