Film dressings from Thai mango seed kernel extracts versus nanocrystalline silver dressings in antibacterial properties
Conclusion: 20%, 30%, and 40% of MSK film dressing is nearly as effective as nanocrystalline silver dressing. Therefore, it has the potential to be an alternative antibacterial dressing and is suitable for wounds with low exudate levels.PMID:38606395 | PMC:PMC11006813 | DOI:10.3389/jpps.2024.12674 (Source: Journal of Pharmacy and Pharmaceutical Sciences)
Source: Journal of Pharmacy and Pharmaceutical Sciences - April 12, 2024 Category: Drugs & Pharmacology Authors: Sukhontha Hasatsri Bajaree Jantrapanukorn Source Type: research

The bioequivalence study design recommendations for immediate-release solid oral dosage forms in the international pharmaceutical regulators programme participating regulators and organisations: differences and commonalities
The objective of this article is to describe the recommendations from participating Bioequivalence Working Group for Generics (BEWGG) members of the International Pharmaceutical Regulators Programme (IPRP) regarding the conduct and acceptance criteria for BE studies of immediate release solid oral dosage forms. A survey was conducted among BEWGG members regarding their BE recommendations and requirements related to study subjects, study design, sample size, single or multiple dose administration, study conditions (fasting or fed), analyte to be measured, selection of product strength, drug content, handling of endogenous s...
Source: Journal of Pharmacy and Pharmaceutical Sciences - April 5, 2024 Category: Drugs & Pharmacology Authors: Eduardo Agostinho Freitas Fernandes Joy van Oudtshoorn Andrew Tam Liliana Carolina Ar évalo González Erwin Guzm án Aurela Henrike Potthast Katalina Mettke Ryosuke Kuribayashi Kohei Shimojo Miho Kasuga L ázaro Morales Zulema Rodr íguez Ben Jones Choon Source Type: research

Recent progress of polymeric microneedle-assisted long-acting transdermal drug delivery
J Pharm Pharm Sci. 2024 Mar 20;27:12434. doi: 10.3389/jpps.2024.12434. eCollection 2024.ABSTRACTMicroneedle (MN)-assisted drug delivery technology has gained increasing attention over the past two decades. Its advantages of self-management and being minimally invasive could allow this technology to be an alternative to hypodermic needles. MNs can penetrate the stratum corneum and deliver active ingredients to the body through the dermal tissue in a controlled and sustained release. Long-acting polymeric MNs can reduce administration frequency to improve patient compliance and therapeutic outcomes, especially in the managem...
Source: Journal of Pharmacy and Pharmaceutical Sciences - April 4, 2024 Category: Drugs & Pharmacology Authors: Fanda Meng Xinyu Qiao Chenglong Xin Xiaoli Ju Meilin He Source Type: research

Formulating biopharmaceuticals using three-dimensional printing
J Pharm Pharm Sci. 2024 Mar 15;27:12797. doi: 10.3389/jpps.2024.12797. eCollection 2024.ABSTRACTAdditive manufacturing, commonly referred to as three-dimensional (3D) printing, has the potential to initiate a paradigm shift in the field of medicine and drug delivery. Ever since the advent of the first-ever United States Food and Drug Administration (US FDA)-approved 3D printed tablet, there has been an increased interest in the application of this technology in drug delivery and biomedical applications. 3D printing brings us one step closer to personalized medicine, hence rendering the "one size fits all" concept in drug d...
Source: Journal of Pharmacy and Pharmaceutical Sciences - April 1, 2024 Category: Drugs & Pharmacology Authors: Alistair K C Chan Nehil Ranjitham Gopalakrishnan Yannick Leandre Traore Emmanuel A Ho Source Type: research

Real-world data: a comprehensive literature review on the barriers, challenges, and opportunities associated with their inclusion in the health technology assessment process
Conclusion: This study highlights the intricate global landscape of RWD and RWE acceptance in HTA. Recognizing regional nuances, addressing methodological challenges, and promoting collaboration are pivotal, among others, for leveraging RWD and RWE effectively in healthcare decision-making.PMID:38481726 | PMC:PMC10932954 | DOI:10.3389/jpps.2024.12302 (Source: Journal of Pharmacy and Pharmaceutical Sciences)
Source: Journal of Pharmacy and Pharmaceutical Sciences - March 14, 2024 Category: Drugs & Pharmacology Authors: Konstantinos Zisis Elpida Pavi Mary Geitona Kostas Athanasakis Source Type: research