Accuracy of GFR estimation formula in determination of glomerular filtration rate in kidney donors: Comparison with 24 h urine creatinine clearance.
Abstract To determine the accuracy of estimated glomerular filtration rate (eGFR) using the modification of diet in renal disease (MDRD), Cockcroft-Gault (CG), and chronic kidney disease epidemiology (CKD-EPI) formulas in potential kidney donors compared with 24-h urine creatinine clearance, we studied 207 potential live kidney donors in our center. There were 126 (60.9%) males and 81 (39.1%) females. Male:female ratio was 1.6:1. The age of the donors ranged from 18-58 years, with mean age of 35.30 ± 9.23 years and most of the individuals were below 40 years of age. The body mass index (BMI) was calculated ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Hafeez AR, Idrees MK, Akhtar SF Tags: Saudi J Kidney Dis Transpl Source Type: research

Restless legs syndrome in hemodialysis patients.
Abstract Restless legs syndrome (RLS) is a neurological disorder characterized by uncomfortable sensation of paresthesia in legs that subsequently causes involuntary and continuous movement of the lower limbs, especially at rest. Its prevalence in hemodialysis is more than that in the general population. Different risk factors have been suggested for RLS. We studied the prevalence and risk factors of RLS in 137 hemodialysis patients followed up at our center. The patients completed at least three months on dialysis and fulfilled four criteria for the diagnosis of RLS. We compared the patients with and without RLS,...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Rafie S, Jafari M, Azizi M, Bahadoram M, Jafari S Tags: Saudi J Kidney Dis Transpl Source Type: research

The effect of depression and anxiety on the performance status of end-stage renal disease patients undergoing hemodialysis.
Abstract Individuals who are diagnosed with end-stage renal disease (ESRD) undergo major changes in lifestyle. The present cross-sectional study was conducted to identify the relationship between patients who undergo hemodialysis (HD) and their performance status, and how it is influenced by the presence of the level of depression and anxiety. A total of 50 patients were recruited from HD centers in and around Chennai. The patients were screened using the General Health Questionnaire to screen for co-morbid psychiatric conditions. The patients were assessed for depression and anxiety, and their performance status ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Rajan EJ, Subramanian S Tags: Saudi J Kidney Dis Transpl Source Type: research

Outcome of patients with multiple myeloma and renal failure on novel regimens.
Abstract Renal involvement occurs in 20-40% of newly diagnosed multiple myeloma (MM) patients, and diagnosis of myeloma is frequently made after investigation for unexplained renal disease. This is a retrospective study between 2006 and 2013 in which 57 consecutive patients seen at the Nephrology Unit with diagnosis of MM were enrolled. MM was diagnosed for the first time because of renal dysfunction and/or proteinuria in these patients. The mean age of the patients (65% male) was 58.3 ± 12.7 years. The median baseline serum creatinine was 3.5 mg/dL (1.4-14.5). Anemia (hemoglobin 10.5 mg/dL) in 35% of patie...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Soleymanian T, Soleimani A, Musavi A, Mojtahedi K, Hamid G Tags: Saudi J Kidney Dis Transpl Source Type: research

Five years renal transplantation data: Single-center experience from Iraq.
Abstract Renal transplantation is the treatment of choice for patients with end-stage renal disease. In Iraq, renal transplantation started in 1973 and has continued until now with live donor transplantation, since deceased donor transplant program is not approved as yet. Long-term transplant data are still scarce. The aim of our study is to present data on transplantation and medical follow-up at one year and, survival analysis at one, three and five years. A total of 250 renal transplantations were performed at the Nephrology and Renal Transplantation Center, Baghdad between January 2009 and January 2014. It is ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Ali AA, Al-Saedi AJ, Al-Mudhaffer AJ, Al-Taee KH Tags: Saudi J Kidney Dis Transpl Source Type: research

Prevalence and determinants of microalbuminurea among type 2 diabetes mellitus patients, Baghdad, Iraq, 2013.
Abstract Microalbuminuria (MAU) is an early marker of diabetic nephropathy (DN), which accounts for a significant reduction in life expectancy of diabetic patients. The progression of DN from the appearance of clinical proteinuria to end stage renal failure is usually irreversible. Increased levels of urinary albumin secretion may represent a more generalized vascular damage. This is the first study conducted in Iraq to determine the prevalence and potential risk factors of MAU among Type 2 diabetes mellitus (T2DM) patients. A cross-sectional study was conducted on a systematic random sample of 224 eligible T2DM p...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Ali AA, Al Lami FH Tags: Saudi J Kidney Dis Transpl Source Type: research

