Ureteral obstructive nephropathy due to compression by intrinsic endometriosis of the ovary.
PMID: 30152447 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2018 Category: Urology & Nephrology Authors: Bono L, Li Cavoli G, Giammarresi C, Turdo R, Li Cavoli TV, Oliva B, Caputo F Tags: Saudi J Kidney Dis Transpl Source Type: research

Prevention of severe acute kidney injury by implementation of care bundles: Some progress but still a lot of work ahead.
Abstract Routine health data, dating from 1990 to 2015, show a dramatic rise in the incidence of acute kidney injury (AKI) in the general population and an apparent increase in acute dialysis (AKI-D) prompting calls for improvement of care in AKI patients. Recent reports suggest flattening of population-based AKI occurrence rates or declining frequencies of AKI or AKI-D in subgroups of high-risk patients with known onset of AKI. These temporal changes in AKI occurrence relate at least in part to the widespread implementation of AKI prevention care bundles. Nevertheless, AKI frequencies and AKI morbidity and mortal...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Schiffl H Tags: Saudi J Kidney Dis Transpl Source Type: research

Improvement in dialysis-related adverse events with use of body composition monitoring.
This study aims to utilize body composition monitor (BCM) device to achieve euvolemic status in problematic dialysis patients and to evaluate its clinical outcome. One hundred and five hemodialysis (HD) patients were enrolled based on difficulty in achieving dry weight. The reasons for enrollment in the study were (a) recurrent intradialytic hypotension, (b) intradialytic hypertension, (c) intradialytic muscle cramps, or (d) the presence of comorbid conditions that make clinical assessment of dry weight difficult (e.g., cirrhosis of liver, heart failure, severe malnutrition, or morbid obesity). Following initial assessment...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Raza SH, Hashmi MN, Elairon P, Riolo AH, Hejaili F, Al-Sayyari AA Tags: Saudi J Kidney Dis Transpl Source Type: research

Correlation and discrepancy of phospholipase A2 receptor staining in membranous nephropathy in paraffin-embedded kidney biopsies.
Abstract Distinguishing primary from secondary forms of membranous nephropathy (MN) in paraffin-embedded kidney biopsies is challenging. Previous studies have measured the accuracy, sensitivity, and specificity of phospholipase A2 receptor (PLA2R) on MN. However, due to the absence of a gold standard method for diagnosis, further studies are necessary. Here, we measure the correlation and discrepancy of PLA2R on MN in paraffin-embedded kidney biopsies by correlating PLA2R findings with immunofluorescence (IF), light microscopy (LM), and electron microscopy (EM) results. A total of 116 kidney biopsies were investig...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Alwahaibi NY, Alrawahi UY, Alriyami MA Tags: Saudi J Kidney Dis Transpl Source Type: research

Fibroblast growth factor-23 as a predictor biomarker of acute kidney injury after cardiac surgery.
Abstract Renal ischemia/reperfusion injury is a major cause of acute kidney injury (AKI). The lack of early biomarkers for predicting AKI has hampered our ability to initiate preventive and therapeutic measures in an opportune way. Fibroblast growth factor 23 (FGF-23) is elevated in chronic kidney disease, but data on FGF-23 in humans with AKI are limited. Herein, we tested whether FGF-23 levels rise early in the course of AKI following cardiac surgery. We prospectively evaluated eighty adult patients who underwent cardiac surgery. Patients were divided into two groups (AKI and non-AKI group) on the basis of wheth...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Shaker AM, El Mohamed E, Samir HH, Elnokeety MM, Sayed HA, Ramzy TA Tags: Saudi J Kidney Dis Transpl Source Type: research

Evaluation of blood pressure in children with idiopathic overactive bladder syndrome.
Abstract Children with an overactive bladder generally exhibit frequency, urgency, and urge incontinence. Often, a child will squat to try to prevent urinary incontinence. The bladder in these children is not anatomically and is functionally, smaller than normal and exhibits strong uncontrolled contractions. The aim of this study was to the evaluation of blood pressure (BP) in children with idiopathic overactive bladder syndrome. In this case-control study, we selected 110 children with overactive bladder as cases and 220 children without overactive bladder as controls. Children with overactive bladder and healthy...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Yousefichaijan P, Khosrobeigi A, Soltani M, Ghandi Y, Mojtahedi F Tags: Saudi J Kidney Dis Transpl Source Type: research

