Comparison of intradialytic hemodynamic tolerance between on-line hemodiafiltration and acetate-free biofiltration with profiled potassium dialysate concentration.
Abstract Intradialytic hypotensive episodes are deleterious for hemodialysis (HD) patients. Acetate-free biofiltration with profiled potassium (AFBK) dialysate concentration may improve their cardiovascular stability. The aim of the present crossover study was to compare intradialytic hemodynamic tolerance and biological parameters between online hemodiafiltration (olHDF) and AFBK. Ten frail HD patients (8 males) with a mean age of 66.71- ± 12.31 years were studied for three months on olHDF and AFBK. There was a significant reduction of the hypotensive episodes during the AFBK period compared to the olHDF p...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Kosmadakis G, Correia EDC, Somda F, Aguilera D Tags: Saudi J Kidney Dis Transpl Source Type: research

A randomized controlled trial of the effects of hydrochlorothiazide on overactive bladder and idiopathic hypercalciuria.
Abstract Overactive bladder is a stressful condition which affects around 15%-20% of 5- year-old and up to 2% of young adults. One of the most common causes of overactive bladder is hypercalciuria. Our study investigated the effect of hydrochlorothiazide (HCTZ) on overactive bladder and hypercalciuria. This randomized controlled trial was conducted on 88 patients with overactive bladder and idiopathic hypercalciuria. They were randomly divided into the intervention group receiving 1 mg/kg/day of HCTZ for 3 months, and the control group receiving training without any intervention. Treatment compliance and response ...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Yousefichaijan P, Dorreh F, Rafiei M, Naziri M, Azimnejad A Tags: Saudi J Kidney Dis Transpl Source Type: research

Pattern of acute glomerulonephritis in adult population in Dubai: A single-center experience.
Abstract Epidemiological data of renal diseases have great geographic variability throughout the world. Due to the lack of a national renal data registry system, there is no information on the prevalence rate, clinical and pathological features of various glomerulonephritis (GN) in the United Arab Emirates (UAE). In a retrospective cross-sectional study, we analyzed 158 renal biopsies done in Dubai Hospital, UAE, between the years of 2005 and September 2014, with an aim to determine the prevalence rate and frequency of different pathological patterns of GN in adult patients who presented with proteinuria ± ...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Alhadari AK, Alalawi FJ, Seddik AA, Zahra K, Kumar D, Yousif H, Alnour H, Jansen M, Railey MJ Tags: Saudi J Kidney Dis Transpl Source Type: research

Postrenal transplant malignancy: Incidence, risk factors, and prognosis.
This study is designed to evaluate the incidence, risk factors, and types of malignancies occurring after renal transplantation and their impact on patient and graft survival. A total of 2288 patients underwent living donor renal allotransplantation in the Urology and Nephrology Center, Mansoura University, during the period between 1975 and 2011. Among these patients, 100 patients developed posttransplantation malignancy. Patients were categorized into five major groups according to their type of malignancy; Kaposi's sarcoma (KS), non-Kaposi's skin tumors (non-KS), posttransplant lymphoproliferative disorders (PTLD), soli...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Elserwy NA, Lotfy EE, Fouda MA, Mahmoud MI, Donia AF, Mashaly ME, Abbas MH, Abuelmagd MM, Abouelenein RK, Ismail MI, Bakr MA Tags: Saudi J Kidney Dis Transpl Source Type: research

Pediatric nephrology practice in Jordan.
Abstract The practice of pediatric nephrology in a developing country such as Jordan is governed by social, cultural, and economic issues. The prevalence of consanguinity contributes to the emergence of rare heredofamilial disorders and congenital anomalies of the kidneys and urinary tract. Epigenetic factors modify underlying genetic defect predisposing to symptomatic crystalluria. Future research should be directed at prevention. PMID: 28540897 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Akl K, Hazza I Tags: Saudi J Kidney Dis Transpl Source Type: research

