Risk Factors for the Development of Postoperative Acute Kidney Injury in Patients Undergoing Joint Replacement Surgery: A Meta-Analysis.
Abstract A new-onset acute kidney injury (AKI) after arthroplasty impairs rehabilitation and outcome. A prior knowledge of risk factors contributes to a planned preventive management and prognostication. Although many studies have addressed the issue, our objective was to perform a meta-analysis to bring a consensus on the perioperative risk factors promoting AKI postoperatively. We conducted a systematic review and meta-analysis of observational studies reporting risk factors with odds of development of AKI according to the existing criteria after hip or knee replacement surgery. We searched the PubMed and Google...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Rao PB, Singh N, Tripathy SK Tags: Saudi J Kidney Dis Transpl Source Type: research

Birth Weight and Susceptibility to Chronic Kidney Disease.
This article aims at discussing LBW and the susceptibility to CKD. Furthermore, in postnatal environment, the weight gain or change at adult life increases the metabolic demand and determines the phenotypic expression of disease along with the spectrum of nephron number. Hence, a cycle of hyperfiltration mechanism of these nephrons leads to proteinuria, glomerulo- sclerosis, and progressive development of larger glomeruli, a greater risk of proteinuria and progressive CKD. Therefore, LBW offspring are at risk of developing CKD (defined as albuminuria, a reduced glomerular filtration rate, or renal failure) in later life. F...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Al Salmi I, Hannawi S Tags: Saudi J Kidney Dis Transpl Source Type: research

Angiotensin-Converting Enzyme Inhibitor Captopril: Does it Improve Renal Function in Lipopolysaccharide-induced Inflammation Model in Rats.
Abstract Renin-angiotensin system as an important regulator of renal function has also a major role in inflammation. In the present study, the effects of captopril on renal dysfunction, renal cytokine levels, and renal tissue oxidative damage were investigated in lipopolysaccharide (LPS)-induced inflammation model in rats. Treatment of five groups of the rats was carried out as follows: (1) saline as a control, (2) LPS 1 mg/kg, and (3-5) 10, 50, or 100 mg/kg captopril 30 min, respectively, before LPS. The treatments were given for 12 days. Finally, the animals were deeply anesthetized, the blood samples were obtai...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Azizi-Malekabadi H, Beheshti F, Abareshi A, Norouzi F, Khazaei M, Soukhtanloo M, Hosseini M Tags: Saudi J Kidney Dis Transpl Source Type: research

Survey of Patient's Experience of Altruistic Nondirected Kidney Donation.
Abstract The scarcity of organs for donation is an ongoing issue. Change in legislative framework allows for altruistic donations in the UK, but, whereas the number of donations from deceased donors has increased, there has been a slow decline in altruistic living donors. The aim of this study was to review perspectives of altruistic nondirected kidney donors (ANDKD) at our center and outcome of all enquiries to inform service improvement and increase the numbers of donors. All enquiries by potential ANDKD at our center from September 2005 to September 2017 were analyzed. Donor assessment was performed as per the ...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Schumacher KJ, Stacey S, Akoh JA Tags: Saudi J Kidney Dis Transpl Source Type: research

Echocardiographic Evaluation of Left Atrial Volume Index in Patients with Chronic Kidney Disease.
Abstract Chronic kidney disease (CKD) patients are at high risk of developing cardio vascular disease. Left atrial volume index (LAVi) is an indicator of left ventricular diastolic dysfunction. We conducted this study to find out the correlation of LAVi and other echocardio- graphic parameters with estimated glomerular filtration rate (eGFR). We prospectively enrolled 170 individuals: 69 patients with CKD and 101 controls. Echocardiographic parameters including systolic and diastolic volumes of left ventricle, LAVi, ejection fraction (EF), pulmonary artery systolic pressure (PASP), and E/e ratio were measured in a...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Bokhari SR, Mansur A, Khan Assir MZ, Ittifaq A, Sarwar S Tags: Saudi J Kidney Dis Transpl Source Type: research

Influenza A (H1N1) Virus Infection Associated Acute Kidney Injury - A Study from a Tertiary Care Center in South India.
Abstract Influenza A (H1N1) infection in 2009 spread rapidly all over the world. Mortality was high in patients with H1N1-associated acute kidney injury (AKI). We estimated the incidence, risk factors of AKI and mortality associated with H1N1 infection. This is a prospective observational study, including 158 adult patients with H1N1 infection confirmed with real-time reverse transcriptase-polymerase chain reaction conducted between August 2016 and September 2017. AKIN criteria were used to define AKI. Of 158 patients in this study, 112 were male and the mean age was 46.4. Fifteen patients (9.5%) were found to hav...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Indhumathi E, Krishna Makkena V, Mamidi V, Jayaprakash V, Jayakumar M Tags: Saudi J Kidney Dis Transpl Source Type: research

