Comparison of serum creatinine, cystatin C, and neutrophil gelatinase-associated lipocalin for acute kidney injury occurrence according to risk, injury, failure, loss, and end-stage criteria classification system in early after living kidney donation.
Abstract To evaluate the kidney function after living kidney donation, we measured serum creatinine (SCr), cystatin C, and neutrophil gelatinase-associated lipocalin (NGAL) of 42 living donors before uninephrectomy and in three immediate days after it. We also evaluated the prevalence of the occurrence of the different stages of acute kidney injury (AKI) classified according to risk, injury, failure, loss, and end-stage (RIFLE) criteria, and accuracy of each of these three biomarkers for predicting them were evaluated. Significant serum NGAL (s-NGAL) changes were limited to the 1 st day after donation, whereas SCr...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Hekmat R, Mohebi M Tags: Saudi J Kidney Dis Transpl Source Type: research

Effects of induction therapy with alemtuzumab versus antithymocyte globulin among highly sensitized kidney transplant candidates.
Abstract We retrospectively compared induction therapy utilizing alemtuzumab and antithymoglobulin (ATG) in high-risk kidney transplant recipients in our center. Two hundred and fifty-one patients underwent kidney transplantation between 2009 and 2012. The high-risk patients were defined as those who had two or more times kidney transplantation and/or more than 30% panel reactive antibody. We studied 130 high-risk kidney transplant candidate; 58 (44.6%) patients received induction immunosuppressive therapy with alemtuzumab, and 72 (55.4%) with ATG. Delayed graft function developed in 11 patients receiving alemtuzu...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Shamsaeefar A, Roozbeh J, Khajerezae S, Nikeghbalian S, Kazemi K, Motazedian N, Geramizadeh B, Malekhosseini SA Tags: Saudi J Kidney Dis Transpl Source Type: research

Relationship between renal volume calculated by using multislice computed tomography and glomerular filtration rate calculated by using the Cockcroft-Gault and modification of diet in renal disease equations in living kidney donors.
This study was conducted to investigate the correlation between renal volume and the GFR values in potential living kidney donors referred to the multislice imaging center at Alzahra Hospital during 2014. The study comprised 66 subjects whose GFR was calculated using the two aforementioned formulas. Their kidney volumes were measured by using 64-slice CT angiography and the correlation between renal volume and GFR values were analyzed using the Statistical Package for the Social Science software. There was no correlation between the volume of the left and right kidneys and the MDRD-based estimates of GFR (P = 0.772, r = 0....
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Adibi A, Mortazavi M, Shayganfar A, Kamal S, Azad R, Aalinezhad M Tags: Saudi J Kidney Dis Transpl Source Type: research

Interaction between blood and dialysis membrane in hepatitis-C virus-infected patients: A comparative study.
This study aimed to answer the following question: In HD patients, does chronic HCV infection attenuate the acute inflammatory response that results from contact of patient's blood with the dialyzer membrane? We elected to investigate the contact response in the initial 15 min of a standardized single dialysis session in a before-after design. Thus, we compared magnitude of dialysis-induced changes in total leukocyte counts, platelet counts, and C3a levels in a cohort of HCV-infected and a cohort of non-infected dialysis patients (57 patients in each group). Distribution of gender, age groups, and hypertension was comparab...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Ahmed S, El-Sherif A Tags: Saudi J Kidney Dis Transpl Source Type: research

Prevalence and correlates of Willis-Ekbom's disease/restless legs syndrome in patients undergoing hemodialysis.
Abstract Willis-Ekbom's disease/restless legs syndrome (WED/RLS) has been described in subjects undergoing hemodialysis (HD). Different studies have reported varying prevalence rates and different factors associated with this condition; however, the results are inconsistent. Thus, this study was conducted to assess the prevalence of WED/RLS in patients undergoing HD. Another aim of the study was to identify if any comorbidities or biochemical factors were associated with this condition. A total of 194 adult patients undergoing maintenance HD were included in this study. They were screened for WED/RLS using Interna...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Bathla N, Ahmad S, Gupta R, Ahmad S Tags: Saudi J Kidney Dis Transpl Source Type: research

