An unusual cause of anuria in a young patient with hypertension.
PMID: 29265069 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2017 Category: Urology & Nephrology Authors: Yadla M, Khandalvelli P, Uppin M Tags: Saudi J Kidney Dis Transpl Source Type: research

Milk-alkali syndrome and influenza vaccination.
PMID: 29265070 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2017 Category: Urology & Nephrology Authors: Yasri S, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

The story of the first deceased donor kidney donation in Saudi Arabia - by a firsthand witness.
PMID: 28937053 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Al-Sayyari AA Tags: Saudi J Kidney Dis Transpl Source Type: research

The importance of bone biopsy in chronic kidney disease-Mineral bone disorders.
Abstract Renal osteodystrophy (ROD) is not a uniform bone disease; it is a heterogeneous group of metabolic bone diseases due to chronic kidney disease (CKD). The traditional term of ROD does not accurately include the wide spectrum of "CKD-mineral and bone disorder" (CKD-MBD) and has been restricted to define the several specific histologic disturbances of bone disease associated with CKD. Circulating parathyroid hormone (PTH) and total alkaline phosphatase levels do not always reflect bone turnover in CKD-MBD, whereas bone biopsy provides precise information regarding bone pathology. Given the lack of ...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Dousdampanis P, Trigka K Tags: Saudi J Kidney Dis Transpl Source Type: research

Association between apolipoprotein E polymorphism and nephropathy in Iranian diabetic patients.
Abstract Approximately one-third of diabetic patients develop evidence of nephropathy. Pathogenesis of diabetic nephropathy (DN) remains unclear; however, some genetic and metabolic risk factors have been determined for the development and progression of DN. In the recent genetic studies, polymorphism of apolipoprotein E (ApoE) gene has been reported as a risk factor for the development of DN; however, the results are inconsistent. The aim of the present study was to evaluate the association between ApoE polymorphism and nephropathy in Iranian patient with type 2 diabetes. A total of 197 patients with type 2 diabe...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Karimoei M, Pasalar P, Mehrabzadeh M, Daneshpour M, Shojaee M, Forouzanfar K, Razi F Tags: Saudi J Kidney Dis Transpl Source Type: research

Serum cystatin C as an earlier predictor of acute kidney injury than serum creatinine in preterm neonates with respiratory distress syndrome.
In this study, we aimed to evaluate serum cystatin C (sCysC) as an early predictor of acute kidney injury (AKI) in preterm neonates with respiratory distress syndrome (RDS). Sixty preterm neonates diagnosed with RDS and 40 healthy controls (28-36 weeks) admitted to the neonatal Intensive Care Unit were investigated. AKI was defined on the 3rd day of life (DOL-3) as an increase in serum creatinine (sCr) of>0.3 mg/dL from baseline (the lowest previous sCr). sCysC levels were measured on DOL-1, -3 and -7. Of the 60 neonates with RDS, 24 (40%) developed AKI. Five patients (79.17%) were classified as AKI Network (AKIN-1) and...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Abdelaal NA, Shalaby SA, Khashana AK, Abdelwahab AM Tags: Saudi J Kidney Dis Transpl Source Type: research

Outcome of childhood lupus nephritis in Saudi children.
Abstract Our aim in this study is to report the long-term renal outcome of a cohort of Saudi children with systemic lupus erythematosus (SLE). All patients with childhood lupus nephritis (cLN) proved by renal biopsy seen between January 2000 and June 2015 were reviewed. The renal outcome was assessed according to serum creatinine level, protein/creatinine ratio at the last follow-up visit, and/or evidence of renal impairment during follow-up period and end-stage renal disease (ESRD). Additional outcome measures include accrual damage measured by pediatric adaptation of the Systemic Lupus International Collaboratin...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Al-Mayouf SM, AlAmeer A, Alfattani A, Alsonbul A Tags: Saudi J Kidney Dis Transpl Source Type: research

Epidemiology of human leukocyte antigens among omani population.
This study showed considerable heterogeneity in both HLA Class I and Class II antigens, which reflects admixture of our population with rest of old world countries. Despite the high levels of consanguinity, this population is genetically highly heterogeneous. These findings may be useful for transplantation programs, noncommunicable diseases, epidemiology of HLA linked diseases, pharmacogenomics, and anthropology. PMID: 28937058 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Al Salmi I, Metry AM, Al Ismaili F, Hola A, Shaheen F, Fakhoury H, Hannawi S Tags: Saudi J Kidney Dis Transpl Source Type: research