The Prevalence of Frailty and its Association with Cognitive Dysfunction among Elderly Patients on Maintenance Hemodialysis: A Cross-Sectional Study from South India.
Abstract Data are scarce regarding the prevalence of frailty in elderly patients undergoing maintenance hemodialysis (HD) in India. We conducted a cross-sectional observational study aimed to study the prevalence of frailty and cognitive dysfunction in patients aged 75 years or more undergoing maintenance HD in three tertiary care hospitals and associated stand-alone dialysis centers in North Kerala. Frailty was ascertained by two methods. In method 1 (physical performance measurement based), dichotomous scoring (0 or 1) of five domains, namely weight loss, exhaustion, low physical activity, weak grip, and slow wa...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Gopinathan JC, Hafeeq B, Aziz F, Narayanan S, Aboobacker IN, Uvais NA Tags: Saudi J Kidney Dis Transpl Source Type: research

The Effect of Nigella Sativa on Renal Oxidative Injury in Diabetic Rats.
Abstract Oxidative stress plays a key role in the evolution of diabetes complications. The current study looked into the potential effects of the hydroalcoholic extract of Nigella sativa on the oxidative injury of the rat kidneys in diabetic animals. The animals were placed into five study groups in a random manner as follows: (1) control, (2) diabetic, (3 and 4) treatment with two doses of N. sativa extract (200 and 400 mg/kg), and (5) treatment with metformin (300 mg/kg). The time course of administration was six weeks. The malondialdehyde (MD A) and total thiol groups, as well as the superoxide dismutase and ca...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Mohebbati R, Abbasnezhad A, Havakhah S, Mousavi M Tags: Saudi J Kidney Dis Transpl Source Type: research

Heat Shock Protein 70 Gene Polymorphism in Egyptian Patients with Type 2 Diabetes Mellitus, with and without Nephropathy.
This study was carried out on 90 patients divided into three groups: 30 patients of Type 2 DM with nephropathy (Group I), 30 patients of Type 2 DM without nephropathy (Group II) with duration of diabetes> 10 years in both patient groups, and 30 healthy persons, who served as controls (Group III). All the studied patients were submitted to full history taking, complete clinical examination, and laboratory investigations including fasting blood glucose, glycated hemoglobin, renal function tests, and urinary albumin- to-creatinine ratio. HSP70-1 -110 AC, +190 G/C, HSP70-2 +1267 A/G, and shock protein70- hom +2437 T/C gene ...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Elshahed OM, Shaker OG Tags: Saudi J Kidney Dis Transpl Source Type: research

Cognitive Dysfunction in Patients with Chronic Kidney Disease.
This study was performed to evaluate cognitive dysfunction and its severity in different stages of CKD and identify the correlation with factors affecting this dysfunction. A cross-sectional design study was conducted on 100 patients with CKD Stage III to V-D fulfilling the eligibility criteria. Cognitive status was assessed using the mini-mental state examination (MMSE) and Montreal cognitive assessment (MoCA) tests. The patients were divided into four groups according to their estimated glomerular filtration rate (eGFR); Group A with eGFR ranging between 30 and 59 mL/min/1.73 m2, Group B with eGFR between 15 and 29 mL/mi...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Aggarwal HK, Jain D, Bhavikatti A Tags: Saudi J Kidney Dis Transpl Source Type: research

Chest Ultrasound as a New Tool for Assessment of Volume Status in Hemodialysis Patients.
Abstract Accurate assessment of volume status (VS) in hemodialysis (HD) patients is challenging. The use of chest ultrasound (CUS) for detection of extravascular lung water has recently gained wide acceptance. The aim of this study was to evaluate the use of CUS in VS assessment in HD patients in comparison to clinical and inferior vena cava (IVC) indices and to assess their relation with volume displacement after ultrafiltration. This prospective cohort study was carried out on 38 patients on regular HD. VS was assessed using a 13-point clinical score, and IVC indices and CUS score were measured pre- and post-ult...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Mohammad WH, Elden AB, Abdelghany MF Tags: Saudi J Kidney Dis Transpl Source Type: research

