Long-term health consequences of living kidney donation: From the perspective of donors.
PMID: 31464263 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2019 Category: Urology & Nephrology Authors: Khan MT, Hamid R, Ali AS Tags: Saudi J Kidney Dis Transpl Source Type: research

Immune checkpoint inhibitors for progressive multifocal leukoencephalopathy.
PMID: 31464264 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2019 Category: Urology & Nephrology Authors: Venniyoor A Tags: Saudi J Kidney Dis Transpl Source Type: research

Probability of Ganciclovir Resistance in Cytomegalovirus-Infected Pediatric Kidney Transplant Recipients after Cessation of Standard Antiviral Prophylaxis: Estimated Risk on Thai cases.
PMID: 31464265 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2019 Category: Urology & Nephrology Authors: Yasri S, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Rabies, rabies vaccine, and renal failure: Clinical issues.
Abstract Rabies is an important neurological infection that is prevalent in tropical countries. The rabid animals can bring rabies to humans by biting. The disease can result in serious neurological problem and death is the end result. The best way is prevention of disease by postexposure prophylaxis against rabies. The effect of rabies on the renal system is little mentioned in the literature. In the previous literature, acute kidney injury was observable in half of the rabies patients. Rabies is also transmittable by organ transplantation. Although it is rare and
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Sriwijitalai W, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Perinephric transplant fluid collection approach and management.
This article reviews the differential diagnoses of perirenal fluid collections in postrenal transplant period and focuses on the clinical assessment of urinoma and management options according to the latest evidence-based medicine. PMID: 31249219 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Alshamsi I, Alshamsi H, Al Falahi S, Sharma A, Halawa A Tags: Saudi J Kidney Dis Transpl Source Type: research

Vascular calcification in patients with chronic kidney disease on dialysis in the Kingdom of Saudi Arabia: A cross-sectional study.
Abstract The study aimed to provide a unique nationwide data and a valuable update on the current situation of vascular calcification (VC) among chronic kidney disease (CKD) patients in the Kingdom of Saudi Arabia. The study included all patients diagnosed with CKD over a period of one year and six months from September 2015 to February 2017 and underwent dialysis. All analyses were done using IBM-SPSS. Of the 842 enrolled patients, 836 (99.3%) constituted the descriptive population. The mean age of patients was 51.8 ± 15.4 years. A total of 759 (90.8%) patients had cardiovascular risk factors. The prevalen...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: AlGhonaim MA, Fathalla AA Tags: Saudi J Kidney Dis Transpl Source Type: research

Using single-item survey to study the prevalence of burnout among medical residents-influence of gender and seniority.
In conclusion, 50% of the residents had burnout which was significantly more prevalent in females. The rate of burnout is the highest in the last year of training and the lowest in the 1st year. PMID: 31249221 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: AlSayari RA Tags: Saudi J Kidney Dis Transpl Source Type: research

Estimating glomerular filtration rate in adult kidney transplant recipients in the Asian population.
Abstract Estimation of glomerular filtration rate (GFR) in renal transplant patients is often assessed by application of creatinine-based equations. The aim was to correlate the estimated GFR (eGFR) using creatinine-based equations [Cockroft-Gault, Modification of Diet in Renal Disease (MDRD), Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), Nankivell] with gold standard 51Cr-EDTA in kidney transplant patients in the Asian population. This is a single-center, cross-sectional study involving adult renal transplant patients. Background demographic data, medications, office blood pressure, and baseline in...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Kamaruzaman L, Mohd R, Zaki FM, Hod R, Aziz AA Tags: Saudi J Kidney Dis Transpl Source Type: research

Incidence and risk factors of common viral infections among renal transplant recipients during the first year post-transplant in North-eastern Iran.
Abstract Despite major therapeutic advances, management of viral infections in renal transplant recipients is still a major challenge. Hence, it is urgently needed to establish protocols for appropriate control and the prevention of viral infection. We evaluated demographic/clinical characteristics, frequency, and risk factors of symptomatic viral infections in renal transplant recipients during the 1st year posttransplant, in northeastern Iran. We retrospectively reviewed medical files of 247 patients including 146 males and 101 females who had undergone renal transplantation at Montaserie organ transplantation h...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Eidgahi ES, Lotfi Z, Tayefi M, Bahrami A, Shams SF, Shakeri S, Sheikhi M Tags: Saudi J Kidney Dis Transpl Source Type: research