The effect of an educational program for vascular access care on nurses' knowledge at dialysis centers in Khartoum State, Sudan.
This study was to evaluate the effect of an educational program for vascular access care on nurses' knowledge at nine dialysis centers in Khartoum State. This was a Quasi experimental study (pre-and post-test for the same group). Sixty-one nurses working in these HD centers were chosen by simple random sampling method. A structured face-to-face interview questionnaire based on the Kidney Dialysis Outcome Quality Initiative (K/DOQI) clinical practice guidelines for vascular access care was used. Instrument validity was determined through content validity by a panel of experts. Reliability of the instrument was tested by a p...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Yousif KI, Abu-Aisha H, Abboud OI Tags: Saudi J Kidney Dis Transpl Source Type: research

Repercussions of eosinophils in a renal allograft - Predictor of early graft loss!
In conclusion, the presence of eosino-phils in a renal allograft is an impending sign of graft damage and eventual graft loss. PMID: 28937060 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Vanikar AV, Kanodia KV, Patel RD, Suthar KS, Nigam LA, Thakkar UG, Patel HV, Kute VB, Trivedi HL Tags: Saudi J Kidney Dis Transpl Source Type: research

Long-term evaluation of kidney function in live-related kidney donors.
Abstract The consequences of live kidney donation on the donor health with main emphasis on postdonation blood pressure (BP), proteinuria, kidney size, and glomerular filtration rate (GFR) were evaluated. Twenty-five donors with minimum of six months postdonation duration were included in the study. Donor age at nephrectomy, duration postnephrectomy, systolic and diastolic BP measurement pre-and post-donation, postdonation, blood urea nitrogen, serum creatinine and 24-h proteinuria, blood sugar, two-dimensional echocardiogram were recorded. Kidney sizes pre-and post-donation were noted. GFR was calculated by chron...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Mehta KS, Swami R, Pajai A, Bhurke S, Shirkande A, Jawle S Tags: Saudi J Kidney Dis Transpl Source Type: research

Cryotherapy intervention in relieving arteriovenous fistula cannulation-related pain among hemodialysis patients at the King Khalid Hospital, Tabuk, Kingdom of Saudi Arabia.
This study was performed to determine the effect of cryotherapy on reducing pain during AVF cannulation among HD patients in the King Khalid Hospital, Tabuk, Kingdom of Saudi Arabia. This is an experimental study which included 62 patients undergoing HD through an AVF. Randomization was used to assign the patients into the experimental (received cryotherapy) and control (no cryotherapy) groups. The Arabic version of Wong-Baker pain rating scale was used to determine the pain score. There was a significant difference in the pre-and post-intervention pain scores among the experimental group, while there was no such differenc...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Al Amer HS, Dator WL, Abunab HY, Mari M Tags: Saudi J Kidney Dis Transpl Source Type: research

A "Mini-Epidemic" of anti-glomerular basement membrane disease: Clinical and epidemiological study.
A "Mini-Epidemic" of anti-glomerular basement membrane disease: Clinical and epidemiological study. Saudi J Kidney Dis Transpl. 2017 Sep-Oct;28(5):1057-1063 Authors: Lingaraj U, Mallappa SS, Neminah RE, Mohan SM, Venkatesh L, Gurusiddaiah SC, Rachaiah NM Abstract Acute glomerulonephritis due to anti-glomerular basement membrane (anti-GBM) antibody disease is rare, estimated to occur in fewer than one case per million population and accounts for less than 20% of rapidly progressive glomerulonephritis. The prevalence among patients evaluated for potential glomerular disease is lower. It accoun...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Lingaraj U, Mallappa SS, Neminah RE, Mohan SM, Venkatesh L, Gurusiddaiah SC, Rachaiah NM Tags: Saudi J Kidney Dis Transpl Source Type: research