Arterial Hypertension in Systemic Lupus Erythematosus: About 40 Cases.
Abstract The aim of this study was to determine the prevalence and the etiologic profile of hypertension (HTN) in systemic lupus erythematosus (SLE). A retrospective analysis was performed on 153 patients with SLE who attended our center for 16 years from January 2000 to December 2016. The diagnosis of SLE was established according to the classification criteria of the American College of Rheumatology in 1990. The prevalence of HTN in patients with SLE was 26.1% (40/153)' with an average delay of appearance of 21 months. There were 37 women and three men with a mean age of 46' eight years (20-70). HTN was associat...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Rachdi I, Daoud F, Zoubeidi H, Somai M, Fekih Y, Dhaou BB, Aydi Z, Boussema F Tags: Saudi J Kidney Dis Transpl Source Type: research

Attitudes, Knowledge, and Social Perceptions toward Organ Donation and Transplantation in Eastern Morocco.
Abstract The study is aimed to assess attitudes, knowledge, and social perceptions toward organ donation and transplantation in Eastern Morocco and therefore understand what sets back this activity's expansion and progression. We conducted a cross-sectional study involving three groups of persons that are theoretically involved in the process of organ donation (medical students, law students, and nurses). Data were collected using an anonymous questionnaire related to the cultural, religious, medical, and legal aspects of organ donation and transplantation. Six hundred questionnaires were distributed. The particip...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Haddiya I, El Meghraoui H, Bentata Y, Guedira M Tags: Saudi J Kidney Dis Transpl Source Type: research

Renal Data from the Arab World Dialysis in Kuwait: 2013-2019.
Abstract The total number of end-stage kidney disease patients treated with dialysis in 2019 in Kuwait was 2230, with a 6% increase from the year before. Dialysis prevalence was 465 per million population (PMP) and dialysis incidence was100 PMP. Kuwaiti nationals represented 70% of the dialysis population and males represented 52%. Of the same population, 59% had diabetes. Hepatitis C virus affected
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: AlSahow A, AlHelal B, Alyousef A, AlQallaf A, Marzouq A, Nawar H, Fanous G, Abdelaty M, Bahbahani Y, AlRajab H, AlTerkait A, Ali H Tags: Saudi J Kidney Dis Transpl Source Type: research

Prevalence of Nondiabetic Renal Disease in Patients with Type 2 Diabetes Mellitus with Clinicopathological Correlation: A Study from a Tertiary Care Center of Assam, India.
This study aimed to evaluate the renal biopsies performed on type 2 diabetic patients for suspicion of NDRD and to correlate clinicopathological findings. All T2DM patients aged> 18 years were included in this study, who had renal biopsy performed for the following reasons: recent-onset nephrotic syndrome, unexplained rapid deterioration of renal function, proteinuria not accompanied by retinopathy, and unexplained hematuria. Renal biopsy was analyzed by light microscopy and immunofluorescence. Based on biopsy findings, the patients were grouped into three: (i) isolated NDRD, (ii) NDRD ± diabetic nephropathy (DN)...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Sharma M, Parry MA, Jeelani H, Mahanta PJ, Doley PK, Pegu G Tags: Saudi J Kidney Dis Transpl Source Type: research

Hemodialysis at Doorstep - "Hub-and-Spoke" Model of Dialysis in a Developing Country.
This study highlights the important features of this model. PMID: 32801246 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Sahay M, Ismal K, Vali PS Tags: Saudi J Kidney Dis Transpl Source Type: research

Biopsy-proven Renal Pathologies: Experience from Multan Institute of Kidney Diseases.
This study sets alight to explore membranous nephropathy, which is the leading primary glomerular disease in our studied population. PMID: 32801247 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Hashmi MN, Asghar R, Abbasi T, Bashir K, Basharat R, Majeed S Tags: Saudi J Kidney Dis Transpl Source Type: research

Granulomatous Interstitial Nephritis Due to Renal-limited Sarcoidosis.
We report a case of a 42-year-old man with a history of unexplained weight loss admitted with progressively worsening kidney function. Physical examination did not show any abnormality. Laboratory investigations were normal except for high calcium level with no evidence of organ involvement of sarcoidosis. A renal biopsy showed GIN with non-caseating granulomata. Prednisolone was initiated and renal function improved. This is a case of an extremely rare AKI caused by sarcoid GIN without extra-renal manifestations which responded to prednisolone. PMID: 32801248 [PubMed - as supplied by publisher] (Source: Saudi Journal...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Alangari FS, Binsalih SA, Heijani B, Aloudah N Tags: Saudi J Kidney Dis Transpl Source Type: research