The use of sirolimus in patients with recurrent cytomegalovirus infection after kidney transplantation: A retrospective case series analysis.
Abstract Cytomegalovirus (CMV) is one of opportunistic infections post solid organ transplant and remains a cause of morbidity and mortality. Mammalian target of rapamycin inhibitors has a theoretical antiviral advantage compared to conventional immunosuppression. The primary outcome was to assess the viremic response and kidney function in a cohort of kidney transplant recipients (KTRs) with difficult to manage CMV infection when converted to sirolimus. We retrospectively analyzed the outcome of substituting sirolimus for mycophenolate mofetil (MMF) or tacrolimus in 18 KTR with difficult to manage, resistant/recu...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Shendi AM, Hung RKY, Caplin B, Griffiths P, Harber M Tags: Saudi J Kidney Dis Transpl Source Type: research

Evaluation of dialysis practice patterns in children having end-stage renal disease on maintenance hemodialysis at a pediatric nephrology unit.
Abstract Hemodialysis (HD) involves purifying the blood of waste products through diffusion through a semipermeable membrane. We aimed to evaluate dialysis practice patterns among children with end-stage renal disease (ESRD) on maintenance HD (MHD). This cross-sectional study was conducted on 30 children with ESRD on MHD at the pediatric nephrology unit of Menoufia University and 18 age- and sex-matched children who served as the control group. Consent was obtained from children more than seven years old and their parents and from parents of younger children. They were all subjected to full history, complete physi...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: El-Mashad GM, Omar ZA, Seif ES Tags: Saudi J Kidney Dis Transpl Source Type: research

Pattern of renal diseases and the need for establishment of renal biopsy registry in Saudi Arabia.
Abstract Renal disease is a common medical problem in Saudi Arabia. Varieties of renal lesions if not treated properly or not discovered early will lead to a chronic kidney disease. Identifying the types of renal lesions can help in identifying the high-risk patients and appropriate treatment can be provided. Glomerulonephritis (GN) is considered one of the leading causes of end-stage renal disease in Saudi Arabia. The prevalence of different renal lesions were identified by different reports; however, these reports showed inconsistency. One important reason for such differences is related to the lack of unified m...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Al-Homrany M, Alghamdi S, Al-Hwiesh A, Mousa D, Alwakeel J, Mitwalli A, Alsaad K, Alharbi A, Kari J Tags: Saudi J Kidney Dis Transpl Source Type: research

Effect of high-dose Omega 3 on lipid profile and inflammatory markers in chronic hemodialysis children.
This study aimed to evaluate the effect of high-dose Omega 3 on lipid profile and inflammatory markers in ESRD children on chronic HD. This clinical trial was conducted on 49 ESRD children on chronic HD selected from pediatric HD unit of Menoufia University Hospital. The study was conducted for a period of three months. The selected children were supplemented with 2000-mg Omega 3 tablets daily; lipid profile and inflammatory markers were assessed at the beginning and at the end of the study. Supplementation with high-dose Omega 3 resulted in a highly statistically significant decrease in total cholesterol, triglyceride, lo...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Omar ZA, Montser BA, Farahat MAR Tags: Saudi J Kidney Dis Transpl Source Type: research

A study of the main determinants of kidney allograft long-term survival in the era of new immunosuppressive drugs.
Abstract The outcome of long-term kidney allograft is extremely important. The present study aimed to discern the factors affecting long-term kidney allograft survival, including the type of donation and the use of extended criteria donors. Seven hundred and thirty-seven kidney transplant alone patients entered this retrospective cross-sectional study. The impact of different factors on death-censored long-term kidney allograft survival was evaluated. The Cox proportional survival model was employed to identify these factors. A value of P
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Hekmat R, Sturdevant M Tags: Saudi J Kidney Dis Transpl Source Type: research

