Association of high-sensitive C-reactive protein and dialysis adequacy with uremic pruritus.
Abstract Uremic pruritus is a difficult symptom in chronic hemodialysis (HD) patients, and its patho-physiological mechanism remains unknown. To determine the relationship between pruritus and C-reactive protein as well as dialysis adequacy among the HD patients, we studied 241 chronic HD patients in Shiraz dialysis centers, Iran. The patients were selected by convenient sampling and the data were collected using a checklist, interview and lab tests. The mean age of our patients was 53.9 ± 16.3 years and 128 (53.1%) of them were male. There were 97 (40.2%) patients who complained of pruritus. A significant ...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Malekmakan L, Malekmakan A, Sayadi M, Pakfetrat M, Sepaskhah M, Roozbeh J Tags: Saudi J Kidney Dis Transpl Source Type: research

Non-invasive method for preventing intradialytic hypotension: A pilot study.
Abstract Intradialytic hypotension (IDH) is a life-threatening condition. We evaluated the feasibility of blood volume monitoring (BVM) and blood temperature monitoring (BTM) in preventing IDH in patients prone to the same. Fourteen hemodynamically unstable end-stage renal disease patients who were prone to IDH and unable to achieve dry weight were given BVM treatment twice weekly for two weeks. Forty patients who were not on BVM treatment served as controls. Patients were anemic, had low serum albumin (3.4 ± 0.43 g/dL) and fluid overload and were edematous. Of the 40 patients in the control group, 18 patie...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Saxena A, Sharma RK, Gupta A, John MM Tags: Saudi J Kidney Dis Transpl Source Type: research

Is CAPD a viable option among ADPKD with end stage renal disease population in India? Its outcomes and economics.
Abstract Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited renal disease, with 50-75% of these patients requiring renal replacement therapy (RRT). The outcome of peritoneal dialysis (PD) in ADPKD with end-disease renal disease (ESRD) is not clearly defined, more so in developing countries. We conducted a retrospective analysis of the outcomes and economics of PD in these ESRD patients and compared them with other causes of ESRD on PD. Data were reviewed of all the PD patients who were followed-up at our institute from January 2007 to December 2011. The inclusion criteria were ADPKD ...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Kaul A, Dharshan R, Bhadhuaria D, Prasad N, Gupta A, Sharma RK Tags: Saudi J Kidney Dis Transpl Source Type: research

Effect of progressive resistive exercise training in improving mobility and functional ability of middle adulthood patients with chronic kidney disease.
Abstract Patients with chronic kidney disease (CKD) in their middle adulthood are more prone to reduced mobility than younger patients having the same medical condition. Progressive resistive exercise training (PRT) is deemed an effective treatment approach for the management of muscular weakness in patients with CKD. The present review is an attempt to understand the effectiveness of PRT in the mobility and functional ability of patients suffering from CKD. We systematically searched electronic databases, including Medline, Scopus, PubMed, CINAHL, PEDRo and Cochrane, to review the published literature on this sub...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Sah SK, Siddiqui MA, Darain H Tags: Saudi J Kidney Dis Transpl Source Type: research

Prevalence of peripheral arterial disease diagnosed by ankle brachial index among chronic kidney disease patients in a tertiary care unit.
The objective of this study is to determine the prevalence of peripheral vascular disease (PVD) in patients with chronic kidney disease (CKD). Seventy-two patients with CKD stage 3 or above were included in this study. Blood samples were taken from each patient to determine complete blood counts, serum albumin, electrolytes, lipid profile and blood sugar random/fasting. The glomerular filtration rate (GFR) was estimated with the Cockcroft-Gault formula. The ankle-brachial index (ABI) was determined to identify the presence of PVD. A standardized Doppler ultrasound device was used. ABI of
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Laghari S, Ullah K, Masroor I, Butt G, Kifayat F Tags: Saudi J Kidney Dis Transpl Source Type: research