Primary Anti-phospholipid Antibody Syndrome Presenting as Acute Nephritic Syndrome.
We report here a case of a 22-year-old man who presented with acute nephritic syndrome following an acute febrile illness. He was detected to have altered renal function tests with serum creatinine of 1.6 mg/dL (141.4 μmol/L), microscopic hematuria, and proteinuria along with hypertension. His 24-h urine protein was 1700 g/day. He was planned for a kidney biopsy. Subsequent evaluations revealed an isolated elevation of activated partial thromboplastin time. Further evaluation revealed positive APLA syndrome. He underwent kidney biopsy later which showed mesangial hypercellularity with no involvement of the renal parench...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Upendran B, Kumar VR, Thomas P Tags: Saudi J Kidney Dis Transpl Source Type: research

Epstein Syndrome.
Abstract Epstein syndrome is characterized by sensorineural hearing impairment, macro- thrombocytopenia without neutrophil inclusion bodies, and hereditary nephritis which can progress to end-stage renal disease (ESRD) in adolescence. The prognosis of Epstein's syndrome depends on the severity of the hematological disorders and renal involvement that can lead to ESRD at an early age. Thrombocytopenia in Epstein syndrome is not an absolute contraindication for major surgical procedures like arteriovenous fistula formation or kidney transplantation. There are no set guidelines for preoperative prophylaxis in a patie...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Barrah S, Kheder R, Jebali H, Krid M, Smaoui W, Beji S, Hmida FB, Fatma LB, Rais L, Zouaghi MK Tags: Saudi J Kidney Dis Transpl Source Type: research

Disseminated Histoplasmosis Masquerading as Significant Weight Loss Eight Years Post Renal Transplant.
We describe a case with significant weight loss who got admitted for the evaluation for post-transplant lympho- proliferative disorder. The 30-year-old male patient presented with weight loss eight years post- renal transplant and detailed evaluation revealed systemic fungal infection involving cutaneous, pulmonary, and hematopoietic systems. PMID: 32801251 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Jha VK, Mahapatra D Tags: Saudi J Kidney Dis Transpl Source Type: research

Pellagra Disease in a Hemodialysis Patient.
We report a case of pellagra in a hemodialysis (HD) patient with breast neoplasia, aged 68-years, female, on HD unit for seven years. Her original nephropathy was indeterminate. The patient was followed up for homozygous beta-thalassemia and breast neoplasia with hepatic metastases on chemotherapy. The body mass index of the patient was 18.5 kg/m2. Physical examination showed a thickening of the epidermis with a scaly surface, pigmented, and atrophied areas. We noted neuropsychiatric signs (apathy, irritability, anorexia, and depression) and digestive symptomatology (diarrhea). The laboratory tests revealed hypoproteinemia...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Barrah S, Jebali H, Kheder R, Krid M, Smaoui W, Beji S, Hmida FB, Fatma LB, Rais L, Zouaghi MK Tags: Saudi J Kidney Dis Transpl Source Type: research

Rhabdomyolysis Induced Acute Kidney Injury in Acute Myeloid Leukemia: An Unusual Association.
Abstract Rhabdomyolysis is a potentially life-threatening syndrome that causes acute kidney injury. Association of acute myeloid leukemia (AML) and myoglobin induced acute tubular necrosis (ATN) is rarely reported in the literature. Here, we report a young male who was admitted with fever of unknown origin. Diagnosed to have AML with renal failure and subsequently succumbed to illness, whose post mortem renal biopsy confirmed myoglobin induced ATN. PMID: 32801253 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Chiniwalar A, Fernando ME, Sujit S, Srinivasa Prasad ND, Valavan KT Tags: Saudi J Kidney Dis Transpl Source Type: research

Neurocysticercosis and Adult-Onset Epilepsy.
PMID: 32801254 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2020 Category: Urology & Nephrology Authors: Rissardo JP, Fornari Caprara AL Tags: Saudi J Kidney Dis Transpl Source Type: research

