Primary hyperoxaluria in infants.
Abstract The infantile form of primary hyperoxaluria type-1 (PH-1) is characterized by a rapid progression to the end-stage renal disease (ESRD) due to both increased oxalate load and reduced glomerular filtration rate. In the literature, data on this form are limited. The purpose of this study is to analyze retrospectively the clinical, biological, and radiological features of children who were diagnosed with PH-1 during the 1styear of life. We reviewed the records of all children with PH-1 diagnosed and followed-up at our department between January 1995 and December 2013. Among them, only infants younger than 12...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Jellouli M, Ferjani M, Abidi K, Zarrouk C, Naija O, Abdelmoula J, Gargah T Tags: Saudi J Kidney Dis Transpl Source Type: research

Comparison between doppler ultrasound resistive index, serum creatinine, and histopathologic changes in patients with kidney transplant dysfunction in early posttransplantation period: A single center study with review of literature.
Abstract To determine the relationship between resistive index (RI) measured by Doppler ultrasound, serum creatinine (SCr), and histopathological changes on biopsy during kidney trans- plant dysfunction in early postoperative period, we studied 47 kidney transplant patients; 61% of the patients had acute transplant rejection, 19% had acute tubular necrosis, 4% had calcineurin inhibitor toxicity, 11% had normal morphology in biopsy, and 5% had changes compatible with pyelonephritis. None of the study patients had interstitial fibrosis or tubular atrophy on biopsy. We found that the sensitivity and specificity of RI...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Patel KN, Patel NA, Gandhi SP Tags: Saudi J Kidney Dis Transpl Source Type: research

Serum sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis of patients with membranous nephropathy and focal and segmental glomerulosclerosis.
This study was conducted to analyze proteins with different MWs in patients with MN and FSGS and to compare the two groups with regard to their protein profile. This was a comparative, experimental study performed from June 2013 to July 2014 in the Department of Nephrology, Sir Sunderlal Hospital, Banaras Hindu University, Varanasi. Twenty-three histologically diagnosed cases of primary MN and 25 cases of FSGS were included in the study. Patients were categorized as having mild, moderate, and severe proteinuria with 24 h urinary protein levels of
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Pant P, Singh RG, Usha, Singh SK, Singh VP, Doley PK, Sivasankar M Tags: Saudi J Kidney Dis Transpl Source Type: research

The relationship between concentrations of magnesium and oxidized low-density lipoprotein and Beta2-microglobulin in the serum of patients on the end-stage of renal disease.
Abstract The end-stage of renal disease is associated with increased oxidative stress and oxidative modification of low-density lipoproteins (LDLs). Beta2 microglobulin (beta2M) is accumulated in the serum of dialysis patients. Magnesium (Mg) plays a protective role in the development of oxidative stress in healthy subjects. We studied the relationship between concentrations of magnesium and oxidized LDL (ox-LDL) and beta2M in the serum of patients on the end stage of renal disease. In 96 patients on on-line- predilution hemodiafiltration, beta2M and intact parathormone were measured by radioimmunoassays. High-sen...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Raikou VD, Kyriaki D Tags: Saudi J Kidney Dis Transpl Source Type: research

Hemodialysis safety: Evaluation of clinical practice.
Abstract Hemodialysis (HD) safety has become a clinical priority; therefore, the use of checklists for making the dialysis session safe is now widely adopted. The aim of our study was to assess different shortcomings in the clinical practice of nurses working in different Moroccan dialysis centers and to discuss the interest of using such checklists. This cross-sectional study was performed in 13 chronic HD centers. Clinical practice of nurses was evaluated through checklists used in European outpatient dialysis units. We noted several deficiencies mainly related to the clinical evaluation of dialysis patients and...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Fadili W, Adnouni A, Laouad I Tags: Saudi J Kidney Dis Transpl Source Type: research

Clinicopathological correlations of renal pathology: A single center experience.
In conclusion, GN was the most common pathology in this study, FSGS and MPGN were the most common patterns in primary GN. PMID: 27215250 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Ismail MI, Lakouz K, Abdelbary E Tags: Saudi J Kidney Dis Transpl Source Type: research

