Knowledge, attitudes, and practice of organ donation in Morocco: A cross-sectional survey.
Abstract In any health system, public awareness of organ donation fundamentally affects the organ transplantation programs. The aim of this study was to evaluate the knowledge and perception of the people in Morocco toward organ donation as well as to identify the reasons and determinants for refusal of organ donation. This opinion survey included a representative sample of 2000 participants in Morocco, and data related to sociodemographic characteristics, knowledge and self-opinion about organ donation, and reasons behind refusal were collected. Statistical analysis showed that 55.2% of the participants were wome...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: El Hangouche AJ, Alaika O, Rkain H, Najdi A, Errguig L, Doghmi N, Aboudrar S, Cherti M, Dakka T Tags: Saudi J Kidney Dis Transpl Source Type: research

BK Virus nephropathy in living donor renal allograft recipients: An observational study from a large transplant center in India.
Abstract BK virus is a polyoma virus which remains in latent phase in the urinary tract, particularly in the renal tubular epithelial cells. In immunosuppressed patients, it is activated and manifests as tubule-interstitial nephritis causing renal allograft dysfunction. A total of 402 patients who underwent renal allograft biopsy from 2013 to 2016 were included in this study; six patients were diagnosed to have BK virus nephropathy. Histopathology showed ground glass intra-nuclear inclusions accompanied by acute tubular injury, interstitial inflammation, and varying degree of interstitial fibrosis and tubular atro...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Gupta P, Gupta A, Bhalla AK, Malik M, Gupta A, Bhargava V, Rana DS Tags: Saudi J Kidney Dis Transpl Source Type: research

G6PD deficiency is not an uncommon cause of pigment nephropathy.
Abstract Acute kidney injury (AKI) with evidence of hemolysis is associated with tropical infections. However, pigment-induced AKI can happen with relatively uncommon genetic causes of hemolytic anemia, i.e., glucose 6-phosphate deficiency (G6PD). We share our experience of three such patients whose clinical presentation was similar to jaundice, AKI with hemolysis with suspicion of thrombotic microangiopathy. On evaluation, all had a history of usage of anti-malarial and with G6PD estimation revealing deficient status even during the episode while other tests such as Coomb's test and bone marrow biopsy was normal ...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Kaul A, Prasad P, Kumari N, Bhaduaria D, Sharma RK, Prasad N, Gupta A, Krishnani N Tags: Saudi J Kidney Dis Transpl Source Type: research

Comparison of tacrolimus and cyclosporine for immunosuppression after renal transplantation: An updated systematic review and meta-analysis.
Abstract Kidney transplantation is usually followed by immunosuppressive therapy to prevent early rejection and prolong graft survival. The calcineurin inhibitors (CNIs) represent the most commonly used agents. However, available evidence suggests the poor outcome over the long term, maybe be due to the potential nephrotoxicity associated with CNIs. Several randomized trials have compared tacrolimus (TAC) with cyclosporine, to find the optimal agent for renal transplantation; however, studies have shown conflicting results. The aim of this study was to systematically review and update the evidence for the benefits...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Azarfar A, Ravanshad Y, Mehrad-Majd H, Esmaeeli M, Aval SB, Emadzadeh M, Salehi M, Moradi A, Golsorkhi M, Khazaei MR Tags: Saudi J Kidney Dis Transpl Source Type: research

Mortality of diabetic on chronic dialysis in Tunisia.
This study aims to specify the epidemio-logical, clinical, and biological characteristics of diabetic disease, chronic kidney disease (CKD), and comorbidities at the initiation of HD and investigate factors associated with mortality during the dialysis period. We retrospectively analyzed the outcome of diabetic patients who were initiated on HD from 2007 to 2012 at the Rabta Hospital of Tunis. During the follow-up period, all morbid events and deaths were recorded. Univariate analysis and multivariate analysis were performed to identify risk factors associated with mortality in our population. The study population included...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Jebali H, Laifi M, Mami I, Khadhar M, Chirmiti M, Beji S, Rheder R, Smaoui W, Krid M, Hmida FB, Rais L, Fatma LB, Zouaghi MK Tags: Saudi J Kidney Dis Transpl Source Type: research