Combined use of Vitamins E and C improve nephrotoxicity induced by colistin in rats.
This study was performed to investigate the protective effect of combined use of Vitamins E and C on colistin-induced tubular damage in rat. Animals were treated with sterile saline, colistin methanesulfonate (CMS), CMS + Vitamin E + Vitamin C, and Vitamin E + vitamin C, respectively, for seven days. Thereafter, animals were sacrificed and the urine N-acetyl-b-D-glucosaminidase (NAG) and gamma-glutamyl transferase (GGT) levels, plasma level of creatinine (Cr), vitamin E and vitamin C, and renal tissue levels of malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), as well as r...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Ghlissi Z, Hakim A, Mnif H, Zeghal K, Rebai T, Boudawara T, Sahnoun Z Tags: Saudi J Kidney Dis Transpl Source Type: research

Nigella sativa prevented liver and renal tissue damage in lipopolysaccharide-treated rats.
Abstract Liver and renal dysfunction accompanying with the tissues' oxidative damage has been reported to occur during Inflammation. Nigella sativa has been well known for its antioxidant and anti-inflammatory effects. The aim of this study was to investigate preventive effects of N. sativa on liver and renal tissue damage in lipopolysaccharide (LPS) -treated rats. The rats were divided into five groups: (1) control; (2) LPS (1 mg/kg, IP, for 10 days), (3-5) N. sativa hydroethanolic extract (100, 200, or 400 mg/kg) before LPS. Compared to LPS group, treatment by the extract decreased alondialdehyde, nitric oxide (...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Beheshti F, Norouzi F, Abareshi A, Khazaei M, Alikhani V, Moussavi S, Biglari G, Soukhtanloo M, Hosseini M Tags: Saudi J Kidney Dis Transpl Source Type: research

Prevalence of cardiac arrhythmia and risk factors in chronic kidney disease patients.
This study aimed to investigate the prevalence of cardiac arrhythmia in CKD patients and to evaluate the relationship between arrhythmia and biochemical and echocardiographic parameters. CKD patients between 18 and 80 years of age were enrolled from the nephrology outpatient clinic. Physical examination, complete blood count, urinalysis biochemical analysis, electrocardiogram, echocardiogram, and 24-h Holter electrocardiogram were performed. Patients with and without cardiac arrhythmia were compared regarding their characteristics, laboratory findings, and echocardiographic parameters. Risk factors for cardiac arrhythmia w...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Kaya B, Paydas S, Aikimbaev K, Altun E, Balal M, Deniz A, Kaypakli O, Demirtas M Tags: Saudi J Kidney Dis Transpl Source Type: research

Pulmonary function tests and plasma nitric oxide levels in pediatric hemodialysis.
This study was performed among 20 patients on regular HD and 20 controls. Participants were subjected to clinical examination, and pulmonary function evaluation was performed using spirometry. The following parameters were obtained as follows: forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), Tüffenau index (FEV1/%FVC), (FEF25%-75%), and peak expiratory flow. Spirometry was carried out before and after HD sessions, and at the same time of clinical assessments, blood samples were taken to measure arterial-blood gas (ABG) and NO levels. There was the statistically significant difference between patien...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Youssef DM, Shokry DM, Elbehidy RM, Mohammed Khedr MK Tags: Saudi J Kidney Dis Transpl Source Type: research

The pathological evaluation of nonneoplastic kidney disorder in tumor nephrectomy specimens.
Abstract Renal cell carcinoma (RCC) comprises 2%-3% of all visceral and 80%-85% of all adult kidney malignancies. Nephrectomy is the treatment of choice for renal tumors. The accurate pathological evaluation of nonneoplastic renal parenchyma in nephrectomy specimens is important for subsequent management. Eighty-two patients with RCC who underwent surgery at Imam Khomeini Hospital, Urmia, Iran, from April 2006 to February 2015 were studied. Paraffin blocks of the hospital archives were stained by hematoxylin and eosin (H and E) and periodic acid-Schiff staining. Microscopic examination was performed on nontumoral ...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Noroozinia F, Makhdoomi K, Behnamfard H, Mohammadi S, Dindarian S, Bagheri M, Mohammadi H Tags: Saudi J Kidney Dis Transpl Source Type: research