Nephrocalcinosis among children at king hussein medical center: Causes and outcome.
This study illustrated the need for a national registry of rare renal diseases to help understand the causes of these conditions in our populations and provide support to affected patients and their families. PMID: 28937064 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Al-Bderat JT, Mardinie RI, Salaita GM, Al-Bderat AT, Farrah MK Tags: Saudi J Kidney Dis Transpl Source Type: research

Mycophenolate mofetil or cyclophosphamide in indian patients with lupus nephritis: Which is better? A single-center experience.
Abstract Mycophenolate mofetil (MMF) is used extensively for the induction therapy of lupus nephritis (LN) and has even outpaced intravenous (i.v.) cyclophosphamide (CyP) as the initial choice of therapy. There are no studies comparing the response of MMF with standard dose i.v. CyP in Indian patients with LN. We conducted a 24-week prospective, randomized, open-label trial comparing oral MMF with monthly i.v. CyP as induction therapy for active biopsy proven Class III and IV LN. The primary end-point was response to treatment at 24 weeks, and the secondary end-points were complete remission, Systemic Lupus Erythe...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Mendonca S, Gupta D, Ali S, Gupta P Tags: Saudi J Kidney Dis Transpl Source Type: research

Relationship of insulin resistance to vitamin d status in children with nondiabetic chronic kidney disease.
This study aimed to investigate the association of IR and 25-hydroxyvitamin D levels. In this study, we evaluated the frequency of IR in predialysis patients and the association with 25-hydroxyvitamin (OH)D levels. A total of 32 non-diabetic patients with predialysis were included in the study. Homeostasis model assessment for insulin resistance (HOMA-IR) index was calculated to show presence of IR. Data were analyzed with the Statistical Package for the Social Sciences (SPSS) program version 13.0 (SPSS Inc, Chicago, Ill, USA) using the Chi-square, Student t-test, and logistic regression analysis. Nineteen of 32 subjects (...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Conkar S, Mir S Tags: Saudi J Kidney Dis Transpl Source Type: research

Histopathological patterns of renal diseases in egyptian children: A single-center experience.
Abstract The present cross-sectional, retrospective study was aimed to determine the histopathological spectrum of renal diseases in Egyptian children and to evaluate the indications, safety, and efficacy of percutaneous renal biopsy (PRB) in a large tertiary center in Egypt. PRBs performed at the Department of Pediatrics, Tanta University Hospital over a period of nine years (from January 2007 to December 2015) were included. Light microscopic (LM) examination was performed in all cases while immunofluorescence and electron microscopic examination were performed in selected cases. Two hundred and thirty renal bio...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Abdel-Hafez MA, Abdel-Nabi H, El-Gamasy M, Zayton H, Nassar I Tags: Saudi J Kidney Dis Transpl Source Type: research

Knowledge of acute kidney injury among nurses in two government hospitals in Ondo City, Southwest Nigeria.
This study determined the knowledge of AKI among nurses in two government hospitals in Ondo City, Southwest Nigeria. This cross-sectional descriptive study was carried out in two government hospitals in Ondo City using a self-administered pretested questionnaire that assessed knowledge of AKI and associated factors. A total of 156 respondents participated in the study. Majority were between 20 and 40 years of age and were females. Ninety-nine (63.5%) had ≤10 years of nursing experience. A total of 106 (67.5%) respondents had received formal lectures on AKI in the past. Only 12 (7.7%) respondents had good knowledge of AK...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Adejumo OA, Akinbodewa AA, Alli OE, Pirisola OB, Abolarin OS Tags: Saudi J Kidney Dis Transpl Source Type: research

Oral health in diabetic and nondiabetic patients with chronic kidney disease.
The objective of our study is to assess the subjective and objective oral manifestations and salivary pH in diabetic and nondiabetic uremic patients at a nephrology clinic. A total of 194 diabetic and nondiabetic patients with chronic kidney disease (CKD), who were divided into four groups, Group A, B, C, D, and who were attending a nephrology clinic were included in the study. Predialytic unstimulated whole salivary pH was recorded using pH- measuring strips. Subjective and objective findings were evaluated and recorded in the specially designed pro forma. Dental health assessment consisted of decayed, missing, and filled...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Swapna LA, Koppolu P, Prince J Tags: Saudi J Kidney Dis Transpl Source Type: research

