Archives of Disease in Childhood - Fetal and Neonatal Edition This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Effects of prophylactic hydrocortisone in a tertiary Canadian NICU
Bronchopulmonary dysplasia (BPD) is a common complication of preterm birth. Recent evidence suggests that the use of physiological doses of hydrocortisone for the prevention of death or BPD may outweigh the potential risks.1–3 Starting in 2019, all infants born <28 weeks gestational age (GA) in our tertiary care NICU received physiologic doses of hydrocortisone, starting within 24 hours post-birth. Our objective was to determine the effect of prophylactic hydrocortisone on the incidence of survival without moderate or severe BPD; secondary objectives assessed duration of respiratory support and safety outcomes. We...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: de Souza, M., Melika, R., Thebaud, B., Barrowman, N. J., Tsampalieros, A., Lemyre, B. Tags: PostScript Source Type: research

Treatment courses and outcomes of oesophageal atresia in patients with trisomy 18: a case series of 271 patients from a nationwide database in Japan
Conclusion This study provides information that will aid the clinical decision-making process for patients with oesophageal atresia and trisomy 18. Radical surgery may be a safe and feasible treatment option. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: Kutsukake, M., Konishi, T., Fujiogi, M., Takamoto, N., Morita, K., Yasuhisa, I., Hashimoto, Y., Matsui, H., Fushimi, K., Fujishiro, J., Yasunaga, H. Tags: Original research Source Type: research

Bronchopulmonary dysplasia: temporal trend from 2010 to 2019 in the Brazilian Network on Neonatal Research
Conclusion The frequency of BPD in survivors was constant and BPD or death decreased by 1.05% at each study year. These results show some improvement in perinatal care in Brazilian units which resulted in a reduction of BPD or death, but further improvements are still needed to reduce BPD in survivors. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: Stolz, C., Costa-Nobre, D. T., Sanudo, A., Ferreira, D. M. d. L. M., Sales Alves, J. M., dos Santos, J. P., Miyoshi, M. H., Silva, N. M. d. M., Melo, F. P. d. G., da Silva, R. V. C., Barcala, D., Vale, M. S., de Souza Rugolo, L. M. S., Diniz, E. M. A., Ri Tags: Original research Source Type: research

Effect of body position on ventilation distribution in healthy newborn infants: an observational study
Conclusions Prone or lateral body positioning in healthy spontaneously breathing newborns leads to a redistribution of ventilation to the non-dependent lung regions and at the same time global tidal volume is reduced as compared with supine. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: Rahtu, M., Frerichs, I., Pokka, T., Becher, T., Peltoniemi, O., Kallio, M. Tags: Original research Source Type: research

Polyethylene bags before cord clamping in very preterm infants: a randomised controlled trial
Conclusions Placing a PB before CC did not increase the proportion of preterm infants with normal temperature on NICU admission. A large proportion of preterm infants had abnormal temperature. Further studies on thermoregulation before CC are needed. Trial registration number NCT04463511 (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: Dunne, E. A., Ni Chathasaigh, C. M., Geraghty, L. E., O'Donnell, C. P., McCarthy, L. K. Tags: Open access Original research Source Type: research

Evolution of the Sarnat exam and association with 2-year outcomes in infants with moderate or severe hypoxic-ischaemic encephalopathy: a secondary analysis of the HEAL Trial
Conclusion Both rSE and change between qSE and rSE were strongly associated with the odds of death/NDI at 22–36 months in infants with moderate or severe HIE. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: Mietzsch, U., Kolnik, S. E., Wood, T. R., Natarajan, N., Gonzalez, F. F., Glass, H., Mayock, D. E., Bonifacio, S. L., Van Meurs, K., Comstock, B. A., Heagerty, P. J., Wu, T.-W., Wu, Y. W., Juul, S. E., on behalf of the HEAL Trial Study Group Tags: Original research Source Type: research

Late surfactant administration after 48 hours of age in preterm neonates with respiratory insufficiency: a systematic review and meta-analysis
Conclusions Administration of late surfactant does not improve the rates of death or BPD at 36 weeks when administered to preterm infants with prolonged respiratory insufficiency. Additional adequately powered trials are needed to establish the efficacy of late surfactant therapy in preterm infants. PROSPERO registration number CRD42023432463. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: Solis-Garcia, G., Elias, S., Dunn, M., Jasani, B. Tags: Original research Source Type: research