Metabolic syndrome and chronic kidney disease.
Abstract To determine the prevalence of metabolic syndrome (MS) in chronic kidney disease (CKD) patients as well as its effects on the progression of CKD, we conducted a prospective, longitudinal study including 180 patients with chronic renal failure followed at the outpatient service of Nephrology at the Saloul's University Hospital of Sousse (Tunisia) over six months. Our study population consisted of 101 men and 79 women. Chronic glomerulonephritis (36.6%) was the most frequent nephropathy. The mean serum creatinine was 249 ± 200 mmol/L and the mean estimated glomerular filtration rate (eGFR) was 55.8 &...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Belarbia A, Nouira S, Sahtout W, Guedri Y, Achour A Tags: Saudi J Kidney Dis Transpl Source Type: research

Microalbuminuria - A better marker in hypertensive disorders of pregnancy.
Abstract To assess the role of microalbuminuria in pre-eclampsia (PE) as a diagnostic marker, we studied 40 PE cases and 40 normotensive controls at 24 ± 4 weeks of gestation in women 20-35 years of age. The patients with PE had significant microalbuminuria in comparison with the controls, in addition to deranged renal function tests. The receiver operating characteristic curve showed that microalbuminuria had the highest sensitivity (100%) and good specificity (77.6%). Microalbuminuria had the highest area under the curve (0.869) for both diagnosis of PE and renal function assessment. Microalbuminuria also...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Babu RP, Christy A, Hegde A, Manjrekar P, Joseph M Tags: Saudi J Kidney Dis Transpl Source Type: research

Renal inflammatory response to urinary tract infection in rat neonates.
Abstract Urinary tract infection (UTI) is one of the most common bacterial infections. Maternal UTI is a risk factor for neonatal UTI. The aim of the present study was to determine the severity of renal inflammation in neonate rats born from mothers with induced UTI. Twelve pregnant rats (Sprague-Dawley) were included in study. The rats were divided into two groups (six rats in each group). In the first group, pyelonephritis was induced in the third trimester of pregnancy and the second group was used as a control group. After delivery, the neonates were divided into three groups based on days after birth (the 1 s...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Zarepour M, Moradpoor H, Emamghorashi F, Owji SM, Roodaki M, Khamoushi M Tags: Saudi J Kidney Dis Transpl Source Type: research

Long-term efficacy of atorvastatin in allograft rejection following renal transplantation: A randomized clinical trial.
In this study, patients with end-stage renal disease and candidates for kidney transplantation were divided into two groups. Group A (intervention group) received atorvastatin for two weeks prior to their transplant surgery while group B (control group) received placebo. The lipid profile was tested (triglycerides, cholesterol, LDL) in all patients two weeks before the transplantation. After transplantation, drug use was stopped. We also checked the LDL serum levels in patients with raised lipid levels (LDL>100) every two weeks. After this period, the serum lipid levels were checked monthly up to six months. Hyperlipide...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Amirzargar MA, Hosseini AT, Gholiaf M, Dadras F, Khoshjoo F Tags: Saudi J Kidney Dis Transpl Source Type: research

Bedside diagnosis of lymphorrhea after kidney transplantation surgery: A clinical study.
Abstract The aim of our study is to evaluate the role of pyridium (phenazopyridine) in the early bedside differential diagnosis of urine leak and lymphorrhea. Twenty-five kidney recipients (15 males and ten females, aged between 14 and 62 years) with persisting post-operative fluid drainage from the drain for more than two weeks were enrolled in this study. Creatinine and urea of three samples, namely serum, urine and the drain fluid, were measured. A single dose of 300 mg of pyridium (phenazopyridine) was then administered to all patients. One physician and one nurse who were unaware of the aim of the study check...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Zommorrodi A, Hajebrahimi S, Zommorrodi S Tags: Saudi J Kidney Dis Transpl Source Type: research

Hemodialysis versus peritoneal dialysis, which is cost-effective?
In this study, we aimed to compare the financial aspects of HD with PD. A total of 53 patients on HD and 43 patients on PD were included in the study and were assessed for several financial aspects of dialysis. The data collected were analyzed using SPSS-18. A statistically significant difference was noted between the HD and PD groups in the need for diagnostic tests, drugs, hospitalization, etc, with PD being less expensive. We strongly suggest physicians in our area to use PD on a larger number of patients for better financial outcome. PMID: 26354569 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Atapour A, Eshaghian A, Taheri D, Dolatkhah S Tags: Saudi J Kidney Dis Transpl Source Type: research