Renal transplantation in HIV-positive patients - No more a scare!
Abstract Human immunodeficiency virus (HIV) infection has posed as a major global health epidemic for almost three decades. With the advent of highly active antiretroviral therapy in 1996 and the application of prophylaxis and management of opportunistic infections, acquired immunodeficiency syndrome mortality has decreased markedly. The most aggressive HIV-related renal disease is end-stage renal disease due to HIV-associated nephropathy. Presence of HIV infection used to be viewed as a contraindication to renal transplantation for multiple reasons; concerns for exacerbation of an already immunocompromised state ...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Mahesh E, John MM, Konana GC, Parampalli RM, Bande SR, Suryadevara S Tags: Saudi J Kidney Dis Transpl Source Type: research

Insomnia in hemodialysis patients: A multicenter study from morocco.
This study aims to determine the prevalence and risk factors of insomnia in our chronic hemodialysis (HD) patients. This is a cross-sectional study conducted in three HD units in Morocco. To assess the prevalence of insomnia, we used a specific questionnaire. Patients complaining of difficulty in falling asleep and/or nocturnal awakenings occurring seven nights a week during the last month were included in the group "insomnia;" the other patients were used as controls. Clinical, biological, and dialysis data were recorded for each patient. Sleep disorders and their subjective causes were also identified. Eighty-n...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Hamzi MA, Hassani K, Asseraji M, El Kabbaj D Tags: Saudi J Kidney Dis Transpl Source Type: research

Epidemiology of end-stage renal disease in Dubai: Single-center data.
This report represents the demographic data and clinical characteristics of our HD patients during the period between January 2012 and October 2016. Diabetic nephropathy (57%) and hypertension (12.4%) are emerging as the most common causes of end-stage renal disease (ESRD) in our data, followed by undetermined causes in those who presented as ESRD (10.9%), and then by rejected transplant in 4.6%. Obstructive uropathy in our data was 4.37% among all causes. The causes were primary glomerulonephritis (only proven cases in kidney biopsy were counted) in 3.6%, adult polycystic kidney disease in 2.43%, and lupus nephritis in 1....
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Alalawi F, Ahmed M, AlNour H, Noralla M, Alhadari A Tags: Saudi J Kidney Dis Transpl Source Type: research

Hepatitis C virus status in hemodialysis patients in Menoufia Government, Egypt, five years apart: Do we have any improvement?
Abstract There is a high prevalence of hepatitis C virus (HCV) infection in hemodialysis (HD) patients in Menoufia Governorate, Egypt. The aim of this cross-sectional study was to assess current HCV status and its seroconversion in HD patients after implementing preventative measures to limit transmission of HCV. All data were compared with our previous data collected in 2011 before implementation of isolation policy. There was a significant decrease in HCV infection in HD patients from 49.6% in year 2011 to 41.9% in year 2016 (P = 0.001). The seroconversion rate was significantly reduced from 14.5% in year 2011 t...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Amin Elzorkany KM, Zahran A Tags: Saudi J Kidney Dis Transpl Source Type: research

Clinicoepidemiological profile of peritonitis complicating acute peritoneal dialysis: A single-center experience.
Abstract A prospective observational study examining the incidence and microbiological aspects of peritonitis complicating acute intermittent peritoneal dialysis (IPD) was performed. A total of 145 acute IPD treatments were included involving 112 patients. The majority of patients suffered from acute kidney injury (72.3%) secondary to sepsis. Peritonitis occurred in 31 treatment sessions, giving a frequency of 21.4% of procedures performed. The mean interval between starting dialysis and the first sign of peritonitis was 2.9 days, with 58% of cases occurring in the Intensive Care Unit. Frequent catheter manipulati...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Gandhi K, Prasad D, Malhotra V, Agrawal D, Beniwal P, Leon Dsouza AV Tags: Saudi J Kidney Dis Transpl Source Type: research

A comparison of socioeconomic level among hemodialysis patients and normal controls in the fars province, Iran.
Abstract Chronic kidney disease (CKD) is a public health problem and it is suggested that low socioeconomic status (SES) may increase the risk of renal failure. The aim of this study was to report and compare the SES of hemodialysis patients (HD) and normal population in Shiraz, Iran. In this cross-sectional study, we evaluated 519 HD patients and 900 normal controls. We asked about SES using a questionnaire. The participants were categorized into three groups according to their SES as low, medium, and high SES. Of the 1419 participants, 454 (31.7%), 581 (40.6%), and 395 (27.6%) were grouped in low, medium, and hi...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Malekmakan L, Pakfetrat M, Daneshian A, Sayadi M Tags: Saudi J Kidney Dis Transpl Source Type: research

