The reconstitution of T-cells after Allogeneic Hematopoietic Stem Cell Transplant in a Pediatric Patient with Congenital Amegakaryocytic Thrombocytopenia (CAMT)
CONCLUSION: Successful treatment of acute GvHD prevented advancing the condition to chronic GvHD, and this was accompanied by delayed T-cell reconstitution through an increase in Treg:Tcons ratio.PMID:37526450 | DOI:10.2174/1871530323666230801100113 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 1, 2023 Category: Endocrinology Authors: Shideh Namazi Bayegi Amir Ali Hamidieh Maryam Behfar Amene Saghazadeh Mahmood Bozorgmehr Nader Tajik Ali Akbar Delbandi Samaneh Delavari Mehdi Shekarabi Nima Rezaei Source Type: research
The reconstitution of T-cells after Allogeneic Hematopoietic Stem Cell Transplant in a Pediatric Patient with Congenital Amegakaryocytic Thrombocytopenia (CAMT)
CONCLUSION: Successful treatment of acute GvHD prevented advancing the condition to chronic GvHD, and this was accompanied by delayed T-cell reconstitution through an increase in Treg:Tcons ratio.PMID:37526450 | DOI:10.2174/1871530323666230801100113 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 1, 2023 Category: Drugs & Pharmacology Authors: Shideh Namazi Bayegi Amir Ali Hamidieh Maryam Behfar Amene Saghazadeh Mahmood Bozorgmehr Nader Tajik Ali Akbar Delbandi Samaneh Delavari Mehdi Shekarabi Nima Rezaei Source Type: research
The reconstitution of T-cells after Allogeneic Hematopoietic Stem Cell Transplant in a Pediatric Patient with Congenital Amegakaryocytic Thrombocytopenia (CAMT)
CONCLUSION: Successful treatment of acute GvHD prevented advancing the condition to chronic GvHD, and this was accompanied by delayed T-cell reconstitution through an increase in Treg:Tcons ratio.PMID:37526450 | DOI:10.2174/1871530323666230801100113 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 1, 2023 Category: Endocrinology Authors: Shideh Namazi Bayegi Amir Ali Hamidieh Maryam Behfar Amene Saghazadeh Mahmood Bozorgmehr Nader Tajik Ali Akbar Delbandi Samaneh Delavari Mehdi Shekarabi Nima Rezaei Source Type: research
Generalized Vitiligo After Stem Cell Transplantation: A Case Report
Clin Cosmet Investig Dermatol. 2023 Jul 25;16:1945-1948. doi: 10.2147/CCID.S420342. eCollection 2023.ABSTRACTGraft versus host disease (GVHD) is a complex immune-mediated pathophysiological process, which is caused by allogenic immune reactions between donors and recipients. No matter ac-ute or chronic GVHD, skin involvement is the most common, severe skin damage can lead to permanent disfigurement, which seriously affects the long-term quality of life of patients. We herein report a patient with generalized vitiligo after allogeneic peripheral hematopoietic stem cell transplantation (allo-HSCT) for aplastic anemia.PMID:37...
Source: Clinical, Cosmetic and Investigational Dermatology - July 31, 2023 Category: Dermatology Authors: Yunxia Wang Wenting Hu Fuquan Lin Ai E Xu Source Type: research
Busulfan for allogeneic hematopoietic stem cell transplantation in children with severe aplastic anemia: A retrospective study
Discussion In children with SAA undergoing allo-HSCT, conditioning regimen with Bu + Flu + Cy + ATG-F is capable of enhancing the myeloablation effect, promoting donor hematopoietic stem cell engraftment, and reducing the graft failure rate. Furthermore, it does not increase the incidence of complications, including GVHD.PMID:37524052 | DOI:10.1159/000531687 (Source: Acta Haematologica)
Source: Acta Haematologica - July 31, 2023 Category: Hematology Authors: Yingjian Si Rongmu Luo Maoquan Qin Zhenlan Du Xiaomei Zhang Ya Wang Wei Chen Wenjing Gu Guosheng Xing Lingsong Dou Wei Cao Zhichun Feng Source Type: research
Generalized Vitiligo After Stem Cell Transplantation: A Case Report
Clin Cosmet Investig Dermatol. 2023 Jul 25;16:1945-1948. doi: 10.2147/CCID.S420342. eCollection 2023.ABSTRACTGraft versus host disease (GVHD) is a complex immune-mediated pathophysiological process, which is caused by allogenic immune reactions between donors and recipients. No matter ac-ute or chronic GVHD, skin involvement is the most common, severe skin damage can lead to permanent disfigurement, which seriously affects the long-term quality of life of patients. We herein report a patient with generalized vitiligo after allogeneic peripheral hematopoietic stem cell transplantation (allo-HSCT) for aplastic anemia.PMID:37...