Evaluation of interleukin-18 in children with steroid-sensitive nephrotic syndrome before and after using levamisole.
This study was done on 23 children with frequently relapsing SSNS treated with levamisole besides steroids, then followed up three months; 16 males and seven females (mean age: 7.96 years and median 8 years). Clinical and laboratory assessments were done before starting therapy and after three months including cumulative dose of steroids and serum IL-18. We found that IL-18 level showed a significant elevation after three months of levamisole therapy compared to its level before initiation of levamisole therapy, with no relapses in these three months, no reported side effect, and significant reduction of cumulative dose of...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Youssef DM, Abd Al-Atif AM, El-Khateeb SSH, Elshal AS Tags: Saudi J Kidney Dis Transpl Source Type: research

Drug-induced acute interstitial nephritis: Prospective randomized trial comparing oral steroids and high-dose intravenous pulse steroid therapy in guiding the treatment of this condition.
Abstract The most important aspect of treating drug-induced acute interstitial nephritis (AIN) is timely discontinuation of the offending drug. Steroids, oral as well as intravenous (IV), are used in the treatment of drug-induced AIN. The present study was undertaken to compare the efficacy of oral prednisolone versus IV suprapharmacological doses of corticosteroids in the treatment of drug-induced AIN. This prospective randomized controlled study included drug-induced AIN diagnosed on histopathology over a period of two years. Patients were randomized to oral prednisolone (Group A) 1 mg/kg for two weeks or pulse ...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Chowdry AM, Azad H, Mir I, Najar MS, Ashraf BM, Muzafar WM, Ahmed WI Tags: Saudi J Kidney Dis Transpl Source Type: research

Prediction of cardiovascular disease risk using framingham risk score among office workers, Iran, 2017.
Abstract Cardiovascular diseases (CVDs) are leading cause of morbidity and mortality and early identification of risk factors can help reduce mortality from them. The aim of this study was to determine the risk of CVD based on the Framingham Risk Score (FRS) among office workers, Yasuj City, Southwestern Iran. In this descriptive study, 180 workers aged 30-74 years old free of cardiovascular disease were recruited by single-stage stratified cluster sampling from the office of Yasuj City. Analysis showed that 163 workers (90.5%) were at low risk, 12 people (6.6%) at moderate risk, and five people (2.9%) at high 10-...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Nakhaie MR, Koor BE, Salehi SO, Karimpour F Tags: Saudi J Kidney Dis Transpl Source Type: research

Determinants of patency of arteriovenous fistula in hemodialysis patients.
Abstract The arteriovenous fistula (AVF) is the vascular access of the first choice for hemodialysis (HD). Studies on patency of AVF and its affecting factors reveal a high risk for access failure. The aim of this study was to assess the primary and secondary AVF patency and their determinant factors. It was a retrospective, descriptive study conducted in the HD facility of the Nephrology Department in Rabta University Hospital. We included AVF created before December 2009 in end-stage renal disease (ESRD) patients. The end of the follow-up was fixed in December 2013. We included 126 AVFs created in 111 patients; ...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Zouaghi MK, Lammouchi MA, Hassen M, Rais L, Krid M, Smaoui W, Jebali H, Kheder R, Hamida FB, Moussa FB, Fatma LB, Beji S Tags: Saudi J Kidney Dis Transpl Source Type: research

Crescentic infection related glomerulonephritis in adult and its outcome.
Abstract The epidemiology of infection-related glomerulonephritis (IRGN) is changing in recent times both in developed and developing nations. Although published studies showed renal outcome in adult IRGN was not as benign as in children, literature regarding clinical profile and outcome of crescentic form of adult IRGN is scarce; hence, we aimed to study the clinical profile of crescentic IRGN. We conducted a retrospective observational study in patients with crescentic IRGN in adults at the Department of Nephrology, Madras medical college, Chennai between 2009 and 2014. A total of 47 patients were included with ...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Sakthirajan R, Dhanapriya J, Nagarajan M, Dineshkumar T, Balasubramaniyan T, Gopalakrishnan N Tags: Saudi J Kidney Dis Transpl Source Type: research

