Secondary Pure Red Cell Aplasia During Daratumumab/ Hyaluronidase Therapy for Multiple Myeloma
Oncology (Williston Park). 2023 Oct 10;37(10):419-424. doi: 10.46883/2023.25921006.ABSTRACTPredominantly autoimmune in origin, severe normochromic, normocytic anemia with reticulocytopenia in the setting of the normal production of leukocytes and megakaryocytic lineages is known as pure red cell aplasia (PRCA), which is unlike aplastic anemia in which all lineages are affected due to a stem cell defect. PRCA can be primary (such as autoimmune) or acquired, which can be an acute self-limited illness or a chronic disease that may be induced by medications, including immunotherapy such as monoclonal antibodies (mAbs). Daratum...
Source: Oncology (Williston Park, N.Y.) - October 25, 2023 Category: Cancer & Oncology Authors: Ludovic Saba Kevin S Landau Silvia Bunting Chakra P Chaulagain Source Type: research

Porcine antilymphocyte globulin versus rabbit antithymocyte globulin for intensive immunosuppressive therapy of acquired aplastic anemia: A meta-analysis and systematic review
CONCLUSION: The efficacy of pALG in AA patients is equivalent to that of rATG. rATG was associated with a significantly higher incidence rate of infection than pALG.PMID:37877292 | DOI:10.5414/CP204379 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - October 25, 2023 Category: Drugs & Pharmacology Authors: Jinsong Jia Shasha Wang Ying Kang Xiujuan Liu Lanping Xu Source Type: research

Secondary Pure Red Cell Aplasia During Daratumumab/ Hyaluronidase Therapy for Multiple Myeloma
Oncology (Williston Park). 2023 Oct 10;37(10):419-424. doi: 10.46883/2023.25921006.ABSTRACTPredominantly autoimmune in origin, severe normochromic, normocytic anemia with reticulocytopenia in the setting of the normal production of leukocytes and megakaryocytic lineages is known as pure red cell aplasia (PRCA), which is unlike aplastic anemia in which all lineages are affected due to a stem cell defect. PRCA can be primary (such as autoimmune) or acquired, which can be an acute self-limited illness or a chronic disease that may be induced by medications, including immunotherapy such as monoclonal antibodies (mAbs). Daratum...
Source: Oncology (Williston Park, N.Y.) - October 25, 2023 Category: Cancer & Oncology Authors: Ludovic Saba Kevin S Landau Silvia Bunting Chakra P Chaulagain Source Type: research

Porcine antilymphocyte globulin versus rabbit antithymocyte globulin for intensive immunosuppressive therapy of acquired aplastic anemia: A meta-analysis and systematic review
CONCLUSION: The efficacy of pALG in AA patients is equivalent to that of rATG. rATG was associated with a significantly higher incidence rate of infection than pALG.PMID:37877292 | DOI:10.5414/CP204379 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - October 25, 2023 Category: Drugs & Pharmacology Authors: Jinsong Jia Shasha Wang Ying Kang Xiujuan Liu Lanping Xu Source Type: research

Secondary Pure Red Cell Aplasia During Daratumumab/ Hyaluronidase Therapy for Multiple Myeloma
Oncology (Williston Park). 2023 Oct 10;37(10):419-424. doi: 10.46883/2023.25921006.ABSTRACTPredominantly autoimmune in origin, severe normochromic, normocytic anemia with reticulocytopenia in the setting of the normal production of leukocytes and megakaryocytic lineages is known as pure red cell aplasia (PRCA), which is unlike aplastic anemia in which all lineages are affected due to a stem cell defect. PRCA can be primary (such as autoimmune) or acquired, which can be an acute self-limited illness or a chronic disease that may be induced by medications, including immunotherapy such as monoclonal antibodies (mAbs). Daratum...
Source: Oncology (Williston Park, N.Y.) - October 25, 2023 Category: Cancer & Oncology Authors: Ludovic Saba Kevin S Landau Silvia Bunting Chakra P Chaulagain Source Type: research