Source: Clinical, Cosmetic and Investigational Dermatology - July 31, 2023 Category: Dermatology Authors: Yunxia Wang Wenting Hu Fuquan Lin Ai E Xu Source Type: research
Busulfan for allogeneic hematopoietic stem cell transplantation in children with severe aplastic anemia: A retrospective study
Discussion In children with SAA undergoing allo-HSCT, conditioning regimen with Bu + Flu + Cy + ATG-F is capable of enhancing the myeloablation effect, promoting donor hematopoietic stem cell engraftment, and reducing the graft failure rate. Furthermore, it does not increase the incidence of complications, including GVHD.PMID:37524052 | DOI:10.1159/000531687 (Source: Acta Haematologica)
Source: Acta Haematologica - July 31, 2023 Category: Hematology Authors: Yingjian Si Rongmu Luo Maoquan Qin Zhenlan Du Xiaomei Zhang Ya Wang Wei Chen Wenjing Gu Guosheng Xing Lingsong Dou Wei Cao Zhichun Feng Source Type: research
Busulfan for allogeneic hematopoietic stem cell transplantation in children with severe aplastic anemia: A retrospective study
Discussion In children with SAA undergoing allo-HSCT, conditioning regimen with Bu + Flu + Cy + ATG-F is capable of enhancing the myeloablation effect, promoting donor hematopoietic stem cell engraftment, and reducing the graft failure rate. Furthermore, it does not increase the incidence of complications, including GVHD.PMID:37524052 | DOI:10.1159/000531687 (Source: Acta Haematologica)
Source: Acta Haematologica - July 31, 2023 Category: Hematology Authors: Yingjian Si Rongmu Luo Maoquan Qin Zhenlan Du Xiaomei Zhang Ya Wang Wei Chen Wenjing Gu Guosheng Xing Lingsong Dou Wei Cao Zhichun Feng Source Type: research
Busulfan for allogeneic hematopoietic stem cell transplantation in children with severe aplastic anemia: A retrospective study
Discussion In children with SAA undergoing allo-HSCT, conditioning regimen with Bu + Flu + Cy + ATG-F is capable of enhancing the myeloablation effect, promoting donor hematopoietic stem cell engraftment, and reducing the graft failure rate. Furthermore, it does not increase the incidence of complications, including GVHD.PMID:37524052 | DOI:10.1159/000531687 (Source: Acta Haematologica)
Source: Acta Haematologica - July 31, 2023 Category: Hematology Authors: Yingjian Si Rongmu Luo Maoquan Qin Zhenlan Du Xiaomei Zhang Ya Wang Wei Chen Wenjing Gu Guosheng Xing Lingsong Dou Wei Cao Zhichun Feng Source Type: research
Busulfan for allogeneic hematopoietic stem cell transplantation in children with severe aplastic anemia: A retrospective study
Discussion In children with SAA undergoing allo-HSCT, conditioning regimen with Bu + Flu + Cy + ATG-F is capable of enhancing the myeloablation effect, promoting donor hematopoietic stem cell engraftment, and reducing the graft failure rate. Furthermore, it does not increase the incidence of complications, including GVHD.PMID:37524052 | DOI:10.1159/000531687 (Source: Acta Haematologica)
Source: Acta Haematologica - July 31, 2023 Category: Hematology Authors: Yingjian Si Rongmu Luo Maoquan Qin Zhenlan Du Xiaomei Zhang Ya Wang Wei Chen Wenjing Gu Guosheng Xing Lingsong Dou Wei Cao Zhichun Feng Source Type: research
Busulfan for allogeneic hematopoietic stem cell transplantation in children with severe aplastic anemia: A retrospective study
Discussion In children with SAA undergoing allo-HSCT, conditioning regimen with Bu + Flu + Cy + ATG-F is capable of enhancing the myeloablation effect, promoting donor hematopoietic stem cell engraftment, and reducing the graft failure rate. Furthermore, it does not increase the incidence of complications, including GVHD.PMID:37524052 | DOI:10.1159/000531687 (Source: Acta Haematologica)
Source: Acta Haematologica - July 31, 2023 Category: Hematology Authors: Yingjian Si Rongmu Luo Maoquan Qin Zhenlan Du Xiaomei Zhang Ya Wang Wei Chen Wenjing Gu Guosheng Xing Lingsong Dou Wei Cao Zhichun Feng Source Type: research
Comparison of haploidentical –allogeneic hematopoietic stem cell transplantation and intensive immunosuppressive therapy for patients with severe aplastic anemia with an absolute neutrophil count of zero: a retrospective study
AbstractA retrospective analysis was conducted based on the clinical data from 60 patients older than 16 years from January 2016 to January 2021. All the patients were newly diagnosed with severe aplastic anemia (SAA) with an absolute neutrophil count (ANC) of zero. We compared the hematological response and survival of haploidentical –allogeneic hematopoietic stem cell transplantation (HID-HSCT) (n = 25) and intensive immunosuppressive therapy (IST) (n = 35) treatments. At six months, the overall response rate and complete response were significantly higher in the HID-HSCT group than those in the IST group (84.0% vs. 40...
Source: Annals of Hematology - July 23, 2023 Category: Hematology Source Type: research
Elevated TCR- αβ < sup > + < /sup > double-negative T cells in pediatric patients with acquired aplastic anemia
CONCLUSION: Our observations suggest that elevated TCR-αβ+ DNTs seems to play a role in the pathogenesis of aAA, and it was involve in immune response to IST.PMID:37479012 | DOI:10.1016/j.cca.2023.117492 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - July 21, 2023 Category: Chemistry Authors: Hui Chen Xingjuan Xie Jie Ma Lingling Fu Xiaoxi Zhao Tian Yu Xing Chao Gao Runhui Wu Zhenping Chen Source Type: research
Elevated TCR- αβ < sup > + < /sup > double-negative T cells in pediatric patients with acquired aplastic anemia
CONCLUSION: Our observations suggest that elevated TCR-αβ+ DNTs seems to play a role in the pathogenesis of aAA, and it was involve in immune response to IST.PMID:37479012 | DOI:10.1016/j.cca.2023.117492 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - July 21, 2023 Category: Chemistry Authors: Hui Chen Xingjuan Xie Jie Ma Lingling Fu Xiaoxi Zhao Tian Yu Xing Chao Gao Runhui Wu Zhenping Chen Source Type: research
The Use of an Iterative Strategy of Cognitive Interview and Expert Consultation to Revise the Quality of Life Scale for Patients with Aplastic Anemia (QLS-AA)
(Source: Patient Preference and Adherence)
Source: Patient Preference and Adherence - July 19, 2023 Category: International Medicine & Public Health Tags: Patient Preference and Adherence Source Type: research