ABO-incompatible transplantation without conventional induction immunosuppression (IL-2RB or depleting agents).
Abstract Transplantation across the ABO blood group (ABOI-Tx) has facilitated to increase in donor pool for living donor kidney transplantation. Increased risk of rejection despite augmented immunosuppression has been the concern for many transplant programs in initiating an ABOI-TX program. The benefits of induction immunosuppression on long-term graft survival in immunologically low-risk individuals are still not clear. Increased immunosuppression of ABOI-Tx recipients before transplantation could provide an opportunity to transplant without induction with IL2-R blockers or Lymphocyte depleting agents. The aim o...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Hafeeq B, Aziz F, Narayanan S, Aboobacker IN, Gopinathan JC, Narayanan R, Binu JJ, Uvais NA Tags: Saudi J Kidney Dis Transpl Source Type: research

Effect of Ramadan fasting on arterial stiffness parameters among Egyptian hypertensive patients with and without chronic kidney disease.
This study aims at evaluate of the effect of Ramadan fasting on AS parameters, augmentation index (AIx), and pulse wave velocity (PWV) in hypertensive patients with and without CKD. A cohort of 71 patients (mean age = 57.14 ± 14.5 years, 42 females and 29 males) were enrolled in this study; 34 with CKD and 37 without CKD. All patients had hypertension, while 25 patients had diabetes mellitus. Serum creatinine (Cr), serum urea, estimated glomerular filtration rate (eGFR) by CKD-EPI formula, brachial and central systolic blood pressure (BSP and CSP respectively), brachial and central diastolic blood pressure (BDP, CDP...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Eldeeb AA, Mahmoud MA, Ibrahim AB, Yousef EA, Sabry AA Tags: Saudi J Kidney Dis Transpl Source Type: research

Granulomatous interstitial nephritis in the military hospital of Morocco: Causes and outcomes.
Abstract Granulomatous interstitial nephritis (GIN) is a rare cause of renal failure. Most frequent etiologies are sarcoidosis, drugs, granulomatosis with polyangiitis, and infections agents (particularly renal tuberculosis). The aim of this retrospective study was to evaluate the clinical features, causes, and outcomes of patients with GIN in adult patients in a region of Morocco. All native renal biopsy (January 2008 to December 2017) were reviewed, but only cases of GIN were analyzed. Eleven cases of GIN were identified in this study, constituting 2.7 % of all native renal biopsies performed on this period (n =...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Zajjari Y, Azizi M, Bahadi A, Montasser D, Aatif T, Alayoud A, El Kabbaj D Tags: Saudi J Kidney Dis Transpl Source Type: research

Management of pain at arteriovenous fistula puncture: Cryotherapy versus lidocaine/prilocaine.
Abstract Pain at arteriovenous fistula (AVF) puncture is common in hemodialysis (HD) patients. The purpose of our work is to determine its frequency, to evaluate the efficiency of two techniques: anesthetic cream (Emla™) and cryotherapy, and to compare their efficiency. A prospective and interventional analytical study of HD patients was conducted in our structure. We included all patients with pain at AVF puncture. We evaluated the pain intensity using a visual analogue scale before and after our intervention: Emla™ cream during three consecutive HD sessions, then cryotherapy (ice cubes placed in late...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Kortobi L, Belymam H, Chkairi NM, Zamd M, Medkouri G, Gharbi MB, Ramdani B, El Khayat SS Tags: Saudi J Kidney Dis Transpl Source Type: research

Effects of dietary counseling on sodium restriction in patients with chronic kidney disease on hemodialysis: A randomized clinical trial.
This study was aimed to evaluate the effects of dietary counseling on sodium restriction and its relationship with clinical, dietary, and quality of life parameters in patients on HD treatment. This study was designed as a randomized clinical trial. The study included 87 patients on HD, divided into intervention (n = 47) and control (n = 40) groups. Anthropometric, clinical, sodium intake, and quality of life data were evaluated in both groups at four-time points: baseline (T0), 90 days (T3), 180 days (T6), and 365 days (T12). The intervention group received dietary counseling at the beginning and throughout the study. The...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: de Freitas AB, Nicoletto BB, Machado d'Almeida KS, Romano de Medeiros Bastos NM, Manfro RC, Souza GC Tags: Saudi J Kidney Dis Transpl Source Type: research