Assessment of quality of life in children with nephrotic syndrome at a teaching hospital in South India.
This study was conducted to assess the quality of life (QOL) in children between 2 and 18 years of age with primary idiopathic nephrotic syndrome (NS) using Pediatric Quality of Life Inventory (PedsQL 4.0 Generic Core Scales). This cross-sectional comparative study was conducted at a tertiary care hospital in South India between December 2014 and February 2015. In this questionnaire-based study, 50 children with primary idiopathic NS and an equal number of age-matched controls with other chronic ailments were recruited. Their clinical and demographic details were recorded, and QOL was assessed using PedsQL 4.0 Generic Core...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Agrawal S, Krishnamurthy S, Naik BN Tags: Saudi J Kidney Dis Transpl Source Type: research

Gender differences in perceptions and attitudes of general population towards organ donation: An Indian perspective.
Abstract Globally, shortage of organs available for organ transplantation is a major problem. Studies assessing awareness and attitudes towards organ donation are limited from India. The aim of this study is to assess gender differences in the perceptions and attitude of general population toward organ donation. A cross-sectional descriptive study was carried out among randomly selected patient relatives (n = 193) at the outpatient department of a tertiary care center. Data were collected through face-to-face interview using a structured questionnaire. Our findings revealed that majority of men than women were awa...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Poreddi V, Sunitha TS, Thimmaiah R, Math SB Tags: Saudi J Kidney Dis Transpl Source Type: research

Quality of life of hemodialysis patients in Togo: A single-center study on 64 hemodialysis patients at the Sylvanus Olympio University Hospital in Lom é, Togo.
This study aims at assessing patients' quality of life during hemodialysis (HD) and determining influencing factors. This prospective study was conducted over a three-month period (December 1, 2012-February 28, 2013) at the Sylvanus Olympio University Hospital (CHU-SO) HD unit, the only center to provide such services in Togo. Respondents used the standard Medical Outcome Survey-Short Form 36 questionnaire. This study was conducted on 64 patients (44 males and 20 females = M/F ratio 2.2). Mean patient age was 45.51 ± 14.00 years old with the vast majority in the 16-44-year-old group (90.82%), and mean dialysis vinta...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Sabi KA, Noto-Kadou-Kaza B, Amekoudi EY, Vigan J, Ayamekpe K, Amedegnato D Tags: Saudi J Kidney Dis Transpl Source Type: research

Postinfectious glomerulonephritis with a broken heart: A case report study.
PMID: 28540901 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Omer H, Ali A, Aljizeeri A, Uthman E Tags: Saudi J Kidney Dis Transpl Source Type: research

Primary focal segmental glomerulosclerosis recurring rapidly as collapsing glomerulopathy in a renal allograft recipient.
We report a patient who received a live- related renal transplant for end-stage renal disease due to a primary FSGS (not otherwise specified) in the native kidney and presented with graft dysfunction in the immediate posttransplant period. The first and the second biopsy showed no evidence of rejection or glomerular lesion. A repeat biopsy done on the 30th day revealed recurrent FSGS morphologically presenting as collapsing variant. The patient was found to have massive proteinuria. Electron microscopy done retrospectively showed glomerular foot process effacement even in the first biopsy. This case highlights the presence...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Agrawal V, Prasad N, Singh P Tags: Saudi J Kidney Dis Transpl Source Type: research

Recurrent syndrome of inappropriate antidiuretic hormone secretion due to tolterodine in an elderly male patient.
Abstract Hyponatremia is defined as serum sodium of
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Alhwiesh AK, Alsharani H, Ibrahim EF, Alanazi Z, AlGhamdi BA, Alaudah N, Alzahrani F, Alsarawi A, Almohaws A, Abdurrahman IS Tags: Saudi J Kidney Dis Transpl Source Type: research

