Granulocyte transfusions in severe aplastic anemia
Haematologica. 2023 Dec 7. doi: 10.3324/haematol.2023.283826. Online ahead of print.ABSTRACTPatients with severe aplastic anemia (SAA) are at high risk for morbidity and mortality due to severe infections. We aimed to characterize the role of granulocyte transfusion (GT) in SAA. Primary outcomes were survival from first GT, including overall survival (OS) at last follow up, survival to discharge, and receipt of HSCT. Secondary outcomes included evaluation of clinical response at 7 and 30 days after GT initiation based on a clinical scoring system incorporating microbiological and radiographic response. Twenty-eight SAA pat...
Source: Haematologica - December 7, 2023 Category: Hematology Authors: Roma V Rajput Vaani Shah Ruba N Shalhoub Kamille West-Mitchell Nu Ri Cha Cathy Conry-Cantilena Susan F Leitman David J Young Brian Wells Georg Aue Cynthia E Dunbar Bhavisha A Patel Richard W Childs Neal S Young Colin O Wu Emma M Groarke Shelley S Kalsi Source Type: research
Granulocyte transfusions in severe aplastic anemia
Haematologica. 2023 Dec 7. doi: 10.3324/haematol.2023.283826. Online ahead of print.ABSTRACTPatients with severe aplastic anemia (SAA) are at high risk for morbidity and mortality due to severe infections. We aimed to characterize the role of granulocyte transfusion (GT) in SAA. Primary outcomes were survival from first GT, including overall survival (OS) at last follow up, survival to discharge, and receipt of HSCT. Secondary outcomes included evaluation of clinical response at 7 and 30 days after GT initiation based on a clinical scoring system incorporating microbiological and radiographic response. Twenty-eight SAA pat...
Source: Haematologica - December 7, 2023 Category: Hematology Authors: Roma V Rajput Vaani Shah Ruba N Shalhoub Kamille West-Mitchell Nu Ri Cha Cathy Conry-Cantilena Susan F Leitman David J Young Brian Wells Georg Aue Cynthia E Dunbar Bhavisha A Patel Richard W Childs Neal S Young Colin O Wu Emma M Groarke Shelley S Kalsi Source Type: research
Granulocyte transfusions in severe aplastic anemia
Haematologica. 2023 Dec 7. doi: 10.3324/haematol.2023.283826. Online ahead of print.ABSTRACTPatients with severe aplastic anemia (SAA) are at high risk for morbidity and mortality due to severe infections. We aimed to characterize the role of granulocyte transfusion (GT) in SAA. Primary outcomes were survival from first GT, including overall survival (OS) at last follow up, survival to discharge, and receipt of HSCT. Secondary outcomes included evaluation of clinical response at 7 and 30 days after GT initiation based on a clinical scoring system incorporating microbiological and radiographic response. Twenty-eight SAA pat...
Source: Haematologica - December 7, 2023 Category: Hematology Authors: Roma V Rajput Vaani Shah Ruba N Shalhoub Kamille West-Mitchell Nu Ri Cha Cathy Conry-Cantilena Susan F Leitman David J Young Brian Wells Georg Aue Cynthia E Dunbar Bhavisha A Patel Richard W Childs Neal S Young Colin O Wu Emma M Groarke Shelley S Kalsi Source Type: research
Granulocyte transfusions in severe aplastic anemia
Haematologica. 2023 Dec 7. doi: 10.3324/haematol.2023.283826. Online ahead of print.ABSTRACTPatients with severe aplastic anemia (SAA) are at high risk for morbidity and mortality due to severe infections. We aimed to characterize the role of granulocyte transfusion (GT) in SAA. Primary outcomes were survival from first GT, including overall survival (OS) at last follow up, survival to discharge, and receipt of HSCT. Secondary outcomes included evaluation of clinical response at 7 and 30 days after GT initiation based on a clinical scoring system incorporating microbiological and radiographic response. Twenty-eight SAA pat...
Source: Haematologica - December 7, 2023 Category: Hematology Authors: Roma V Rajput Vaani Shah Ruba N Shalhoub Kamille West-Mitchell Nu Ri Cha Cathy Conry-Cantilena Susan F Leitman David J Young Brian Wells Georg Aue Cynthia E Dunbar Bhavisha A Patel Richard W Childs Neal S Young Colin O Wu Emma M Groarke Shelley S Kalsi Source Type: research
Granulocyte transfusions in severe aplastic anemia
Haematologica. 2023 Dec 7. doi: 10.3324/haematol.2023.283826. Online ahead of print.ABSTRACTPatients with severe aplastic anemia (SAA) are at high risk for morbidity and mortality due to severe infections. We aimed to characterize the role of granulocyte transfusion (GT) in SAA. Primary outcomes were survival from first GT, including overall survival (OS) at last follow up, survival to discharge, and receipt of HSCT. Secondary outcomes included evaluation of clinical response at 7 and 30 days after GT initiation based on a clinical scoring system incorporating microbiological and radiographic response. Twenty-eight SAA pat...
