Reflections: A New Monthly Feature in Transplantation and Cellular Therapy
The early years of marrow transplantation were difficult. Some leaders left the field and programs closed. During those trying times over 50 years ago, it was the success of transplants for severe aplastic anemia and the demonstration that a number of patients with refractory leukemia could be cured that kept the field going. (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - July 1, 2023 Category: Hematology Authors: Keith M. Sullivan, Stephen J. Forman, Robert Korngold, David L. Porter Tags: Reflections Source Type: research
Clinical data analysis of 86 patients with invasive infections caused by Malassezia furfur from a tertiary medical center and 37 studies
ConclusionsM. furfur can cause a variety of invasive infections. These patients mostly occur in premature infants, low immunity and severe gastrointestinal diseases. Indwelling catheters and TPN infusion are major risk factors. AmB, l-AmB and azoles are the most commonly used agents, and simultaneous removal of the catheter and termination of TPN infusion are important for the treatment of M. furfur invasive infections. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - June 29, 2023 Category: Microbiology Source Type: research
Fludarabine-based low-intensity conditioning for fanconi anemia is associated with good outcomes in aplastic anemia but not in mds - a single-center experience
Conclusion: SCT using a fully matched donor provides good outcomes with low-intensity conditioning regimens in patients with FA who have an aplastic marrow. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2023 Category: Hematology Authors: Biju George, Sohini Chattopadhyay, Sharon Lionel, Sushil Selvarajan, Anup Devasia, Anu Korula, Uday Kulkarni, Fouzia Aboobacker, Eunice Sindhuvi, Kavitha Lakshmi, Alok Srivastava, Aby Abraham, Vikram Mathews Source Type: research