An unusual case of a patient who lost his native kidneys and renal allograft from cholesterol crystal emboli.
Abstract Cholesterol crystal emboli (CCE) syndrome involving native kidneys is an underdiagnosed condition. CCE is rare in renal allografts. It may present with acute kidney injury, but usually not acute graft loss. CCE should be considered in patients with a history of atherosclerosis and an invasive arterial procedure who present with acute or chronic renal allograft dysfunction. Therapy for CCE is mainly supportive and carries a high rate of mortality. To the best of our knowledge, this is the first reported case of a patient who lost his native kidneys and renal allograft due to CCE arising from his own vascul...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Ahmed W, Al Garni A, Abdelgadir E, Khamees KO, Ellouly MA, Haleem A Tags: Saudi J Kidney Dis Transpl Source Type: research

A case of primary renal allograft dysfunction due to myeloma cast nephropathy.
We report a rare case of primary renal allograft dysfunction due to myeloma cast nephropathy in a patient with no overt clinical features of multiple myeloma preceding his transplantation. A 45-year-old man on hemodialysis for six months for end-stage kidney disease due to presumed chronic glomerulonephritis developed immediate graft dysfunction post-transplantation. The graft biopsy was diagnostic of myeloma cast nephropathy. Other criteria for lambda light chain multiple myeloma were fulfilled with immunofixation electrophoresis and bone marrow biopsy. He was treated with plasmapheresis, bortezomib and high-dose dexameth...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Lingaraj U, Vankalakunti M, Radhakrishnan H, Sreedhara CG, Rajanna S Tags: Saudi J Kidney Dis Transpl Source Type: research

Prolonged hypophosphatemia following parathyroidectomy in chronic hemodialysis patients.
We present three hemodialysis patients with persistant hypophosphatemia after PTX. In our parathyroidectomized patients, hypocalcemia could be corrected with calcium and vitamin D treatment, but hypophosphatemia continued for eight months in one patient and in two other patients until the last visit (10 and 2 months, respectively). Predisposing factors such as old age, diabetes mellitus and parathyroid adenoma were not found in our patients. All three patients were younger (
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Altun E, Paydas S, Kaya B, Balal M Tags: Saudi J Kidney Dis Transpl Source Type: research

Acute kidney injury: A rare cause.
We present a young lady who consumed hair dye, which contained paraphenylene diamine (PPD), as a means of deliberate self-harm. This resulted in severe angio-neurotic edema for which she had to be ventilated, and thereafter developed rhabdomyolysis leading to acute kidney injury (AKI). The unusual aspect was that the patient continued to have flaccid quadriparesis and inability to regain kidney function. Renal biopsy performed 10 weeks after the dye consumption revealed severe acute tubular necrosis with myoglobin pigment casts. This suggests that PPD has a long-term effect leading to ongoing myoglobinuria, causing flaccid...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Mendonca S, Barki S, Mishra M, Kumar RS, Gupta D, Gupta P Tags: Saudi J Kidney Dis Transpl Source Type: research

A rare case of type-I auto-immune hepatitis and thyroiditis presenting with crescentic glomerulonephritis.
Abstract A middle-aged female patient with a past history of non-alcoholic liver disease and hypothyroidism presented with swelling of the body, off and on, for six months and rapidly worsening renal function. Renal biopsy showed crescentic glomerulonephritis with negative immunofluorescence. Serological tests were positive for anti-thyroglobulin, anti-nuclear antibody (1:80), p-anti-neutrophil cytoplasmic antibodies; gamma globulin was 5.23 g/dL and viral markers were negative. The patient was diagnosed to have autoimmune hepatitis type-1 and treated with injection methylprednisolone pulse (500 mg/day for 3 days)...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Sunder S, Venkataramanan K, Verma H, Bhardwaj M Tags: Saudi J Kidney Dis Transpl Source Type: research

Schimke immune-osseous dysplasia: A case report.
This article reports a case from Egypt with a mild form of SIOD. A 14.5-year-old male patient presented with disproportionate short stature, SRNS (focal and segmental glomerulosclerosis), laboratory evidence of cellular immune deficiency and radiologic characteristics of SED. He died at the age of 16.5 years with bone marrow failure and severe pneumonia. To the best of our knowledge, this is the first case of SIOD to be reported from Egypt. PMID: 26354575 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Bakr A, Eid R, Sarhan A, Hammad A, El-Refaey AM, El-Mougy A, Zedan MM, ElHusseini F Tags: Saudi J Kidney Dis Transpl Source Type: research