Graft function and nutritional parameters in stable postrenal transplant patients.
Abstract Bioelectrical impedance analysis (BIA) is a method for the assessment of nutritional status. We studied the effect of graft function on nutritional status in postrenal 45 transplant patients with borderline to good allograft function using BIA. The patients had a mean serum creatinine of 1.42 ± 0.42 mg% and mean glomerular filtration rate (GFR) of 45.1 ± 14.1 mL/min. Based on BIA-derived GFR, the patients were divided into two groups; group 1: borderline graft function GFR
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Saxena A, Sharma RK, Gupta A Tags: Saudi J Kidney Dis Transpl Source Type: research

Identification of high-risk population and prevalence of kidney damage among asymptomatic central government employees in Delhi, India.
Abstract Chronic kidney disease (CKD) has attained epidemic proportions in India due to increased incidence of diabetes and hypertension (HTN). It was surmised that identification of only high-risk groups (HRGs) through a questionnaire would be sufficient to identify cases of kidney damage (KD). The study attempted to device a questionnaire to classify the subjects in to HRG and low-risk group (LRG) and assess the extent of early KD. The central government employees were classified into HRG and LRG based on "SCreening for Occult REnal Disease (SCORED)" and "EXTENDED" questionnaire formulated af...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Mahapatra HS, Gupta YP, Sharma N, Buxi G Tags: Saudi J Kidney Dis Transpl Source Type: research

Pattern of renal diseases in children: A developing country experience.
Abstract Spectrum of renal disease varies in different ethnic population, geographical location, and by environmental factors. The purpose of this study was to find out the clinical spectrum and occurrence of different pediatric renal diseases at a teaching hospital in the Eastern part of Nepal. All cases of renal diseases from one month to 15 years of age, attending the pediatric renal outpatient department and/or were admitted to the wards during the period of February 2012 to January 2013, were included in the study. Detailed clinical and laboratory evaluations were performed on all patients. Diseases were cate...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Yadav SP, Shah GS, Mishra OP, Baral N Tags: Saudi J Kidney Dis Transpl Source Type: research

Occurrence of double primary malignancies in an African renal transplant recipient.
Abstract A 63-year-old African male with end stage renal disease who received a renal transplantation from his daughter after successful treatment of hepatitis C virus, type 1 genotype developed metastatic Kaposi's sarcoma and subsequently adenocarcinoma of the prostate. He was successfully treated with chemotherapy and reduction of immunosuppression and switch over to rapamycin. PMID: 26997394 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Mohan P, Yuvaraj A, Abraham G, Kurien A, Abraham A, Mathew M, Saravanan S, Nair S Tags: Saudi J Kidney Dis Transpl Source Type: research

Early recurrence of proliferative glomerulonephritis with monoclonal immunoglobulin deposits in a renal allograft.
Abstract Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMIDs) is a clinico-pathologic entity, the recurrence of which in the renal allograft has only recently been described. A 55-year-old male presented with rapid deterioration of renal function. Light microscopy showed membranoproliferative glomerulonephritis with kappa light chain restriction and only one sub-class of IgG. He subsequently underwent renal transplant. Two months later, he developed acute graft dysfunction. Renal biopsy showed a recurrence of the disease. Work up for multiple myeloma was positive. Membranoproliferativ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Tewari R, Joshi K, Kumar A, Rayat CS, Iyer R, Sakhuja V, Minz M Tags: Saudi J Kidney Dis Transpl Source Type: research

Successful management of chylous ascites: A report of two cases.
We present two cases of postoperative chylous ascites, one following a bilateral nephrectomy, the other following orthotopic heart transplantation. Treatment is typically conservative with the aim to alleviate abdominal distension and reduce the flow of lymph into the mesenteric lymph nodes. Postsurgical chylous ascites has high cure rate with conservative therapy alone. Therapeutic paracentesis, diuretics, salt restriction, a high-protein, low-fat, mediumchain triglyceride diet, and parenteral nutrition are considered in chronic cases. The effects of longterm paracentesis on patients remains to be seen. In patients requir...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Alam SE, Kar SM, Kar PM Tags: Saudi J Kidney Dis Transpl Source Type: research