Prevalence and risk factors of chronic kidney disease in newly diagnosed and untreated hypertensive patients in cameroon: A cross-sectional study.
Abstract Chronic kidney disease (CKD) has emerged as a worldwide problem and is a major cause for comorbidity in hypertensive patients. In an attempt to enhance awareness and to help in establishing preventive measures and care, it is necessary to describe CKD among newly diagnosed and untreated hypertensive patients. We conducted a cross-sectional study to describe the characteristics of CKD among newly diagnosed, treatment naïve, hypertensive patients in four health-care centers in the city of Douala, Cameroon. Sociodemographic and biological data were collected and serum creatinine was measured by enzymati...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Kamdem F, Lekpa FK, Doualla MS, Nouga YN, Sontsa OD, Temfack E, Kingue S Tags: Saudi J Kidney Dis Transpl Source Type: research

Practice pattern of hemodialysis among end-stage renal disease patients in Rural South India: A single-center experience.
Abstract Hemodialysis (HD) is the most common mode of renal replacement therapy for end-stage renal disease (ESRD) patients in India. However, the practice and pattern of dialysis in a hospital serving rural population is largely unknown. A prospective study of 127 ESRD patients initiated on HD between January 2013 and December 2014 was done. The study included 101 males and 26 females, with a mean age of 50.05 ± 13.80 years. Native kidney disease was unknown in 45.67% of patients as they presented very late in their disease course. Nearly 87.4% of patients had emergency dialysis. Only 6.30% of patients had...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Hemachandar R Tags: Saudi J Kidney Dis Transpl Source Type: research

Acute kidney injury with granulomatous interstitial nephritis and vasculitis revealing sarcoidosis.
We report a case who presented an acute kidney failure and had sarcoidosis with vasculitis and nodular splenic involvement. A 35-year-old woman presenting a Lofgren syndrome was hospitalized for acute renal failure with cervical lymphadenopathy without other clinical findings. Laboratory data disclosed elevated angiotensin converting enzyme serum level. Abdominal ultrasound showed a multinodular spleen. Renal histology revealed granulomatous interstitial nephritis with necrotizing vasculitis. Outcome was favorable after the institution of high dose corticosteroids along with cyclophosphamide. Renal involvement is rare in s...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Harzallah A, Kaaroud H, Boubaker K, Barbouch S, Goucha R, Hamida FB, Abdallah TB Tags: Saudi J Kidney Dis Transpl Source Type: research

Neonatal bartter syndrome in an extremely low birth weight baby.
Abstract Early diagnosis of Bartter syndrome (BS) in the neonatal period is a clinical challenge, more so in an extremely low birth weight (ELBW) baby because of the inherent renal immaturity and the associated difficulty in fluid management. However, once a diagnosis is made, the disorder is known to respond well to fluid and electrolyte management, prostaglandin inhibitors, and potassium-sparing diuretics. Herein, we report a case of neonatal BS in a very premature ELBW infant. PMID: 28937079 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Hegde D, Mondkar J, Abdagire N Tags: Saudi J Kidney Dis Transpl Source Type: research

Branchio-oto-renal syndrome presenting with syndrome of hyporeninemic hypoaldosteronism.
We report the case of a 10-year-old boy with BOR syndrome who presented with hyperkalemic hyperchloremic metabolic acidosis due to hyporeninemic hypoaldosteronism. The child also had mental retardation and spastic diplegia which have hitherto not been described in BOR syndrome. PMID: 28937080 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: David JJ, Shanbag P Tags: Saudi J Kidney Dis Transpl Source Type: research