Creatinine and cystatin C-based evaluation of renal function among obese subjects in Benin City, Nigeria.
Abstract Obesity is a recognized worldwide epidemic with increasing prevalence in developing nations. Studies have shown that obesity is an independent risk factor for the development of chronic kidney disease (CKD) besides its link with diabetes mellitus and hypertension. We evaluated the renal status of obese patients using both the established [creatinine (Cr)] and new (cystatin C) markers of renal function. This was a cross-sectional study. Fifty-nine consenting adults attending the clinic for routine medical checks were recruited for this study. They were divided into obese and non-obese based on their body m...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Alaje AK, Adedeji TA, Adedoyin AR, Idogun SE Tags: Saudi J Kidney Dis Transpl Source Type: research

ABO incompatible kidney transplantation: the Saudi experience.
In this study, we aimed to determine the graft and patient survival in ABOi kidney transplant recipients in the Saudi population. We included all adult patients who underwent ABOi transplantation between 2007 and 2016. All patients received rituximab, therapeutic plasma exchange, thymoglobulin, intravenous antibiotics, and intravenous immunoglobulin. The maintenance immunosuppression was prednisone, mycophenolate mofetil, and tacrolimus. The data were collected from a prospectively maintained database. A total of 77 patients were included in the study. The most common blood group mismatch was A to O (44.2%), followed by B ...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Ali T, Broering D, Aleid H, Brockmann J, Alhumaidan H, Hammad E, Shah Y, Elgamal H, Alahmadi I, Hussein M, Raza S, Alabassi A, Ibrahim I, Shoukri M, Almeshari K Tags: Saudi J Kidney Dis Transpl Source Type: research

Cryoglobulinemia in a moroccan nephrology department.
Abstract Cryoglobulinemia is a rare cause of kidney disease that occurs in patients with various diseases. Renal involvement often occurs after appearance of various clinical manifestations dominated by purpura and neuropathy. The aim of this study is to describe clinical, biological, and pathological characteristics of cryoglobulinemic glomerulonephritis (GN), as well as treatment and outcome. This is a retrospective study including all patients with positive cryoglobulin test and biopsy-proven GN secondary to cryoglobulinemia. Fourteen patients with cryoglobulinemic GN were collected. Their mean age was 46.92 &p...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Azizi M, Rafik H, Zajjari Y, Montasser DI, El Kabbaj D Tags: Saudi J Kidney Dis Transpl Source Type: research

Management of phosphate abnormalities in hemodialysis patients: Findings from Malaysia.
In this study, we attempted to determine treatment characteristics for patients with end-stage renal disease (ESRD) on maintenance hemodialysis (MHD) having hyperphosphatemia or hypophosphatemia in comparison with those with normal phosphate level. This was a cross-sectional survey conducted at HD units of Central Pahang Cluster Hospitals, Malaysia, in April 2017 involving 110 ESRD patients on MHD. About 40% of the study patients had normo-or hyperphosphatemia. As many as 84.5% (n = 93) of our patients were prescribed calcium carbonate (CC); the phosphate level was not affected by phosphate binder (PB) adherence. None of o...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Mohamed Koya SNM Tags: Saudi J Kidney Dis Transpl Source Type: research

Epidemiology, diagnosis, and etiology of acute kidney injury in the elderly: A retrospective analysis.
Abstract The increased incidence of the acute kidney injury (AKI) in the elderly is becoming a disturbing reality in our days, mainly with the aging of the general population, and the predisposition of old persons to chronic diseases, drug toxicity, and infections. The aim of this study was to investigate the epidemiological, clinical, and biological features and to assess variant etiologies and outcomes of AKI in the elderly. Data were collected from the medical records of patients older than 65 years age having AKI admitted in the Internal Medicine Department of the Military Hospital of Tunis from January 2006 t...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Selmi Y, Ariba YB, Labidi J Tags: Saudi J Kidney Dis Transpl Source Type: research

