RNA binding proteins in cardiovascular development and disease
Curr Top Dev Biol. 2024;156:51-119. doi: 10.1016/bs.ctdb.2024.01.007. Epub 2024 Mar 15.ABSTRACTCongenital heart disease (CHD) is the most common birth defect affecting>1.35 million newborn babies worldwide. CHD can lead to prenatal, neonatal, postnatal lethality or life-long cardiac complications. RNA binding protein (RBP) mutations or variants are emerging as contributors to CHDs. RBPs are wizards of gene regulation and are major contributors to mRNA and protein landscape. However, not much is known about RBPs in the developing heart and their contributions to CHD. In this chapter, we will discuss our current knowledge...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Sunil K Verma Muge N Kuyumcu-Martinez Source Type: research

RNA binding proteins in cardiovascular development and disease
Curr Top Dev Biol. 2024;156:51-119. doi: 10.1016/bs.ctdb.2024.01.007. Epub 2024 Mar 15.ABSTRACTCongenital heart disease (CHD) is the most common birth defect affecting>1.35 million newborn babies worldwide. CHD can lead to prenatal, neonatal, postnatal lethality or life-long cardiac complications. RNA binding protein (RBP) mutations or variants are emerging as contributors to CHDs. RBPs are wizards of gene regulation and are major contributors to mRNA and protein landscape. However, not much is known about RBPs in the developing heart and their contributions to CHD. In this chapter, we will discuss our current knowledge...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Sunil K Verma Muge N Kuyumcu-Martinez Source Type: research

RNA binding proteins in cardiovascular development and disease
Curr Top Dev Biol. 2024;156:51-119. doi: 10.1016/bs.ctdb.2024.01.007. Epub 2024 Mar 15.ABSTRACTCongenital heart disease (CHD) is the most common birth defect affecting>1.35 million newborn babies worldwide. CHD can lead to prenatal, neonatal, postnatal lethality or life-long cardiac complications. RNA binding protein (RBP) mutations or variants are emerging as contributors to CHDs. RBPs are wizards of gene regulation and are major contributors to mRNA and protein landscape. However, not much is known about RBPs in the developing heart and their contributions to CHD. In this chapter, we will discuss our current knowledge...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Sunil K Verma Muge N Kuyumcu-Martinez Source Type: research

RNA binding proteins in cardiovascular development and disease
Curr Top Dev Biol. 2024;156:51-119. doi: 10.1016/bs.ctdb.2024.01.007. Epub 2024 Mar 15.ABSTRACTCongenital heart disease (CHD) is the most common birth defect affecting>1.35 million newborn babies worldwide. CHD can lead to prenatal, neonatal, postnatal lethality or life-long cardiac complications. RNA binding protein (RBP) mutations or variants are emerging as contributors to CHDs. RBPs are wizards of gene regulation and are major contributors to mRNA and protein landscape. However, not much is known about RBPs in the developing heart and their contributions to CHD. In this chapter, we will discuss our current knowledge...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Sunil K Verma Muge N Kuyumcu-Martinez Source Type: research

Construction of recombinant pseudorabies virus expressing PCV2 Cap, PCV3 Cap, and IL-4: investigation of their biological characteristics and immunogenicity
ConclusionrPRV-2Cap/3Cap and rPRV-2Cap/3Cap/IL4 hold promise as recombinant vaccines for the simultaneous prevention of PCV2, PCV3, and PRV, while IL-4, as a vaccine molecular adjuvant, effectively enhances the immune response of the vaccine. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - March 20, 2024 Category: Allergy & Immunology Source Type: research

Perfusion techniques for an 800  g premature neonate undergoing Arterial Switch Procedure for Transposition of the Great Arteries★
We report perfusion techniques successfully utilized during the surgical repair of transposition of the great arteries for an 800 g, 28-week-old neonate. CPB techniques for the smallest and youngest patients may be executed safely when proper physical, chemical, and perfusion process adjustments are made and managed meticulously.PMID:38488714 | DOI:10.1051/ject/2023045 (Source: Journal of Extra-Corporeal Technology)
Source: Journal of Extra-Corporeal Technology - March 15, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Richard Owens Madeline Loftin Kellen Rosten Douglas Fisher Blake Denison Erin Gottlieb Charles Fraser Source Type: research

Perfusion techniques for an 800  g premature neonate undergoing Arterial Switch Procedure for Transposition of the Great Arteries★
We report perfusion techniques successfully utilized during the surgical repair of transposition of the great arteries for an 800 g, 28-week-old neonate. CPB techniques for the smallest and youngest patients may be executed safely when proper physical, chemical, and perfusion process adjustments are made and managed meticulously.PMID:38488714 | PMC:PMC10941837 | DOI:10.1051/ject/2023045 (Source: Journal of Extra-Corporeal Technology)
Source: Journal of Extra-Corporeal Technology - March 15, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Richard Owens Madeline Loftin Kellen Rosten Douglas Fisher Blake Denison Erin Gottlieb Charles Fraser Source Type: research