Cerebral venous thrombosis and secondary polycythemia in a case of nephrotic syndrome.
We report an unusual combination of both these complications in a case of nephrotic syndrome due to minimal change disease that was treated successfully. There was prompt and complete remission of nephrotic syndrome with steroid therapy, concurrent with complete resolution of polycythemia and CVT. PMID: 26997397 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Nagaraju SP, Bairy M, Attur RP, Sambhaji CJ Tags: Saudi J Kidney Dis Transpl Source Type: research

Asymptomatic pontine and extra-pontine lesions in a patient with end-stage renal disease.
Abstract Osmotic demyelination syndrome leading to central pontine/extra-pontine myelinolysis (CPM/EPM) occurs mainly in patients with history of alcohol abuse, malnourishment, following liver transplantation and less commonly, in association with other systemic diseases. Asymptomatic CPM/EPM is rare. Patients with end-stage renal disease (ESRD) who develop CPM/EPM are usually symptomatic with florid neurologic manifestations. Herein, we present a patient with ESRD on maintenance hemodialysis who was incidentally detected to have pontine and extra-pontine lesions suggestive of myelinolysis without any neurologic s...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Yadav RK, Das CJ, Bagchi S, Agarwal S Tags: Saudi J Kidney Dis Transpl Source Type: research

An unusual case of hematuria in a young female: renal artery embolism, mitral stenosis, and sinus rhythm.
We describe an unusual case of a young female who presented with sudden onset right flank pain, vomiting, anorexia, and hematuria, and was found to have thrombotic occlusion of the distal right renal artery. Although she denied any previous cardiac history, detailed cardiovascular examination revealed the presence of severe rheumatic mitral stenosis without any evidence of AF or left atrial clot. She was initially managed conservatively using low molecular weight heparin followed by oral anticoagulation with resolution of symptoms. A successful balloon mitral valvotomy was performed six weeks later. The patient is asymptom...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Kumar A, Kapoor A, Kumar S Tags: Saudi J Kidney Dis Transpl Source Type: research

Takayasu arteritis associated with severe renovascular hypertension.
We report a 16-year-old girl in whom TA manifested mainly with a sudden decrease in visual acuity and severe arterial hypertension in both legs. Bilateral radial pulses were absent. Ultrasound showed renal size asymmetry and raised the possibility of renal artery stenosis. The diagnosis of TA was confirmed by computed tomography angiography, which showed a thickened abdominal aortic wall and narrowing of its lumen. In addition, occlusions of left renal artery and of both left and right subclavian arteries were observed. Hypertension was hardly under control by a combination of three antihypertensive drugs. The outcome was ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Hassani M Tags: Saudi J Kidney Dis Transpl Source Type: research

Quadriparesis due to Gitelman's syndrome diagnosed with thiazide diuretic test response.
Abstract Gitelman's syndrome is characterized by hypocalciuria, severe hypomagnesemia, and prominent muscular involvements such as fatigue, weakness, cramps, and tetany. It is due to mutations in the thiazide sensitive NaCl co-transporter in the distal convoluted tubule. The administration of thiazide diuretics may induce a subnormal increase of urinary Cl- excretion in patients with Gitelman's syndrome, consistent with the hypothesis that less than normal Cl- is reabsorbed by the thiazide-inhibitable transporter in Gitelman's syndrome. Thus, we report a case of Gitelman's syndrome presenting with quadriparesis di...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Mukhopadhyay S, Jana S, Chatterjee A, Roy M, Sarkar A, Mukhopadhyay J Tags: Saudi J Kidney Dis Transpl Source Type: research

Posterior reversible encephalopathy syndrome in a hypertensive patient with renal failure.
We report a case of PRES which was associated with hypertensive crisis in a patient with renal failure. Antihypertensive therapy and hemodialysis resulted in complete recovery. PMID: 26997402 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Aatif T, El Farouki MR, Benyahia M Tags: Saudi J Kidney Dis Transpl Source Type: research