A study of prevalence and correlates of nonadherence to immunosuppressive medications in renal transplant recipients of South Indian population and their impact on long-term graft function.
In this study, we sought to assess the prevalence and correlates of nonadherence to immunosuppressants and its impact on graft function. A singlecenter, retrospective cum cross-sectional study of renal transplant recipients of age>18 years and who had completed at least six months after transplantation was performed. Nonadherence was assessed based on the Immunosuppressant Therapy Adherence Scale questionnaire. Factors attributed to nonadherence were assessed based on the Immunosuppressant Therapy Barriers Scale (ITBS) questionnaire. Social, economic, demographic data, and all transplant related information were recorde...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Saravanakumar K, Prakash A, Thopalan B, Dhanapriya J, Thanigachalam D, Ramanathan S, Gopalakrishnan N Tags: Saudi J Kidney Dis Transpl Source Type: research

Asymptomatic proteinuria in Indonesian adolescent students.
This study aimed to find out the prevalence of asymptomatic persistent proteinuria in adolescent students. This was a multi-assessment study. Screening for proteinuria was conducted on five junior high schools across Jakarta, Indonesia, in April-June 2015. Healthy students aged 12-14 years whose parents provided informed consent were selected randomly. Urine collections were performed thrice. We used dipstick tests and protein-to-creatinine ratio to measure protein in the urine. From 536 students, 485 were eligible and recruited for this study. They were more female and well-nourished students. Hypertension constituted 12....
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Trihono PP, Wulandari N, Supriyatno B Tags: Saudi J Kidney Dis Transpl Source Type: research

Does severe ADAMTS13 deficiency in thrombotic microangiopathy rule out complement-mediated atypical hemolytic uremic syndrome.
Abstract In evaluating a patient with thrombotic microangiopathy (TMA), it is necessary to rule out thrombotic thrombocytopenic purpura before a diagnosis of atypical hemolytic uremic syndrome (aHUS) is made. There have been reports that mutations of complement factors can coexist with partial A Disintegrin and Metalloproteinase with a ThromboSpondin type 1 motif, member 13 deficiency. Here, we report the case of a 6-year-old girl who was initially diagnosed as nephrotic syndrome and developed TMA after five years of onset of illness. She had poor response to treatment and had multiple relapses due to associated c...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Arumugam V, Bhowmick R, Agarwal I, Arumadi M Tags: Saudi J Kidney Dis Transpl Source Type: research

Gas in the kidney in asymptomatic Escherichia coli urinary tract infections in a patient with severe vesicoureteral reflex.
Abstract Diabetes mellitus (DM) is a common disease in Oman as in rest of Gulf Cooperation Council where metabolic syndrome is of high prevalence. DM is a foremost risk factor for urinary tract infections (UTIs). It is also linked to more complicated infections such as emphysematous pyelonephritis (EPN), emphysematous pyelitis (EP), renal/perirenal abscess, emphysematous cystitis, xanthogranulomatous pyelonephritis, and renal papillary necrosis. The diagnosis of these cases is frequently delayed because the clinical manifestations are generic and not different from the typical triad of upper UTI, which include fev...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Pakkyara A, Jha A, Al Salmi I, Mohammed E, Jothi V, Al Lawati S, Al Maamari S, Faisal FAM Tags: Saudi J Kidney Dis Transpl Source Type: research

Stroke and renal artery stenosis from Takayasu's arteritis diagnosed in a 57-year-old male patient.
We report a case of a 57-year-old male patient with late diagnosis of TA and various related complications including stroke in the left middle cerebral artery territory, predominant left renal artery stenosis, and hypertension with discrepancy of blood pressure between two arms due to predominant left subclavian artery stenosis. Thus, physicians should keep in their mind this late presentation after the age of 40 years. The aim is to increase the awareness of this condition because of early diagnosis and the timely introduction of treatment can lead to improved outcomes in this poorly understood clinical enigma. PMID:...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Ur Rahman SS, Al Shehri A, Al Ghamdi M, Al Shareef M Tags: Saudi J Kidney Dis Transpl Source Type: research

