Fluorescence-guided resection of intradural spinal tumors: a systematic review and meta-analysis
AbstractIntradural spinal tumors present significant challenges due to involvement of critical motor and sensory tracts. Achieving maximal resection while preserving functional tissue is therefore crucial. Fluorescence-guided surgery aims to improve resection accuracy and is well studied for brain tumors, but its efficacy has not been fully assessed for spinal tumors. This meta-analysis aims to delineate the efficacy of fluorescence guidance in intradural  spinal tumor resection. The authors performed a systematic review in four databases. We included studies that have utilized fluorescence agents, 5-aminolevulinic acid (...
Source: Neurosurgical Review - December 12, 2023 Category: Neurosurgery Source Type: research

Imaging of supratentorial intraventricular masses in children: a pictorial review —part 2
ConclusionThe WHO CNS5 introduces notable changes, emphasizing the vital importance of molecular diagnostics in classifying pediatric central nervous system tumors. These foundational shifts have significant potential to impact management strategies and, as a result, the outcomes of intraventricular masses in children. (Source: Neuroradiology)
Source: Neuroradiology - December 12, 2023 Category: Radiology Source Type: research

Spinal Cord Tumors: A Review of Demographic Characteristics and Treatment Follow-Up of Patients in Isfahan City, Iran
CONCLUSION: The results may contribute to improve the pre-operative planning, optimization, and monitoring of the patient's recovery after the operation.PMID:38073727 | PMC:PMC10699237 | DOI:10.4103/abr.abr_168_23 (Source: Adv Data)
Source: Adv Data - December 11, 2023 Category: Epidemiology Authors: Mehdi Mahmoodkhani Majid Rezvani Majid Aliyari Mehdi Shafiei Donya S Tehrani Source Type: research

A new subtype of diffuse midline glioma, H3 K27 and BRAF/FGFR1 co-altered: a clinico-radiological and histomolecular characterisation
In conclusion,DMG, H3 K27 and BRAF/FGFR1 co-altered represent a new subtype of DMG with distinct genotype/phenotype characteristics, which deserve further attention with respect to trial interpretation and patient management. (Source: Acta Neuropathologica)
Source: Acta Neuropathologica - December 8, 2023 Category: Neurology Source Type: research

5-aminolevulinic acid-guided endoscopic biopsy with violet light-emitting diode flashlight in malignant glioma: Technical note
CONCLUSION: This technique of neuroendoscopic biopsy guided by 5-ALA PDD fluorescence with a violet LED flashlight may allow a safe and accurate diagnosis of deep-seated malignant gliomas.PMID:38053712 | PMC:PMC10695459 | DOI:10.25259/SNI_204_2023 (Source: Surgical Neurology International)
Source: Surgical Neurology International - December 6, 2023 Category: Neurosurgery Authors: Michiharu Yoshida Susumu Yamaguchi Keisuke Iwasaki Mitsuto Iwanaga Source Type: research