Characteristics and outcome of living kidney donors after donation: A report from Cote d'Ivoire.
Abstract Kidney transplantation from living kidney donors (LKDs) because of its good results represents a good option for the treatment of patients with the end-stage renal disease. Kidney donation is a relatively safe procedure according to several studies. We conducted this cross-sectional study in order to describe the demographic, clinical, and renal outcome of LKD in Cτte d'Ivoire. From March to November 2014, LKD residing in Cτte d'Ivoire at the time of investigation and having donated the kidney more than one year ago were considered for the study. They were evaluated through a questionnaire. Of the...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Lagou DA, Ackoundou-N'guessan KC, Njapom TL, Sekongo YM, Guei CM, Tia MW, Gnionsahe DA Tags: Saudi J Kidney Dis Transpl Source Type: research

A study of outcome and complications associated with temporary hemodialysis catheters in a Nigerian dialysis unit.
Abstract Hemodialysis (HD) catheters are commonly used as temporary vascular access in patients with kidney failure who require immediate HD. The use of these catheters is limited by complications such as infections, thrombosis resulting in poor blood flow. We studied the complications and outcomes of nontunneled catheters used for vascular access in our dialysis unit. The records of all patients, with renal failure who were dialyzed over a two-year period and had a double lumen nontunneled catheter inserted, were retrieved. Catheter insertion was carried out under ultrasound guidance using the modified Seldinger ...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Amira CO, Bello BT, Braimoh RW Tags: Saudi J Kidney Dis Transpl Source Type: research

Histopathological types in adult nephrotic syndrome.
Abstract In Bangladesh, there are very few studies about biopsy proven adult Nephrotic syndrome (NS) with histological types and their clinical findings. To determine the histological types of glomerulonephritis (GN) in adult NS and correlate them with the clinical presentations and biochemical parameters, we studied 100 biopsies in 87 patients who underwent ultrasonography- guided renal biopsy in Rangpur Medical College and Hospital from July 2010 to June 2012. The mean age of the patients was 32.8 ± 13.2 years; male was preponderance (72.4%) and most of the patients (67.8%) came from rural areas. Membrano...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Yusuf MG, Das BB, Shaha AC, Hossain MZ Tags: Saudi J Kidney Dis Transpl Source Type: research

Severe hemorrhage complicating early transplant nephrectomy due to sepsis.
We present a case of severe bleeding from the external iliac artery secondary to a pelvic abscess following renal transplantation and transplant nephrectomy. A 73-year-old man received an extended criteria donor organ from a 49-year-old person who died from systemic sepsis. The patient bled from the Carrel's patch while awaiting a computed tomographic scan- guided drainage of an infected peritransplant collection. At exploration, a nonviable allograft surrounded by about 1 L of thick pus was removed. Bleeding from a 2 mm hole in the Carrel's patch was repaired by prolene suture as the external iliac vessels could not be mo...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Akoh JA, Rana T Tags: Saudi J Kidney Dis Transpl Source Type: research

Nonocclusive mesenteric ischemia after renal transplantation: A case report and literature review.
We describe a 51- year-old man with end-stage renal disease who developed intestinal ischemia and infarction due to NOMI three days after deceased donor kidney transplantation, which was managed success- fully and his renal graft function was saved. To the best of our knowledge, this is one of the few cases of NOMI occurring after renal transplantation reported in the literature. PMID: 27215255 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Tavakkoli M, Mahdavi-Zafarghandi R, Ghoreifi A, Khooei A Tags: Saudi J Kidney Dis Transpl Source Type: research