Urinary schistosomiasis in Boko Haram-related internally displaced Nigerian children.
Abstract We aimed to determine the prevalence of urinary schistosomiasis among internally displaced children in Maiduguri, Nigeria. Data on the children's sociodemographic characteristics and risk factors for schistosomiasis were collected, over a period of six months, using an interview-based questionnaire. Ten milliliter of urine sample was collected from each child and investigated for hematuria and ova of Schistosoma haematobium. Two hundred and thirty-eight of 385 children had urinary schistosomiasis (62.0%); of this, 125 (53.0%) were males, with a male:female ratio of 1.1:1. Urinary schistosomiasis was the m...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Yauba SM, Rabasa AI, Farouk AG, Elechi HA, Ummate I, Ibrahim BA, Ibrahim HA, Baba AS, Boda TA, Olowu WA Tags: Saudi J Kidney Dis Transpl Source Type: research

Clinicopathological profile of pediatric renal biopsies at a tertiary care hospital, Pakistan.
Abstract Renal biopsy is an important tool for the diagnosis of acute and chronic glomerular diseases in children. We aimed to analyze the spectrum of clinical indications and histopathological patterns (HPP) in children who underwent renal biopsy (RB). This is a retrospective review of case records of 108 renal biopsies carried out from January 2010 to December 2015 at the Pediatric Nephrology Department, National Institute of Child Health Karachi, Pakistan. RB was performed under Ketamine-Midazolam sedation and real-time ultrasound. Trucut or monopty biopsy gun was used. Data obtained included age, gender, clini...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Sadaf A, Khemchand MN, Fouzia L, Asia Z Tags: Saudi J Kidney Dis Transpl Source Type: research

Pattern of glomerular disease and clinicopathological correlation: A single-center study from Eastern Nepal.
Abstract The pattern of glomerular disease varies worldwide. In the absence of kidney disease/kidney biopsy registry in Nepal, the exact etiology of different forms of glomerular disease is primarily unknown in our country. We analyzed 175 cases of renal biopsies performed from September 2014 to August 2016 in Internal Medicine Ward at B.P. Koirala Institute of Health Sciences. The most common indication for renal biopsy was nephrotic syndrome (34.9%), followed by systemic lupus erythematosus (SLE) with suspected renal involvement (22.3%). Majority of patients were in the 30-60 years' bracket (57.2%), with the mea...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Subedi M, Bartaula B, Pant AR, Adhikari P, Sharma SK Tags: Saudi J Kidney Dis Transpl Source Type: research

Assessment of knowledge of chronic kidney disease among non-nephrology nurses in Akure, South-West Nigeria.
This study assessed the knowledge of non-nephrology nurses on CKD with the aim of identifying areas of knowledge gaps which will be targets for future educational programs. This was a cross-sectional descriptive study carried out among nurses in Akure, Southwest Nigeria during their mandatory continuing professional development program required for practicing license renewal. Knowledge of CKD was assessed using self-administered pretested questionnaires. P
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Adejumo OA, Akinbodewa AA, Iyawe IO, Emmanuel A, Ogungbemi O Tags: Saudi J Kidney Dis Transpl Source Type: research

Quality of hemodialysis services in a poor population, Sistan and Baluchestan province, Iran: A descriptive, prospective study.
This study aimed at investigating quality-of-care indicators among hemodialysis (HD) patients. This descriptive, prospective study was conducted on 144 HD patients in Zabol and Iranshahr dialysis centers from March 21 to December 22, 2015. Measurement indicators included hemoglobin level, dialysis adequacy, albumin level, vascular access, and calcium and phosphorus levels. The mean hemoglobin and dialysis adequacy level at baseline were 10.58 ± 1.6 g/dL and 1.09 ± 0.18, respectively. At the end of the study, 49.6% of participants achieved target hemoglobin level. However, only 18.6% of patients achieved targe...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Balouchi A, Shahdadi H, Shahkzhi A, Irandgani M, Aboo S, Bolaydehyi E, Hooti M, Lundquist CM, Shahraz S Tags: Saudi J Kidney Dis Transpl Source Type: research