Utilization of plasmapheresis in the management of bismuth intoxication with acute renal failure.
kel Y Abstract A 34-year-old female patient who ingested 2400 mg bismuth subcitrate in a suicide attempt was brought to the emergency department. She had mild encephalopathy and acute renal failure on admission. One session of plasmapheresis was performed to remove bismuth, and needed three sessions of hemodialysis and was discharged on the 24th day of hospitalization with the recovery of the renal function. PMID: 28540904 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Disel NR, Açikalin A, Sebe A, Gokel Y Tags: Saudi J Kidney Dis Transpl Source Type: research

Tuberous sclerosis complex (Bourneville-Pringle disease) in a 25-year- old female with bilateral renal angiomyolipoma and secondary hypertension.
We report such a rare case of tuberous sclerosis in a 25-year-old female who presented with abdominal pain and hypertension. Physical examination showed dermatological signs that included hypopigmented maculae, shagreen plaque, angiofibromas on the centrofacial areas, periungual fibromas on toes, and molluscum pendulum around the neck. Abdominal ultrasonography revealed bilateral renal angiomyolipoma. Brain magnetic resonance imaging showed subependymal nodules and cortical tubers. She also presented retinal and oral lesions. Our patient has a definitive diagnosis of TSC. Hypertension was related to the renal involvement o...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: El Aoud S, Frikha F, Snoussi M, Salah RB, Bahloul Z Tags: Saudi J Kidney Dis Transpl Source Type: research

An overlap of granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis.
We report a 45-year-old female who presented with rapidly progressive renal failure associated with fever, polyarthralgia, and respiratory symptoms with cytoplasmic antineutrophilic cytoplasmic antibody (ANCA) and proteinase (PR-3) antigen positivity. Computerized tomography scan of the chest showed diffuse alveolar hemorrhage with renal biopsy revealing pauci-immune necrotizing crescentic glomerulonephritis with intense eosinophilic infiltration suggestive of eosinophilic GPA (EGPA). Our patient had ANCA-associated vasculitis (AAV) with features suggestive of both GPA and EGPA. She was treated with methylprednisolone and ...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Surendran S, Gundappa C, Gandhi A, Kurien AA, Fernando E Tags: Saudi J Kidney Dis Transpl Source Type: research

Oliguric acute kidney injury as initial presentation of renal non-Hodgkin's lymphoma infiltration.
We report a case of a 20-year-old man presented to the emergency department with oliguria and renal failure requiring urgent dialysis. An ultrasound revealed enlarged kidneys, and a renal biopsy showed non-Hodgkin's lymphoma, subtype diffuse large B-cell. PMID: 28540907 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Leite TT, Libório AB, Silva Junior GB, Daher EF Tags: Saudi J Kidney Dis Transpl Source Type: research

Two unusual cases of microvascular thrombosis in the immediate posttransplant period.
We present two unusual cases of microvascular thrombosis in the immediate posttransplant period resulting in graft loss. The first was a 20-year-old female with a cadaveric renal transplant with immediate graft dysfunction due to microthrombi of probable donor origin, with nonrecovery of renal function nine months' posttransplant. The second was a 23-year-old male with unrelated live kidney transplant with hyperacute rejection due to anti-endothelial antibodies. PMID: 28540908 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Gowrishankar S, Krishnan S, Ravishankar MS, Nuguri S Tags: Saudi J Kidney Dis Transpl Source Type: research

Unusual presentation of systemic lupus erythematosus.
Abstract Bullous systemic lupus erythematosus is a rare distinctive subepidermal blistering disorder that can occur in patients with systemic lupus erythematosus (SLE). It is histologically characterized by a neutrophil-predominant infiltrate in the subepidermal region with deposition of immunoglobulins (IgG, IgA, IgM), C3, and auto-antibodies against collagen VII. Herein, we report a case of a 13-year-old girl who presented with bullous SLE and Class III lupus nephritis, which is extremely rare at this age. PMID: 28540909 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Mahesh E, Madhyastha PR, Varma V, Gurudev KC, Gireesh MS, Bande SR Tags: Saudi J Kidney Dis Transpl Source Type: research