Bilateral endophthalmitis and symmetrical peripheral gangrene in a patient with chronic kidney disease on maintenance hemodialysis.
Abstract Dialysis patients have greater number of complications due to multiple comor-bidity and access-related infections as well as nosocomial infections due to reduced immunity and more frequent hospitalizations. Endogenous endophthalmitis is a potentially blinding ocular infection occurring in chronically debilitated patients and the use of invasive procedures. Symmetric peripheral gangrene (SPG) is defined as symmetrical distal ischemic damage in two or more sites in the absence of a major vascular occlusive disease. It carries a high mortality rate with a very high frequency of multiple limb amputations in t...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Nath JD, Kashem A, Osman AM, Das T Tags: Saudi J Kidney Dis Transpl Source Type: research

Recurrence of membranoproliferative glomerulonephritis post transplant - Is this mere recurrence of pattern or recurrence of disease?
Abstract Recurrence of membranoproliferative glomerulonephritis (MPGN) is seen in 1965% cases of postrenal transplant resulting in graft loss in up to 35-50% of cases. A 31-year-old female, after 1% years on maintenance hemodialysis, underwent ABO compatible deceased donor kidney transplantation with basiliximab induction. During the immediate posttransplant period, the patient had delayed graft function, but achieved nadir creatinine of 0.9 mg/dL by 10 days. Nine months posttransplant, the patient developed fever, anasarca, and decrease in urine output with albuminuria 3+, active sediments in urine, serum creatin...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Lingaraj U, Patil SR, Aralapuram K, Mallappa SS, Gurusiddaiah SC, Vankalakunti M Tags: Saudi J Kidney Dis Transpl Source Type: research

Adenine phosphoribosyltransferase deficiency and 2, 8-dihydroxyadenine renal stones: A preventable cause of pediatric renal stones and kidney disease.
Abstract Adenine phosphoribosyltransferase deficiency is an inherited condition presenting from infancy to late adulthood. The common features are recurrent kidney and urinary tract stones and obstructive symptoms. The stones are characteristically radiolucent. 2, 8-Dihydroxyadenine (2, 8-DHA) formation is blocked by xanthine oxidase blocker allopurinol. Here, we report the case of an eight-month-old baby girl who presented with obstructive acute kidney injury secondary to calculi which was treated with surgical removal of stone. The analysis of the calculi revealed 2, 8-DHA crystals. PMID: 31249241 [PubMed -...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Parikh MD, Konnur A, Gang S Tags: Saudi J Kidney Dis Transpl Source Type: research

Manifest interstitial and vascular pathology in anti-neutrophil cytoplasmic antibody-associated renal disease.
Abstract Rapidly progressive renal failure in anti-neutrophil cytoplasmic antibody (ANCA)- associated renal disease customarily implies crescentic glomerulonephritis with approximately 50% of the glomeruli will have crescents. The tubulointerstitial inflammation is often proportionate to the glomerular inflammation and may have granulomatous pattern adjacent to the glomeruli or an inflamed vessel. A 77-year-old male with rapidly progressive renal failure was myeloperoxidase-ANCA positive, and renal histopathology revealed thrombotic microangio-pathy, significant interstitial inflammation, interstitial granulomas, ...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Haridasan S, Ganesh RN, Parameswaran S, Priyamvada PS Tags: Saudi J Kidney Dis Transpl Source Type: research

Acute kidney injury due to sucrose-containing intravenous immunoglobulins.
We report the case of a renal transplant patient who developed AKI due to sucrose nephropathy following the administration of sucrose-containing IVIG. PMID: 31249243 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Siddiqui W, Al Lawati S, Shaheen Faissal AM, Hannawi S, Al Riyami M, Al Salmi I Tags: Saudi J Kidney Dis Transpl Source Type: research

A very rare pathogen in peritoneal dialysis peritonitis: Serratia liquefaciens.
We report a case of Serratia liquefaciens peritonitis due to defiance of hygienic practices which presented with severe abdominal pain and fever and led to loss of PD access. PMID: 31249244 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Helvaci O, Hızel K, Guz G, Arinsoy T, Derici U Tags: Saudi J Kidney Dis Transpl Source Type: research