Assessment of iron status in predialysis chronic kidney disease patients in a Nigerian Tertiary Hospital.
This study assessed iron status and associated factors in predialysis CKD patients in Southern Nigeria. This was a cross-sectional study that assessed and compared iron status in 100 predialysis CKD patients and 90 healthy controls. Mean age of the CKD patients was 49.39 ± 14.84 years. Iron deficiency was present in 14% of CKD patients compared to 3% of the controls (P = 0.021). Among CKD patients with ID, 11 (85.7%) had functional iron deficiency while three (14.3%) had absolute iron deficiency. Serum ferritin was significantly higher in the predialysis CKD patients (P = 0.001). There was no significant gender diff...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Iyawe IO, Adejumo OA, Iyawe LI, Oviasu EO Tags: Saudi J Kidney Dis Transpl Source Type: research

A review of the epidemiology of chronic kidney disease in Pakistan: A global and regional perspective.
Abstract Both the incidence and prevalence of chronic kidney disease (CKD) are rising with immense pace worldwide. People living in developing countries are speculated to suffer the consequences due to economic deprivation and high cost of treatment. The prevalence of CKD is highly variable in different parts of the world, due to various environmental, ethnic, socioeconomical, and rural-urban differences. It has become very important for the developing countries to understand the true nature of the disease and its prevalence, rather than to hypothesize or make supposition on the bases of Western data. It is impera...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Imtiaz S, Salman B, Qureshi R, Drohlia MF, Ahmad A Tags: Saudi J Kidney Dis Transpl Source Type: research

The National Guard Health Affairs guidelines for the medical management of renal transplant patients.
Abstract PMID: 30588979 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Arabi Z, Theaby A, Farooqui M, Abdalla M, Hajeer A, Abdullah K Tags: Saudi J Kidney Dis Transpl Source Type: research

Safe correction of severe hyponatremia in patient with severe renal failure using continuous venovenous hemofiltration with modified sodium content in the replacement fluid.
We described a safe correction of severe hyponatremia in a 42-year-old male patient requiring dialysis, who was treated with continuous venovenous hemofiltration using hypotonic replacement fluid which was prepared and adjusted on a daily basis. PMID: 30588980 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Alqurashi BY, Gramish JA Tags: Saudi J Kidney Dis Transpl Source Type: research

Mammalian target of rapamycin inhibitors in a patient with polycystic kidney disease-1-tuberous sclerosis-2 contiguous gene syndrome.
We present a case report of a young girl who presented with skin lesions, central nervous system tubers, and cystic disease of the kidneys. She was treated with mammalian target of rapamycin inhibitors with a favorable outcome. PMID: 30588981 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Anandh U, Chandrasekar G, Agarwal V Tags: Saudi J Kidney Dis Transpl Source Type: research

Vitamin B1 for type B metabolic acidosis: An underrecognized approach.
We present a multifactorial case of lactic acidosis due to thiamine deficiency, liver disease, and lymphoma; all underrecognized causes of Type B lactic acidosis. PMID: 30588982 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Dejman A, Riveros J Tags: Saudi J Kidney Dis Transpl Source Type: research

Encapsulating peritoneal sclerosis associated with Burkholderia pseudomallei peritonitis.
We report a rare case of an end-stage renal disease patient on regular continuous ambulatory peritoneal dialysis (PD) who developed melioidosis PD peritonitis. Within a short period of time, she developed encapsulating peritoneal sclerosis evidenced by the intraoperative findings of intraabdominal cocooning. Choice and duration of antibiotic are important for proper eradication of the organism. Early diagnosis and treatment of both conditions also may improve the prognoses. PMID: 30588983 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Aulia Z, Wan Ali WASR, Shahar MA Tags: Saudi J Kidney Dis Transpl Source Type: research

Cerebral venous sinus thrombosis as a warning signal for double positive crescentic glomerulonephritis in a young male with complete renal recovery.
We present a young male who presented with CVT followed by rapidly progressive crescentic glomerulonephritis and with appropriate therapeutic modalities he had complete renal and partial neurological recovery. PMID: 30588984 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Jha VK, Padmaprakash KV, Pandey R, Sharda V, Sharma A Tags: Saudi J Kidney Dis Transpl Source Type: research