Who is sleeping more efficient? Patients on peritoneal dialysis or hemodialysis.
Abstract Sleep disorder, a common complaint among patients with the end-stage renal disease can affect most aspects of life. Therefore, we aimed to compare sleep quality of patients with peritoneal dialysis (PD) and hemodialysis (HD). This cross-sectional study was conducted on patients on dialysis who were referred to three major centers of Shiraz. The Pittsburgh Sleep Quality Index (PSQI) was used to compare sleep quality between patients on PD and HD. We also assessed some baseline characteristics to find out if they were independent predictors of sleep quality. Spearman correlation coefficients, one and two sa...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Malekmakan L, Tadayon T, Azadian F, Sayadi M Tags: Saudi J Kidney Dis Transpl Source Type: research

Early initiation of angiotensin-converting enzyme inhibitors in postrenal transplant period: A study from a state-run tertiary care center.
Abstract Angiotensin-converting enzyme inhibitors (ACEi) comprise a drug class, which are potent antihypertensives with renoprotective effects but are grossly underutilized in renal transplant recipients. These drugs have been reported to cause elevated potassium and creatinine levels in some renal transplant patients. There have been no reports of prospective studies on use of ACEi in renal transplant patients in the early post-transplant period. The purpose of this study is to assess the safety of an ACEi, when started in the early post-transplant period. In this prospective observational study, we reviewed 78 k...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Sreeadhara CG, Narayanaswamy R, Lingaraju U, Leelavathi V, Shivaprasad SM Tags: Saudi J Kidney Dis Transpl Source Type: research

Histopathological study of nephrotic syndrome in adults: A Moroccan report.
Abstract The reported causes of nephrotic syndrome (NS) varies between different countries. In this retrospective study, we aimed to evaluate the underlying causes of NS in adult patients who underwent renal biopsy in a region of Morocco and we also determined the distribution of histopathological diagnoses with regard to the age subgroups and genders from January 2007 to December 2016. Patients were divided into four groups according to age at the time of renal biopsy. A total of the 257 patients with NS were included in this study. The mean age of the patients was 40.9 ± 16.7 years; male gender was prepon...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Zajjari Y, Aatif T, Kawtar H, Benbria S, Montasser D, El Kabbaj D Tags: Saudi J Kidney Dis Transpl Source Type: research

Albuminuria status and patterns of dyslipidemia among type 2 diabetes black patients managed at a tertiary health-care hospital: A Post hoc analysis.
Abstract Cardiovascular disease (CVD) risk in type 2 diabetes mellitus (T2DM) increases with the development of albuminuria and is related in part to dyslipidemia. The present analysis assessed lipid profile and patterns of dyslipidemia in T2DM patients according to albuminuria status. This was a post hoc analysis of data from 181 T2DM patients seen at a tertiary health-care hospital and enrolled in a cross-sectional study of albuminuria status. Abnormal albuminuria was defined as microalbuminuria [albumin to creatinine ratio (ACR) 30-299.9 mg/g] or macro-albuminuria (ACR ≥300 mg/g). Atherogenic dyslipidemia wa...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Kajingulu FM, Lepira FB, Mbutiwi FI, Makulo JR, Sumaili EK, Bukabau JB, Mokoli VM, Longo AL, Nseka NM Tags: Saudi J Kidney Dis Transpl Source Type: research

A six-year survey of the spectrum of renal disorders on native kidney biopsy results in Central Iran and a review of literature.
In this study, we aimed to determine the prevalence of renal biopsy disorders in Iran and compare it with that of other studies in the world. This cross-sectional study evaluated consecutive native kidney biopsies performed in four centers in Isfahan, Iran, from 2009 to 2014. We also reviewed other relevant studies in Iran and the world. Overall, 1547 renal biopsies were reviewed; 493 cases were excluded (transplant or re-biopsy cases) and 1054 cases (43.3% female) were included in our study with a mean (±standard deviation) age of 33.1 (±18.5) years. The first three most prevalent diagnoses were focal and se...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Daneshpajouhnejad P, Behzadi E, Amoushahi S, Aghabozorgi A, Farmani A, Hosseini SM, Taheri D Tags: Saudi J Kidney Dis Transpl Source Type: research