Biochemical profile of mineral and bone disorder in prevalent hemodialysis patients.
PMID: 31249245 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Alquraini FR, Alnazer RH, Albahrani OA, Alkhars R, Almueilo SH Tags: Saudi J Kidney Dis Transpl Source Type: research

Experience of systemic lupus erythematosus in South-Western Bangladesh.
PMID: 31249246 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Ul Azim MA, Salam A, Abdullah SN Tags: Saudi J Kidney Dis Transpl Source Type: research

Inferior vena cava compression and acute kidney injury.
PMID: 31249247 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Nakano H, Imai N, Shibagaki Y Tags: Saudi J Kidney Dis Transpl Source Type: research

Ralstonia infection among hemodialysis patients: A summary.
PMID: 31249248 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Sriwijitalai W, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Estimated prevalence of BK virus infection from screening among kidney transplant recipients: A summary from an Indochina country.
PMID: 31249249 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Sookaromdee P, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Prognostication of acute kidney allograft rejection through urinary molecular signatures: A noninvasive approach to ameliorate kidney rejection dynamics.
PMID: 31249250 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Hamid RB, Khan MT, Ali AS Tags: Saudi J Kidney Dis Transpl Source Type: research

Sulfamethoxazole crystal-induced acute kidney injury.
PMID: 31249251 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2019 Category: Urology & Nephrology Authors: Han W, Imai N, Kohatsu K, Suzuki T Tags: Saudi J Kidney Dis Transpl Source Type: research

Burden, access, and disparities in kidney disease.
Abstract Kidney disease is a global public health problem, affecting over 750 million persons worldwide. The burden of kidney disease varies substantially across the world, as does its detection and treatment. In many settings, rates of kidney disease and the provision of its care are defined by socio-economic, cultural, and political factors leading to significant disparities. World Kidney Day 2019 offers an opportunity to raise awareness of kidney disease and highlight disparities in its burden and current state of global capacity for prevention and management. Here, we highlight that many countries still lack a...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2019 Category: Urology & Nephrology Authors: Crews DC, Bello AK, Saadi G, World Kidney Day Steering Committee Tags: Saudi J Kidney Dis Transpl Source Type: research

Therapeutic plasma exchange for children with kidney disorders: Definitions, prescription, indications, and complications.
Abstract Therapeutic plasma exchange (TPE) is a procedure that involves the removal of a large volume of plasma that is replaced with a replacement fluid, which is usually 5% albumin or fresh-frozen plasma. This therapeutic modality presents several technical challenges in children but has become increasingly used in pediatric nephrology. Owing to advances in technology, scientists have gained substantial knowledge of the molecular pathogenesis underlying many pediatric renal diseases, supporting the use of TPE in treating these disorders. This review presents a synopsis of the literature as it relates to the acce...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2019 Category: Urology & Nephrology Authors: Alhasan KA Tags: Saudi J Kidney Dis Transpl Source Type: research

Birth weight, gestational age, and blood pressure: Early life management strategy and population health perspective.
Abstract The incidence of hypertension (HTN) is rising worldwide with an estimated prevalence of 22%, 7.5 million deaths (12.8%). It is a major risk factor for coronary heart diseases and hemorrhagic strokes. In Oman, the crude prevalence of HTN was 33.1%, whereas the age-adjusted prevalence was 38.3%. Among Gulf Cooperation Countries, 47.2% of the individuals were hypertensive, and women were more likely to have HTN than men. Similarly, the prevalence of low-birth-weight (LBW) is also rising globally with the more prevalent incidence in developing countries reaching almost a rate just lower than 20.0/100 births. ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2019 Category: Urology & Nephrology Authors: Al Salmi I, M Shaheen FA, Hannawi S Tags: Saudi J Kidney Dis Transpl Source Type: research