Cardiovascular disease risk profiles comparison among dialysis patients.
This study was performed to assess the cardiovascular disease (CVD) risk factors in the prevalent peritoneal dialysis (PD) and hemodialysis (HD) patients and their association with cardiovascular events (CVEs) in a Saudi end-stage renal disease cohort. This was a prospective, observational, single-center study. A total of 192 patients were screened of which 157 patients were eligible (HD = 121, PD = 36). All patients underwent assessment of cardiovascular risk factors at the time of enrollment including electrocardiogram and echocardiography, lipid profile, homocysteine, and insulin levels. Patients were followed for one y...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Sharabas I, Siddiqi N Tags: Saudi J Kidney Dis Transpl Source Type: research

Pentraxin-3 in hemodialysis patients: Relationship to comorbidities.
In conclusion, PTX-3 appears to be a clinically useful marker for the early identification of patients with renal failure on maintenance HD who are at substantially increased risk of morbidity. These patients may require care and aggressive follow-up in more specialized units and an early referral to a renal transplant center. PMID: 27424686 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: El Sebai AA, El Hadidi ES, Abdel Al H, El Sayed EY Tags: Saudi J Kidney Dis Transpl Source Type: research

Comparative evaluation of efficacy and safety profile of rhubarb and α-keto analogs of essential amino acids supplementation in patients with diabetic nephropathy.
Comparative evaluation of efficacy and safety profile of rhubarb and α-keto analogs of essential amino acids supplementation in patients with diabetic nephropathy. Saudi J Kidney Dis Transpl. 2016 Jul-Aug;27(4):710-6 Authors: Khan IA, Nasiruddin M, Haque SF, Khan RA Abstract To determine the efficacy and safety profile of rhubarb and α-keto analogs of essential amino acids supplementation in patients of diabetic nephropathy (DN), we studied 96 patients of DN attending a tertiary care center of the North India. The patients were randomly divided into three equal interventional groups. Group...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Khan IA, Nasiruddin M, Haque SF, Khan RA Tags: Saudi J Kidney Dis Transpl Source Type: research

Mycophenolate mofetil versus azathioprine for maintenance treatment of lupus nephritis.
Abstract To compare the efficacy of mycophenolate mofetil (MMF) with that of azathioprine (AZA) drugs in the maintenance therapy of lupus nephritis (LN) patients, we studied 81 Sudanese patients with LN (32 in Class III, 34 in Class IV, and 15 in combined Class V + IV of the ISN/RPS 2003 Classification). All patients received induction therapy consisting of monthly intravenous pulse doses of cyclophosphamide (CYC) (500 mg/m 2 of body-surface area) for six months, plus three consecutive pulses of intravenous methylprednisolone 15 mg/kg/day of body weight (maximum 500 mg). Subsequently, 41 (50.6%) patients were rand...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Kaballo BG, Ahmed AE, Nur MM, Khalid IO, Abu-Aisha H Tags: Saudi J Kidney Dis Transpl Source Type: research

Evaluation of aldosterone excretion in very low birth weight infants.
Abstract Data about aldosterone production and excretion in the neonatal period are still few and controversial. Our objectives are to assess urinary aldosterone excretion (UAE) in very low birth weight (VLBW) infants and to identify clinical and biochemical variables that may influence this excretion. Thirty VLBW infants (14 males and 16 females), their gestational age
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Abdel Mohsen AH, Taha G, Kamel BA, Maksood MA Tags: Saudi J Kidney Dis Transpl Source Type: research