Porcine antilymphocyte globulin versus rabbit antithymocyte globulin for intensive immunosuppressive therapy of acquired aplastic anemia: A meta-analysis and systematic review
CONCLUSION: The efficacy of pALG in AA patients is equivalent to that of rATG. rATG was associated with a significantly higher incidence rate of infection than pALG.PMID:37877292 | DOI:10.5414/CP204379 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - October 25, 2023 Category: Drugs & Pharmacology Authors: Jinsong Jia Shasha Wang Ying Kang Xiujuan Liu Lanping Xu Source Type: research

Secondary Pure Red Cell Aplasia During Daratumumab/ Hyaluronidase Therapy for Multiple Myeloma
Oncology (Williston Park). 2023 Oct 10;37(10):419-424. doi: 10.46883/2023.25921006.ABSTRACTPredominantly autoimmune in origin, severe normochromic, normocytic anemia with reticulocytopenia in the setting of the normal production of leukocytes and megakaryocytic lineages is known as pure red cell aplasia (PRCA), which is unlike aplastic anemia in which all lineages are affected due to a stem cell defect. PRCA can be primary (such as autoimmune) or acquired, which can be an acute self-limited illness or a chronic disease that may be induced by medications, including immunotherapy such as monoclonal antibodies (mAbs). Daratum...
Source: Oncology (Williston Park, N.Y.) - October 25, 2023 Category: Cancer & Oncology Authors: Ludovic Saba Kevin S Landau Silvia Bunting Chakra P Chaulagain Source Type: research

Porcine antilymphocyte globulin versus rabbit antithymocyte globulin for intensive immunosuppressive therapy of acquired aplastic anemia: A meta-analysis and systematic review
CONCLUSION: The efficacy of pALG in AA patients is equivalent to that of rATG. rATG was associated with a significantly higher incidence rate of infection than pALG.PMID:37877292 | DOI:10.5414/CP204379 (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - October 25, 2023 Category: Drugs & Pharmacology Authors: Jinsong Jia Shasha Wang Ying Kang Xiujuan Liu Lanping Xu Source Type: research

Secondary Pure Red Cell Aplasia During Daratumumab/ Hyaluronidase Therapy for Multiple Myeloma
Oncology (Williston Park). 2023 Oct 10;37(10):419-424. doi: 10.46883/2023.25921006.ABSTRACTPredominantly autoimmune in origin, severe normochromic, normocytic anemia with reticulocytopenia in the setting of the normal production of leukocytes and megakaryocytic lineages is known as pure red cell aplasia (PRCA), which is unlike aplastic anemia in which all lineages are affected due to a stem cell defect. PRCA can be primary (such as autoimmune) or acquired, which can be an acute self-limited illness or a chronic disease that may be induced by medications, including immunotherapy such as monoclonal antibodies (mAbs). Daratum...
Source: Oncology (Williston Park, N.Y.) - October 25, 2023 Category: Cancer & Oncology Authors: Ludovic Saba Kevin S Landau Silvia Bunting Chakra P Chaulagain Source Type: research

Secondary Pure Red Cell Aplasia During Daratumumab/ Hyaluronidase Therapy for Multiple Myeloma
Oncology (Williston Park). 2023 Oct 10;37(10):419-424. doi: 10.46883/2023.25921006.ABSTRACTPredominantly autoimmune in origin, severe normochromic, normocytic anemia with reticulocytopenia in the setting of the normal production of leukocytes and megakaryocytic lineages is known as pure red cell aplasia (PRCA), which is unlike aplastic anemia in which all lineages are affected due to a stem cell defect. PRCA can be primary (such as autoimmune) or acquired, which can be an acute self-limited illness or a chronic disease that may be induced by medications, including immunotherapy such as monoclonal antibodies (mAbs). Daratum...
Source: Oncology (Williston Park, N.Y.) - October 25, 2023 Category: Cancer & Oncology Authors: Ludovic Saba Kevin S Landau Silvia Bunting Chakra P Chaulagain Source Type: research

Secondary Pure Red Cell Aplasia During Daratumumab/ Hyaluronidase Therapy for Multiple Myeloma
Oncology (Williston Park). 2023 Oct 10;37(10):419-424. doi: 10.46883/2023.25921006.ABSTRACTPredominantly autoimmune in origin, severe normochromic, normocytic anemia with reticulocytopenia in the setting of the normal production of leukocytes and megakaryocytic lineages is known as pure red cell aplasia (PRCA), which is unlike aplastic anemia in which all lineages are affected due to a stem cell defect. PRCA can be primary (such as autoimmune) or acquired, which can be an acute self-limited illness or a chronic disease that may be induced by medications, including immunotherapy such as monoclonal antibodies (mAbs). Daratum...
Source: Oncology (Williston Park, N.Y.) - October 25, 2023 Category: Cancer & Oncology Authors: Ludovic Saba Kevin S Landau Silvia Bunting Chakra P Chaulagain Source Type: research