Colchicine therapy in amyloidosis related with plasmacytic castleman disease presenting with nephrotic syndrome.
Abstract Castleman disease (CD) is a neoplasm that presents with single or multiple lymphadenopathy. The disease is characterized by fever, weight loss, anemia, polyclonal hyperglobulinemia, splenomegaly, thrombocytosis and peripheral lymphadenopathy. In this paper, we report a young man with plasmacytic type CD and amyloid A (AA) deposition who presented with intra-abdominal mass and nephrotic syndrome. He was successfully treated with colchicine following surgery. PMID: 26354576 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Paydas S, Paydas S, Ergin M Tags: Saudi J Kidney Dis Transpl Source Type: research

Primary synovial sarcoma of the kidney.
Abstract Primary synovial sarcoma (SS) of the kidney is a very rare disease as well as a diagnostic dilemma. Here, we present a case of a 60-year-old male clinically diagnosed as renal cell carcinoma. The radical nephrectomy specimen showed a well-circumscribed renal mass of approximately 13 cm × 9 cm × 7 cm. The cut-surface of the mass was tawny and firm, with cystic areas, and also showed focal hemorrhage and necrosis. Histologically, the tumor was composed of spindle cells arranged in the intersecting fascicles, alternating with hypocellular areas suggestive of monophasic synovial sarcoma. Morpholog...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Mishra S, Awasthi N, Hazra SP, Bera MK Tags: Saudi J Kidney Dis Transpl Source Type: research

Candida-associated pseudo-aneurysm of the transplant renal artery presenting as malignant hypertension and managed successfully without nephrectomy.
PMID: 26354578 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Madhav D, Kumar P, Mohan C, Vijay, Mahesh U, Anusha, Suneetha, Suryaprakash Tags: Saudi J Kidney Dis Transpl Source Type: research

Novel H1N1 influenza infection among post-renal transplantation subjects: A mini review.
PMID: 26354579 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Joob B, Wiwanitkit V Tags: Saudi J Kidney Dis Transpl Source Type: research

Renal artery anastomosis to internal or external iliac artery in kidney transplant patients.
PMID: 26354580 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Daowd R, Al Ahmad A Tags: Saudi J Kidney Dis Transpl Source Type: research

Recurrent ascites secondary to endometriosis in a dialysis patient.
PMID: 26354581 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Saad AS, Chong CL, Ping LY, Tan J, Chong VH Tags: Saudi J Kidney Dis Transpl Source Type: research

Backache in patients on maintenance hemodialysis: Beware of spinal tuberculosis.
PMID: 26354582 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Yadla M, Sriramnaveen P, Kishore CK, Sivakumar V, Reddy YS, Sridhar AV, Vijayalakshmi B, Lakshmi AY Tags: Saudi J Kidney Dis Transpl Source Type: research

Comment to case report encapsulating peritoneal sclerosis (EPS): Presentation without preceding symptoms.
PMID: 26354583 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Cavoli GL, Tralongo A, Schillaci O, Ferrantellii A, Li Cavoli TV, Tralongo P, Ferrantelli G, Rotolo U Tags: Saudi J Kidney Dis Transpl Source Type: research

Acute interstitial nephritis overlapping chronic renal damage.
PMID: 26354584 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Li Cavoli G, Passantino D, Tortorici C, Bono L, Ferrantelli A, Rotolo U Tags: Saudi J Kidney Dis Transpl Source Type: research

Endovascular repair of iatrogenic subclavian artery pseudo-aneurysm.
PMID: 26354585 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Mammen S, Koshy GC, Khurana A, David V Tags: Saudi J Kidney Dis Transpl Source Type: research

Oxalate nephropathy after Jejuno-Ileal bypass surgery.
PMID: 26354586 [PubMed - in process] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Taheri D, Sarmadi T, Shahidi S, Taheri S, Mortazavi M, Atapour A, Dolatkhah S, Moayednia R Tags: Saudi J Kidney Dis Transpl Source Type: research