Source: Haematologica - December 7, 2023 Category: Hematology Authors: Roma V Rajput Vaani Shah Ruba N Shalhoub Kamille West-Mitchell Nu Ri Cha Cathy Conry-Cantilena Susan F Leitman David J Young Brian Wells Georg Aue Cynthia E Dunbar Bhavisha A Patel Richard W Childs Neal S Young Colin O Wu Emma M Groarke Shelley S Kalsi Source Type: research
Granulocyte transfusions in severe aplastic anemia
Haematologica. 2023 Dec 7. doi: 10.3324/haematol.2023.283826. Online ahead of print.ABSTRACTPatients with severe aplastic anemia (SAA) are at high risk for morbidity and mortality due to severe infections. We aimed to characterize the role of granulocyte transfusion (GT) in SAA. Primary outcomes were survival from first GT, including overall survival (OS) at last follow up, survival to discharge, and receipt of HSCT. Secondary outcomes included evaluation of clinical response at 7 and 30 days after GT initiation based on a clinical scoring system incorporating microbiological and radiographic response. Twenty-eight SAA pat...
Source: Haematologica - December 7, 2023 Category: Hematology Authors: Roma V Rajput Vaani Shah Ruba N Shalhoub Kamille West-Mitchell Nu Ri Cha Cathy Conry-Cantilena Susan F Leitman David J Young Brian Wells Georg Aue Cynthia E Dunbar Bhavisha A Patel Richard W Childs Neal S Young Colin O Wu Emma M Groarke Shelley S Kalsi Source Type: research
Granulocyte transfusions in severe aplastic anemia
Haematologica. 2023 Dec 7. doi: 10.3324/haematol.2023.283826. Online ahead of print.ABSTRACTPatients with severe aplastic anemia (SAA) are at high risk for morbidity and mortality due to severe infections. We aimed to characterize the role of granulocyte transfusion (GT) in SAA. Primary outcomes were survival from first GT, including overall survival (OS) at last follow up, survival to discharge, and receipt of HSCT. Secondary outcomes included evaluation of clinical response at 7 and 30 days after GT initiation based on a clinical scoring system incorporating microbiological and radiographic response. Twenty-eight SAA pat...
Source: Haematologica - December 7, 2023 Category: Hematology Authors: Roma V Rajput Vaani Shah Ruba N Shalhoub Kamille West-Mitchell Nu Ri Cha Cathy Conry-Cantilena Susan F Leitman David J Young Brian Wells Georg Aue Cynthia E Dunbar Bhavisha A Patel Richard W Childs Neal S Young Colin O Wu Emma M Groarke Shelley S Kalsi Source Type: research
Granulocyte transfusions in severe aplastic anemia
Haematologica. 2023 Dec 7. doi: 10.3324/haematol.2023.283826. Online ahead of print.ABSTRACTPatients with severe aplastic anemia (SAA) are at high risk for morbidity and mortality due to severe infections. We aimed to characterize the role of granulocyte transfusion (GT) in SAA. Primary outcomes were survival from first GT, including overall survival (OS) at last follow up, survival to discharge, and receipt of HSCT. Secondary outcomes included evaluation of clinical response at 7 and 30 days after GT initiation based on a clinical scoring system incorporating microbiological and radiographic response. Twenty-eight SAA pat...
Source: Haematologica - December 7, 2023 Category: Hematology Authors: Roma V Rajput Vaani Shah Ruba N Shalhoub Kamille West-Mitchell Nu Ri Cha Cathy Conry-Cantilena Susan F Leitman David J Young Brian Wells Georg Aue Cynthia E Dunbar Bhavisha A Patel Richard W Childs Neal S Young Colin O Wu Emma M Groarke Shelley S Kalsi Source Type: research
Granulocyte transfusions in severe aplastic anemia
Haematologica. 2023 Dec 7. doi: 10.3324/haematol.2023.283826. Online ahead of print.ABSTRACTPatients with severe aplastic anemia (SAA) are at high risk for morbidity and mortality due to severe infections. We aimed to characterize the role of granulocyte transfusion (GT) in SAA. Primary outcomes were survival from first GT, including overall survival (OS) at last follow up, survival to discharge, and receipt of HSCT. Secondary outcomes included evaluation of clinical response at 7 and 30 days after GT initiation based on a clinical scoring system incorporating microbiological and radiographic response. Twenty-eight SAA pat...
Source: Haematologica - December 7, 2023 Category: Hematology Authors: Roma V Rajput Vaani Shah Ruba N Shalhoub Kamille West-Mitchell Nu Ri Cha Cathy Conry-Cantilena Susan F Leitman David J Young Brian Wells Georg Aue Cynthia E Dunbar Bhavisha A Patel Richard W Childs Neal S Young Colin O Wu Emma M Groarke Shelley S Kalsi Source Type: research
Correction to: Reduced regulatory effects of bone marrow-derived mesenchymal stem cells on activated T lymphocytes and Th1/Th2 cytokine secretion in children with aplastic anemia
(Source: Clinical and Experimental Medicine)
Source: Clinical and Experimental Medicine - December 6, 2023 Category: Research Source Type: research