Knowledge and attitude toward organ donation among health-care professionals in a rural town in India.
Abstract Organ shortage is the greatest challenge facing the field of organ transplantation today. We aimed to study the attitude and knowledge toward organ donation among health-care professionals (HCPs) in rural India. The study was conducted in a rural town in Konkan region of Maharashtra in India. A questionnaire testing knowledge and attitude about various aspects of organ donation was distributed to HCPs. One hundred percent of the respondents were aware about organ donation. Nearly 40.6% and 21.9% believed that a healthy person and a cardiac dead person can be donors, respectively. Fifty percent believed th...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Bharambe VK, Arole VU, Puranam V, Kulkarni PP, Kulkarni PS Tags: Saudi J Kidney Dis Transpl Source Type: research

Primary IgA nephropathy in the Kashmiri population.
Abstract IgA nephropathy (IgAN) remains one of the most common glomerular lesions, which has a striking geographic distribution and is the most common form of primary glomerular disease in Asia. However, the exact prevalence or clinicopathological spectrum of IgAN in India is not well documented. This retrospective study analyzed the presentation in 126 patients of primary IgAN out of 298 native kidney biopsies (42.28%) performed over a period of three years (2013-2015). The patients were followed up for three months. This is the second highest prevalence recorded in the world after Japan. Among the clinical featu...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Chowdry AM, Najar MS, Mir MM, Azad H, Rashid RA, Ashraf BM, Ahmed BK, Maqsood WM, Ahmed WI Tags: Saudi J Kidney Dis Transpl Source Type: research

Pediatric acute kidney injury in North India: A prospective hospital-based study.
Abstract The conducted study aimed to determine the incidence and clinical profile of acute kidney injury (AKI) in hospitalized patients using the AKI Network (AKIN) criteria. This prospective observational study was conducted at the Pediatric ward and pediatric Intensive Care Unit of a tertiary level teaching hospital in North India. The participants were 763 consecutive patients aged three months to 12 years from January 2014 to October 2015 and were assessed for eligibility. Of these, 163 patients were excluded from the study. Main outcome measure was incidence of AKI based on the AKIN criteria. Factors associa...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Nawaz S, Afzal K Tags: Saudi J Kidney Dis Transpl Source Type: research

A case report of successful renal transplantation in an ABO incompatible patient with a preformed donor-specific antibody and negative CDC human leukocyte antigens crossmatch.
Abstract ABO incompatibility and preformed antibodies against the human leukocyte antigen (HLA) are two impermissible barriers to a successful renal transplantation, especially in highly sensitized patient population. With the availability of effective desensitization regimens, good patient and graft outcomes have been reported. As transfusion medicine specialists we report our experience, where patient presented with dual histocompatibility barriers i.e. ABO incompatibility along with preformed donor-specific antibodies (DSA) and negative complement dependent lymphocytotoxicity (CDC) HLA crossmatch. The desensiti...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Chowdhry M, Makroo RN, Kakkar B, Jasuja S, Sagar G, Thakur Y Tags: Saudi J Kidney Dis Transpl Source Type: research

Recurrence of membranous nephropathy three weeks' postrenal transplant: A surprise in store.
Abstract Membranous nephropathy (MN) may occur in the transplanted kidney, either as recurrent disease in patients who had MN as the cause of end-stage renal disease (ESRD) in the native kidney or de novo, in patients who had another cause of ESRD initially. The reported incidence of recurrent MN ranges between 10% and 45%. Clinical manifestations of recurrent MN are typically observed 13-15 months after transplantation, although they may be observed much earlier (within weeks). Our patient had a recurrence in three weeks. Recurrent disease can lead to loss of the allograft. PMID: 29970749 [PubMed - in proces...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Kumar AN, Murlidharan P, Patil S, Balan S, Ramdas P Tags: Saudi J Kidney Dis Transpl Source Type: research

Genitourinary melioidosis in a Bangladeshi farmer with IgA nephropathy complicated by steroid-induced diabetes mellitus.
Abstract Melioidosis is an emerging infectious disease in many countries including Bangladesh. Genitourinary infection due to Burkholderia pseudomallei is a well-recognized manifestation although less commonly reported in Asia than Australia. Here, we report case history of a 38-year-old Bangladeshi farmer, diagnosed with IgA nephropathy and on oral prednisolone, who presented with features of urinary tract infection. Diagnostic workup confirmed genitourinary infection due to B. pseudomallei and diabetes mellitus. He was treated with ceftazidime followed by the combination of co-trimoxazole and doxycycline. After ...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Rahim MA, Samad T, Ananna MA, Ul Haque WMM Tags: Saudi J Kidney Dis Transpl Source Type: research