Nutritional assessment in children with chronic kidney disease.
This study was aimed to assess nutritional intake and anthropometry of children presenting with CKD in a developing country. In this cross-sectional observational study, children (1-18 years) with CKD visiting the outpatient services were enrolled. The age of onset, cause of CKD, and anthropometry were recorded. Dietary intakes from three 24 h dietary recall (2 mid-week and 1 weekend day) were recorded. A blood sample was taken from all subjects for biochemical parameters. A total of 45 children (forty males and five females) with CKD underwent nutritional assessment. The median age at assessment was 108 months (13-167). T...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Gupta A, Mantan M, Sethi M Tags: Saudi J Kidney Dis Transpl Source Type: research

Acute kidney injury in critically ill child.
Abstract Acute kidney injury (AKI) is a common and serious complication in patients in the Pediatric Intensive Care Unit (PICU). We conducted this study to estimate the incidence and the mortality rate of AKI in critically ill children as well as to describe some other related factors. A retrospective study was conducted at PICU of Queen Rania Abdulla Children Hospital, Amman, Jordan for the period extending from May 2011 to June 2013. The medical records of all patients admitted during this period, and their demographic data were reviewed. Patients with AKI were identified, and management and outcomes were review...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Al-Jboor W, Almardini R, Al Bderat J, Frehat M, Al Masri H, Alajloni MS Tags: Saudi J Kidney Dis Transpl Source Type: research

Gastrointestinal bleeding due to angiodysplasia in patients on hemodialysis: A single-center study.
Abstract Gastrointestinal (GI) bleeding due to angiodysplastic lesions is a common problem among patients receiving hemodialysis (HD). We studied 22 HD patients (5 females and 17 males) who had GI bleeding due to angiodysplasia; the mean age of whom was 54 ± 10 years. All patients had upper and lower GI endoscopy. The most common site for the lesion was the right colon in seven cases (31.8%), followed by stomach in 4 cases (18.1%). In eight (36.3%) patients, there were multiple lesions located in the stomach, duodenum, and the right colon. All patients were treated with coagulation; with argon plasma in 14 ...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Zajjari Y, Tamzaourte M, Montasser D, Hassani K, Aatif T, El Kabbaj D, Benyahia M Tags: Saudi J Kidney Dis Transpl Source Type: research

Incidence and mortality of acute kidney injury in patients with acute coronary syndrome: A retrospective study from a single coronary care unit.
Abstract Acute kidney injury (AKI) is associated with adverse short-and long-term outcomes. The aim of this study was to evaluate the incidence of AKI and the short-term mortality in patients admitted with acute coronary syndrome (ACS) to a single coronary care unit (CCU) in Tripoli, Libya. We retrospectively studied the medical records of ACS patients admitted to the CCU of a referral cardiology center, during the period from January 1, 2014, to December 31, 2014. AKI was defined according to the AKI network criteria. The incidence of AKI and short-term CCU mortality was compared between different types of ACS. D...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Buargub M, Elmokhtar ZO Tags: Saudi J Kidney Dis Transpl Source Type: research

Attitudes toward organ donation among personnel from the University Hospital of Rabat.
Abstract The medical staff could play a major role in promoting for organ donation. The aim of our study was to assess the attitudes of the medical staff toward organ donation. It is a prospective study conducted over a period of six months. A questionnaire was distributed and explained to the medical staff in our institute. Fifteen questions were designed to include four main themes: sociodemographic information, attitude toward organ donation, perceived knowledge about organ donation, and reasons for refusal or acceptance of organ donation. Among the 245 respondents, 36.3% had prior knowledge about organ transpl...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Flayou K, Kouam N, Miara H, Raoundi O, Ouzeddoun N, Benamar L, Bayahia R, Rhou H Tags: Saudi J Kidney Dis Transpl Source Type: research