Epidemiology and referral patterns of patients with chronic kidney disease in the Emirate of Abu Dhabi.
This study considered all serum creatinine measurements performed between 1 September 2011 and 31 October 2012 from outpatient departments or emergency rooms. The estimated glomerular filtration rate (eGRF) was calculated using the Modification of Diet in Renal Disease formula (the Schwartz formula was used for children). We identified 331,360 samples from 212,314 individuals. The mean serum creatinine was 61 ± 48 μmol/L in females (59 ± 43 μmol/L in Emiratis, 63 ± 54 μmol/L in expatriates) and 87 ± 69 μmol/L in males (80 ± 59 μmol/L in Emiratis, 92 ± 74 μmol/L in...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Richards N, Hassan M, Saleh AK, Dastoor H, Bernieh B, Abouchacra S, Al Jabri O, Fleischmann A, Richards M, Marcelli D Tags: Saudi J Kidney Dis Transpl Source Type: research

Diabetic kidney disease and vascular comorbidities in patients with type 2 diabetes mellitus in a developing country.
Abstract Type 2 diabetes mellitus (T2DM) is associated with an increased risk of progression toward end-stage renal disease and cardiovascular (CV) risk mortality. To investigate this association, we studied 637 patients with T2DM in the Eastern area of Morocco. The mean follow-up period was 42 ± 11 months. At the baseline visit, 22.8%, 59.1% and 18.1% of the patients had normo-albuminuria, micro-albuminuria and macro-albuminuria, respectively. Of all patients, 51.6% had a history of hypertension and 37.4% had hypertension on admission. At the end of follow-up, rapid progression (estimated glomerular filtra...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Bentata Y, Chemlal A, Karimi I, El Alaoui F, Haddiya I, Abouqal R Tags: Saudi J Kidney Dis Transpl Source Type: research

Kidney biopsy in the military hospital of morocco: Complications and histopathological findings.
Abstract Epidemiological studies on renal biopsies are necessary to establish the pattern and trends of renal diseases in a particular geographic area. In this retrospective study, we reviewed the medical records, histopathology findings and complications of renal biopsy in a region of Morocco. We studied a total of 130 native kidney biopsies taken between January 2008 and January 2012. All biopsies were examined by light microscopy and immunofluorescence microscopy. There were 86 males (66.2%) and 44 females (33.8%), with a mean patient age of 44.82 ± 17.86 (range 8-86) years. The most common indications o...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Zajjari Y, Aatif T, Bahadi A, Hassani K, El Kabbaj D, Benyahia M Tags: Saudi J Kidney Dis Transpl Source Type: research

A cross-sectional study of dialysis practice-patterns in patients with chronic kidney disease on maintenance hemodialysis.
Abstract We studied the dialysis practice-patterns with regard to various aspects of chronic kidney disease (CKD) stage 5D, like anemia, mineral bone disease, vaccination, hospitalization, hypertension and cost of therapy. Four hundred and sixty-four adult hemodialysis (HD) patients from various dialysis centers of Mumbai were included in the study. The mean age of the study patients was 47.2 years. Temporary dialysis catheters were the most common initial vascular access. Thirteen percent of prevalent HD patients were on temporary catheters; 33% of patients had history of failure of arterio-venous fistula. The mo...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Kulkarni MJ, Jamale T, Hase NK, Jagdish PK, Keskar V, Patil H, Shete A, Patil C Tags: Saudi J Kidney Dis Transpl Source Type: research

Spectrum of IgA nephropathy in a single center.
Abstract Immunoglobulin A (IgA) nephropathy (IgAN) is the most common biopsy-proven primary glomerular disease in the world and a major contributor to the worldwide burden of endstage renal failure, with a wide geographical variation. To determine the incidence, clinical profile and histological pattern of IgAN in our institute, we reviewed all the patients who had native kidney biopsies with the diagnosis of primary IgAN during the period from 1998 to 2009 in the context of the clinical features. A total of 116 patients with IgAN were finally analyzed; 85 (73%) of the patients were male, the mean age of the patie...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: Das U, Dakshinamurty KV, Prayaga A, Uppin M Tags: Saudi J Kidney Dis Transpl Source Type: research