Should antiviral monotherapy with nucleotide analogs be the primary treatment option for focal segmental glomerulosclerosis-related nephrotic syndrome in chronic hepatitis B infection?
We describe a case of nephrotic syndrome due to secondary tip variant FSGS in a patient with chronic HBV infection who went into complete remission with antiviral therapy alone and present an argument for the use of oral antiviral agents as the primary treatment option for FSGS-related nephrotic syndrome in chronic HBV-infected patients without progressive liver disease. PMID: 29970751 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Javaid MM, Khatri P, Subramanian S Tags: Saudi J Kidney Dis Transpl Source Type: research

Multiple tuberculomas invading the central nervous system as a paradoxical reaction in a kidney transplantation recipient.
We report a paradoxical reaction of spinal intramedullary and multiple intracranial tuberculomas in a patient with miliary TB who had received appropriate treatment for more than two weeks. PMID: 29970752 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Kim Y, Kim SP, Han S Tags: Saudi J Kidney Dis Transpl Source Type: research

A patient with polycystic kidney disease, hepatic cysts and atrial myxoma.
Abstract With the development of renal replacement therapy, cardiovascular complications have become the major cause of death in patients with polycystic kidney disease (PKD). Atrial myxoma is a cardiac abnormality that has been rarely reported with PKD. The presence of atrial myxomas is not free of complication as it can cause cardiac outflow obstruction and embolic manifestations ending up in death. Here, we report a case of a 44-year-old female who presented with PKD associated with atrial myxoma. A 44-year-old female presented to the emergency department unconscious with a history of sudden onset of dizziness ...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Alfishawy M, Ali H, Daoud A Tags: Saudi J Kidney Dis Transpl Source Type: research

Poststreptococcal glomerulonephritis with atypical hemolytic uremic syndrome: An unusual presentation.
Abstract A 14-year-old female presented with oliguric dialysis requiring kidney injury due to acute poststreptococcal glomerulonephritis (PSGN) with hypertension strongly suggestive of atypical hemolytic uremic syndrome (aHUS) with microangiopathic hemolytic anemia and elevated factor H antibody levels. Renal biopsy revealed crescentic glomerulonephritis with typical subepithelial, intramembranous and mesangial electron-dense deposits (humps) on electron microscopy. She was treated with glucocorticoids following which she recovered, remained dialysis free and her Factor H antibody levels and depressed complement 3...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Parekh M, Konnur A, Gang S Tags: Saudi J Kidney Dis Transpl Source Type: research

Acquired cystic kidney disease and renal tumor.
We report a case highlighting the importance of screening for renal malignancy in renal transplant patients. PMID: 29970755 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Chunduri S, Desai T, Vachharajani TJ Tags: Saudi J Kidney Dis Transpl Source Type: research

Anemia and ferritin in hemodialysis: A new insight for evaluation of managing system.
PMID: 29970756 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Malaki M Tags: Saudi J Kidney Dis Transpl Source Type: research

Kidney cysticercosis, cysticercosis related kidney disease and cysticercosis in patients with underlying renal problem: A Rare but important tropical renal infection.
PMID: 29970757 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Joob B, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Filgrastim-related acute kidney injury in a male renal transplant recipient.
PMID: 29970758 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Anupama PH, Abraham G, Koshy P, Mathew M, George DS Tags: Saudi J Kidney Dis Transpl Source Type: research

Acute kidney injury due to mothball poisoning: Indian pediatric cases.
PMID: 29970759 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Joob B, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Having rs1042636C677T calcium-sensing receptor polymorphism: Increased or decreased risk for nephrolithiasis?
PMID: 29970760 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Yasri S, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Comparison of anemia and ferritin level between patients on hemodialysis and peritoneal dialysis.
PMID: 29970761 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Malaki M Tags: Saudi J Kidney Dis Transpl Source Type: research

Interleukin-6 -174G/C polymorphism and end-stage renal disease: Is there any role?
PMID: 29970762 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Srriwijitalai W, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Transplant recipients with cytomegalovirus and BK polyomavirus coinfection nephropathy.
PMID: 29970763 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2018 Category: Urology & Nephrology Authors: Yasri S, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