Renal manifestations of human brucellosis: First report of minimal change disease.
Abstract Human brucellosis is considered a great example of the complexity of clinical manifestations possibly affecting multiple organs or systems. Renal manifestations of human brucellosis have been documented in few case reports and one case series. Herein, we present a case of Nephrotic syndrome (NS) due to minimal change disease in the course of acute brucellosis. A 53-year-old male farmer was admitted to our department with acute brucellosis and NS. Renal biopsy revealed minimal change disease. Combined treatment with prednisone (1 mg/kg), rifampicin (600 mg/day), and doxycycline (200 mg/day) was initiated. ...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Sabanis N, Gavriilaki E, Paschou E, Tsotsiou E, Kalaitzoglou A, Kavlakoudis C, Vasileiou S Tags: Saudi J Kidney Dis Transpl Source Type: research

Baclofen-induced neurotoxicity in a patient with end-stage renal disease.
Abstract Baclofen, predominantly excreted by the kidneys is accumulated in patients with renal insufficiency leading to the central nervous system toxicity. Here the author reports a patient with end-stage renal disease on maintenance hemodialysis (HD) who developed drowsiness and became unresponsive within a day after taking single 10 mg dose of baclofen. Patient improved completely after two sessions of HD. PMID: 27215257 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Radhakrishnan H Tags: Saudi J Kidney Dis Transpl Source Type: research

Infantile nephropathic cystinosis with incomplete fanconi syndrome, hypothyroidism, hydro-uretero-nephrosis, and megacystis.
We describe the clinical features in a four and a half-year-old Indian boy with infantile nephropathic cystinosis that presented with the incomplete Fanconi syndrome, hydro-uretero-nephrosis with megacystis, and hypothyroidism. PMID: 27215258 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: More V, Shanbag P Tags: Saudi J Kidney Dis Transpl Source Type: research

Anti-neutrophil cytoplasmic antibody negative crescentic paucimmune glomerulonephritis in a case of scleroderma with systemic lupus erythematosus overlap.
We report a case in which the renal manifestation in such a situation was of a focal necrotising pauci-immune glomerulonephritis with crescents, anti-neutrophil cytoplasmic antibody negative. To the best of our knowledge, such manifestations have not been described before. Renal dysfunction in a normotensive setting in such a case should direct one towards evaluation for other causes and should prompt a kidney biopsy. This would be valuable in delineating the pathological process in the kidney and would help in guiding therapy. PMID: 27215259 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Disease...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Tewari R, Badwal S, Kumar A, Subramaniam S, Nijhawan VS, Srinivas V Tags: Saudi J Kidney Dis Transpl Source Type: research

Primary hyperoxaluria in an adult male: A rare cause of end-stage kidney disease yet potentially fatal if misdiagnosed.
Abstract Primary hyperoxaluria is an autosomal recessive disorder due to a deficiency in the activity of the peroxisomal hepatic enzyme alanine-glyoxylate aminotransferase. It is a common cause of urolithiasis and end-stage kidney disease in children contrary to the adult phenotypic presentation which is considered a mild disorder with occasional urolithiasis. In this case report, we describe a 25-year-old man who presented with advanced and irreversible kidney failure within three months following strenuous physical training in the police academy. He had nephrocalcinosis and stones in one kidney. Diagnosis was co...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: El-Reshaid K, Al-Bader D, Madda JP Tags: Saudi J Kidney Dis Transpl Source Type: research

An unusual presentation of juvenile lupus nephritis.
Abstract The incidence of juvenile lupus varies widely ranging between 4 and 250 per 100,000 population. Most common organ involvement in juvenile lupus is kidney. Neurological, cutaneous and hematological involvements are also involved. Skeletal muscle involvement in the form of myositis is rare. Myositis as presenting manifestation in juvenile lupus is also unusual. Herein, we report one such case wherein myositis preceded the onset of lupus nephritis. PMID: 27215261 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Bottu M, Yadla M, Burri S, Uppin M Tags: Saudi J Kidney Dis Transpl Source Type: research

Report of a kidney recipient with inguinal herniation of the transplant ureter.
PMID: 27215262 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Soleymanian T, Kalantarian T, Radmard A Tags: Saudi J Kidney Dis Transpl Source Type: research