Acute renal artery spasm during live kidney transplant surgery due to iatrogenic cause.
PMID: 26997403 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Singh D, Butala BP, Parikh GP Tags: Saudi J Kidney Dis Transpl Source Type: research

WT1 mutations in steroid-resistant idiopathic nephrotic syndrome.
PMID: 26997404 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Mishra OP, Singh AK, Abhinay A, Narayan G, Prasad R, Batra VV Tags: Saudi J Kidney Dis Transpl Source Type: research

Recurrent acute kidney injury in a young female: A rare presentation of ureteral endometriosis.
PMID: 26997405 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Pant P, Prakash S, Dwivedi AN, Prakash J Tags: Saudi J Kidney Dis Transpl Source Type: research

Hypertension and diabetes remain the main causes of chronic renal failure in Fars Province, Iran 2013.
PMID: 26997406 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Malekmakan L, Malekmakan A, Daneshian A, Pakfetrat M, Roosbeh J Tags: Saudi J Kidney Dis Transpl Source Type: research

The need to automate urinary creatinine ratios adjusted for the predicted daily creatinine excretion.
PMID: 26997407 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Abutaleb N Tags: Saudi J Kidney Dis Transpl Source Type: research

[In Process Citation].
Authors: PMID: 26950962 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Tags: Saudi J Kidney Dis Transpl Source Type: research

Effect of pediatric liver transplantation on renal function.
Abstract The aim of this review is to define the incidence of renal dysfunction among pediatric liver transplant (LT) survivors, to identify the associated risk factors and to outline the therapeutic options. Renal dysfunction is a common problem after pediatric LT. The measured glomerular filtration rate is considered the "gold-standard" for assessment of renal function. Renal dysfunction in pediatric LT recipients is multifactorial. Renal-sparing immunosuppressive strategies are essential to reverse renal dysfunction and to prevent end-stage renal disease. PMID: 26787559 [PubMed - in process] (Sou...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Isa HM, Mohamed AM, Alderazi AE Tags: Saudi J Kidney Dis Transpl Source Type: research

Multiple myeloma: Diagnosis and management issues in patients with pre-existing chronic kidney disease.
Abstract Multiple myeloma is one of the most common malignancies encountered in clinical practice. Renal involvement in myeloma is a well-recognized entity. Although rare, another special situation that a nephrologist can encounter is myeloma occurring in a patient with preexisting chronic kidney disease (CKD) due to other etiologies. Anemia, bone pains and hypercalcemia, which commonly indicate the diagnosis of myeloma in the general population, are not useful in the presence of CKD. The sensitivity and specificity of serum free light chain assay is decreased in the presence of renal failure. Chemotherapy-related...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Vadlamudi S, Annapareddy SN Tags: Saudi J Kidney Dis Transpl Source Type: research

The effects of cinacalcet treatment on bone mineral metabolism, anemia parameters, left ventricular mass index and parathyroid gland volume in hemodialysis patients with severe secondary hyperparathyroidism.
Abstract The aim of this study was to investigate the effects of cinacalcet therapy on anemia parameters, bone mineral metabolism, left ventricular mass index (LVMI) and parathyroid gland volume in hemodialysis (HD) patients with secondary hyperparathyroidism. Twenty-five HD patients (M/F: 11/14, mean age: 45.2 ± 17.9 years, mean HD duration: 96.4 ± 32.7 months) were included in this prospective pilot study. The indication to start calcimimetic therapy was persistent serum levels of parathyroid hormone (PTH)>1000 pg/mL, refractory to intravenous (i.v.) vitamin D and phosphate-binding therapy. The ...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Torun D, Yildiz I, Micozkadioglu H, Nursal GN, Yigit F, Ozelsancak R Tags: Saudi J Kidney Dis Transpl Source Type: research

Erectile dysfunction in hemodialysis patients.
Abstract Erectile dysfunction (ED) is a common problem seen among patients on hemodialysis (HD), but it is still a taboo subject in our country. The attention given to this sexual problem remained low, and the prevalence of ED among these patients has not been well characterized. We carried out this study in order to determine the prevalence and severity of ED in HD patients. We conducted a descriptive cross-sectional study in our HD unit in March 2013. ED was evaluated using the International Index Erection Function. Thirty patients with a mean age of 49.1 years were eligible for this study. The main causes of ch...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Gorsane I, Amri N, Younsi F, Helal I, Kheder A Tags: Saudi J Kidney Dis Transpl Source Type: research

