Epicardial pacing lead implantation for congenital complete atrioventricular block immediately after birth: a case report
ConclusionThe infant with a congenital complete atrioventricular block was rescued by an uneventful epicardial lead implantation. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - November 1, 2023 Category: General Medicine Source Type: research

Awake craniotomy during pregnancy: A systematic review of the published literature
AbstractNeurosurgical pathologies in pregnancy pose significant complications for the patient and fetus, and physiological stressors during anesthesia and surgery may lead to maternal and fetal complications. Awake craniotomy (AC) can preserve neurological functions while reducing exposure to anesthetic medications. We reviewed the literature investigating AC during pregnancy. PubMed, Scopus, and Web of Science databases were searched from the inception to February 7th, 2023, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. Studies in English investigating AC in pregnant ...
Source: Neurosurgical Review - November 1, 2023 Category: Neurosurgery Source Type: research

Pulse Oximetry Screening for Critical Congenital Heart Defects in Newborn Babies
Pulse oximetry screening (POS) was first described over 20 years ago. However, in recent years, major clinical trials have demonstrated consistent test accuracy for the detection of critical congenital heart defects (CCHD). International uptake of POS has progressed well over the last 10 years with most major high-income countries now recommending screening. This review describes the evidence base which has led to this, the current debate regarding choice of screening algorithm, and the future areas for further research. (Source: Critical Care Nursing Clinics of North America)
Source: Critical Care Nursing Clinics of North America - October 17, 2023 Category: Nursing Authors: Anurag Ghirdar, Andrew K. Ewer Source Type: research

Looking at a baby's heart through the lens of the mother's blood
EMBO Mol Med. 2023 Oct 16:e18680. doi: 10.15252/emmm.202318680. Online ahead of print.ABSTRACTCongenital heart disease (CHD) comprises several cardiovascular abnormalities existing from birth. Cardiac defects range from minor asymptomatic lesions to potentially life-threatening situations. Early fetal echocardiography, the gold standard for the in-utero diagnosis of CHD, is inaccurate at identifying defects in pulmonary veins and atrioventricular valves or lesions that occur later or progress during pregnancy. In this issue of EMBO Molecular Medicine, Yin et al report new proteomic data on maternal blood samples and a nove...
Source: Molecular Medicine - October 16, 2023 Category: Molecular Biology Authors: Paolo Madeddu Source Type: research

Looking at a baby's heart through the lens of the mother's blood
EMBO Mol Med. 2023 Oct 16:e18680. doi: 10.15252/emmm.202318680. Online ahead of print.ABSTRACTCongenital heart disease (CHD) comprises several cardiovascular abnormalities existing from birth. Cardiac defects range from minor asymptomatic lesions to potentially life-threatening situations. Early fetal echocardiography, the gold standard for the in-utero diagnosis of CHD, is inaccurate at identifying defects in pulmonary veins and atrioventricular valves or lesions that occur later or progress during pregnancy. In this issue of EMBO Molecular Medicine, Yin et al report new proteomic data on maternal blood samples and a nove...
Source: Molecular Medicine - October 16, 2023 Category: Molecular Biology Authors: Paolo Madeddu Source Type: research

Triple repeated fetal congenital heart disease linked to PLD1 mutation: a case report
ConclusionsThis report is consistent with previous reports that mutations inPLD1 cause right ventricular valve dysplasia. However, there have been few case reports ofPLD1 mutations, and we hope that this report will contribute to elucidate the causes of congenital heart disease, especially right ventricular valve dysplasia, and that the accumulation of such information will provide more detailed information onPLD1 mutations in heart disease. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - September 29, 2023 Category: General Medicine Source Type: research

News at a glance: China ’s S & T clusters, abundant fairy circles, and Arecibo ’s next chapter
BIOGEOGRAPHY Fairy circles abound in dry regions of many countries Mysterious patches of vegetation called fairy circles are well documented in the drylands of Australia and Namibia. Now, a study that combines machine learning and satellite images that span the continents reports examples in 13 other countries, mainly in Africa . Many of the 263 sites identified—in the Sahara and Madagascar, for example—have never before been recorded by scientists. Fairy circles consist of a ring of tall grass surrounding a patch of bare soil up to 12 meters in diameter. Researchers have attributed th...
Source: Science of Aging Knowledge Environment - September 28, 2023 Category: Geriatrics Source Type: research

Caring for the hypertensive newborn: a prospective evaluation of risk factors, clinical profile, management, and predictors of outcome of neonatal hypertension
Conclusion:  NHT is a clinically important but underrecognised entity. Hypertension was seen in preterm, low birth weight neonates and associated with certain maternal and postnatal risk factors, with majority responding to a single drug. Neonates with multiple comorbid illnesses need careful monitoring for h ypertension as they are at a higher risk of developing hypertensive crisis. Most NHT cases were normotensive at the time of discharge and did not require pharmacotherapy beyond the neonatal period.What is Known:• Neonatal hypertension (NHT) is an under-recognised entity, and the spectrum of clinical presentation ...
Source: European Journal of Pediatrics - September 23, 2023 Category: Pediatrics Source Type: research