A multicenter study of malnutrition status in chronic kidney disease stages I-V-D from different socioeconomic groups.
Abstract There is a paucity of data on malnutrition in different socioeconomic status in chronic kidney disease (CKD) patients. Hence, this cross-sectional study was undertaken in CKD-ND and CKD-D. The aim of the study was to assess the prevalence of malnutrition in the various stages of CKD among the various socioeconomic groups, namely the low-income groups and the upper-middle-income groups. This is a cross-sectional study conducted among 394 patients. The patient data were obtained from three institutions: Institution 1, Institution 2, and Institution 3. Patients were predominantly from the South Indian popula...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Anupama SH, Abraham G, Alex M, Vijayan M, Subramanian KK, Fernando E, Nagarajan V, Nageshwara Rao PK Tags: Saudi J Kidney Dis Transpl Source Type: research

Barriers in knowledge and attitudes regarding organ donation among Urban Jordanian population.
This study aims to evaluate public attitudes and knowledge about deceased organ donation (DOD) in Jordan in support of larger efforts to increase donor rates. A mixed qualitative and quantitative approach was used. Qualitative, one-on-one interviews were used to create a quantitative survey, which was administered to randomly-selected individuals over a 5-month period. The questionnaire used series of statements to evaluate knowledge and attitude about DOD on a scaling system and converted to scores (0-4). A total of 15 qualitative interviews and 500 quantitative surveys (78.4% response rate) were completed. Only 78 (15.6%...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Abdulrazeq F, Matsumoto MM, Zourob M, Al-Dobai A, Zeyad K, Marwan N, Qeshta A, Aleyani O Tags: Saudi J Kidney Dis Transpl Source Type: research

Evaluation of electrocardiographic findings before and after hemodialysis session.
Abstract Dialysis patients have higher rates of sudden cardiac death. The study of the electrocardiogram could identify patients at risk of developing rhythm disorders. The aim of this study was to evaluate the electrocardiographic findings before and after the hemodialysis (HD) session and to examine associations of clinical and serum electrolytes with electrocardiogram findings. We conducted a multicentric transversal study, including chronic HD patients during January 2018. Standard 12-lead electrocardiogram was recorded, before and after the HD session. A medical history was documented. It included age, gender...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Jebali H, Ghabi H, Mami I, Fatma LB, Smaoui W, Kaab BB, Krid M, Hlima MB, Ayed TB, Guermazi O, Mourali MS, Beji S, Chermiti M, Zied L, Kateb H, Hassan M, Hmida FB, Raies L, Zouaghi MK Tags: Saudi J Kidney Dis Transpl Source Type: research

Seroprevalence of Hepatitis B, C and coinfection among patients with chronic kidney disease in a Nigerian hospital.
Abstract Infectious diseases remain a major health challenge in developing countries, compounding the woes of growing noncommunicable diseases such as chronic kidney disease (CKD). Increased morbidity and mortality have been reported among CKD patients with hepatitis infection and may necessitate protocol for treatment, follow-up, and prevention of spread. We aimed to determine the prevalence of viral hepatitis B and C infections among CKD patients and the effects on their liver enzymes. In this retrospective study, 314 CKD patients screened for hepatitis C virus (HCV) and hepatitis B surface antigen (HBsAg) were ...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Ogunleye A, Oluwafemi TT, Akinbodewa AA, Daomi VO, Adejumo OA, Omisakin TC Tags: Saudi J Kidney Dis Transpl Source Type: research

Consensus guidelines of cardiovascular risk assessment in kidney transplantation in Saudi Arabia: Review of current practice, evidence, and recommendations.
Abstract Screening for cardiovascular (CV) disease before transplant is common. However, the clinical utility of screening asymptomatic transplant candidates remains unclear. There is a large degree of variation among the practices of the different transplant centers in the Kingdom of Saudi Arabia (KSA) and among the international guidelines. Opinions are mostly based on mixed observational data with a great potential for bias. When compared to the Western countries, renal-transplant candidates in the KSA are likely to have longer dialysis vintage, higher prevalence of catheter use, higher rate of uncontrolled hyp...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Arabi Z, Theaby A, Sibai A, Bukhari MA, Al Chaghouri MS, Al-Mallah M, Ohali W, Abdullah K, Kheirallah H, Eid H, Rojolah H, Qaseer M, Hamawi K, Halim M Tags: Saudi J Kidney Dis Transpl Source Type: research

A rare cause of nephrotic syndrome.
Abstract Classical Alport syndrome is a rare X-linked disease of males (85%) presenting early with hematuria, ocular, and hearing defects. Proteinuria and renal failure are less common in the early stages. Here, we report the case of a young female with nephrotic range proteinuria, microscopic hematuria, and renal failure. A keen observation of abundant interstitial foam cells with suspicious glomerular basement membrane changes on kidney biopsy hinted the possibility of Alport syndrome. Further directed testing of the index patient and her family members including genetic analysis revealed a rare pathogenic varia...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Thomas RG, Senthilkumar RP, Velayudham B, Vasudevan C, Murugesan T Tags: Saudi J Kidney Dis Transpl Source Type: research