How are families taught to look after their children on peritoneal dialysis?
This study was performed to examine the PD teaching programs for parents of children with end-stage renal disease (ESRD) and to explore the issues related to educating parents of children with ESRD. A survey method was used to carry out the research through the distribution of self-completed questionnaires to pediatric dialysis units (ten units) in Saudi Arabia in both governmental and non-governmental hospitals. The questionnaire content was identified using information gained from other research performed in the field of home PD training. The questionnaire was piloted with experienced renal nurses. Questionnaires were di...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Alhameedi RS, Collier J Tags: Saudi J Kidney Dis Transpl Source Type: research

Assay of urinary protein-bound sialic acid can differentiate steroidsensitive nephrotic syndrome from steroid-resistant cases.
Abstract The protein selectivity index as measured from the ratio of urinary immunoglobulin to albumin failed to differentiate between steroid-sensitive (SS) and steroid-resistant (SR) cases of nephrotic syndrome (NS). Sialic acid contributes negative charges to many plasma proteins. The negative charge is a determinant of protein excretion rate. The prognostic significance of assay of urinary excretion of protein-bound sialic acid in NS has not been evaluated. Hence, the present study was designed to evaluate whether measurement of urinary protein bound sialic acid (UPBSA) can be used as a marker to differentiate...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Gopal N, Koner BC, Bhattacharjee A, Bhat V Tags: Saudi J Kidney Dis Transpl Source Type: research

Amelioration of cisplatin-induced nephrotoxicity by ethanolic extract of Bauhinia purpurea: An in vivo study in rats.
Abstract Our objective is to study the nephroprotective activity and antioxidant potential of Bauhinia purpurea unripe pods and bark against cisplatin-induced nephrotoxicity. Healthy adult albino rats of either sex (150-200 g) were randomly divided into six groups of six animals each Group I (vehicle control) and Group II (negative control). Group III (BBE200) and Group IV (BBE400) were administered the ethanolic extract of Bauhinia purpurea bark in doses of 200 and 400 mg/kg/day p.o., respectively, and Group V (BPE200) and Group VI (BPE400) were administered the ethanolic extract of Bauhinia purpurea unripe pods ...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Rana MA, Khan RA, Nasiruddin M, Khan AA Tags: Saudi J Kidney Dis Transpl Source Type: research

Plasma neutrophil gelatinase-associated lipocalin as a marker for the prediction of worsening renal function in children hospitalized for acute heart failure.
Abstract Acute heart failure (AHF) is frequently associated with worsening renal function in adult patients. Neutrophil gelatinase-associated lipocalin (NGAL) serves as an early marker for acute renal tubular injury. To assess the role of plasma NGAL in predicting worsening renal function (WRF) in children with AHF, we studied 30 children hospitalized for AHF; children with history of chronic renal disease or on nephrotoxic drugs were excluded. Twenty ageand sex-matched healthy children were included in the study as a control group. Echocardiographic examination was performed on admission. Blood urea nitrogen (BUN...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Elsharawy S, Raslan L, Morsy S, Hassan B, Khalifa N Tags: Saudi J Kidney Dis Transpl Source Type: research

N-acetylcysteine and/or ascorbic acid versus placebo to prevent contrast-induced nephropathy in patients undergoing elective cardiac catheterization: The NAPCIN trial; A single-center, prospective, randomized trial.
This study is aimed to evaluate the effect of a high dose of N-acetylcysteine (NAC) plus hydration, a low dose of NAC plus ascorbic acid and hydration or hydration alone on the prevention of CIN in high-risk patients undergoing elective coronary artery intervention. We conducted a randomized, prospective, placebo-controlled trial of 105 high-risk patients undergoing elective cardiac catheterization. The patients were divided into three different groups: Group A (n = 30), NAC 1200 mg orally before angiography and 1200 mg orally twice daily for three doses along with good hydration; Group B (n = 30), NAC 600 mg before angiog...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Habib M, Hillis A, Hammad A Tags: Saudi J Kidney Dis Transpl Source Type: research