Chyluria in pregnancy: Etiology, diagnosis, and management perspective.
Abstract Chyluria is clinically described as passage of milky urine. Chyle is absorbed by intestinal lacteals and is composed of emulsified fats, few proteins, and fibrin in varying proportions. Parasitic chyluria is caused mainly by Wuchereria bancrofti infection. The incidence of chyluria in pregnancy is not uncommon in endemic regions. The literature pertaining tomedical management of chyluria in pregnancy is scant. The antifilarial drugs have potential teratogenic risk and are not recommended in pregnant patients. Hence, there is a management dilemma for managing patients with chyluria during pregnancy. In thi...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2019 Category: Urology & Nephrology Authors: Purkait B, Garg G, Singh M, Sharma A, Pandey S, Sankhwar SN Tags: Saudi J Kidney Dis Transpl Source Type: research

Association of hepcidin and anemia in early chronic kidney disease.
Abstract Hepcidin is being extensively studied for anemia and inflammation in chronic kidney disease (CKD) patients. Hepcidin is thought to regulate iron metabolism by iron blockade through various mechanisms. Patients with CKD have early cardiac mortality due to anemia and subclinical inflammation; hence, we studied hepcidin as a biomarker in patients with early stage of CKD in relation to anemia and inflammation. In our cross-sectional study, a total of 80 patients were enrolled of whom, there were 25, 26, and 29 patients in CKD stages 1, 2, and 3, respectively. Patients were divided into normal iron level (39),...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2019 Category: Urology & Nephrology Authors: Sonkar SK, Singh NK, Sonkar GK, Pandey S, Bhosale V, Kumar A, Usman K Tags: Saudi J Kidney Dis Transpl Source Type: research

Acute cortical necrosis in pregnancy still an important cause for end-stage renal disease in developing countries.
In conclusion, strategies need to be implemented in reducing the preventable causes for RCN which is not only catastrophic in terms of renal outcomes but also for social and psychological perspectives as well. PMID: 31031368 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2019 Category: Urology & Nephrology Authors: Kaul A, Lal H, Mishra P, Jain M, Prasad N, Pradhan M, Patel MR, Gupta A, Sharma RK Tags: Saudi J Kidney Dis Transpl Source Type: research

Seroconversion following hepatitis B vaccination in children with chronic kidney disease.
This study aimed to assess the seroconversion and persistence of protective immunity following hepatitis B vaccination in children with CKD. This prospective observational study was conducted in a tertiary pediatric nephrology centre to assess the seroconversion and maintenance of antibody titers (>10 mIU/mL) at one year following hepatitis B vaccination (10 μg at 0, 1, and 2 months) in children with CKD Stages II to V. Those who did not seroconvert after the schedule were re-vaccinated, and antibody titers were checked. Categorical data were expressed as proportions and analyzed using the Chi-square test. Pearson's ...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2019 Category: Urology & Nephrology Authors: Kamath N, Vasudevan A, Iyengar A Tags: Saudi J Kidney Dis Transpl Source Type: research

Status of fasting in Ramadan of chronic hemodialysis patients all over Egypt: A multicenter observational study.
Abstract There is a paucity of data concerning safety of fasting in Ramadan in chronic kidney disease patients on hemodialysis (HD). The aim of the present study was to assess the frequency of fasting in Ramadan in HD patients in Egypt and the possible effect of fasting on clinical and biochemical variables. This observational multicentric study was carried out during 2016 when fasting duration was around 16 h. PMID: 31031370 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2019 Category: Urology & Nephrology Authors: Megahed AF, El-Kannishy G, Sayed-Ahmed N Tags: Saudi J Kidney Dis Transpl Source Type: research

A study of detection and comparison of immunofluorescence on formalin-fixed paraffin-embedded tissue with fresh frozen renal biopsy specimen.
Abstract Direct immunofluorescence on the fresh frozen tissue is established way of demonstrating of immunoglobulins and complement deposition in renal biopsies. IF studies can be done on paraffin-fixed tissue (IF-P) and give comparable results to those obtained on frozen tissue for most pathogenic immunoglobulins and immunoglobulin fragments; although, the detection of C3c may be more problematic. In our study, we used proteinase-K method for antigen retrieval. We aimed to detect immunoglobulins and complements in formalin-fixed paraffin-embedded (FFPE) tissue sections from renal biopsies and have comparison of I...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2019 Category: Urology & Nephrology Authors: Solanki R, Solanki MK, Hemrajani D, Saha J Tags: Saudi J Kidney Dis Transpl Source Type: research