Remarks about the study on evaluation of thyroid hormone levels in chronic kidney disease patients.
PMID: 27215263 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Al-Mendalawi MD Tags: Saudi J Kidney Dis Transpl Source Type: research

Remarks about the study of eosinophilic cystitis and idiopathic hyper-eosinophilic syndrome in a eight-year-old girl.
PMID: 27215264 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Al-Mendalawi MD Tags: Saudi J Kidney Dis Transpl Source Type: research

Restless leg syndrome and its treatment.
PMID: 27215265 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Shubhakaran K Tags: Saudi J Kidney Dis Transpl Source Type: research

Remarks about the study on immunoglobulin G4-related disease: Two case reports and review of the recent literature.
PMID: 27215266 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Adwan MH Tags: Saudi J Kidney Dis Transpl Source Type: research

Adrenal insufficiency in snake envenomation: Another piece of puzzle?
PMID: 27215267 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Senthilkumaran S, Jena NN, Sandeep GB, Thirumalaikolundusubramanian P Tags: Saudi J Kidney Dis Transpl Source Type: research

Remarks about the study of an unusual presentation of venous thrombosis in a child with idiopathic membranous nephropathy.
PMID: 27215268 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Al-Mendalawi MD Tags: Saudi J Kidney Dis Transpl Source Type: research

Effects of type of body weight type on acute kidney injury diagnosis.
PMID: 27215269 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Ratanapo S Tags: Saudi J Kidney Dis Transpl Source Type: research

Averting the legacy of kidney disease - Focus on childhood.
Abstract World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD) in childhood differs from that in adults, as the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease in the setting of diabetes being relatively uncommon. In addition, many children with acute kidney injury will ultimately develop sequelae that may lead to hypertension and CKD in later childhood or in adult life. Children born early or who are small-for ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Ingelfinger JR, Kalantar-Zadeh K, Schaefer F, World Kidney Day Steering Committee Tags: Saudi J Kidney Dis Transpl Source Type: research

Pregnancy after renal transplantation: Effects on mother, child, and renal graft function.
Abstract The aim of this study was to report our experience of pregnancy in renal transplant (RT) patients and its medium and long-term effects on the renal graft as well as the maternal fetal complications. We studied 21 pregnancies in 12 RT patients with mean age of 29.9 ± 5.3 years. The mean duration of RT to 1 st pregnancy was 42 (21-68.5) months and the median follow-up period was 112.5 (138-165) months. The pregnancy was planned in 28.6% of the cases. At the time of the diagnosis of the pregnancy, all the patients were maintained on corticosteroids and cyclosporine, 14.3% of the patients were on mycop...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: El Houssni S, Sabri S, Benamar L, Ouzeddoun N, Bayahia R, Rhou H Tags: Saudi J Kidney Dis Transpl Source Type: research

Serum magnesium level and vascular stiffness in children with chronic kidney disease on regular hemodialysis.
In this study, we aimed to assess the relationship between serum Mg levels and vascular stiffness in children with CKD on regular hemodialysis (HD). The study included 25 children with CKD on regular HD in our center; the study included also 25 healthy children age-and sex-matched as a control group. Serum Mg levels were measured, and Doppler ultrasound assessment of the intima-media thickness (IMT) and the peak systolic velocities (PSVs) of the main arteries including the (aorta, carotid, and femoral) arteries were recorded in the study patients. There were significantly lower serum Mg levels in children on regular HD tha...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Zaher MM, Abdel-Salam M, Abdel-Salam R, Sabour R, Morsy AA, Gamal D Tags: Saudi J Kidney Dis Transpl Source Type: research

Blood pressure measurement in hemodialysis: The importance of the measurement technique.
es RM Abstract Systemic arterial hypertension contributes to the high cardiovascular morbidity in hemodialysis (HD) patients, but the accuracy of blood pressure (BP) measurement in this population has not been well studied. To evaluate the agreement between BP measurement using the routine measurement technique (usual method) and the technique recommended by the VII Joint (standard method). This cross-sectional study enrolled 124 patients in a single center who had undergone dialysis for more than three months and were 18 years of age or older. The BP was verified at the start of dialysis by the nursing team (usua...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Kubrusly M, de Oliveira CM, Silva RP, Pinheiro MA, Rocha MB, Magalhães RM Tags: Saudi J Kidney Dis Transpl Source Type: research