Relapsing Serratia peritonitis resulting in peritoneal catheter loss.
We present a case of a 40-year-old woman with end-stage renal disease secondary to chronic glomerulo-nephritis on continuous ambulatory peritoneal dialysis (PD). She presented with severe abdominal pain and a cloudy peritoneal fluid. The fluid was cultured according to our unit protocol. The organism isolated was identified as SM; this was after the patient was treated for SM peritonitis one week earlier. The response to treatment with ceftazidime was poor despite being sensitive in vitro. The peritoneal catheter was removed due to rapid clinical deterioration. Piperacillin-tazobactam (PIP/TAZ) monotherapy was successfully...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Kilic I, Gungor K, Kurultak I, Ustundag S Tags: Saudi J Kidney Dis Transpl Source Type: research

Bile cast nephropathy causing acute kidney injury in a patient with nonfulminant acute hepatitis A.
Abstract Hepatitis A is usually a benign self-limiting disease with few or no extrahepatic manifestations. Acute hepatitis A causing severe renal dysfunction is not very common, although described. Patients developing renal dysfunction post hepatitis A infection usually have prerenal acute kidney injury (AKI) or acute tubular necrosis due to vomiting, diarrhea, and poor fluid replacement. However, if renal dysfunction persists, other causes need to be evaluated. The term cholemic nephrosis or more specifically bile cast nephropathy has been described in the setting of cholestatic jaundice and decompensated liver f...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Ravi R, Suthar K, Murlidharan P, Lakshmi K, Balan S, Safeer M Tags: Saudi J Kidney Dis Transpl Source Type: research

Monoclonal B-cell lymphocytosis with renal involvement.
We report the case of a 70-year-old man with no relevant past medical history who presented with acute kidney injury. Kidney biopsy showed diffuse interstitial infiltration with typical chronic lymphocytic leukemia (CLL) phenotype B-cells. Subsequent studies revealed a normal lymphocyte count in the peripheral blood, and there was no evidence of lymphadenopathy or hepatosplenomegaly. Blood flow cytometry demonstrated a clonal B-cell population with a CLL phenotype. Without renal involvement, this case should be classified as monoclonal B-cell lymphocytosis. Renal function improved with steroid therapy. However, the patient...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Wen YK Tags: Saudi J Kidney Dis Transpl Source Type: research

Periarticular calcification mimicking inflammatory polyarthritis in chronic kidney disease.
Abstract Periarticular calcification is a frequent radiographic manifestation in chronic kidney disease (CKD). However, clinical presentation as inflammatory periarthritis, tenosynovitis, and bursitis is unusual. A 34-year-old man with CKD on dialysis for three years presented with painful swollen joints. His adherence to regular dialysis, phosphate binders, Vitamin D supplements, and antihypertension therapy was poor. He had swelling of the right thumb, index, and little fingers; periarticular swelling of the left middle finger and right little toe; and extensor tenosynovitis of the wrists and right olecranon bur...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Naidoo K, Ndlovu KCZ, Mody GM Tags: Saudi J Kidney Dis Transpl Source Type: research

Short-course metronidazole-induced reversible acute neurotoxicity in a renal transplant recipient.
We present a case of acute neurotoxicity due to short course of injectable metronidazole given in usual doses to a renal allograft recipient for persistent diarrhea. It responded to withdrawal of the offending drug. Tacrolimus trough concentration did not increase during neurotoxicity, thereby ruling out any metronidazole-tacrolimus interaction. Magnetic resonance imaging of the brain showed widespread osmotic demyelination and its recovery after drug withdrawal. This is the first reported case of a renal transplant recipient developing acute neurotoxicity due to short-term use of metronidazole, without any increase in tac...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Dogra PM, Bhatt AK, Agarwal SK, Bhowmik D Tags: Saudi J Kidney Dis Transpl Source Type: research

Ig M nephropathy - A clinicopathological study - Our experience.
Abstract PMID: 30588990 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Devi BV, Lakshmi BS, Padmavathi Devi SV, Ram R, Kumar VS Tags: Saudi J Kidney Dis Transpl Source Type: research