Postoperative complications in living liver donors: A retrospective study, single-center experience in Saudi Arabia.
This study is designed to identify postoperative complications in LDLT in a tertiary care center King Abdulaziz Medical City (KAMC). This was a retrospective cohort study. All donors at KAMC between January 2003 and December 2015 were reviewed through a hospital database and patient charts to determine the postoperative complications based on the modified Clavien classification system. All donors were relatives of the recipients and assessed before the surgery. A total of 101 donors underwent LDLT: 75 were male and 26 were female, with a mean age of 27.7 ± 6.6. The breakdown of specific surgical procedures was as fo...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2019 Category: Urology & Nephrology Authors: Althonaian NA, Alsaiari AS, Almanea WA, Alsubaie NJ, Almuharimi AA, Althubaiti A, Altamimi AR, Abdullah KO, Ohali WA Tags: Saudi J Kidney Dis Transpl Source Type: research

Impact of age and gender matching on long-term graft function and actual graft survival in live-related renal transplantation: Retrospective study from Sindh Institute of Urology and transplantation, Pakistan.
Abstract In renal transplantation, donor and allograft age are known to have an important influence on the outcome of the graft, reflecting functional renal mass. We evaluated the impact of gender and age matching in living-donor renal transplantation on long-term graft survival and actual graft function over five years from the day of transplantation. We retrospectively analyzed 500 primary live-related donor renal transplants performed from August 2007 to December 2008 at Sindh Institute of Urology and Transplantation, Karachi, Pakistan. Donors and recipients were divided into two age groups [young (YD) and elde...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2019 Category: Urology & Nephrology Authors: Shahani MM, Iqbal T, Idrees MK Tags: Saudi J Kidney Dis Transpl Source Type: research

Acute-phase proteins as promoters of abdominal aortic calcification in chronic dialysis patients.
Abstract The aim of this study was to find a correlation between acute-phase proteins (APPs) and abdominal aortic calcification (AAC) as well as the impact APPs on AAC in chronic dialysis patients (CDPs). Native lateral lumbar radiography and biochemical analysis were performed in 112 CDPs (aged 60.0 ± 5.43 years) to estimate and score AAC and biochemical values of APPs. The mean AAC score was 8.39 ± 5.43. We detected 16 (14.28%) CDPs without AAC and 96 (85.71%) CDPs with AAC (10 ± 5.43). The number of CDPs with AAC ≤4 was 34 (30.36%) with mean AAC score of 1.85 ± 1.94. By multiple r...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2019 Category: Urology & Nephrology Authors: Avramovski P, Avramovska M, Sotiroski K, Sikole A Tags: Saudi J Kidney Dis Transpl Source Type: research

The role of matrix metalloproteinases 2 in atherosclerosis of patients with chronic kidney disease in type 2 diabetes.
Abstract Matrix metalloproteinase-2 (MMP2) has been implicated in chronic disease and cardiovascular disease. However, there is no knowledge about the correlations between serum levels of MMP-2, proteinuria and atherosclerosis in patients with diabetic nephropathy (DN). We investigated whether serum MMP-2 levels were associated with proteinuria, intima-media thickness (IMT) in DN patients. Diabetic patients not on hemodialysis (n = 50) were enrolled for the study. MMP-2 levels were measured using an ELISA system. IMT was evaluated by highresolution ultrasonography. Univariate analyses revealed that MMP-2 (P = 0.01...
Source: Saudi Journal of Kidney Diseases and Transplantation - March 1, 2019 Category: Urology & Nephrology Authors: Soliman AR, Sadek KM, Thabet KK, Ahmed DH, Mohamed OM Tags: Saudi J Kidney Dis Transpl Source Type: research