Direct-acting antiviral drugs against hepatitis C virus in renal transplant recipients: Is it the dawn of an interferon-free Era?
Abstract Hepatitis C virus (HCV) is a significant problem among hemodialysis population, especially in India where renal transplant often gets delayed in the presence of live-related donors. An acceleration of liver cirrhosis and poor renal allograft outcomes are often witnessed in allograft recipients with high viral load. Use of interferon in the postrenal transplant setting for the treatment of hepatitis C viral infection was limited to a few grave situations, fearing the precipitation of allograft rejection and poor efficacy for sustained virological remission. However, the availability of newer direct-acting ...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Rangaswamy D, Nagaraju SP, Attur RP Tags: Saudi J Kidney Dis Transpl Source Type: research

Treatment of steroid-resistant focal segmental glomerulosclerosis with rituximab: A case report and review of literature.
We report on the case of a 76-year-old male with steroid-resistant FSGS successfully treated with rituximab and remained in remission at the end of six months. A review of the literature highlights the paucity of data on this subject. We conclude that rituximab is a potentially useful treatment for steroid resistant FSGS and larger controlled studies are needed to further define its role in this setting. PMID: 28937082 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Varwani MH, Sokwala A Tags: Saudi J Kidney Dis Transpl Source Type: research

Infantile cystinosis: From dialysis to renal transplantation.
In this report, we present the first case of transplanted nephropathic cystinosis in a Tunisian child. A 4-year-old Tunisian boy born to nonconsanguineous parents, was treated in our medical services in 1990 for cystinosis. Since the age of five months, he developed symptoms of severe weight loss, vomiting, dehydration, and polyuria. He manifested the Toni Debré Fanconi syndrome. Slit lamp examination of the anterior segment of both eyes revealed fine, shiny crystal-like deposits diffusely distributed in the corneal epithelium and the stroma. Our patient had renal failure. At the age of seven, he reached terminal ch...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Jellouli M, Ferjani M, Abidi K, Zarrouk C, Abdelmoula J, Gargah T Tags: Saudi J Kidney Dis Transpl Source Type: research

Primary Sj ögren's syndrome complicated by anti-neutrophil cytoplasmic antibody-mediated crescentic glomerulonephritis.
We report three clinical cases of SS with anti-neutrophil cytoplasmic antibody-mediated crescentic glomerulo-nephritis treated with prednisone and cyclophosphamide, with favorable outcome. PMID: 28937084 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Ghorbel IB, Belfeki N, Salem TB, Houman MH Tags: Saudi J Kidney Dis Transpl Source Type: research

Galloway-mowat syndrome - unusual form of nephrotic syndrome in adolescent.
Abstract Galloway-Mowat syndrome (GMS), also acknowledged as Microcephaly-Hiatal hernia nephrotic syndrome, is an uncommon genetic disorder inherited as an autosomal recessive trait usually seen before two years of life. It is an exceptional multisystem genetic disorder with a collection of skeletal, neurological, facial, gastrointestinal, growth, and renal abnormalities. This case report describes GMS in a girl, suffering from developmental delay, stunted growth, and various dysmorphic features, in whom nephrotic syndrome became apparent at adolescent age. PMID: 28937085 [PubMed - in process] (Source: Saudi ...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Naidu GD, Deepthi P, RajaKarthik K, Sriram S, Swarnalatha G, Gangadhar T Tags: Saudi J Kidney Dis Transpl Source Type: research

Pulmonary thromboembolism as first presentation of childhood membranous nephropathy.
Abstract Nephrotic syndrome is associated with an increased risk of thromboembolism. Pulmonary thromboembolism has been described in nephrotic syndrome with or without deep vein thrombosis. In this case report, we describe an unusual first presentation of childhood membranous nephropathy with massive pulmonary thrombus with pulmonary infarction with right renal vein thrombosis. PMID: 28937086 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Madken M, Nagaraju SP, Attur RP, Vankalakunti M Tags: Saudi J Kidney Dis Transpl Source Type: research

Urinary interleukin-10 in renal transplant recipients: Does it predict a state of tolerance or rejection.
PMID: 28937087 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Elnokeety MM, Shaker AM, Fayed AM Tags: Saudi J Kidney Dis Transpl Source Type: research

Mild renal pyelectasis: A practical and simple approach in neonate and infant.
PMID: 28937088 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Malaki M Tags: Saudi J Kidney Dis Transpl Source Type: research