Magnitude of renal problem in fatal cases of Lassa fever: A summary on existed reports.
Abstract PMID: 30588991 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Yasri S, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Norovirus-associated hemolytic uremic syndrome in a renal transplant recipient.
Abstract PMID: 30588992 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Gaur L, Gupta A, Shingada A, Bhalla AK, Gupta A, Malik M, Bhargava V, Rana DS Tags: Saudi J Kidney Dis Transpl Source Type: research

Evaluation of glycemic status during the days of hemodialysis using dialysis solutions with and without glucose.
Abstract Hypoglycemia has been documented during regular hemodialysis (HD) in both diabetic and nondiabetic end-stage renal disease (ESRD) patients. The aim of this study was to evaluate the glycemic fluctuations in diabetic and nondiabetic ESRD patients during HD days using glucose-free and glucose-containing dialysate. We conducted a prospective interventional study in which 32 ESRD patients (16 diabetic and 16 nondiabetic) were included in the study. All the patients underwent two HD sessions with glucose-free bicarbonate solution (phase 1) and next two HD sessions done with 100 mg/dL glucose-containing dialysa...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Padmanabhan A, Velayudham B, Vijaykumar N, Allauddin S Tags: Saudi J Kidney Dis Transpl Source Type: research

Scores of awareness and altruism in organ transplantation among Saudi health colleges students-impact of gender, year of study, and field of specialization.
This study aimed to evaluate the awareness of organ transplantation and willingness to donate among Saudi Health Colleges students and the impact of gender, year of study, and field of specialization on this. This is a cross-sectional survey-based study. The survey was distributed to all the students attending the annual national conference of Saudi Health Colleges students held in 2018. The survey had two parts. The first part collected the information about gender, university, college of specialization, and year of study. The second part asked 10 questions, seven of which were about the types, causes, treatment of organ ...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: AlHejaili W, Almalik F, Albrahim L, Alkhaldi F, AlHejaili A, Al Sayyari A Tags: Saudi J Kidney Dis Transpl Source Type: research

Serum ferritin < 70 μg/L predicts functional iron deficiency in patients with chronic kidney disease.
Serum ferritin 18 years with hemoglobin
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Garg N, Kotru M, Yadav A, Rusia U, Sikka M, Kalra OP Tags: Saudi J Kidney Dis Transpl Source Type: research

Interleukin-6 gene polymorphisms and serum erythropoietin and hemoglobin in hemodialysis Iraqi patients.
This study aimed to evaluate the frequencies of 174G/C IL-6 gene promoter polymorphism in Iraqi hemodialysis (HD) patient and to examine the association between the allelic variations and serum erythropoietin (EPO) and hemoglobin (Hb) levels. The frequencies of IL-6 gene polymorphism were studied in 70 chronic renal failure patients on maintenance HD (patients group) and in 20 healthy participants (control group). Genotyping of IL-6 gene was performed by conventional polymerase chain reaction-restriction fragment length polymorphism. The distribution of IL-6 genotypes between groups was similar, and GG genotype is the most...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Al-Radeef MY, Allawi AAD, Fawzi HA Tags: Saudi J Kidney Dis Transpl Source Type: research

Study of therapeutic efficacy of febuxostat in chronic kidney disease stage IIIA to stage VD.
Abstract Hyperuricemia [serum uric acid (SUA)>7.0 mg/dL] which is common in chronic renal diseases is associated with augmented vascular events. In addition to nonpharmacological therapy, hypouricosuric drugs reduce UA levels. The current study was a prospective observational study of six months duration November 2016 to April 2017 done to determine the efficacy of febuxostat in patients with hyperuricemia in chronic kidney disease (CKD) stage G3a to G5 and to correlate any association with reduction of hypertension, improvement in glomerular filtration rate (GFR), and reduction in comorbidities. The study was ...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Sarvepalli PS, Fatima M, Quadri AK, Taher AR, Habeeb A, Amreen F, Parveen BN, Rajaram KG Tags: Saudi J Kidney Dis Transpl Source Type: research

Plantago major protects against cisplatin-induced renal dysfunction and tissue damage in rats.
This study revealed that P. major extract in a dose-dependent manner provides protection against renal damage induced by cisplatin. PMID: 30381501 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Parhizgar S, Hosseinian S, Soukhtanloo M, Bideskan AE, Hadjzadeh MA, Shahraki S, Noshahr ZS, Heravi NE, Haghshenas M, Rad AK Tags: Saudi J Kidney Dis Transpl Source Type: research