Peritoneal dialysis and peritonitis rate: Kuwait, four years' experience.
Abstract Peritoneal dialysis (PD) program was established in Farwaniya Hospital Kidney Center, Kuwait, in February 2011. Patient recruitment for this modality of treatment was growing steadily. One of the major complications of PD is peritonitis. There is a belief that PD therapy is inferior and carries more complications than hemodialysis, we aimed to show that PD is a good and a non-inferior option for dialysis therapy with comparable outcome in both patient and technique survival. This was a retrospective analysis of all patients who were on PD from February 2011 to December 2014. Peritonitis rate, exit site in...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Alyousef AM, Abdou SM, Mansour YS, Radi AD Tags: Saudi J Kidney Dis Transpl Source Type: research

The knowledge, awareness, and acceptability of renal transplantation among patients with end-stage renal disease in Ibadan, Nigeria.
The objective of our study is to determine the knowledge, awareness, and acceptability of renal transplant among patients with end-stage renal disease (ESRD) and the factors which are responsible for the low level of transplantation in Ibadan, Nigeria. A 15-item pilot-tested questionnaire was administered to willing patients with ESRD seen at the medical outpatient clinic of the University Teaching Hospital, from January to December 2011. There was 81% participation rate of the respondents. Exactly 90.1% had formal education and 44% earned
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Takure AO, Jinadu YO, Adebayo SA, Shittu OB, Salako BL, Kadiri S Tags: Saudi J Kidney Dis Transpl Source Type: research

Comparison of total direct cost of conventional single use and mechanical reuse of dialyzers in patients of end-stage renal disease on maintenance hemodialysis: A single center study.
In this study, we compared the cost of mechanical reuse of dialyzer considering all of the direct costs (medications, dialyzer, and its consumables, disinfection fluid, and hospitalization if any) in HD treatment, which if significantly different between single use and reuse, can nullify the obvious cost benefits. A total of 70 adult patients of any gender on maintenance HD at The Kidney Centre Post Graduate Training Institute for more than three months were included. Equal numbers of patients were on single use (Group A) and reuse of dialyzer (Group B). Both groups were compared for total direct costs of HD over a six mon...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Qureshi R, Dhrolia MF, Nasir K, Imtiaz S, Ahmad A Tags: Saudi J Kidney Dis Transpl Source Type: research

Screening for kidney disease in an oil producing community in Nigeria: A pilot study.
Abstract Petroleum products have been associated with acute and chronic kidney disease. Nigeria is a major oil producing and exporting country. The aim of this study was to screen for kidney disease in an oil producing community in Nigeria. This was a cross-sectional study carried out in Ido, Asari-Toru Local Government Area of Rivers State. All subjects were resident in the town and those aged 18 years and above were eligible. Spot urine samples were collected for dipstick urinalysis, and venous blood was collected for estimation of serum electrolyte, urea, creatinine, and lipid profile. The estimated glomerular ...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Okafor UH, Ahmed S, Arigbodi O, Idogun S, Unuigbe EI Tags: Saudi J Kidney Dis Transpl Source Type: research

Metastatic neuroendocrine tumor of small cell type in a kidney transplant recipient.
We report a case of metastatic, small cell, neuroendocrine tumor in a post-renal transplant patient with progressive left inguinal nodes and right lumbar swellings. He had a remarkably elevated serum lactate dehydrogenase levels with multiple metastatic masses in the left inguinal, left iliac fossa, and right lower abdominal wall on abdominal computed tomography scan. Excisional biopsy of a left inguinal node revealed extensive infiltration with malignant cells in it. Immunohistochemistry staining was positive for synaptophysin, prostatic specific antigen, and CD56. While the primary small cell carcinoma of genitourinary o...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Mohd Kamil A, Draman CR, Seman MR, Kalavathy R, Mubarak MY Tags: Saudi J Kidney Dis Transpl Source Type: research