Usefulness of organoid technology and kidney transplantation.
PMID: 28937089 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Renal failure due to important arbovirus infection: A short summary.
PMID: 28937090 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Wiwanitkit S, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Toxicity of star fruit (Averrhoa carambola) in renal patients: A systematic review of the literature.
Abstract Several reports have discussed the neurotoxic effects of star fruit (Averrhoa carambola) in patients with chronic kidney disease (CKD). There is also some evidence highlighting the potentially harmful effects on patients with apparently normal renal function, who after consuming this fruit, developed acute renal injury. We performed a systematic review of the literature in the two main global databases (PubMed and Embase) as well as in Lilacs, for Latin American publications. We also included case reports, case series, or review articles which presented individual patient data. Animal or in vitro studies ...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2017 Category: Urology & Nephrology Authors: Aranguren C, Vergara C, Rosselli D Tags: Saudi J Kidney Dis Transpl Source Type: research

Assessment of frailty in elderly pre-dialysis population using simple tools.
Abstract Prevalence of chronic kidney disease (CKD) is increasing worldwide principally among the elderly population many of whom will eventually need renal replacement therapy. The relationship between frailty and CKD in the elderly population has been recognized. However, studies concentrating on frailty in pre-dialysis patients are limited. CKD predisposes to frailty through many potential mechanisms; anemia, bone mineral disease, oxidative stress, and malnutrition which in turn lead to progression of CKD culminating in a vicious cycle. Identifying potential causes of frailty in elderly pre-dialysis patients an...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2017 Category: Urology & Nephrology Authors: Ali H, Abdelaal F, Baharani J Tags: Saudi J Kidney Dis Transpl Source Type: research

Apoptosis of rat renal cells by organophosphate pesticide, quinalphos: Ultrastructural study.
Abstract Quinalphos or Ekalux, an organophosphate pesticide, is used in controlling the pests of a variety of crops. Quinalphos was studied on male Sprague-Dawley albino rats. The acute po LD50 of technical Ekalux was 19.95 mg/kg in males. Ekalux, produced several pathological changes in the kidney. A glomerulus demonstrated capillary lumina occluded by degenerated cellular debris. Basement membrane showed irregular wrinkling and branching. The proximal tubular cells showed damage such as dilation of endoplasmic reticulum, accumulation of glycogen granules, and pyknotic nucleus. The changes also included swelling ...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2017 Category: Urology & Nephrology Authors: Eid RA Tags: Saudi J Kidney Dis Transpl Source Type: research

Variables affecting darbepoetin resistance index in hemodialysis patients.
Abstract Erythropoietin resistance index calculation has been used as a tool to evaluate anemia response to erythropoietin therapy. Very little has been reported in its use when using darbepoetin and factors influencing in Arab patients. Darbepoetin resistance index (DRI) was calculated in all our patients using darbepoetin. This was correlated to demographic, clinical, and laboratory parameters. Of the 250 patients, 40.4% were diabetic, 71.1% on hemodialysis, and 28.6% on hemodiafiltration), 23.9% with PermCaths (PC), and 76.1 % with arteriovenous fistula (AVF). The mean DRI was 10.96 ± 12.9 I. Females had...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2017 Category: Urology & Nephrology Authors: Hejaili F, Hafeez E, Bhutto B, Al Turki L, Alsuwida AK, Raza H, Al-Sayyari A Tags: Saudi J Kidney Dis Transpl Source Type: research

A comparative study to evaluate factors that influence survival in multidisciplinary predialysis educated patients and "Crashlanders".
A comparative study to evaluate factors that influence survival in multidisciplinary predialysis educated patients and "Crashlanders". Saudi J Kidney Dis Transpl. 2017 Jul-Aug;28(4):743-750 Authors: Zukmin K, Ahmad I, Wynn AK, Lim YY, Naing L, Chong VH, Khalil MAM, Tan J Abstract Integrated multidisciplinary predialysis education (MPE) is usually provided to support and prepare the pre-end-stage renal disease (ESRD) patients before the initiation of renal replacement therapy (RRT). However, the impact of MPE is not known in our population, which is comprised patients of Asian origins and rec...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2017 Category: Urology & Nephrology Authors: Zukmin K, Ahmad I, Wynn AK, Lim YY, Naing L, Chong VH, Khalil MAM, Tan J Tags: Saudi J Kidney Dis Transpl Source Type: research