Rituximab-induced urticarial dermatitis during the treatment of membranous nephropathy.
Abstract Rituximab is a monoclonal antibody directed against B cells and is being increasingly used for various renal indications. Acute dermatologic manifestations such as urticaria are well known to occur during rituximab infusion. Here, we report the case of a 53- year-old female who was treated with rituximab for membranous nephropathy and developed an exanthematous rash, which progressed with a further dose of rituximab and was diagnosed as urticarial dermatitis. A review of literature showed that urticarial dermatitis following rituximab therapy has been seldom reported and identification of this complicatio...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Radhakrishnan RC, Basu G, George RE, Parmar H, Tamilarasi V Tags: Saudi J Kidney Dis Transpl Source Type: research

Hand-assisted laparoscopic donor nephrectomy: A single-center study.
PMID: 28540911 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Shohab D, Jamil I, Khan IA, Khawaja MA, Khan MA, Akhter S Tags: Saudi J Kidney Dis Transpl Source Type: research

The role of hypercalciuria in pathogenesis of recurrent abdominal pain.
PMID: 28540912 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Malaki M Tags: Saudi J Kidney Dis Transpl Source Type: research

New-onset diabetes after kidney transplantation and the role of cytomegalovirus.
PMID: 28540913 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Lotfiazar A, Einollahi B, Zijoud SMH, Shahyad S Tags: Saudi J Kidney Dis Transpl Source Type: research

Dengue and acute kidney injury: A need for aggressive maneuvers.
PMID: 28540914 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Mallhi TH, Khan AH, Khan YH, Adnan AS, Sarriff A Tags: Saudi J Kidney Dis Transpl Source Type: research

Author's reply.
PMID: 28540915 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Peritonitis associated with infective endocarditis and vertebral osteomyelitis in a peritoneal dialysis patient.
PMID: 28540916 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Wen YK Tags: Saudi J Kidney Dis Transpl Source Type: research

Factors affecting on hepatitis B seroprotection in hemodialysis patients.
PMID: 28540917 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Malaki M Tags: Saudi J Kidney Dis Transpl Source Type: research

Asymptomatic bilateral giant angiomyolipoma.
PMID: 28540918 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2017 Category: Urology & Nephrology Authors: Kaur G, Thajudeen B Tags: Saudi J Kidney Dis Transpl Source Type: research

Obesity and kidney disease: Hidden consequences of the epidemic.
Abstract Obesity has become a worldwide epidemic, and its prevalence has been projected to grow by 40% in the next decade. This increasing prevalence has implications for the risk of diabetes, cardiovascular disease and also for chronic kidney disease (CKD). A high body mass index is one of the strongest risk factors for new-onset CKD. In individuals affected by obesity, a compensatory hyperfiltration occurs to meet the heightened metabolic demands of the increased body weight. The increase in intraglomerular pressure can damage the kidneys and raise the risk of developing CKD in the long-term. The incidence of ob...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Kovesdy CP, Furth S, Zoccali C, World Kidney Day Steering Committee Tags: Saudi J Kidney Dis Transpl Source Type: research

Update on pathogenesis, management, and treatment of hypertension in autosomal dominant polycystic kidney disease.
Abstract Hypertension is a common early finding in autosomal dominant polycystic kidney disease (ADPKD). Improvements in screening and diagnosis of ADPKD have allowed earlier diagnosis, later onset of end-stage renal disease, and better survival. However, the main and most effective therapy remains control of hypertension. Hypertension is the most important modifiable risk factor in ADPKD. Therefore, early management of hypertension reduces the incidence of cardiovascular events in ADPKD patients. Stimulation of the renin-angiotensin-aldosterone system (RAAS) plays a central role in the pathogenesis of hypertensio...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Helal I, Al-Rowaie F, Abderrahim E, Kheder A Tags: Saudi J Kidney Dis Transpl Source Type: research