Clinical and laboratory profile of renal amyloidosis: A single-center experience.
Abstract The kidney is the most common organ involved in systemic amyloidosis. We aimed to study etiology and clinicopathological profile of renal amyloidosis. This was a retrospective study of 40 consecutive adult patients with biopsy-proven renal amyloidosis evaluated over a period of two years. Emphasis was given to describing the clinical presentation, renal function, proteinuria, type of amyloidosis, and its etiology. Mean age of the study cohort was 44 ± 15 years (with a male-to-female ratio of 3:1). Amyloid A (AA) amyloidosis was the most common type of amyloidosis observed in 72.5% of cases. Amyloid...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Engineer DP, Kute VB, Patel HV, Shah PR Tags: Saudi J Kidney Dis Transpl Source Type: research

Elimination of BK viremia in renal transplant recipients by optimization of immunosuppressive medications without precipitating acute rejection.
Abstract BK Polyomavirus-associated nephropathy (BKVAN) has been recognized as an increasing threat in renal transplant patients (RTP) for more than a decade. Reduction in immunosuppression is the mainstay of treatment through various options of treatment has been suggested. Published reports on these protocols have shown mixed results, and no randomized controlled trials have compared one strategy with another. In this context, we hypothesize that the appearance of BKV in the blood compels one to optimize the immunosuppression with possible long-term beneficial effects. We conducted a retrospective study among th...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Jha A, Ahmed W, Pakkyara A, Shaheen F, Al Salmi I Tags: Saudi J Kidney Dis Transpl Source Type: research

Red cell distribution width reflects the early stage residual renal function in peritoneal dialysis patients.
This study aimed to investigate the association of RDW with the residual renal function in peritoneal dialysis (PD) patients. The patients were categorized into three groups according to the quartiles of their baseline RDWs. The correlations between RDW and clinical parameters, dialysis adequacy, and residual renal function were analyzed. The clinical data, PD prescription and dialysis adequacy of 54 uremic patients on continuous ambulatory PD were collected. All the statistical analyses were performed using the Statistical Package for the Social Sciences program version 17.0. The baseline RDW of the patients was 13.56% &p...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Zhang Q, Cao X, Zhou J, Ding R, Huang J, Cai G, Chen X Tags: Saudi J Kidney Dis Transpl Source Type: research

The long-term impact of hepatitis C infection in kidney transplantation in the pre-direct acting antiviral era.
This study can serve as a benchmark for future studies to compare the long-term effect of Direct Acting Antiviral drugs. PMID: 30381505 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Radhakrishnan RC, Gopal B, Zachariah UG, Abraham P, Mohapatra A, Valson AT, Alexander S, Jacob S, Tulsidas KS, David VG, Varughese S Tags: Saudi J Kidney Dis Transpl Source Type: research

Assessment of hypertension and its associated risk factors among medical students in Qassim University.
The objective of the study is to assess the prevalence of hypertension and its associated risk factors in medical students attending the College of Medicine in Qassim University, Qassim, Saudi Arabia. It is a cross-sectional study that was conducted during the year 2017 on medical students attending the College of Medicine at Qassim University. A total of 130 students were selected using multistage stratified random sampling. We collected data on sociodemographic information and risk factors using a self-administered questionnaire derived from the WHO STEPS instrument, and we measured the blood pressure and body mass index...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: AlWabel AH, Almufadhi MA, Alayed FM, Aloraini AY, Alobaysi HM, Alalwi RM Tags: Saudi J Kidney Dis Transpl Source Type: research

Acute kidney injury in intensive care unit, hospital Universiti Sains Malaysia: A descriptive study.
In conclusion, AKI developed more in male patients, Malay ethnicity, presented with comorbid, caused by sepsis, admitted to ICU, required mechanical ventilation, and need for renal replacement therapy. PMID: 30381507 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Hamid SA, Adnan WW, Naing NN, Adnan AS Tags: Saudi J Kidney Dis Transpl Source Type: research