End-stage renal disease in patients with sickle cell disease.
In conclusion, most patients with SCD who developed ESRD were resistant to ESA and required repeated blood transfusion. The rate of hospitalization due to pain crisis was relatively low. Survival on dialysis was comparable to that of patients with no SCD, and the post-transplant course was relatively benign. PMID: 28748876 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2017 Category: Urology & Nephrology Authors: Alkhunaizi AM, Al-Khatti AA, Al-Mueilo SH, Amir A, Yousif B Tags: Saudi J Kidney Dis Transpl Source Type: research

Vitamin D levels and other biochemical parameters of mineral bone disorders and their association with diastolic dysfunction and left ventricular mass in young nondiabetic adult patients with chronic kidney disease.
Abstract Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with end-stage renal disease. Chronic kidney disease (CKD)-associated cardiovascular mortality is more prevalent in those with diastolic heart failure and is an early predictor, while increased left ventricular mass (LVM) is a strong independent risk factor. Hypovitaminosis D is extensively being studied as a nontraditional risk factor for CVD. The aim of the present study is to look at the association of Vitamin D and other parameters of mineral bone disorder (MBD) with diastolic dysfunction and LVM in nondiabetic yo...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2017 Category: Urology & Nephrology Authors: Sonkar SK, Bhutani M, Sonkar GK, Pandey SK, Chandra S, Bhosale V Tags: Saudi J Kidney Dis Transpl Source Type: research

Assessment of hepatic fibrosis by fibroscan in egyptian chronic hemodialysis patients with chronic Hepatitis C (genotype 4): A single-center study.
Abstract Assessing hepatic fibrosis in hemodialysis patients with chronic hepatitis C (CHC) can help to evaluate the long-term prognosis, complications of hepatitis C virus (HCV) as well as eligibility for renal transplantation,. Our aim was to assess liver fibrosis in Egyptian hemodialysis (HD) patients infected with CHC genotype 4 using a fibroscan. This cross-sectional observational study was conducted over two years on a cohort of 134 Egyptian patients on prevalent HD at Kasr Al Ainy Hospital. All patients were subjected to routine laboratory evaluation including, hepatitis B surface antigen, hepatitis B core ...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2017 Category: Urology & Nephrology Authors: Zayed BEM, Elsharkawy A, Abdou M, Abd Al Fatah DS, El-Shabony TH Tags: Saudi J Kidney Dis Transpl Source Type: research

Early clinical manifestations and laboratory findings before and after treatment of cytomegalovirus infection in kidney transplant patients.
In this study, we retrospectively reviewed all living related and unrelated kidney transplant recipients on regular follow-up from January 2006 to June 2015, who were suspected to have CMV clinically and confirmed by DNA polymerase chain reaction (PCR). CMV PCR was detected in 102 kidney transplant recipients. The median time of detection after kidney transplant was 21 months, ranging from 15 days to 84 months. There were 58 male and 44 female patients. The induction immunosuppression in living related kidney transplants was with antithymocyte globulin or basiliximab, whereas the most common maintenance immunosuppressive r...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2017 Category: Urology & Nephrology Authors: Siddiqui WA, Al Salmi I, Jha A, Pakkyara A, Yasir M, Shaheen FAM Tags: Saudi J Kidney Dis Transpl Source Type: research

Incident elderly patients on peritoneal dialysis: Epidemiological characteristics and modality impact on survival time.
Abstract Aging of the population and the increased prevalence of diseases such as diabetes and arterial hypertension result in an increasing need of dialysis treatment. Herein we describe a cohort of elderly patients on peritoneal dialysis (PD) and assess the influence of the modality on the long-term survival. Out of a multicenter prospective cohort of 2,144 BRAZPD PD incident patients during a period from December 2004 to October 2007, 762 elderly adults, defined as patients ≥65-year-old, were eligible for the study, 413 started on automated PD (APD) and 349 on continuous ambulatory PD (CAPD). Patients were f...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2017 Category: Urology & Nephrology Authors: Franco MRG, Bastos MG, Qureshi AR, Schreider A, Bastos KA, Divino-Filho JC, Fernandes NMS Tags: Saudi J Kidney Dis Transpl Source Type: research