Associations between clinical characteristics and angiotensin-converting enzyme gene insertion/deletion polymorphism in Moroccan population with Type-2 diabetic nephropathy.
Abstract Diabetic nephropathy (DN) is one of the severe complications of Type-2 diabetes mellitus (T2DM) and a major cause of end-stage renal disease in these patients. Results from published studies on the relationship between angiotensin-converting enzyme (ACE) insertion/ deletion (I/D) gene polymorphism and patients with DN are still conflicting. We compared the clinical characteristics and the genotype frequencies of ACE polymorphism in 130 T2DM Moroccan patients with DN and 85 T2DM Moroccan patients without DN (controls) using specific primers in a polymerase chain reaction. The degenerative complications of ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Mansouri M, Zniber A, Boualla L, El Badaoui G, Benkacem M, Rifai K, Chraibi A, Benamar L, Sefiani A, Bayahia R Tags: Saudi J Kidney Dis Transpl Source Type: research

Assay of urinary protein carbonyl content can predict the steroid dependence and resistance in children with idiopathic nephrotic syndrome.
In this study, 70 cases of INS were enrolled, and urinary protein carbonyl content (UPCC) was estimated by Levine's method before starting the steroid therapy. All the cases were followed up and, based on the response to steroid therapy, were grouped as Group A (n = 47). Steroid sensitive and Group B (n = 23), SD + SR cases. UPCC was significantly higher in Group B compared to Group A. Receiver-operating curve showed at a cutoff limit of 5.10 nmoles/mg of protein, UPCC can predict SD or SR cases with 83.3% sensitivity and 85.2% specificity and area under the curve of 0.833, P
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Gopal N, Koner BC, Bhattacharjee A, Bhat V, Murugaiyan SB, Muddegowda PH Tags: Saudi J Kidney Dis Transpl Source Type: research

Dynamic renal scintigraphic estimation of deceased donor kidneys in a rat model.
ı TA Abstract At present a large number of the renal transplantations are being performed from the deceased donors. The success of these transplantations depends on the viability of the deceased donor kidneys. The aim of this study was to investigate the reliability of scintigraphic estimation of function of deceased donor kidneys by comparing the histopathologic and scintigraphic findings. Ten rats were included in the study (2-3 months old, 250-300 g, all male). Control scintigraphy was performed to all the rats by injection of 37 MBq Tc-99m DTPA from the tail vein in a dynamic manner. Brain death of the rats w...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Mitil HA, Koç ZP, Guzel Y, Kom M, Ozer AB, Ozercan IH, Balcı TA Tags: Saudi J Kidney Dis Transpl Source Type: research

Spectrum of renal injury in pregnancy-induced hypertension: Experience from a single center in India.
In this study, we found a low rate of preeclampsia in a low-to-moderate risk cohort, with an incidence of AKI and maternal mortality consistent with reported literature. PMID: 28352008 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Eswarappa M, Rakesh M, Sonika P, Snigdha K, Midhun M, Kaushik K, Chennabasappa GK, Sujeeth B Tags: Saudi J Kidney Dis Transpl Source Type: research

Validation of bioelectrical impedance analysis for assessing dry weight of dialysis patients in Pakistan.
Abstract Accurate dry weight estimation (DW) to achieve euvolemia is one of the key objectives of hemodialysis (HD). While conventionally DW is estimated by clinical examination, bioelectrical impedance analysis (BIA) has been proposed as an objective method to determine DW and has been tested extensively in the Western population. We aim to validate BIA for determining DW in a Pakistani population against the conventional clinician's method. This is a single-center validation study conducted at two outpatient HD units of Aga Khan Hospital, Karachi. One hundred and forty-eight DW readings of patients who were on m...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Asmat H, Iqbal R, Sharif F, Mahmood A, Abbas A, Kashif W Tags: Saudi J Kidney Dis Transpl Source Type: research