The first experience of sequential liver-kidney transplantation for the treatment of primary hyperoxaluria type-1 in Iran as a developing country.
Abstract Primary hyperoxaluria Type-1 (PH-1) is caused by a deficiency of alanine-glyoxylate aminotransferase manifesting as urolithiasis, nephrocalcinosis, and end-stage renal disease (ESRD). Among treatment options, best outcomes have been achieved by sequential liver-kidney transplantation (Seq-LKT). Herein, we report a patient with PH-1 and ESRD who underwent Seq-LKT in Iran. Criteria for diagnosis included a history of recurring calcium oxalate renal stones and elevated urine oxalate level combined with liver biopsy and absent enzymatic activity at the age of 13 years. Conservative treatment including pyridox...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Naderi G, Tabassomi F, Latif A, Ganji M Tags: Saudi J Kidney Dis Transpl Source Type: research

Hilar and para-aortic necrotizing lymphadenopathy associated with antineutrophil cytoplasmic antibody-negative pauci-immune crescentic glomerulonephritis.
We report a case of women with rapidly progressive renal disease associated with recurrent epigastric pain, weight loss, and massive hilar as well as para-aortic lymphadenopathy. Ultrasound-guided biopsy of her scarred kidneys revealed antineutrophil cytoplasmic antibody-negative crescentic glomerulonephritis and that of lymph nodes showed severe necrotizing vasculitis. Biopsy of the lymph nodes and the failing kidney established the diagnosis of this rare presentation and ruled out lymphoma and tuberculosis. Administration of corticosteroids and cyclophosphamide resulted in a favorable outcome. PMID: 27424701 [PubMed...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: El-Reshaid K, Varro J, Madda JP Tags: Saudi J Kidney Dis Transpl Source Type: research

Coexistence of atypical hemolytic uremic syndrome with membranoproliferative glomerulonephritis and antineutrophil cytoplasmic antibodies-associated vasculitis.
We describe two cases of renal failure with immune-mediated overlap conditions. We believe, this is the first reported case of antineutrophil cytoplasmic antibody (ANCA) associated vasculitis coexisting with atypical hemolytic uremic syndrome (HUS). Two boys aged eight years (Case 1) and 10 years (Case 2) presenting with renal failure secondary to glomerulonephritis are described. Based on the clinical features, a detailed immunological workup and kidney biopsy was performed to arrive at the diagnosis. Immune-mediated renal dysfunction was present in both cases. Screening for other coexisting autoimmune phenomenon was perf...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Sathe KP, Mehta KP Tags: Saudi J Kidney Dis Transpl Source Type: research

Fanconi syndrome due to light chain proximal tubulopathy in a patient with multiple myeloma.
Abstract Fanconi syndrome (FS) in an adult patient is an unusual finding and it merits thorough evaluation. Paraproteinemias are one of the common etiologies in adult FS and need to be ruled out. Among the various forms of renal involvement in multiple myeloma, light chain proximal tubulopathy (LCPT) is the rarest. Usually, it causes proximal tubular dysfunction which is characterized by intracytoplasmic deposition of crystallized, mostly kappa monoclonal light chains in proximal tubules; however, glomerular crystal deposition is unusual. Herein, we are presenting a patient with renal dysfunction and FS. On evalua...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Mathur M, Chacko B, Vankalakunti M, Patil C Tags: Saudi J Kidney Dis Transpl Source Type: research

Fanconi syndrome induced by tenofovir: A case report.
We describe a case of a patient infected with HIV, who presented with Fanconi syndrome with acute renal failure six months after starting antiretroviral treatment including tenofovir. PMID: 27424704 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Lify B, Dabo G, Nascimento O, Iraqui S, Elkhayat S, Zamd M, Medkouri G, Benghanem M, Ramdani B, Sodqi MM, Marih L, Chakib A, El FilaliMarhoum K Tags: Saudi J Kidney Dis Transpl Source Type: research

Successful treatment of proximal renal tubular acidosis and Fanconi syndrome with vitamin D replacement.
We present a case of a young female who presented with proximal RTA and Fanconi syndrome and excellently responded to Vitamin D replacement. Thus, work-up for the etiology of proximal RTA should include Vitamin D levels since replacement of this vitamin in those who are deficient can lead to cure of such patients. PMID: 27424705 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Ali SA, Tariq M Tags: Saudi J Kidney Dis Transpl Source Type: research