Prevalence of calcified carotid artery atheromas on panoramic radiographs of renal stone patients.
Abstract The aim of the present study was to evaluate the prevalence of calcified carotid artery atheromas detected on panoramic radiographs of patients with renal stones and to assess the correlation of renal stones and carotid artery calcifications (CAC). Panoramic radiographs of 120 renal stone patients (76 males and 44 females) and 120 controls (68 males and 52 females) were examined for any calcifications in the carotid artery. The mean age of the patients with renal stones and controls was 40.6 ± 7.8 years and 41.1 ± 6.7 years, respectively. A total of 25 (20.8%) patients with renal stones and ...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Patil S, Maheshwari S, Khandelwal S, Malhotra R, Desmukh A Tags: Saudi J Kidney Dis Transpl Source Type: research

The predictive factors for relapses in children with steroid-sensitive nephrotic syndrome.
Abstract Most patients with steroid-sensitive nephrotic syndrome (SSNS) have frequent relapses (FR); this is considered one of the main problems because of its association with a high incidence of complications. The aim of our study was to evaluate the different factors that might be associated with the occurrence of relapse in SSNS. This is a retrospective study of 80 patients with SSNS conducted at the Pediatric Nephrology Clinic in the Al-Kadhymia Teaching Hospital between January 2011 and November 2011. The study patients were divided into two groups: FR and infrequent relapses (IFR). The age of the study pati...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Ali SH, Ali AM, Najim AH Tags: Saudi J Kidney Dis Transpl Source Type: research

Attention deficit hyperactivity disorder in children with primary monosymptomatic nocturnal enuresis: A case-control study.
Abstract Attention deficit hyperactivity disorder (ADHD) is one of the most common childhood neurological disorders. The aim of this study was to investigate ADHD in children with primary monosymptomatic nocturnal enuresis (PMNE) and compare it with healthy children. A total of 100 five to 16-year-old children with PMNE and 100 healthy children without NE were included in this case-control study as the cases and control groups, respectively. Subjects were selected from children who were referred to the pediatric clinic of the Amir Kabir Hospital of Arak, Iran, based on inclusion and exclusion criteria. ADHD was di...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Yousefichaijan P, Sharafkhah M, Salehi B, Rafiei M Tags: Saudi J Kidney Dis Transpl Source Type: research

The relationship between malnutrition subgroups and volume parameters in pre-dialysis patients.
tük IO Abstract There are two types of malnutrition in patients with chronic renal failure (CRF); type 1 and type 2. The aim of this study was to investigate the relationship between malnutrition and inflammation and also the relationship between malnutrition and volume status. Ninety-four pre-dialysis CRF patients were included in the study. Nutritional status of the patients was calculated using the subjective global assessment. Scores of 1-5 were given according to the severity of the symptoms and physical examination findings. Serum inflammation markers [high-sensitive C-reactive protein (hs-CRP), interle...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Kutsal DA, Kürşat S, İnci A, Ulman C, Ütük IO Tags: Saudi J Kidney Dis Transpl Source Type: research

Evaluation of administration of oral N-acetylcysteine to reduce oxidative stress in chronic hemodialysis patients: A double-blind, randomized, controlled clinical trial.
This study was designed to assess the efficacy of N-acetylcysteine (NAC) on the reduction of oxidative stress in chronic hemodialysis (HD) patients through measurement of total serum anti-oxidant capacity. In this randomized, double-blind, controlled clinical trial, the efficacy and safety of NAC in reduction of oxidative stress was evaluated in 40 chronic HD patients. The study was conducted at the HD Department of the Golestan Hospital, Ahvaz, Iran. Data were analyzed using SPSS version 19. Paired samples test showed that the mean score of the serum level of total anti-oxidant capacity (TAC) increased from 26.39 ±...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Shahbazian H, Shayanpour S, Ghorbani A Tags: Saudi J Kidney Dis Transpl Source Type: research