Collagenofibrotic glomerulopathy: A case of glomerular deposition disease in the Indian subcontinent and review of the literature.
Abstract Collagenofibrotic glomerulopathy (CG) is a rare renal disease with unknown etiology, defined by deposition of Type III collagen fibers in the subendothelial space and mesangium seen on supported by electron microscopy. There are merely 19 cases reported in the literature from the Indian subcontinent. Herein, we present a case report of CG from the Indian subcontinent and review its literature mainly focusing on histopathological findings. PMID: 32655054 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Modi SS, Balasubramaniam S, Sunilkumar K Tags: Saudi J Kidney Dis Transpl Source Type: research

Chylous nephrogenic ascites in a hemodialysis patient.
Abstract Chylous nephrogenic ascites is rare in hemodialysis (HD) patients. We would like to share a rare case of chylous nephrogenic ascites in a HD patient. The patient has a history of straw-colored nephrogenic ascites which was drained through pigtail five times in the past. Later on, the ascites became turbid and milky. The chloroform test of the ascitic fluid showed fat globules with Oil Red-O stain, and the triglyceride concentration of ascitic fluid was 168.14 mg/dL (1.93 mmol/L) satisfying the criteria of chylous ascites. We believe that this may be caused by microtrauma from repeated pigtail insertions f...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Mabood Khalil MA, Haji Jukmin MK, Chong VH, Tan J Tags: Saudi J Kidney Dis Transpl Source Type: research

Refusal rate for dialysis in a rural community in Indochina: What about the rate?
PMID: 32655056 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Sriwijitalai W, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Coronavirus-antibody immune complex: A nanostructure appraisal possible cause of nephropathology.
PMID: 32655057 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Sriwijitalai W, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Remarks about the published study on "Changes in body mass index after pediatric renal transplantation".
Remarks about the published study on "Changes in body mass index after pediatric renal transplantation". Saudi J Kidney Dis Transpl. 2020 May-Jun;31(3):696 Authors: Al-Mendalawi MD PMID: 32655058 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Al-Mendalawi MD Tags: Saudi J Kidney Dis Transpl Source Type: research

Author's reply.
PMID: 32655059 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Valavi E, Aminzadeh M Tags: Saudi J Kidney Dis Transpl Source Type: research

Risk-prediction model for COVID-19 infection in dialysis patients.
PMID: 32655060 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Yasri S, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Expected tuberculosis detection rate among the patients with chronic kidney disease: A report from endemic country of tuberculosis.
PMID: 32655061 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2020 Category: Urology & Nephrology Authors: Sookaromdee P, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Kidney health for everyone everywhere - from prevention to detection and equitable access to care.
Abstract The global burden of chronic kidney disease (CKD) is rapidly increasing with a projection of becoming the 5th most common cause of years of life lost globally by 2040. Aggravatingly, CKD is a major cause of catastrophic health expenditure. The costs of dialysis and transplantation consume up to 3% of the annual healthcare budget in high-income countries. Crucially, however, the onset and progression of CKD is often preventable. In 2020, the World Kidney Day campaign highlights the importance of preventive interventions - be it primary, secondary or tertiary. This complementing article focuses on outlining...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2020 Category: Urology & Nephrology Authors: Li PK, Garcia-Garcia G, Lui SF, Andreoli S, Fung WW, Hradsky A, Kumaraswami L, Liakopoulos V, Rakhimova Z, Saadi G, Strani L, Ulasi I, Kalantar-Zadeh K, World Kidney Day, Steering Committee Tags: Saudi J Kidney Dis Transpl Source Type: research

Proton-pump inhibitors and chronic kidney disease: Hidden consequences of an inappropriate drug use?
Abstract Proton-pump inhibitors (PPIs) are the most effective therapy for gastric acid- related diseases. They are generally well tolerated with rare, often self-limiting adverse reactions. On the other hand, there is growing concern regarding the increased public access and inappropriate PPI use. This review aims to give a critical appraisal of current literature and to analyze a possible relationship between renal disorders and PPI use. A plethora of observational pharmacoepidemiological studies link PPI therapy to the development of acute interstitial nephritis (AIN). Most of these studies show a higher risk fo...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2020 Category: Urology & Nephrology Authors: Schiffl H, Al-Nemnem E, Lang SM Tags: Saudi J Kidney Dis Transpl Source Type: research