Secondary Pure Red Cell Aplasia During Daratumumab/ Hyaluronidase Therapy for Multiple Myeloma
Oncology (Williston Park). 2023 Oct 10;37(10):419-424. doi: 10.46883/2023.25921006.ABSTRACTPredominantly autoimmune in origin, severe normochromic, normocytic anemia with reticulocytopenia in the setting of the normal production of leukocytes and megakaryocytic lineages is known as pure red cell aplasia (PRCA), which is unlike aplastic anemia in which all lineages are affected due to a stem cell defect. PRCA can be primary (such as autoimmune) or acquired, which can be an acute self-limited illness or a chronic disease that may be induced by medications, including immunotherapy such as monoclonal antibodies (mAbs). Daratum...
Source: Oncology (Williston Park, N.Y.) - October 25, 2023 Category: Cancer & Oncology Authors: Ludovic Saba Kevin S Landau Silvia Bunting Chakra P Chaulagain Source Type: research

Secondary Pure Red Cell Aplasia During Daratumumab/ Hyaluronidase Therapy for Multiple Myeloma
Oncology (Williston Park). 2023 Oct 10;37(10):419-424. doi: 10.46883/2023.25921006.ABSTRACTPredominantly autoimmune in origin, severe normochromic, normocytic anemia with reticulocytopenia in the setting of the normal production of leukocytes and megakaryocytic lineages is known as pure red cell aplasia (PRCA), which is unlike aplastic anemia in which all lineages are affected due to a stem cell defect. PRCA can be primary (such as autoimmune) or acquired, which can be an acute self-limited illness or a chronic disease that may be induced by medications, including immunotherapy such as monoclonal antibodies (mAbs). Daratum...
Source: Oncology (Williston Park, N.Y.) - October 25, 2023 Category: Cancer & Oncology Authors: Ludovic Saba Kevin S Landau Silvia Bunting Chakra P Chaulagain Source Type: research

Secondary Pure Red Cell Aplasia During Daratumumab/ Hyaluronidase Therapy for Multiple Myeloma
Oncology (Williston Park). 2023 Oct 10;37(10):419-424. doi: 10.46883/2023.25921006.ABSTRACTPredominantly autoimmune in origin, severe normochromic, normocytic anemia with reticulocytopenia in the setting of the normal production of leukocytes and megakaryocytic lineages is known as pure red cell aplasia (PRCA), which is unlike aplastic anemia in which all lineages are affected due to a stem cell defect. PRCA can be primary (such as autoimmune) or acquired, which can be an acute self-limited illness or a chronic disease that may be induced by medications, including immunotherapy such as monoclonal antibodies (mAbs). Daratum...
Source: Oncology (Williston Park, N.Y.) - October 25, 2023 Category: Cancer & Oncology Authors: Ludovic Saba Kevin S Landau Silvia Bunting Chakra P Chaulagain Source Type: research

Secondary Pure Red Cell Aplasia During Daratumumab/ Hyaluronidase Therapy for Multiple Myeloma
Oncology (Williston Park). 2023 Oct 10;37(10):419-424. doi: 10.46883/2023.25921006.ABSTRACTPredominantly autoimmune in origin, severe normochromic, normocytic anemia with reticulocytopenia in the setting of the normal production of leukocytes and megakaryocytic lineages is known as pure red cell aplasia (PRCA), which is unlike aplastic anemia in which all lineages are affected due to a stem cell defect. PRCA can be primary (such as autoimmune) or acquired, which can be an acute self-limited illness or a chronic disease that may be induced by medications, including immunotherapy such as monoclonal antibodies (mAbs). Daratum...
Source: Oncology (Williston Park, N.Y.) - October 25, 2023 Category: Cancer & Oncology Authors: Ludovic Saba Kevin S Landau Silvia Bunting Chakra P Chaulagain Source Type: research