What we do and do not know about women and kidney diseases; Questions unanswered and answers unquestioned: Reflection on World Kidney Day and International Woman's Day.
Abstract Chronic Kidney Disease affects approximately 10% of the world's adult population: it is within the top 20 causes of death worldwide, and its impact on patients and their families can be devastating. World Kidney Day and International Women's Day in 2018 coincide, thus offering an opportunity to reflect on the importance of women's health and specifically their kidney health, on the community, and the next generations, as well as to strive to be more curious about the unique aspects of kidney disease in women so that we may apply those learnings more broadly. Girls and women, who make up approximately 50% ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2018 Category: Urology & Nephrology Authors: Piccoli GB, Alrukhaimi M, Liu ZH, Zakharova E, Levin A Tags: Saudi J Kidney Dis Transpl Source Type: research

Atypical hemolytic uremic syndrome: Laboratory characteristics, complement-amplifying conditions, renal biopsy, and genetic mutations.
This article focuses on the role of four distinct aspects of aHUS that assist clinicians in making an accurate diagnosis of aHUS. First, because of the lack of a single specific laboratory test for aHUS, other forms of thrombotic microangiopathies such as thrombotic thrombocytopenic purpura and Shiga toxin-associated HUS must be excluded to successfully establish the diagnosis of aHUS. Second, application of the knowledge of complement-amplifying conditions is critically important in making an accurate diagnosis. Third, when available, a renal biopsy can reveal changes consistent with thrombotic microangiopathy. Fourth, ge...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2018 Category: Urology & Nephrology Authors: Hossain MA, Cheema A, Kalathil S, Bajwa R, Costanzo EJ, Cosentino J, Cheng J, Vachharajani T, Asif A Tags: Saudi J Kidney Dis Transpl Source Type: research

Association of brucellosis with renal tubular and glomerular damage in children in Turkey.
Abstract Brucellosis is a multisystem disease that may present with a broad spectrum of clinical manifestations. Until now, no studies have been performed on renal tubular disorders in patients with brucellosis. The present study aims to investigate renal tubular disorders in patients with brucellosis. This prospective case-control study includes a total of 31 brucellosis patients (Group 1) and 30 healthy controls (Group 2) matched for age and sex. Renal tubular functions of children who were diagnosed as having brucellosis in outpatient pediatric clinics were evaluated. First-morning urine samples were collected ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2018 Category: Urology & Nephrology Authors: Conkar S, Kosker M, Cevik S, Ay M Tags: Saudi J Kidney Dis Transpl Source Type: research

Evaluation of serum soluble urokinase plasminogen activator receptor as a marker for steroid-responsiveness in children with primary nephrotic syndrome.
Abstract Nephrotic syndrome (NS) is the most common primary glomerular disease among children. It runs a relapsing course involving prolonged periods of treatment with corticosteroids and other immunosuppressive medications. Soluble urokinase plasminogen activator receptor (suPAR) has been regarded as an inflammatory as well as a permeability factor. The aim of our study was to evaluate serum suPAR levels in children with NS and its relation to steroid responsiveness. Our study was carried out on 75 children who were already diagnosed as having NS; they were classified into three groups (steroid sensitive, steroid...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2018 Category: Urology & Nephrology Authors: Mousa SO, Saleh SM, Aly HM, Amin MH Tags: Saudi J Kidney Dis Transpl Source Type: research

Atypical hemolytic uremic syndrome: A monocentric adult Tunisian study and review of literature.
Abstract Atypical hemolytic uremic syndrome (aHUS) is characterized by microvascular thrombosis resulting in thrombocytopenia, hemolytic anemia, and multiorgan dysfunction. It is associated with genetic or acquired disorders of regulatory components of the complement system. For our study, we collected data from 16 patients diagnosed with aHUS between January 2010 and January 2014. The mean age was 33.6 years. The female-to-male ratio was 3. The median follow-up duration was 27 ± 3.5 months. The most common clinical presentation was hypertension. Renal involvement was noted in all cases. Ten patients had ex...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2018 Category: Urology & Nephrology Authors: Kherder-Elfekih R, Hajji M, Fatma LB, Jebali H, Mami I, Smaoui W, Krid M, Rais L, Beji S, Zouaghi K, Sellami-Kallel M Tags: Saudi J Kidney Dis Transpl Source Type: research