Maternal treatment with selective serotonin reuptake inhibitors during pregnancy and delayed neonatal adaptation: a population-based cohort study
Conclusions Infants exposed to SSRIs have increased risks of delayed adaptation in a type and dose-dependent relationship, pointing toward a causal relationship. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: Cornet, M.-C., Wu, Y. W., Forquer, H., Avalos, L. A., Sriram, A., Scheffler, A. W., Newman, T. B., Kuzniewicz, M. W. Tags: Open access Original research Source Type: research

Impact of cord clamping on haemodynamic transition in term newborn infants
Conclusions This study illustrates the cardiovascular consequences of CC in term vigorous infants and offers insight into the haemodynamic transition from fetal to neonatal circulation in spontaneously breathing newborns. Strategies that aim to enhance left ventricular preload before CC may prevent complications of perinatal cardiovascular imbalance. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: Chioma, R., Finn, D., Healy, D. B., Herlihy, I., Livingstone, V., Panaviene, J., Dempsey, E. M. Tags: Open access Original research Source Type: research

Characteristics and outcomes of neonates hospitalised with SARS-CoV-2 infection in the UK by variant: a prospective national cohort study
Conclusions Inpatient care for neonates with SARS-CoV-2 was uncommon. Although rare, severe neonatal illness was more common during the delta variant period, potentially reflecting more severe maternal disease and associated preterm birth. Trial registration number ISRCTN60033461. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: Gale, C., Sharkey, D., Fitzpatrick, K. E., Mactier, H., Morelli, A., Nakahara, M., Hurd, M., Placzek, A., Knight, M., Ladhani, S. N., Draper, E. S., Doherty, C., Quigley, M. A., Kurinczuk, J. J., Neonatal complications of COVID-19 Collaborative Group Tags: Open access, COVID-19 Original research Source Type: research

Neurodevelopmental outcome at 5.5 years in Dutch preterm infants born at 24-26 weeks gestational age: the EPI-DAF study
Conclusions After lowering the threshold for supporting active treatment from 25 to 24 completed weeks’ gestation, a considerable proportion of the surviving extremely preterm children did not have any impairment at 5.5 years’ CA. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: van Beek, P. E., Rijken, M., Broeders, L., ter Horst, H. J., Koopman-Esseboom, C., de Kort, E., Laarman, A. R. C., Mulder - de Tollenaer, S. M., Steiner, K., Swarte, R. M. C., van Westering-Kroon, E., Oei, G., Leemhuis, A. G., Andriessen, P. Tags: Open access Original research Source Type: research

Paediatric intensive care admissions of preterm children born
Conclusions Most babies born <32 weeks and discharged home from neonatal care do not require PICU admission in the first 2 years. The odds of unplanned admissions to PICU were greater in the most preterm and those with significant neonatal morbidity. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: van Hasselt, T. J., Gale, C., Battersby, C., Davis, P. J., Draper, E., Seaton, S. E., On behalf of the United Kingdom Neonatal Collaborative and the Paediatric Critical Care Society Study Group (PCCS-SG) Tags: Open access Original research Source Type: research

Current management of neonatal abstinence syndrome: a survey of practice in the UK and Ireland
Conclusion and relevance Compared with the previous survey, improvements in evidence-based practices were noted, highlighting the benefits of this type of research. Nonetheless, significant variation still exists in some aspects of the management of NAS. Post-discharge follow-up varies widely, with particular deficits in ophthalmology follow-up. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: Dempsey, S., O Grady, M. J. Tags: Original research Source Type: research

Parenting stress and health-related quality of life among parents of extremely preterm born early adolescents in England: a cross-sectional study
Conclusions In early adolescence, compared with parents of term-born children, EP parents experience increased levels of parenting stress that are particularly high among a proportion of parents and associated with lower mental health-related quality of life. Practitioner awareness of this continuing risk throughout childhood is important to support parental abilities and well-being. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: Suonpera, E., Lanceley, A., Ni, Y., Marlow, N. Tags: Open access Original research Source Type: research

Diagnosis and management of congenital diaphragmatic hernia: a 2023 update from the Canadian Congenital Diaphragmatic Hernia Collaborative
Conclusions The 2023 Canadian CDH Collaborative’s clinical practice guideline update provides a management framework for infants and children with CDH based on the best available evidence and expert consensus. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: Puligandla, P., Skarsgard, E., Baird, R., Guadagno, E., Dimmer, A., Ganescu, O., Abbasi, N., Altit, G., Brindle, M., Fernandes, S., Dakshinamurti, S., Flageole, H., Hebert, A., Keijzer, R., Offringa, M., Patel, D., Ryan, G., Traynor, M., Zani, A., Chiu, P Tags: Editor's choice Original research Source Type: research