Influence of nutritional education on hemodialysis patients' knowledge and quality of life.
Abstract To determine the effects of educational instructions on hemodialysis patients' knowledge and quality of life (QOL), we studied 99 patients randomly assigned to control and experimental groups after participation in a pretest exam. The two groups were not significantly different in terms of demographic composition. The instrument used in this study was a questionnaire regarding patients' knowledge and the standard questionnaire to assess QOL for end-stage renal disease (ESRD) patients. Then, intervention (nutritional education) was conducted in the experimental group lasting for 12 weeks. After 16 weeks, a...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Ebrahimi H, Sadeghi M, Amanpour F, Dadgari A Tags: Saudi J Kidney Dis Transpl Source Type: research

Effect of Vitamin B 12 supplementation on serum homocysteine in patients undergoing hemodialysis: A randomized controlled trial.
Abstract Clinical studies have shown that hyper-homocysteinemia is a potent independent risk factor for cardiovascular diseases, and many different methods have been investigated for lowering it in hemodialysis (HD) patients. Our study investigated the effect of Vitamin B 12 supplementation on serum homocysteine levels in these patients. This randomized trial was conducted on 140 HD patients. They were randomly distributed by lottery method into two groups: intervention and control. In the intervention group, 100 μg/mL of Vitamin B 12 was intravenously injected two times a week, for eight weeks. No intervention...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Tayebi A, Biniaz V, Savari S, Ebadi A, Shermeh MS, Einollahi B, Rahimi A Tags: Saudi J Kidney Dis Transpl Source Type: research

The relationship between total mass and blood supply of parathyroid glands and their secretion of parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism.
Abstract Characteristics of parathyroid glands usually determined by ultrasonography such as its total weight or volume might be a good indicator for the induction or suppression of parathyroid hormone (PTH) secretion from these glands. In the present study, we investigated the relationship between the volume and blood supply grade of the parathyroid glands, and its PTH secretion. Study subjects included 52 consecutive patients with the secondary hyperparathyroidism undergoing maintenance hemodialysis therapy referred to dialysis wards of the Imam Khomeini and Amiralam University Hospitals in Tehran. Serum intact ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Ahmadi F, Aghajanzadeh P, Yazdi HR, Maziar S, Gatmiri SM Tags: Saudi J Kidney Dis Transpl Source Type: research

A comparison of the quality of life of the patients undergoing hemodialysis versus peritoneal dialysis and its correlation to the quality of dialysis.
In this study, we have compared the quality of life of the patients undergoing either HD or PD. This cross-sectional study was performed in the dialysis center of the Noor and Saint Ali Asghar University Hospital in Isfahan, Iran in 2012. Forty-six patients who underwent PD (28 males and 18 females) and 46 similar patients undergoing HD (26 males and 20 females) were compared. A standardized Persian version of the short form-36 (SF-36) tool was used to assess the quality of life and to assess the quality of dialysis weekly Kt/V in patients undergoing PD and single random Kt/V sampling in HD patients were assessed. Patients...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Atapour A, Nasr S, Boroujeni AM, Taheri D, Dolatkhah S Tags: Saudi J Kidney Dis Transpl Source Type: research

A modified peritoneal dialysis catheter with a new technique: Farewell to catheter migration.
Abstract To evaluate the efficacy our new, three-cuff peritoneal dialysis (PD) catheter, with the low-entry technique and to study its impact on catheter survival and mechanical and infectious complications, we prospectively used it in 36 incident PD patients and compared the results with those of conventional double-cuff PD Tenckhoff catheters with the classic approach used in 37 patients. The study was carried out at our university hospital over a period of 18 months. At the end of the study, significantly higher survival rate was observed with the use of new catheter compared with the conventional two-cuff Tenc...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Al-Hwiesh AK Tags: Saudi J Kidney Dis Transpl Source Type: research