Acute glomerulonephritis in children of the Niger Delta region of Nigeria.
Abstract A three-year retrospective study was conducted to determine the incidence, pattern of presentation and other clinical and biochemical features as well as outcome of treatment of patients admitted with acute glomerulonephritis at the Delta State University Teaching Hospital, Oghara and GN Children's Clinic, Warri. The case notes of all the children who presented with renal diseases from January 2010 to December 2012 were retrieved and those with acute glomerulonephritis were analyzed. A total of 20 patients (13 male and seven female) with acute glomerulonephritis were seen during the three-year period unde...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2015 Category: Urology & Nephrology Authors: McGil Ugwu GI Tags: Saudi J Kidney Dis Transpl Source Type: research

Sequential changes in bone biochemical parameters and bone mineral density after renal transplant.
Abstract To evaluate sequential changes in biochemical bone parameters, parathyroid hormone (iPTH), vitamin D levels and bone mineral density (BMD) over a period of 24 weeks after renal transplantation, we studied 75 patients (58 males, with a mean age of 35.4 years) who underwent their first renal transplantation without a past history of parathyroid surgery or fractures. Serum calcium, phosphorus and albumin were measured before transplant, then weekly for four weeks and monthly for the following 20 weeks. Serum iPTH and vitamin D levels and BMD were measured at baseline and 24 weeks after transplantation. After...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: Rathi M, Kumar D, Bhadada SK, Khandelwal N, Kohli HS, Jha V, Sakhuja V Tags: Saudi J Kidney Dis Transpl Source Type: research

Prevalence of oral lesions in kidney transplant patients: A single center experience.
Abstract Kidney transplant patients (KTPs) have a potential tendency to develop oral lesions due to the administration of immunosuppressive drugs, but their prevalence is still obscure. The aim of the present study was to investigate the oral clinical findings in a group of renal transplant patients in comparison with ageand sex-matched healthy controls (HCs). Three hundred KTPs who underwent transplantation at least six months earlier and 296 HCs were examined clinically for the presence of any oral lesions. Demographic and additional details regarding medications, systemic diseases and duration after transplanta...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: Kaswan S, Patil S, Maheshwari S, Wadhawan R Tags: Saudi J Kidney Dis Transpl Source Type: research

Robotic-assisted versus laparoscopic partial nephrectomy: An experience with a novel technique of suturing.
This study was conducted to evaluate whether robotic-assisted laparoscopic partial nephrectomy (RALPN) is superior to laparoscopic partial nephrectomy (LPN) with regard to warm ischemia time and complications and, in addition, to report our novel technique of suturing in partial nephrectomy (PN). This was a prospective study carried out over a period of six years at our institute. A single surgeon performed PNs laparoscopically (17) and with robotic assistance (16). Only exophytic tumors were included and a novel technique of knotless and bolster-less suturing using Hem-o-loc clips was used to close the renal defect. There...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: Dar TI, Tyagi V, Sharma A, Kathuria S, Chadha S, Khawaja AR Tags: Saudi J Kidney Dis Transpl Source Type: research

Comparison of C-reactive protein levels with delivered dose of Kt/V in patients with end-stage renal disease on maintenance hemodialysis.
The objective of our study is to compare the C-reactive protein (CRP) levels with the delivered dose of dialysis in terms of Kt/V in patients undergoing maintenance hemodialysis (HD). This is a comparative, cross-sectional survey. The study was conducted at the HD unit of the Shaikh Zayed Hospital, Lahore, Pakistan. Patients who fulfilled the inclusion and exclusion criteria were enrolled in this study. The delivered dose of HD (Kt/V) was assessed by an online clearance module (OCM) in Fresenius machines at the end of every dialysis session and the weekly Kt/V was determined by adding all three Kt/V values. The serum CRP s...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: Rashid H, Rizwan-ul-CollectiveNameHaq, Abad-ur-Rehman Tags: Saudi J Kidney Dis Transpl Source Type: research