Low serum albumin a predictor sign of the incidence of peritoneal dialysis-associated peritonitis? A quasi-systematic review.
Abstract Peritonitis is associated with an increasing morbidity and mortality rate in peritoneal dialysis patients. A number of peritonitis cases result in hypoalbuminemia, and in other cases, peritonitis follows a decline in the serum albumin level. However, it is not clear whether the level of serum albumin can be utilized to predict and prevent the incidence of peritonitis. A quasi-systematic search of the literature was conducted in the following databases: Cochrane, EBSCO, ProQuest, AHMED, CINHAL, MEDLINE, and EMBASE, from January 2008 to January 2018. The data was reviewed and extracted from each study. The ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2020 Category: Urology & Nephrology Authors: Alharbi MA Tags: Saudi J Kidney Dis Transpl Source Type: research

Frequency and etiology of tubulo-interstitial nephritis in an adult renal biopsies in a tertiary renal care hospital: A single-center study.
Abstract Tubulo-interstitial nephritis (TIN) is an important cause of acute renal failure which may progresses to chronic kidney disease (CKD). TIN is often under diagnosed with there are no specific signs and symptoms. As this entity has paramount importance, so we evaluated the frequency and etiological of TIN both acute TIN (ATIN) and chronic tububulo-interstitial nephritis (CTIN) in renal biopsies. This is a retrospective observational, descriptive study carried out in the Department of Nephrology at The Kidney Centre Post Graduate Training Institute from 2004 to 2016. A total of 1560 adult renal biopsies were...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2020 Category: Urology & Nephrology Authors: Qureshi R, Imtiaz S, Dhrolia M, Ahmad A Tags: Saudi J Kidney Dis Transpl Source Type: research

Anti-C1q antibodies in lupus nephritis and their correlation with the disease activity.
Abstract Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disorder. Renal involvement usually develops in the first few years of illness and should be detected early by periodic urine analysis and quantitation of proteinuria. The aim of our work was to evaluate the biological marker [anti-complement 1q antibodies (anti-C1q Ab)] in lupus nephritis (LN) patients and its correlation to SLE disease activity. Sixty-five subjects were divided into four groups; Group I: SLE patients with LN (proteinuria>0.5 g/day), Group II: SLE patients without LN (all of them had a lupus flares rather than nephr...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2020 Category: Urology & Nephrology Authors: Emad G, Al-Barshomy SM Tags: Saudi J Kidney Dis Transpl Source Type: research

Serum cytokeratin 18 level is associated with dietary intake and serum triglycerides level in hemodialysis patients.
We examined the association of dietary intake and lipid profile with serum CK18 level among hemodialysis (HD) patients. Ninety HD patients according to inclusion and exclusion criteria were included in the study. An analysis of clinical characteristics, anthropometric indices, dietary intake, and lipid profile revealed a significant association between serum CK-18 and diabetes, metabolic syndrome, body mass index (BMI), triglyceride (TG), aspartate aminotransferase (AST), alanine aminotransferase (ALT), energy intake (EI), protein intake (PI), and saturated fatty acid (SFA). In a multiple stepwise regression model, after a...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2020 Category: Urology & Nephrology Authors: Haghighat N, Zare M, Vaziri NM, Hosseini B, Sohrabi Z, Bazyar H, Alipour M, Shafei M Tags: Saudi J Kidney Dis Transpl Source Type: research

Novel biomarkers of acute kidney injury following living donor liver transplantation.
Abstract Urinary biomarkers such as neutrophil gelatinase-associated lipocalin (NGAL) and renalase were recently studied for their potential role in the early detection of acute kidney injury (AKI) in patients with cirrhosis. Our study was conducted on 50 patients with end-stage liver disease undergoing living donor liver transplantation. The patients were divided into two groups: Group I contained 23 patients with AKI who had undergone liver transplantation and Group II included 27 non-AKI patients who had undergone liver transplantation. Serum renalase and NGAL levels were measured by ELISA; renalase was measure...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2020 Category: Urology & Nephrology Authors: Mogawer MS, El-Rahman El-Shazly MA, Ali AY, Abd El-Ghany AM, Elhamid SA Tags: Saudi J Kidney Dis Transpl Source Type: research