A comparison of definitions of contrast-induced nephropathy in patients with normal serum creatinine.
This study included 206 patients with normal serum creatinine who underwent coronary angiography/angioplasty. Serum creatinine level and glomerular filtration rate (GFR) were measured before and on the second and fifth days after contrast administration. The incidence of CIN based on a 25% increase in serum creatinine was calculated and compared with the incidence based on a 25% decrease in GFR or an increase of at least 0.5 mg/dL in serum creatinine. Of 206 patients, 127 were male (61.7%) and 79 were female (38.3%); the mean age was 59.56 ± 10.3 years. The prevalence of CIN was 30% based on a 25% increase in serum ...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Khatami MR, Nikravan N, Salari-Far M, Davoudi S, Pahlavan-Sabbagh MR Tags: Saudi J Kidney Dis Transpl Source Type: research

Coping strategies and socio-demographic characteristics among Jordanian caregivers of patients receiving hemodialysis.
Abstract Individuals who care for family members receiving chronic hemodialysis (HD) are likely to experience burdens that may adversely impact their patients. Effective coping strategies are shaped by various factors, including sociodemographic characteristics. To assess the relationship between caregivers and their patients, we studied 225 family-member caregivers of chronic HD patients through answering the Ways of Coping Questionnaire-Revised. Sociodemographic data, including caregiver age, gender, educational level, relationship to the patients, length of care time and weekly hours of caregiving were analyzed...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Alnazly E Tags: Saudi J Kidney Dis Transpl Source Type: research

Mechanical complications of continuous ambulatory peritoneal dialysis: Experience at the Ibn Sina University Hospital.
Abstract Peritoneal dialysis is a new renal replacement therapy recently introduced in Morocco since 2006. Continuous ambulatory peritoneal dialysis has proven to be as effective as hemodialysis. However, it is associated with several complications. The aim of this study was to evaluate the outcome of complications in patients treated with peritoneal dialysis at our center. The nature of non-infectious complications was noted during follow-up in these patients. Fiftyseven complications were noted among 34 patients between June 2006 and June 2014. Catheter migration was the most common complication (36.8%), followe...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Flayou K, Ouzeddoun N, Bayahia R, Rhou H, Benamar L Tags: Saudi J Kidney Dis Transpl Source Type: research

Epidemiology and risk factors of chronic kidney disease in the El-Sharkia Governorate, Egypt.
Abstract End-stage renal disease (ESRD) is increasing worldwide. Renal replacement therapy and kidney transplantation are increasing the burden on health systems. Various risk factors can lead to this disease. In this work, we tried to study the epidemiology and risk factors of chronic kidney diseases (CKDs) in one of the Egyptian areas (El-Sharkia Governorate), and from this study we can get some data about the distribution and most common causes of this disease. A cross-sectional study was conducted at 15 dialysis centers in governmental hospitals in ElSharkia, Egypt. We used a questionnaire and direct interview...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Ghonemy TA, Farag SE, Soliman SA, El-Okely A, El-Hendy Y Tags: Saudi J Kidney Dis Transpl Source Type: research

Knowledge, attitudes and beliefs of first-degree relatives of patients with chronic kidney disease toward kidney donation in Nigeria.
This study assessed the attitudes of relatives of patients with chronic kidney disease (CKD) toward kidney donation. This was a cross-sectional survey of relatives of patients with CKD attending the nephrology service of our hospital. The respondents' socio-demographic characteristics and knowledge and beliefs about kidney transplantation, as well as their willingness to donate a kidney, were assessed using a self-administered questionnaire. There were 161 respondents who returned completed questionnaires; the mean age of the respondents was 34.8 ± 12.6 years and 52.2% of them were female. About 85.1% of the respond...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Bello BT, Raji YR Tags: Saudi J Kidney Dis Transpl Source Type: research

Ethical and legal issues in renal transplantation in Nigeria.
Abstract With the increasing number of patients being offered kidney transplantation by many centers in the developing world, it is not unexpected that there would be attendant ethical and legal issues even when the selection process for transplantation seems medically justified. Because of the inadequate infrastructure for hemodialysis and peritoneal dialysis, coupled with the challenges of logistics for maintenance dialysis, transplantation would seem to be the best option for patients with end-stage renal failure, even in developed economies where these can easily be tackled. The main issues here revolve around...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Ajayi SO, Raji Y, Salako BL Tags: Saudi J Kidney Dis Transpl Source Type: research