Minimal change disease: A case report of an unusual relationship.
We report a case of a 63-year-old male who presented with bilateral leg swelling due to nephrotic syndrome and acute kidney injury. A kidney biopsy showed minimal change disease with light chain deposition; however, no circulating light chains were present. This prompted a bone marrow biopsy, which showed chronic lymphocytic leukemia (CLL) with deposition of the same kappa monoclonal light chains. Three cycles of rituximab and methylprednisolone resulted in remission of both CLL and nephrotic syndrome, without recurrence during a three-year follow-up. PMID: 27424706 [PubMed - in process] (Source: Saudi Journal of Kidn...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Edrees F, Black RM, Leb L, Rennke H Tags: Saudi J Kidney Dis Transpl Source Type: research

Remarks about the study on mandibular mass in a child on hemodialysis.
PMID: 27424707 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Al-Mendalawi MD Tags: Saudi J Kidney Dis Transpl Source Type: research

Authors' reply.
MID: 27424708 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Authors' reply. Tags: Saudi J Kidney Dis Transpl Source Type: research

The onconephrology: Our experience in cancer patients.
PMID: 27424709 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Li Cavoli G, Rondello G, Li Cavoli TV, Rotolo U Tags: Saudi J Kidney Dis Transpl Source Type: research

An unusual case of idiopathic crescentic membranoproliferative glomerulonephritis with posterior reversible encephalopathy syndrome.
PMID: 27424710 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Yadla M, Sailaja S, Bottu M, Uppin M Tags: Saudi J Kidney Dis Transpl Source Type: research

Nephrotic syndrome related to immunoglobulin M nephropathy and hypothyroidism: An uncommon association.
PMID: 27424711 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Kaab BB, Bellakhal S, Souissi A, Mestiri A, Smida H, Douggui MH Tags: Saudi J Kidney Dis Transpl Source Type: research

Perigraft abscess with gas forming organism.
PMID: 27424712 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Pandya V, Sutariya H Tags: Saudi J Kidney Dis Transpl Source Type: research

Gitelman syndrome, familial seizures, and demyelinating neuropathy: Rare association may be due to sodium potassium cotransporter genes.
PMID: 27424713 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Singh RK, Bhoi SK, Kalita J, Misra UK Tags: Saudi J Kidney Dis Transpl Source Type: research

The relationship between inflammation, blood pressure, and mean platelet volume in chronic kidney disease.
PMID: 27424714 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Altun E, Paydas S, Kaya B, Seydaogulları G Tags: Saudi J Kidney Dis Transpl Source Type: research

Remarks about the study on causes of chronic kidney disease in Egyptian children.
PMID: 27424715 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Al-Mendalawi MD Tags: Saudi J Kidney Dis Transpl Source Type: research

Remarks about the study on lactate dehydrogenase as a biomarker for early renal damage in patients with sickle cell disease.
PMID: 27424716 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Al-Mendalawi MD Tags: Saudi J Kidney Dis Transpl Source Type: research

Authors' Reply.
MID: 27424717 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2016 Category: Urology & Nephrology Authors: Authors' Reply. Tags: Saudi J Kidney Dis Transpl Source Type: research

Hospital Contributing in Organ donation Program.
Authors: PMID: 27411239 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Tags: Saudi J Kidney Dis Transpl Source Type: research

C1q-binding anti-HLA antibody assay: A test dilemma.
Abstract Detection of donor-specific anti-HLA antibodies in patients with kidney graft, or awaiting kidney graft, acts as a predictor for antibody mediated rejection. Several methods are in practice for the detection of anti-HLA antibodies; including the latest introduction of C1q-binding anti-HLA antibody method. This method depends on detecting complement fixing anti-HLA antibodies on single antigen beads using C1q as the marker for the presence of those antibodies. Here we discuss recent data on this method and present a working hypothesis for explaining the inability of this method to detect low titer anti-HLA...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Hajeer AH Tags: Saudi J Kidney Dis Transpl Source Type: research