Nutritional assessment and its correlation with anthropometric measurements in hemodialysis patients.
This study is aimed to assess the prevalence of malnutrition using a subjective global assessment (SGA) in HD patients referred to the Valie ASR Hospital, Arak, Iran. In this descriptive analysis study, 190 HD patients were selected with random sampling. SGA and anthropometric and biochemical measurements were assessed in all patients. Data were analyzed with the Chi-square and t-tests and Pearson correlation coefficient. P 50% of patients on maintenance HD had mild or moderate malnutrition. There was no case of severe malnutrition. Duration of dialysis treatment and some anthropometric indices (weight, BMI and MAC) also s...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: Koor BE, Nakhaie MR, Babaie S Tags: Saudi J Kidney Dis Transpl Source Type: research

Improvement in glomerular filtration rate may decrease mortality among type-2 diabetics with chronic kidney disease lacking proteinuria: A retrospective study.
Abstract Twenty percent of patients with type-2 diabetes mellitus without albuminuria progress to chronic kidney disease (CKD). The various factors related to development of CKD, the natural course of renal dysfunction as well as mortality in this sub-group of diabetics has not been studied in detail. The medical records of 121 patients (all males) above the age of 40 years with type-2 diabetes mellitus and CKD, and without proteinuria, were reviewed in this retrospective study. The outcomes measured included: (a) all-cause mortality, (b) need for hemodialysis (HD), (c) appearance of proteinuria and (d) trend in k...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: Thajudeen B, Budhiraja P, Meister E, Popovtzer M Tags: Saudi J Kidney Dis Transpl Source Type: research

Spectrum of clinico-pathological profile and treatment response in children with nephrotic immunoglobulin a nephropathy.
Abstract Immunoglobulin A nephropathy (IgAN) is one of the most common types of primary glomerulonephritis in the world. Nephrotic syndrome is an uncommon presentation of IgAN. To evaluate the clinico-pathological features and treatment response of nephrotic IgAN, we prospectively studied 20 nephrotic children with biopsy-proven IgAN at our center from August 2009 to December 2012. The histopathological characterization of IgAN was carried out with the HAAS classification. The demographic profile, clinical presentation, initial laboratory, biopsy findings and treatment response were analyzed. The mean age was 6.7 ...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: Pradhan SK, Sivaraj P, Das L, Swain A Tags: Saudi J Kidney Dis Transpl Source Type: research

Serum cystatin-C and BETA 2-microglobulin as accurate markers in the early diagnosis of kidney injury in neonates: A single center study.
Abstract Early detection of kidney injury in neonates is very important for appropriate management and prevention of serious complications; however, commonly used detectors as creatinine and blood urea nitrogen (BUN) do not directly reflect early renal cell injury. Serum cystatin-C (Cys-C) and beta 2-microglobulin (Β2M), serum creatinine and BUN were assessed in 20 neonates who developed renal impairment after admission to the neonatal intensive care unit and 10 healthy neonates. The means of serum Cys-C, Β2M and creatinine on Day 1 of admission in the cases and control groups were 2.15 ± 0.52 vs ...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: El-Frargy MS, El-Refaey AM, Eid R, Hussien MA Tags: Saudi J Kidney Dis Transpl Source Type: research

Cystatin C is an early marker of contrast-induced nephropathy in patients with sepsis in the intensive care unit.
In conclusion, a relatively high prevalence of CIN was found in all disease groups. No demographic or disease factors were found to be associated with the development of CIN. Cystatin C may be a useful early marker of CIN in sepsis patients, but further work is required to understand the difference in cystatin C expression levels in patients with different underlying pathologies. PMID: 26178544 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: Al-Beladi FI Tags: Saudi J Kidney Dis Transpl Source Type: research

Clinical outcomes of acute kidney injury patients treated in a single-center, sub-urban satellite hospital.
Abstract Acute kidney injury (AKI) is a common diagnosis among critically ill patients. Although the etiology of AKI will determine the appropriate initial management, the definitive management of established AKI is still debatable. This is a retrospective, observational, single-center analysis of a cohort of patients referred to the nephrology unit for AKI from 1st August 2010 to 31st January 2011. Those patients with indications for dialysis were treated with continuous renal replacement therapy, intermittent hemodialysis or stiff-catheter peritoneal dialysis as determined by their hemodynamic status and the tec...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: Mohd Nor FS, Draman CR, Seman MR, Abd Manaf N, Abd Ghani AS, Hassan KA Tags: Saudi J Kidney Dis Transpl Source Type: research