Saudi medical students knowledge, attitudes, and beliefs with regard to organ donation and transplantation.
This study examined whether knowledge of organ donation and transplantation (ODT) correlates with attitudes and beliefs relevant to ODT among medical students in Saudi Arabia. Two hundred and thirty-three students completed a self-administered questionnaire. A knowledge score was calculated for each student and correlated with answers on attitudes and beliefs with regard to ODT. This study revealed a complex interaction between knowledge, attitudes, and beliefs to ODT. The majority of students support ODT in general, but a significant proportion have negative beliefs when asked about specific details of the process and con...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: AlShareef SM, Smith RM Tags: Saudi J Kidney Dis Transpl Source Type: research

Acute kidney injury in hospitalized patients during muslim pilgrimage (Hajj: 1432).
Abstract Acute kidney injury (AKI) increases mortality and morbidity of hospitalized patients. We aimed to evaluate the prevalence of AKI, etiology, and associated risk factors among hospitalized patients during the Hajj time. Also to do comparative analysis for the use of slow continuous therapy versus conventional hemodialysis (HD) therapy on the patient outcome. The study was conducted between September 29 and November 25, 2011, inclusive (Islamic lunar dates Dhu'l-Qa'dah 1 to Dhul-Hijjah 29, 1432) at King Abdul-Aziz Hospital, a 250-bed hospital, in Makkah, Saudi Arabia. From 851 patients of 47 different countr...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Elrewihby WH, Hasan NF, Fikry W, Wafa E Tags: Saudi J Kidney Dis Transpl Source Type: research

Depression and impaired work productivity among hemodialysis patients in south region of Saudi Arabia.
Abstract Various studies have been published in different regions and countries about the prevalence of depression and its relationship with sociodemographic factors in patients on hemodialysis (HD). However, a gap in knowledge about the prevalence, correlates, detection, and treatment of depression and symptoms among dialysis patients in the Kingdom of Saudi Arabia. This is cross-sectional study to assess the prevalence of depression in HD patients and work productivity in Aseer region using Beck's questionnaire to screen depression and work productivity and activity impairment questionnaire to assess the work pr...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: AlShahrani MA, Alayed ASM, AlShehri AH, Solaiman O, Awadalla NJ, Alhomrany M Tags: Saudi J Kidney Dis Transpl Source Type: research

A clinical and electrophysiological study of peripheral neuropathies in peritoneal dialysis patients: Our experience from rural South India.
The objective was to study the prevalence, clinical features, electrophysiological features, and severity of peripheral neuropathy in chronic kidney disease (CKD) patients on peritoneal dialysis (PD) and effect of the presence of diabetes mellitus (DM). Between May 2015 and December 2016, 100 CKD patients on PD were assessed. The prevalence of peripheral neuropathy was 65% based on clinical symptoms and 92% based on electrophysiological parameters. The mean age was 55.7 ± 10.9 years. About 64% were male. Twelve patients (12%) had motor weakness, 64 patients (64%) had positive symptoms and 60 patients (60%) had negat...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Mallipeddi S, Jasti DB, Apparao A, Vengamma B, Sivakumar V, Kolli S Tags: Saudi J Kidney Dis Transpl Source Type: research

Risk factors of hospitalization among chronic kidney disease patients in tertiary care hospitals - A single-center experience.
Abstract Chronic kidney disease (CKD) affects health and life of patients. They confront anemia, hypertension, infections and cardiovascular disease. Due to these health issues, they are at risk of repeated hospitalizations. The risk factors which propel them to hospitalize are important to know, and by controlling these factors, we can impede preventable hospitalization. This case-control study included 1050 adult CKD patients, conducted in two tertiary care hospitals of Karachi. Variables included were age, gender, ethnicity, area of residence, marital status, education smoking status, comorbids, blood pressure,...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Salman B, Hussain M, Shafique K, Imtiaz S, Dhrolia MF Tags: Saudi J Kidney Dis Transpl Source Type: research

Histomorphological pattern of renal biopsy in Dhaka: A single center study.
We present the histomorphological characteristics of renal biopsy specimen received at histopathology department, Armed Forces Institute of Pathology, Dhaka received during July 2015 to December 2015 for six months period was included in the study. PMID: 30381513 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Islam SMJ, Haque WS, Akhter S, Mahbubul Alam SM Tags: Saudi J Kidney Dis Transpl Source Type: research