Multinational observational study on clinical practices and therapeutic management of mineral and bone disorders in patients with chronic kidney disease stages 4, 5, and 5D: The OCEANOS study.
Abstract Our aim is to assess the current clinical practices in monitoring and treatment patterns of chronic kidney disease (CKD)-mineral bone disorder and the degree to which these practices met the kidney disease improving global outcome (KDIGO) guidelines. This was an international, multi-center, cross-sectional, observational study in adult patients diagnosed with CKD Stages 4, 5, and 5D. Patients were enrolled from Middle East, South Asia, Eurasia, and Africa; patients with estimated glomerular filtration rate ≥30 mL/min/1.73 m 2 or with any medical/surgical conditions precluding their participation were e...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Shaheen FA, Kurpad R, Al-Sayyari AA, Souqiyyeh MZ, Aljubori H, El Baz T, Kashif W, Tuganbekova S, Kabulbayev K, Jarraya F, Nafar M Tags: Saudi J Kidney Dis Transpl Source Type: research

Prognostic significance of C1q deposition in serial biopsies for predicating the long-term outcome in patients with proliferative lupus nephritis.
Abstract Lupus nephritis (LN) is characterized by a highly variable clinical course. It has been reported that histopathologic lesions are risk factors for the progression of LN. The aim of this study is to investigate the relationship among the co-deposition of C1q, clinicopathological features, and renal outcomes in patients with LN. The clinical and histological parameters were studied in patients with International Society of Nephrology/Renal Pathology Society Class III or IV LN, who underwent two kidney biopsies. The patients were divided into two groups based on the glomerular C1q deposits: C1q-positive and ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Alsuwaida A, Husain S, Al Ghonaim M, Aloudah N, Ullah A, Kfoury H Tags: Saudi J Kidney Dis Transpl Source Type: research

Utility of saliva as a sample to assess renal function and estimated glomerular filtration rate.
Abstract Diagnosis of renal diseases by assessing renal parameters in saliva. Biochemical investigations using serum form important component of monitoring patients with renal disease. Utility of saliva, in diagnosis and monitoring of patients with renal disease and for calculation of estimated glomerular filtration rate (eGFR), was studied. Sixty patients with renal disease and sixty ageand sex-matched healthy controls were studied. Urea, creatinine, sodium, potassium, uric acid, calcium, and phosphorus were measured in both serum and saliva. eGFR was calculated using salivary creatinine. Data were expressed as m...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Yajamanam N, Vinapamula KS, Sivakumar V, Bitla AR, Rao PV Tags: Saudi J Kidney Dis Transpl Source Type: research

Accuracy of GFR estimation formula in determination of glomerular filtration rate in kidney donors: Comparison with 24 h urine creatinine clearance.
Abstract To determine the accuracy of estimated glomerular filtration rate (eGFR) using the modification of diet in renal disease (MDRD), Cockcroft-Gault (CG), and chronic kidney disease epidemiology (CKD-EPI) formulas in potential kidney donors compared with 24-h urine creatinine clearance, we studied 207 potential live kidney donors in our center. There were 126 (60.9%) males and 81 (39.1%) females. Male:female ratio was 1.6:1. The age of the donors ranged from 18-58 years, with mean age of 35.30 ± 9.23 years and most of the individuals were below 40 years of age. The body mass index (BMI) was calculated ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Hafeez AR, Idrees MK, Akhtar SF Tags: Saudi J Kidney Dis Transpl Source Type: research

Restless legs syndrome in hemodialysis patients.
Abstract Restless legs syndrome (RLS) is a neurological disorder characterized by uncomfortable sensation of paresthesia in legs that subsequently causes involuntary and continuous movement of the lower limbs, especially at rest. Its prevalence in hemodialysis is more than that in the general population. Different risk factors have been suggested for RLS. We studied the prevalence and risk factors of RLS in 137 hemodialysis patients followed up at our center. The patients completed at least three months on dialysis and fulfilled four criteria for the diagnosis of RLS. We compared the patients with and without RLS,...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Rafie S, Jafari M, Azizi M, Bahadoram M, Jafari S Tags: Saudi J Kidney Dis Transpl Source Type: research