Anatomical study of renal and accessory renal arteries.
Abstract In recent years, more conservative methods of surgery of the renal artery are coming up. Hence, a precise knowledge of renal vasculature has become a necessity. Knowledge of the existence of accessory renal arteries is important; otherwise, they may get inadvertently damaged during renal surgery. Furthermore, their presence must be considered while evaluating a donor's kidney for possible renal transplantation. The study may also be useful to clinicians performing invasive techniques, vascular surgeries, other uro-radiological procedures, and in cases of trauma. Keeping this in mind, this study was conduc...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Jamkar AA, Khan B, Joshi DS Tags: Saudi J Kidney Dis Transpl Source Type: research

Biopsy of small kidneys: A safe and a useful guide to potentially treatable kidney disease.
Abstract Over the past four years, all patients with unexplained rapid progression of their renal disease were subjected to kidney biopsy, despite their small size (
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: El-Reshaid K, El-Reshaid W, Al-Bader D, Varro J, Madda J, Sallam HT Tags: Saudi J Kidney Dis Transpl Source Type: research

Clinical variables differentiating diabetic from nondiabetic kidney disease in patients with diabetes: A single-center study.
Abstract Patients with diabetes may have kidney diseases other than the diabetic kidney disease. Kidney biopsy is the investigation of choice when this is suspected. This retrospective analysis included all patients known to have diabetes mellitus (DM) and who had a kidney biopsy at our center between 1998 and 2014. The aim of this study was to assess if an association exists between the clinical factors on the presence or absence of diabetic nephropathy (DNP). A total number of 206 patients were included in our study. The association between the diabetic retinopathy (DRP) and DNP was high (P = 0.001). We found th...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Imtiaz S, Salman B, Nasir K, Drohlia MF, Ahmad A Tags: Saudi J Kidney Dis Transpl Source Type: research

Factors influencing patency of Brescia-Cimino arteriovenous fistulas in hemodialysis patients.
In this study, a total of 134 patients and 138 fistulas were evaluated from April 2015 to March 2016. Demographic factors and clinical factors were taken into consideration. Our study showed that age, sex, diabetes, and type of construction (end-to-side vs. side-to-side) had no influence over fistula patency rates. Intradialytic hypotension was one of the risk factors for loss of fistula patency. Smoking and history of hypertension were associated with reduced patency rates (P
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Manne V, Vaddi SP, Reddy VB, Dayapule S Tags: Saudi J Kidney Dis Transpl Source Type: research

Risk factors for contrast-induced nephropathy after coronary angiography.
Abstract Contrast-induced nephropathy (CIN) is of concern after the use of radiocontrast media for coronary angiography (CAG) and percutaneous coronary intervention (PCI). We studied the incidence of CIN and its risk factors in patients undergoing CAG. In this prospective study, we included all patients with normal renal parameters undergoing CAG with nonionic radiocontrast media. We excluded patients with known chronic kidney disease, baseline creatinine more than 1.5 mg/dL, significant hypotension, anemia, and patients with acute myocardial infarction undergoing emergency PCI. Serum creatinine was done at baseli...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Kumar S, Nair RK, Aggarwal N, Abbot AK, Muthukrishnan J, Kumar KV Tags: Saudi J Kidney Dis Transpl Source Type: research

Association between angiotensin-converting enzyme insertion/deletion gene polymorphism and end-stage renal disease in lebanese patients with diabetic nephropathy.
Abstract Diabetic nephropathy (DN) is one of the leading causes of end-stage renal disease (ESRD). The development and progression of nephropathy is strongly determined by genetic factors, and few genes have been shown to contribute to DN. An insertion/deletion (I/D) polymorphism of the gene encoding angiotensin-converting enzyme (ACE) was reported as a candidate gene predisposing to DN and ESRD. Accordingly, we investigated the frequency of ACE I/D polymorphism in 50 patients with DN, of whom 33 had ESRD and compared them with 64 patients with type 2 diabetes mellitus (T2DM) but with normal renal function. Polyme...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Fawwaz S, Balbaa M, Fakhoury H, Borjac J, Fakhoury R Tags: Saudi J Kidney Dis Transpl Source Type: research