Prevalence of depression and its associated factors among patients of chronic kidney disease in a public tertiary care hospital in India: A cross-sectional study.
Abstract Chronic kidney disease (CKD) patients are at high risk of depressive disorders because of considerable psychological stress due to physical and social changes brought on by disease. The aim of this study is to assess the prevalence of depression in patients with CKD and the factors affecting it at a public tertiary care hospital. This cross-sectional study was carried out at the renal clinic of a tertiary care hospital. Data on 612 patients diagnosed with CKD from September 2014 to April 2016 was obtained. Nine-item Patient Health Questionnaire from PRIME-MD was used to assess the depression. Of all the p...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Ahlawat R, Tiwari P, D'Cruz S Tags: Saudi J Kidney Dis Transpl Source Type: research

Analysis of native kidney biopsy: Data from a single center from Bihar, India.
Abstract This is a retrospective study of all native kidney biopsies performed at our center between October 1, 2012 and March 31, 2015. Relevant clinical and laboratory variables were recorded. Biopsy samples were processed for light microscopy and immunofluorescence in all cases. Histological classification was adapted from the World Health Organization recommendations. The indications for kidney biopsy were nephrotic syndrome in adults in 190 cases, rapidly progressive renal failure in 43, unexplained renal failure in 25, and steroid-resistant nephrotic syndrome in children in 12. The mean age of the patients w...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Krishna A, Vardhan H, Singh PP, Kumar O Tags: Saudi J Kidney Dis Transpl Source Type: research

Expanding renal transplantation organ donor pool in Nigeria.
Abstract Kidney transplantation is the gold standard for end-stage renal disease. All over the world there are several challenges preventing sufficient organ donation to meet the growing needs of patients on the waiting list. One major challenge which is common to most countries is the shortage of organs from willing living donors. Many countries, especially, the developed countries, have devised several models of expanding their donor pools to meet the growing needs of patients on the waiting list. Nigeria, a developing country has very low kidney transplantation rate even though some progress have been made in m...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Popoola AA, Olanrewaju TO, Bolaji BO, Ajiboye TO Tags: Saudi J Kidney Dis Transpl Source Type: research

Chronic kidney disease in Sub-Saharan Africa.
Abstract Chronic kidney disease has been observed to be a major threat to the world's health, and in some African countries, it is a death sentence. It affects economically productive young adults between the ages of 20-50 in Sub-Saharan Africa as against the middle age and elderly in the developed world. Challenges of renal care in Africa are numerous among which are equity, accessibility, financial constraint, and lack of workforce to mention a few. Therefore, Africa countries must prioritize renal care and include it in the health agenda to cater for the present and future health need of the people. PMID: ...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Ogundele SB Tags: Saudi J Kidney Dis Transpl Source Type: research

Pattern of glomerulonephritis in the Kashmir valley.
This study may be useful to pathologists, nephrologists, and health care providers to formulate a basic platform for effective diagnostic, therapeutic, and research base for glomerular diseases so as to prevent its complications. PMID: 30381518 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Chowdry AM, Bhat MA, Najar MS, Sharma A, Azad H, Mir I Tags: Saudi J Kidney Dis Transpl Source Type: research

Acquired zinc deficiency in a renal transplant recipient with gastrointestinal tuberculosis responding promptly to oral correction.
Abstract Zinc deficiency is an uncommon condition, known to occur in two forms: inherited type, known as Acrodermatitis enteropathies and the acquired type. Cutaneous clinical manifestations observed include characteristic dermatitis on acral, periorificial, and anogenital areas through an unknown mechanism. The patient had a combination of causes which lead to a state of zinc deficiency. We are presenting it due to the rarity of acquired acrodermatitis in patients of gastrointestinal tuberculosis and renal transplant recipients. We emphasize the awareness about this condition, especially in resource-poor settings...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2018 Category: Urology & Nephrology Authors: Ghuge P, Karia R, Malkani RH Tags: Saudi J Kidney Dis Transpl Source Type: research