Is there an association between Vitamin D level and inflammatory markers in hemodialysis patients? A cross-sectional study.
Abstract Vitamin D deficiency is very prevalent among the patients with end-stage renal disease. The etiology of this is multifactorial, including nutritional deficiency, insufficient expo- sure to sunlight, race, obesity and not the least, impaired Vitamin D synthesis and metabolism in chronic kidney disease patients. We hypothesized that lower Vitamin D level will be associated with higher inflammatory burden and low immunological response to hepatitis B vaccination in hemodialysis (HD) population. The study was carried out in March 2013 among 100 HD patients who were identified to be eligible for the study. Thi...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Mohiuddin SA, Marie M, Ashraf M, Hussein M, Almalki N Tags: Saudi J Kidney Dis Transpl Source Type: research

Evaluation of continuous ambulatory peritoneal dialysis fluid C-reactive protein in patients with peritonitis.
Abstract Severe peritonitis causing death is one of the most devastating complications of peritoneal dialysis (PD). Since the predictive value of C-reactive protein (CRP) in PD fluid has not been assessed, the objective of the present study is to evaluate its predictive value and clinical correlation in patients on PD with peritonitis. One hundred and twenty patients on continuous ambulatory PD (CAPD) were enrolled and their serum and fluid CRP (Fl. CRP) were evaluated at the start of CAPD. All patients who developed peritonitis were further evaluated for serum and fluid CRP. The patients were categorized into fou...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Ramanathan K, Padmanabhan G, Vijayaraghavan B Tags: Saudi J Kidney Dis Transpl Source Type: research

The association between glycemic control and microalbuminuria in Type 2 diabetes.
Abstract Microalbuminuria is an independent risk factor for cardiovascular and renal out- come in a patient with Type 2 diabetes. The evidence that intensive glycemic control reduces the microvascular complications of diabetes is based almost exclusively on prevention of micro- albuminuria. To evaluate the association between microalbuminuria and glycemic control and other factors in Type 2 diabetes, we studied retrospectively 551 patients with Type 2 diabetes. The patients were divided into two groups: 175 patients with microalbuminuria in the case group and 376 with normal urine albumin-creatinine ratio in the c...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Showail AA, Ghoraba M Tags: Saudi J Kidney Dis Transpl Source Type: research

Renal impairment in multiple myeloma: A single center experience.
Abstract To determine the features of the different forms of kidney diseases associated with multiple myeloma (MM), we retrospectively studied 144 patients with kidney injury and MM at our institute from 1974 to 2014. The mean age of the patients was 60.1 years and the male:female ratio was 1.25. Renal disease was concomitant with the discovery of MM in 92% of cases. The mean follow-up of our patients was 2.1 years. Initial renal insufficiency was found in 131 (91%) patients. Cast nephropathy of the distal tubule was found in 110 (26%) patients, renal amyloidosis in 16 (11.1%), and light chain deposition disease i...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Gorsane I, Barbouch S, Mayara M, Abdelghani KB, Goucha R, Hamida FB, Hedri H, Abdallah TB Tags: Saudi J Kidney Dis Transpl Source Type: research

The effect of phototherapy on urinary calcium excretion in term neonates.
Abstract Phototherapy is the most common, most effective, and least dangerous treatment method for neonatal hyperbilirubinemia and is the treatment of the first choice for neonatal icterus. Hypocalcemia is one of the lesser-known complications of phototherapy. Some studies have shown a relationship between increased urinary calcium excretion and phototherapy-induced hypocalcemia. We aimed to assess the effect of phototherapy on urinary calcium excretion in term neonates. This before-after study was performed on 80 term neonates having hyper- bilirubinemia referred to the 17thShahrivar Hospital, Rasht, Guilan Provi...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Asl AS, Zarkeshl M, Heidarzadeh A, Maleknejad S, Hagikhani K Tags: Saudi J Kidney Dis Transpl Source Type: research