Associated anomalies and clinical outcome in children with ectopic kidney.
Abstract Urological anomalies can be seen in children with renal ectopia (RE) and can result in renal impairment. Therefore, we evaluated associated anomalies and renal outcome in our patients with RE. Sixty-eight children who were diagnosed with RE between January 2009-May 2014 were retrospectively studied. A total of 68 patients, 36 (52.9%) boys, with a median age of 67 months (4-201) and a median follow-up period of 14 months (3-113) were included in the study. Simple RE (S-RE) was found in 51 (75%) patients, of which 46 were unilateral and five were bilateral (discoid kidney). Crossed RE (C-RE) was detected in...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Dogan CS, Dorterler ME, Aybar MD, Ciftci H, Gulum M, Akin Y, Yeni E Tags: Saudi J Kidney Dis Transpl Source Type: research

Basilic vein transposition: A viable alternative for multiple failed arteriovenous fistulas - A single center experience.
Abstract Primary use of the autogenous arteriovenous access is recommended by the National Kidney Foundation-Dialysis Outcomes Quality Initiative guidelines. In spite of troublesome comorbidities associated with basilic vein transposition (BVT), it is still the most preferred technique when autologous veins are not suitable to construct radio-cephalic fistula (RCF) and brachiocephalic fistula (BCF), arteriovenous fistula (AVF). The present study highlights our experience with BVT, with small incision technique, over a period of two years with excellent outcome. This retrospective study included all the patients wh...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Chipde SS, Agrawal S, Kalathia J, Mishra U, Agrawal R Tags: Saudi J Kidney Dis Transpl Source Type: research

Depression and anxiety disorders in chronic hemodialysis patients and their quality of life: A cross-sectional study about 106 cases in the northeast of morocco.
Abstract Hemodialysis (HD) has a severe impact on the life of HD patients. The aim of this work was to assess the prevalence of depression and anxiety disorders, suicidal ideation, and the quality of life among HD patients. Associated factors were also studied. A cross-sectional study was carried out among 103 HD patients treated at the HD Center of Al Farabi Hospital of Oujda during a period of six months in 2015. The Mini-International Neuropsychiatric Interview and European Quality of Life-5 Dimensions (EQ-5D) were used for the assessment. Major depressive episode (MDE) was found in 34% of our patients, whereas...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: El Filali A, Bentata Y, Ada N, Oneib B Tags: Saudi J Kidney Dis Transpl Source Type: research

Analysis of patients with end-stage renal disease on dialysis in Tabuk City, Saudi Arabia: A single-center, three-year retrospective study.
This study was performed to analyze various demographic data such as age, gender, nationality, status of the patients, and the causes of end-stage renal disease (ESRD) of 349 patients who were undergoing hemodialysis (HD) during the period from January 2013 to December 2015 at the Dialysis Center of King Khalid Hospital in Tabuk City. One hundred and fifty-two patients (43.6%) were on HD in 2015. Age of the patients ranged from 9 to 93 years and the mean age was 51.3 ± 17.6 years. Majority of the patients, i.e., 140 (40.1%) were in the age group of 40-59 years, followed by the age group of 60-79 years by 27.8% (97 p...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Almutairi FM, Al-Duais MA, Shalaby KA, Sakran MI Tags: Saudi J Kidney Dis Transpl Source Type: research

Profile of glomerular diseases associated with hepatitis B and C: A single-center experience from India.
Abstract Hepatitis B and C are known to affect kidneys in a number of ways. Glomerular diseases associated with hepatitis B and C include membranous nephropathy (MN), membranoproliferative glomerulonephritis (MPGN), focal segmental glomerulosclerosis, immunoglobulin A nephropathy, rarely amyloidosis, and fibrillary and immunotactoid glomerulopathy. In a retrospective analysis of kidney biopsy of 534 patients, we found 16 (2.9%) patients of hepatitis B and 11 (2.05%) patients of hepatitis C with glomerular disease. The most common form of glomerulonephritis in hepatitis B patient was MN and in hepatitis C patient w...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Raveendran N, Beniwal P, D'Souza AV, Tanwar RS, Kimmatkar P, Agarwal D, Malhotra V Tags: Saudi J Kidney Dis Transpl Source Type: research