The effect of depression and anxiety on the performance status of end-stage renal disease patients undergoing hemodialysis.
Abstract Individuals who are diagnosed with end-stage renal disease (ESRD) undergo major changes in lifestyle. The present cross-sectional study was conducted to identify the relationship between patients who undergo hemodialysis (HD) and their performance status, and how it is influenced by the presence of the level of depression and anxiety. A total of 50 patients were recruited from HD centers in and around Chennai. The patients were screened using the General Health Questionnaire to screen for co-morbid psychiatric conditions. The patients were assessed for depression and anxiety, and their performance status ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Rajan EJ, Subramanian S Tags: Saudi J Kidney Dis Transpl Source Type: research

Outcome of patients with multiple myeloma and renal failure on novel regimens.
Abstract Renal involvement occurs in 20-40% of newly diagnosed multiple myeloma (MM) patients, and diagnosis of myeloma is frequently made after investigation for unexplained renal disease. This is a retrospective study between 2006 and 2013 in which 57 consecutive patients seen at the Nephrology Unit with diagnosis of MM were enrolled. MM was diagnosed for the first time because of renal dysfunction and/or proteinuria in these patients. The mean age of the patients (65% male) was 58.3 ± 12.7 years. The median baseline serum creatinine was 3.5 mg/dL (1.4-14.5). Anemia (hemoglobin 10.5 mg/dL) in 35% of patie...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Soleymanian T, Soleimani A, Musavi A, Mojtahedi K, Hamid G Tags: Saudi J Kidney Dis Transpl Source Type: research

Five years renal transplantation data: Single-center experience from Iraq.
Abstract Renal transplantation is the treatment of choice for patients with end-stage renal disease. In Iraq, renal transplantation started in 1973 and has continued until now with live donor transplantation, since deceased donor transplant program is not approved as yet. Long-term transplant data are still scarce. The aim of our study is to present data on transplantation and medical follow-up at one year and, survival analysis at one, three and five years. A total of 250 renal transplantations were performed at the Nephrology and Renal Transplantation Center, Baghdad between January 2009 and January 2014. It is ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Ali AA, Al-Saedi AJ, Al-Mudhaffer AJ, Al-Taee KH Tags: Saudi J Kidney Dis Transpl Source Type: research

Prevalence and determinants of microalbuminurea among type 2 diabetes mellitus patients, Baghdad, Iraq, 2013.
Abstract Microalbuminuria (MAU) is an early marker of diabetic nephropathy (DN), which accounts for a significant reduction in life expectancy of diabetic patients. The progression of DN from the appearance of clinical proteinuria to end stage renal failure is usually irreversible. Increased levels of urinary albumin secretion may represent a more generalized vascular damage. This is the first study conducted in Iraq to determine the prevalence and potential risk factors of MAU among Type 2 diabetes mellitus (T2DM) patients. A cross-sectional study was conducted on a systematic random sample of 224 eligible T2DM p...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Ali AA, Al Lami FH Tags: Saudi J Kidney Dis Transpl Source Type: research

Graft function and nutritional parameters in stable postrenal transplant patients.
Abstract Bioelectrical impedance analysis (BIA) is a method for the assessment of nutritional status. We studied the effect of graft function on nutritional status in postrenal 45 transplant patients with borderline to good allograft function using BIA. The patients had a mean serum creatinine of 1.42 ± 0.42 mg% and mean glomerular filtration rate (GFR) of 45.1 ± 14.1 mL/min. Based on BIA-derived GFR, the patients were divided into two groups; group 1: borderline graft function GFR
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Saxena A, Sharma RK, Gupta A Tags: Saudi J Kidney Dis Transpl Source Type: research