Contribution of glomerular morphometry to the diagnosis of pediatric nephropathies.
This study was conducted to identify an association between morphometric data in renal biopsies and renal function of these patients. Fifty-nine individuals with ages between 2 and 18 years old were selected, who were divided into six groups consisting of frequent nephropathies in children and adolescents and one control group. Proteinuria, urea, and creatinine values of the patients were recorded. Interactive image analysis software Leica QWin[®]was used for morpho- metric analysis of Bowman's capsule, glomerular capillary tuft, and Bowman's space area. The mean glomerular tuft area was higher in the membranous glomer...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Marini MB, Rocha LP, Machado JR, Ramalho FS, Dos Reis MA, Corrêa RR Tags: Saudi J Kidney Dis Transpl Source Type: research

Prevalence of asymptomatic urinary abnormalities among adolescents.
Abstract To determine the prevalence of asymptomatic urinary abnormalities in adolescents, first morning clean mid-stream urine specimens were obtained from 2500 individuals and examined by dipstick and light microscopy. Adolescents with abnormal screening results were reexamined after two weeks and those who had abnormal results twice were subjected to systemic clinical examination and further clinical and laboratory investigations. Eight hundred and three (32.1%) individuals had urinary abnormalities at the first screening, which significantly decreased to 345 (13.8%) at the second screening, (P
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Fouad M, Boraie M Tags: Saudi J Kidney Dis Transpl Source Type: research

Neurological and cardiac complications in a cohort of children with end-stage renal disease.
Abstract Adult patients with chronic kidney disease are at risk of major neurologic and cardiac complications. The purpose of this study is to review the neurological and cardiac complications in children with end-stage renal disease (ESRD). A retrospective review of medical records of children with ESRD at Jordan University Hospital was performed. All neurological and cardiac events were recorded and analyzed. Data of a total of 68 children with ESRD presenting between 2002 and 2013 were reviewed. Neurological complications occurred in 32.4%; seizures were the most common event. Uncontrolled hypertension was the ...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Albaramki JH, Al-Ammouri IA, Akl KF Tags: Saudi J Kidney Dis Transpl Source Type: research

The effects of dual and triple combinations of trandolapril, telmisartan, and verapamil on overt proteinuria in the patients with diabetic nephropathy.
In this study, the effects of double and triple combinations of trandolapril, telmisartan, and verapamil on proteinuria were investigated in diabetic patients with nephropathy. Seventy-eight patients (mean age: 56.11 ± 11.26 years; 47 females and 31 males) with overt proteinuria and DN were included in this study. The patients were divided into four groups: Group I (n: 18, trandolapril + telmisartan), Group II (n: 20, trando- lapril + verapamil), Group III (n: 20, trandolapril +telmisartan + verapamil), and Group IV (n: 20, telmisartan + verapamil). At the end of a three-month therapy, within and between group compa...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Albayrak B, Cankaya E, Cetinkaya R, Cerrah S, Bilen Y Tags: Saudi J Kidney Dis Transpl Source Type: research

Na/K citrate versus sodium bicarbonate in prevention of contrast-induced nephropathy.
Abstract Contrast-induced nephropathy (CIN) is one of the important complications of radiographic procedures, especially in patients with chronic kidney disease. It is also one of the common causes of acute kidney injury. The pathogenesis is postulated to be the effect of oxygen- free radicals and hyperosmolar stress on the renal medulla. It is reported that the production of superoxide is most active at acid environment. K/Na citrate is well known as a urine alkalini- zation medium, and this has been evaluated earlier with standard hydration for reduction of CIN and was stated to be efficient. We aimed to determi...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 1, 2016 Category: Urology & Nephrology Authors: Abouzeid SM, ElHossary HE Tags: Saudi J Kidney Dis Transpl Source Type: research