Cost-effectiveness of kidney transplantation compared with chronic dialysis in end-stage renal disease.
Abstract To estimate the costs and effectiveness measured in quality-adjusted life years (QALY) of kidney transplantation compared with dialysis in adults suffering from end-stage renal disease from the perspective of the Colombian healthcare system, we designed a Markov model with monthly cycles over a five-year time horizon and eight transitional states, including death as an absorbing state. Transition probabilities were obtained from international registries, costs from different local sources [case studies, official tariffs (ISS 2001 + 35%) for procedures and SISMED for medications]. Data were validated by an...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: Rosselli D, Rueda JD, Diaz CE Tags: Saudi J Kidney Dis Transpl Source Type: research

Hemodiafiltration using pre-dilutional on-line citrate dialysate: A new technique for regional citrate anticoagulation: A feasibility study.
Abstract A prospective, observational, feasibility study was carried out on four patients with end-stage renal failure undergoing bicarbonate hemodialysis to study the feasibility of an on-line hemodiafiltration technique using a citrate dialysate with pre-dilutional infusion of citrate as a technique for regional citrate anticoagulation. All patients had contraindication to systemic heparin anticoagulation. The dialysis technique consisted of an on-line hemodiafiltration with a citrate dialysate without calcium using a Fresenius 4008S dialysis machine and Fresenius Polysulfone F60 dialyzers. The infusion solution...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: Bousselmi R, Baffoun A, Hajjej Z, Saleh MB, Labbene I, Ferjani M, Hmida MJ Tags: Saudi J Kidney Dis Transpl Source Type: research

Effective ultrafiltration with acute peritoneal dialysis in a child with diuretic-resistant nephrotic edema.
We report a child with steroid-resistant nephrotic syndrome with diuretic-resistant nephrotic edema treated successfully using acute peritoneal dialysis as a means of UF. PMID: 26178548 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: Barman H, Sirie R, Duwarah SG Tags: Saudi J Kidney Dis Transpl Source Type: research

Retained fragmented double J ureteric stent: A report of four cases with review of the literature.
Abstract Polyurethane double-J ureteral stents are widely used in the field of urology. Postoperatively, patient education about the ureteral stent and making sure it is removed at the prescribed time is an utmost necessity. Forgotten ureteral stent is not only disastrous for the patient but also fraught with serious medico-legal implications for the urologist. Herein, we present four cases of long-term retained part of ureteral stent with its varied presentation and subsequent management. PMID: 26178549 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: Goel HK, Kundu AK, Maji TK, Pal DK Tags: Saudi J Kidney Dis Transpl Source Type: research

Kidney involvement in Crow-Fukase syndrome.
sa FB Abstract Crow-Fukase syndrome, also known as POEMS syndrome, is a rare plasma dyscrasia characterized by monoclonal gammopathy and various combinations of polyneuropathy, organomegaly, endocrinopathy and dermatological changes, and their initials stand for the acronym POEMS. Substantial kidney involvement is rarely related to this disease. Our report is about five patients suffering from the POEMS syndrome with kidney involvement that rapidly progressed to end-stage renal disease. Our report is about three females and two males with a mean age of 60.6 years. Neuropathy was noted in all the cases. Endocrinopa...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: Zouaghi K, Fatma LB, Hajri S, Khedher R, Krid M, Smaoui W, Béji S, Rais L, Moussa FB Tags: Saudi J Kidney Dis Transpl Source Type: research

Sodium stibogluconate-associated acute interstitial nephritis in a patient treated for visceral leishmaniasis.
We describe a 32-year-old male patient who was treated for visceral leishmaniasis with sodium stibogluconate. The patient was readmitted two weeks after completion of the treatment for evaluation of AKI. Kidney biopsy revealed marked acute interstitial nephritis. The renal dysfunction reversed totally after a course of corticosteroids. Antimonials should be recognized as a new class of agents as a possible cause of drug-induced acute interstitial nephritis. PMID: 26178551 [PubMed - as supplied by publisher] (Source: Saudi Journal of Kidney Diseases and Transplantation)
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2015 Category: Urology & Nephrology Authors: Vikrant S, Gupta D, Kaushal SS Tags: Saudi J Kidney Dis Transpl Source Type: research