Prevalence of the metabolic syndrome in kidney transplant recipients: A single-center study.
Abstract Metabolic syndrome (MS) is characterized by a combination of cardiovascular (CV) risk factors (hypertension, dyslipidemia, obesity, and alterations in glucose homeostasis). Insulin resistance is suggested to be the common pathogenic background. This syndrome is also a risk factor for diabetes and chronic kidney disease. In renal transplant recipients, MS has been shown to be an independent risk factor for chronic allograft dysfunction, graft failure, new-onset diabetes, and CV disease. We performed a cross-sectional study on 106 stable renal transplant recipients to detect MS between January 2013 and Augu...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Hami M, Sabbagh MG, Sefidgaran A, Mojahedi MJ Tags: Saudi J Kidney Dis Transpl Source Type: research

Analysis of renal diseases detected in renal biopsies of adult patients: A single-center experience.
This study shows that focal segmental glomerulosclerosis is the most common lesion in renal biopsy in the young age group followed by membranous nephropathy. Diabetic nephropathy and chronic interstitial nephritis were dominant secondary pathological lesions in older age group, whereas lupus nephritis was the most common secondary disease in young age females. PMID: 28352022 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Imtiaz S, Drohlia MF, Nasir K, Salman B, Ahmad A Tags: Saudi J Kidney Dis Transpl Source Type: research

Anti-glomerular basement membrane: A rare cause of renal failure in children.
We report a case of 11-year-old child with acute renal failure secondary to anti-GBM disease and associated with antineutrophil cytoplasmic antibody-positive vasculitis. He was treated with plasmapheresis, steroids, and cyclophosphamide with recovery of his kidney functions. PMID: 28352023 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Agarwal I, Al-Ghitany A Tags: Saudi J Kidney Dis Transpl Source Type: research

Anesthetic management of two cases of Bardet-Biedl syndrome for renal transplantation.
We report two cases of typical BBS in a 17-year-old female and 29-year-old male patient, who presented for live-related renal transplant. We discuss the relevant points of the syndrome regarding anesthetic management. PMID: 28352024 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Vora KS, Modi MP, Butala BP, Shah VR Tags: Saudi J Kidney Dis Transpl Source Type: research

Eculizumab experience in an adult patient with atypical hemolytic uremic syndrome.
In this study, we present a case of a patient with atypical hemolytic-uremic syndrome treated successfully with eculizumab. A 20-year-old female was admitted with clinical signs of atypical hemolytic syndrome. The laboratory findings were as follows: hemoglobin 9.2 g/dL, platelet count 18 × 103/μL, creatinine 4.69 mg/dL, schistocytes were in peripheral blood smear, lactate dehydrogenase 2080 U/L, and emergency plasmapheresis procedure with fresh frozen plasma were initiated. The patient was anuric within 12 h of her admittance. ADAMTS13 activity was normal. Her mother's cousin developed acute rejection immediately...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Sari F, Inci A, Karakus V, Yilmaz B, Sarikaya M, Olmaz R, Kurtoglu E Tags: Saudi J Kidney Dis Transpl Source Type: research

Hyponatremia secondary to acute urinary retention.
Abstract Acute urinary retention is a rare cause of hyponatremia. Symptomatic acute hyponatremia is of grave medical concern and needs to be managed aggressively. In our two cases with acute urinary retention, a simple bladder catheterization and drainage of urine followed by conservative management resulted in complete resolution of symptoms and normalization of sodium levels. Association of bladder distension and hyponatremia is considered to be due to release of vasopressin triggered by bladder distension itself or by pain due to bladder distension. These cases are presented to bring to light an unusual and eas...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2017 Category: Urology & Nephrology Authors: Parikh J, Dhareshwar S, Nayak-Rao S, Ramaiah I Tags: Saudi J Kidney Dis Transpl Source Type: research