Prevalence and clinical and laboratory characteristics of kidney disease in anti-retroviral-naive human immunodeficiency virus-infected patients in South-South Nigeria.
This study was conducted on patients presenting at the University of Benin Teaching Hospital, Benin City in South-South Nigeria for six months. The patients' demographic data and clinical, hematological and biochemical parameters were assessed. Their glomerular filtration rate (GFR) was calculated and the protein excretion was assessed from the protein- creatinine ratio. Data were analyzed using statistical software program SPSS version 15.0. Threehundred and eighty-three patients with a mean age of 35.39 ± 8.78 years and a male: female ratio of 1:1 were studied; 53.3% had evidence of kidney disorder. The main clini...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Okafor UH, Unuigbe EI, Chukwuonye E Tags: Saudi J Kidney Dis Transpl Source Type: research

Multiple intracranial tuberculomas in a post-kidney transplant patient.
We report a post-kidney transplant patient who had multiple ring-like lesions on contrast-enhanced magnetic resonance imaging (MRI). Based on the results of MRI and biopsy specimen, the patient was diagnosed with multiple intracranial tuberculomas. He was treated successfully with a standard quadruple therapy of rifampicin, isoniazid, ethambutol and pyrazinamide. PMID: 26787580 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Yadegarynia D, Merza MA, Sali S, Seghatoleslami ZS Tags: Saudi J Kidney Dis Transpl Source Type: research

Chromophobe renal cell carcinoma occurring in the renal allograft of a transplant recipient presenting with weight loss.
Abstract The incidence of renal cell carcinomas (RCCs) in renal transplant recipients is reported as 1.1-1.5% in the native kidneys and 0.22-0.25% in the renal allograft. There are no data to support routine surveillance for tumors in transplant recipients. Most reported cases of RCCs occurring in renal allografts were incidental findings in asymptomatic patients. Herein, we report the second case of lone chromophobe RCC (ChRCC) of the renal allograft presenting with weight loss. Loss of weight is a presenting symptom in one-third of ChRCCs occurring in the native kidneys in the general population. Based on the ag...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Althaf MM, Al-Sunaid MS, Abdelsalam MS, Alkorbi LA, Al-Hussain TO, Dababo MA, Haq N Tags: Saudi J Kidney Dis Transpl Source Type: research

Mandibular mass in a child on hemodialysis.
Abstract We here with report a 13-year-old female patient on regular hemodialysis for the past five years who presented with a large mandibular mass. This was detected to be a brown tumor due to severe renal osteodystrophy as a complication of secondary hyperparathyroidism. The tumor did not regress even with intensive treatment with intravenous active vitamin D and needed surgical removal. PMID: 26787582 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Youssef DM, Mohammed FF, Adham T Tags: Saudi J Kidney Dis Transpl Source Type: research

Evans syndrome and its link with systemic lupus erythematosus.
Abstract Evans syndrome is a rare syndrome associated with the presence of autoimmune hemolytic anemia and simultaneous or sequential development of thrombocytopenia. It was first described by Evan and Duane in 1951. It is one of the rare presenting features of autoimmune disorders, especially systemic lupus erythematosus (SLE), and sometimes may even precede the onset of disease. Primary Evans syndrome with no cause is very rare and is seen in children. Here, we describe a case of secondary Evans syndrome with severe hemolytic anemia leading to acute kidney injury and recovery thereafter only to develop lupus nep...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Mendonca S, Srivastava S, Kapoor R, Gupta D, Gupta P, Sharma ML Tags: Saudi J Kidney Dis Transpl Source Type: research

Recurrence of nephrotic syndrome following kidney transplantation in a child with congenital nephrotic syndrome.
We report a case of a female child with CNS who presented with nephrotic state at first month of age and became dialysis dependent at 17 months of age. After seven months of continuous ambulatory peritoneal dialysis, she received a kidney from a deceased donor. Eight months after transplantation, she presented with a full-blown feature of nephrotic syndrome. She responded well to rituximab. PMID: 26787584 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2016 Category: Urology & Nephrology Authors: Derakhshan A, Derakhshan D, Fallahzadeh MH, Basiratnia M Tags: Saudi J Kidney Dis Transpl Source Type: research