ADAMTS-13 level in children with severe diarrhea-associated hemolytic uremic syndrome: Unmasking new association.
This study aimed to evaluate the ADAMTS-13 level in severe typical HUS. This prospective case-control study was carried out in the Pediatric Nephrology Unit and Clinical Pathology Department, Faculty of Medicine, Zagazig University from February 2013 to February 2014. The study included 15 consecutive children with typical HUS as well as 15 healthy children as a control group. Routine laboratory investigations were performed. Assessment of serum ADAMTS-13 level was performed using the Quantikine human ADAMTS-13 ELISA kit. Data were analyzed using Statistical Package for Social Sciences version 16. Nonparametric values were...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2018 Category: Urology & Nephrology Authors: Khalifa NA, Gawish HH, Khalifa NA, Tawfeek DM, Morsy SM Tags: Saudi J Kidney Dis Transpl Source Type: research

Scoring systems and outcome of chronic kidney disease patients admitted in intensive care units.
This study assessed the outcome of CKD patients admitted to the ICU and evaluated prediction of 30-day mortality using the Acute Physiology and Chronic Health Evaluation (APACHE II), Simplified Acute Physiology Score (SAPS II), and Sequential Organ Failure Assessment (SOFA) score. One hundred consecutive CKD patients admitted to the ICU at a tertiary care hospital, Ahmedabad between 2011 and 2013 were included prospectively. Data on demographics, indication for admission, cause of CKD, use of vasoactive drugs and mechanical ventilation (MV), mode of renal replacement therapy (RRT), and 30-day mortality were recorded. The A...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2018 Category: Urology & Nephrology Authors: Goswami J, Balwani MR, Kute V, Gumber M, Patel M, Godhani U Tags: Saudi J Kidney Dis Transpl Source Type: research

Impact of body mass index on progression of primary immunoglobulin a nephropathy.
Abstract The role of obesity in the progression of primary glomerular diseases is controversial. A few studies report overweight/obesity as a risk factor for disease progression in immunoglobulin A nephropathy (IgAN), and the real impact of it still remains unclear. The aim of this study was to elucidate the effect of body mass index (BMI) on disease progression and proteinuria in patients with IgAN in Indian population. A cohort of biopsy-proven primary IgAN patients diagnosed between March 2010 and February 2015 who had a follow-up for a minimum of 12 months were included in the study. We defined two groups of p...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2018 Category: Urology & Nephrology Authors: Nagaraju SP, Rangaswamy D, Mareddy AS, Prasad S, Kaza S, Shenoy S, Saraf K, Attur RP, Parthasarathy R, Kosuru S, Mateti UV, Guddattu V, Koulmane Laxminarayana SL Tags: Saudi J Kidney Dis Transpl Source Type: research

Complementary bodybuilding: A potential risk for permanent kidney disease.
We report our experience of renal disease associated with bodybuilders who had been on high-protein diet, anabolic androgenic steroids (AASs), and growth hormone (GH) for years. A total of 22 adult males who volunteered information about use of high protein diet and AAS or GH were seen over a six-year period with renal disease. Kidney biopsy revealed focal segmental glomerulosclerosis (FSGS) in eight, nephroangiosclerosis in four, chronic interstitial nephritis in three, acute interstitial nephritis in two, nephrocalcinosis with chronic interstitial nephritis in two, and single patients with membranous glomerulopathy, cres...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2018 Category: Urology & Nephrology Authors: El-Reshaid W, El-Reshaid K, Al-Bader S, Ramadan A, Madda JP Tags: Saudi J Kidney Dis Transpl Source Type: research

Prevalence of malnutrition in hemodialysis patients: A single-center study in Palestine.
Abstract Only a few studies have been published on the nutritional status of hemodialysis (HD) patients in Arab countries. The aim of this study was to determine the nutritional status and prevalence of malnutrition and its predictors among HD patients at An-Najah National University Hospital, Nablus, Palestine. A cross-sectional study was carried out on HD patients in this hospital. Seven-Point Subjective Global Assessment (7-point SGA) was used to assess the nutritional state of HD patients. Biochemical tests were obtained during the study period from medical files of the studied patients. A total of 106 HD pati...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2018 Category: Urology & Nephrology Authors: Rezeq HA, Khdair LN, Hamdan ZI, Sweileh WM Tags: Saudi J Kidney Dis Transpl Source Type: research