Identification of high-risk population and prevalence of kidney damage among asymptomatic central government employees in Delhi, India.
Abstract Chronic kidney disease (CKD) has attained epidemic proportions in India due to increased incidence of diabetes and hypertension (HTN). It was surmised that identification of only high-risk groups (HRGs) through a questionnaire would be sufficient to identify cases of kidney damage (KD). The study attempted to device a questionnaire to classify the subjects in to HRG and low-risk group (LRG) and assess the extent of early KD. The central government employees were classified into HRG and LRG based on "SCreening for Occult REnal Disease (SCORED)" and "EXTENDED" questionnaire formulated af...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Mahapatra HS, Gupta YP, Sharma N, Buxi G Tags: Saudi J Kidney Dis Transpl Source Type: research

Pattern of renal diseases in children: A developing country experience.
Abstract Spectrum of renal disease varies in different ethnic population, geographical location, and by environmental factors. The purpose of this study was to find out the clinical spectrum and occurrence of different pediatric renal diseases at a teaching hospital in the Eastern part of Nepal. All cases of renal diseases from one month to 15 years of age, attending the pediatric renal outpatient department and/or were admitted to the wards during the period of February 2012 to January 2013, were included in the study. Detailed clinical and laboratory evaluations were performed on all patients. Diseases were cate...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Yadav SP, Shah GS, Mishra OP, Baral N Tags: Saudi J Kidney Dis Transpl Source Type: research

Occurrence of double primary malignancies in an African renal transplant recipient.
Abstract A 63-year-old African male with end stage renal disease who received a renal transplantation from his daughter after successful treatment of hepatitis C virus, type 1 genotype developed metastatic Kaposi's sarcoma and subsequently adenocarcinoma of the prostate. He was successfully treated with chemotherapy and reduction of immunosuppression and switch over to rapamycin. PMID: 26997394 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Mohan P, Yuvaraj A, Abraham G, Kurien A, Abraham A, Mathew M, Saravanan S, Nair S Tags: Saudi J Kidney Dis Transpl Source Type: research

Early recurrence of proliferative glomerulonephritis with monoclonal immunoglobulin deposits in a renal allograft.
Abstract Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMIDs) is a clinico-pathologic entity, the recurrence of which in the renal allograft has only recently been described. A 55-year-old male presented with rapid deterioration of renal function. Light microscopy showed membranoproliferative glomerulonephritis with kappa light chain restriction and only one sub-class of IgG. He subsequently underwent renal transplant. Two months later, he developed acute graft dysfunction. Renal biopsy showed a recurrence of the disease. Work up for multiple myeloma was positive. Membranoproliferativ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Tewari R, Joshi K, Kumar A, Rayat CS, Iyer R, Sakhuja V, Minz M Tags: Saudi J Kidney Dis Transpl Source Type: research

Successful management of chylous ascites: A report of two cases.
We present two cases of postoperative chylous ascites, one following a bilateral nephrectomy, the other following orthotopic heart transplantation. Treatment is typically conservative with the aim to alleviate abdominal distension and reduce the flow of lymph into the mesenteric lymph nodes. Postsurgical chylous ascites has high cure rate with conservative therapy alone. Therapeutic paracentesis, diuretics, salt restriction, a high-protein, low-fat, mediumchain triglyceride diet, and parenteral nutrition are considered in chronic cases. The effects of longterm paracentesis on patients remains to be seen. In patients requir...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Alam SE, Kar SM, Kar PM Tags: Saudi J Kidney Dis Transpl Source Type: research

Cerebral venous thrombosis and secondary polycythemia in a case of nephrotic syndrome.
We report an unusual combination of both these complications in a case of nephrotic syndrome due to minimal change disease that was treated successfully. There was prompt and complete remission of nephrotic syndrome with steroid therapy, concurrent with complete resolution of polycythemia and CVT. PMID: 26997397 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2016 Category: Urology & Nephrology Authors: Nagaraju SP, Bairy M, Attur RP, Sambhaji CJ Tags: Saudi J Kidney Dis Transpl Source Type: research