Prediction of labour outcomes using prelabour computerised cardiotocogram and maternal and fetal Doppler indices: A  prospective cohort study
CONCLUSIONS: In pregnant women admitted in latent phase of labour or for induction of labour at term, prelabour cCTG STV had a weakly positive association with umbilical cord arterial pH but was not predictive of emergency delivery due to pathological CTG during labour.PMID:37718558 | DOI:10.1111/1471-0528.17669 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 18, 2023 Category: OBGYN Authors: Sakita Moungmaithong Michelle Sung Nga Lam Angel Hoi Wan Kwan Sani Tsz Kei Wong Ada Wing Ting Tse Daljit Singh Sahota Sin Ting Angela Tai Liona Chiu Yee Poon Source Type: research

Prediction of labour outcomes using prelabour computerised cardiotocogram and maternal and fetal Doppler indices: A  prospective cohort study
CONCLUSIONS: In pregnant women admitted in latent phase of labour or for induction of labour at term, prelabour cCTG STV had a weakly positive association with umbilical cord arterial pH but was not predictive of emergency delivery due to pathological CTG during labour.PMID:37718558 | DOI:10.1111/1471-0528.17669 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 18, 2023 Category: OBGYN Authors: Sakita Moungmaithong Michelle Sung Nga Lam Angel Hoi Wan Kwan Sani Tsz Kei Wong Ada Wing Ting Tse Daljit Singh Sahota Sin Ting Angela Tai Liona Chiu Yee Poon Source Type: research

Electrocardiographic characteristics of newborns with ventricular septal defects: a Copenhagen Baby Heart Study
Conclusion: Newborns with VSDs showed significant differences inQRS axis, andR- andS-wave precordial amplitudes compared to matched controls. Perimembranous and large VSDs had the greatest effect on the neonatal ECG.What is Known:• Ventricular septal defects in newborns are prevalent and may affect cardiac function and structure.What is New:• The Copenhagen Baby Heart Study is the largest study including a cohort of unselected newborns undergoing postnatal cardiac examination.• We found that newborns with VSD showed significant electrocardiographic differences depending on size and type of VSD compared with healthy n...
Source: European Journal of Pediatrics - September 11, 2023 Category: Pediatrics Source Type: research

Becoming ‘Super Fontan’: Is slim and athletic the best prescription to improve prognosis in patients with Fontan circulation?
More than half of century has passed since the first Fontan procedure was performed as a surgical intervention to palliate babies born with tricuspid atresia (first performed in 1968). By redirecting venous return directly to the pulmonary arteries and creating a univentricular circulation without a sub-pulmonary ventricle, thousands of children around the world, born with the most complex underlying heart defects not amenable to biventricular repair, where able to survive and reach adulthood [1]. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - August 18, 2023 Category: Cardiology Authors: Ioannis Kasouridis, Isma Rafiq, Margarita Brida Tags: Editorial Source Type: research

Adverse Maternal and Perinatal Outcomes of Meconium-Stained Amniotic Fluid in Term Labor at Hospitals in South Gondar Zone, Northwest Ethiopia: A Prospective Cohort Study
CONCLUSION: Meconium-stained amniotic fluid significantly increased adverse maternal and perinatal outcomes in Ethiopia. The risk of perinatal asphyxia, nonreassuring fetal heart rate pattern, neonatal sepsis, meconium aspiration syndrome, admission to the NICU, early neonatal death, operative delivery, and puerperal sepsis were significantly higher in meconium-exposed groups. Special attention should be given to meconium-exposed mothers during the intrapartum period and in postnatal follow-up.PMID:37576998 | PMC:PMC10421705 | DOI:10.1155/2023/8725161 (Source: Biomed Res)
Source: Biomed Res - August 14, 2023 Category: Research Authors: Dagne Addisu Maru Mekie Source Type: research

Adverse Maternal and Perinatal Outcomes of Meconium-Stained Amniotic Fluid in Term Labor at Hospitals in South Gondar Zone, Northwest Ethiopia: A Prospective Cohort Study
CONCLUSION: Meconium-stained amniotic fluid significantly increased adverse maternal and perinatal outcomes in Ethiopia. The risk of perinatal asphyxia, nonreassuring fetal heart rate pattern, neonatal sepsis, meconium aspiration syndrome, admission to the NICU, early neonatal death, operative delivery, and puerperal sepsis were significantly higher in meconium-exposed groups. Special attention should be given to meconium-exposed mothers during the intrapartum period and in postnatal follow-up.PMID:37576998 | PMC:PMC10421705 | DOI:10.1155/2023/8725161 (Source: Biomed Res)
Source: Biomed Res - August 14, 2023 Category: Research Authors: Dagne Addisu Maru Mekie Source Type: research

Serum ADAMTS-9 Level in Newborn Babies with Congenital Heart Disease
Conclusion In conclusion, it was found that the serum ADAMTS-9 levels were significantly higher in newborns with CHD than in healthy newborns. In parallel, ADAMTS-9 levels above a certain cut-off value were associated with CHD. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - August 14, 2023 Category: Perinatology & Neonatology Authors: Becerir, Cem Tayman, C üneyt Kurt, Abdullah Çakır, Ufuk Koyuncu, İsmail Ceran, Burak Toprak, Kenan K ızılgün, Murat Tags: Original Article Source Type: research