The diagnostic challenge of lack of choline level elevation on 1H-MR spectroscopy in grade II-III gliomas
Folia Neuropathol. 2024;62(1):13-20. doi: 10.5114/fn.2024.136469.ABSTRACTThe accurate diagnosis of brain tumour is very important in modern neuro-oncology medicine. Magnetic resonance spectroscopy (MRS) is supposed to be a promising tool for detecting cancerous lesions. However, the interpretation of MRS data is complicated by the fact that not all cancerous lesions exhibit elevated choline (Cho) levels. The main goal of our study was to investigate the lack of Cho lesion /Cho ref elevation in the population of grade II-III gliomas. 89 cases of gliomas grade II and III were used for the retrospective analysis - glioma (ast...
Source: Folia Neuropathologica - May 14, 2024 Category: Pathology Authors: Barbara Bobek-Billewicz Sylwia Heinze Krzysztof Majchrzak Patrycja Mazgaj Anna Hebda Source Type: research

The diagnostic challenge of lack of choline level elevation on 1H-MR spectroscopy in grade II-III gliomas
Folia Neuropathol. 2024;62(1):13-20. doi: 10.5114/fn.2024.136469.ABSTRACTThe accurate diagnosis of brain tumour is very important in modern neuro-oncology medicine. Magnetic resonance spectroscopy (MRS) is supposed to be a promising tool for detecting cancerous lesions. However, the interpretation of MRS data is complicated by the fact that not all cancerous lesions exhibit elevated choline (Cho) levels. The main goal of our study was to investigate the lack of Cho lesion /Cho ref elevation in the population of grade II-III gliomas. 89 cases of gliomas grade II and III were used for the retrospective analysis - glioma (ast...
Source: Folia Neuropathologica - May 14, 2024 Category: Neurology Authors: Barbara Bobek-Billewicz Sylwia Heinze Krzysztof Majchrzak Patrycja Mazgaj Anna Hebda Source Type: research

The diagnostic challenge of lack of choline level elevation on 1H-MR spectroscopy in grade II-III gliomas
Folia Neuropathol. 2024;62(1):13-20. doi: 10.5114/fn.2024.136469.ABSTRACTThe accurate diagnosis of brain tumour is very important in modern neuro-oncology medicine. Magnetic resonance spectroscopy (MRS) is supposed to be a promising tool for detecting cancerous lesions. However, the interpretation of MRS data is complicated by the fact that not all cancerous lesions exhibit elevated choline (Cho) levels. The main goal of our study was to investigate the lack of Cho lesion /Cho ref elevation in the population of grade II-III gliomas. 89 cases of gliomas grade II and III were used for the retrospective analysis - glioma (ast...
Source: Folia Neuropathologica - May 14, 2024 Category: Pathology Authors: Barbara Bobek-Billewicz Sylwia Heinze Krzysztof Majchrzak Patrycja Mazgaj Anna Hebda Source Type: research

The diagnostic challenge of lack of choline level elevation on 1H-MR spectroscopy in grade II-III gliomas
Folia Neuropathol. 2024;62(1):13-20. doi: 10.5114/fn.2024.136469.ABSTRACTThe accurate diagnosis of brain tumour is very important in modern neuro-oncology medicine. Magnetic resonance spectroscopy (MRS) is supposed to be a promising tool for detecting cancerous lesions. However, the interpretation of MRS data is complicated by the fact that not all cancerous lesions exhibit elevated choline (Cho) levels. The main goal of our study was to investigate the lack of Cho lesion /Cho ref elevation in the population of grade II-III gliomas. 89 cases of gliomas grade II and III were used for the retrospective analysis - glioma (ast...
Source: Folia Neuropathologica - May 14, 2024 Category: Neurology Authors: Barbara Bobek-Billewicz Sylwia Heinze Krzysztof Majchrzak Patrycja Mazgaj Anna Hebda Source Type: research

The diagnostic challenge of lack of choline level elevation on 1H-MR spectroscopy in grade II-III gliomas
Folia Neuropathol. 2024;62(1):13-20. doi: 10.5114/fn.2024.136469.ABSTRACTThe accurate diagnosis of brain tumour is very important in modern neuro-oncology medicine. Magnetic resonance spectroscopy (MRS) is supposed to be a promising tool for detecting cancerous lesions. However, the interpretation of MRS data is complicated by the fact that not all cancerous lesions exhibit elevated choline (Cho) levels. The main goal of our study was to investigate the lack of Cho lesion /Cho ref elevation in the population of grade II-III gliomas. 89 cases of gliomas grade II and III were used for the retrospective analysis - glioma (ast...
Source: Folia Neuropathologica - May 14, 2024 Category: Pathology Authors: Barbara Bobek-Billewicz Sylwia Heinze Krzysztof Majchrzak Patrycja Mazgaj Anna Hebda Source Type: research

The diagnostic challenge of lack of choline level elevation on 1H-MR spectroscopy in grade II-III gliomas
Folia Neuropathol. 2024;62(1):13-20. doi: 10.5114/fn.2024.136469.ABSTRACTThe accurate diagnosis of brain tumour is very important in modern neuro-oncology medicine. Magnetic resonance spectroscopy (MRS) is supposed to be a promising tool for detecting cancerous lesions. However, the interpretation of MRS data is complicated by the fact that not all cancerous lesions exhibit elevated choline (Cho) levels. The main goal of our study was to investigate the lack of Cho lesion /Cho ref elevation in the population of grade II-III gliomas. 89 cases of gliomas grade II and III were used for the retrospective analysis - glioma (ast...
Source: Folia Neuropathologica - May 14, 2024 Category: Neurology Authors: Barbara Bobek-Billewicz Sylwia Heinze Krzysztof Majchrzak Patrycja Mazgaj Anna Hebda Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research