Molecules, Vol. 27, Pages 5187: Green Extraction of Annatto Seed Oily Extract and Its Use as a Pharmaceutical Material for the Production of Lipid Nanoparticles
. Ferreira
This work developd nanomaterials formulated from annatto seed oily extract (ASE), myristic acid (tetradecanoic acid), and their fatty acid esters. The annatto seed oily extract was obtained using only soybean oil (ASE + SO) and Brazil nut oil (ASE + BNO). The UV/VIS analysis of the oily extracts showed three characteristic peaks of the bixin molecule at 430, 456 and 486 nm. The lipid nanoparticles obtained using myristic acid and ASE + BNO or only BNO showed better results than the oil soybean extract, i.e., the particle size was <200 nm, PDI value was in the range of 0.2–0.3, and ha...
Source: Molecules - August 15, 2022 Category: Chemistry Authors: S ônia do Socorro do C. Oliveira Edmilson dos S. Sarmento Victor H. Marinho Rayanne R. Pereira Luis P. Fonseca Irlon M. Ferreira Tags: Article Source Type: research
Revegetation of an area impacted by iron ore tailings: evaluating fertilization alternatives in native pioneer and secondary trees
Environ Sci Pollut Res Int. 2022 Aug 11. doi: 10.1007/s11356-022-22376-3. Online ahead of print.ABSTRACTThe iron ore tailings released into the Rio Doce basin after the Fundão dam collapse (Brazil), suppressed a large extent of local vegetation. The use of native species and appropriate fertilization techniques, with less economic and environmental impact, must be considered in the process for the restoration of affected areas by the tailings. For this purpose, six native tree species, pioneer (Anadenanthera colubrina, Bixa orellana, and Peltophorum dubium) and secondary (Cedrela fissilis, Handroanthus impetiginosus, and ...
Source: Environmental Science and Pollution Research International - August 10, 2022 Category: Environmental Health Authors: Talita Raissa Silva Santos Jessyca Adelle Silva Santos Eduardo Gusm ão Pereira Queila Souza Garcia Source Type: research
Molecules, Vol. 27, Pages 2138: Organic Electronics from Nature: Computational Investigation of the Electronic and Optical Properties of the Isomers of Bixin and Norbixin Present in the Achiote Seeds
Filho
Organic compounds have been employed in developing new green energy solutions with good cost-efficiency compromise, such as photovoltaics. The light-harvesting process in these applications is a crucial feature that still needs improvements. Here, we studied natural dyes to propose an alternative for enhancing the light-harvesting capability of photovoltaics. We performed density functional theory calculations to investigate the electronic and optical properties of the four natural dyes found in achiote seeds (Bixa orellana L.). Different DFT functionals, and basis sets, were used to calculate the electronic and...
Source: Molecules - March 25, 2022 Category: Chemistry Authors: Igo T ôrres Lima Josiel da Silva Crispim Olimpio Pereira de S á Neto Rafael Tim óteo de Sousa Júnior Luiz Ant ônio Ribeiro Júnior Dem étrio Antonio da Silva Filho Tags: Article Source Type: research
Bixin Prevents Colorectal Cancer Development through AMPK-Activated Endoplasmic Reticulum Stress
In conclusion, this study indicated that Bixin treatment inhibits the progression of CRC through activating the AMPK/PERK/eIF-2α pathway, providing a novel potential strategy for clinical prevention of CRC.PMID:35252457 | PMC:PMC8894005 | DOI:10.1155/2022/9329151 (Source: Biomed Res)
Source: Biomed Res - March 7, 2022 Category: Research Authors: Yunfeng Qiu Changfeng Li Bin Zhang Source Type: research
Bixin Prevents Colorectal Cancer Development through AMPK-Activated Endoplasmic Reticulum Stress
In conclusion, this study indicated that Bixin treatment inhibits the progression of CRC through activating the AMPK/PERK/eIF-2α pathway, providing a novel potential strategy for clinical prevention of CRC.PMID:35252457 | PMC:PMC8894005 | DOI:10.1155/2022/9329151 (Source: Cell Research)
Source: Cell Research - March 7, 2022 Category: Cytology Authors: Yunfeng Qiu Changfeng Li Bin Zhang Source Type: research
Molecules, Vol. 27, Pages 1584: Potential of the Compounds from Bixa orellana Purified Annatto Oil and Its Granules (Chronic & reg;) against Dyslipidemia and Inflammatory Diseases: In Silico Studies with Geranylgeraniol and Tocotrienols
This study aimed to evaluate possible mechanisms of action that could be underlying the activities of these molecules. For this, in silico approaches such as ligand topology (PASS and SEA servers) and molecular docking with the software GOLD were used. Additionally, we screened some pharmacokinetic and toxicological parameters using the servers PreADMET, SwissADME, and ProTox-II. The results corroborate the antidyslipidemia and anti-inflammatory activities of geranylgeraniol and tocotrienols. Notably, some new mechanisms of action were predicted to be potentially underlying the activities of these compounds, including inhi...
Source: Molecules - February 28, 2022 Category: Chemistry Authors: Mateus Alves Batista Abrah ão Victor Tavares de Lima Teixeira dos Santos Aline Lopes do Nascimento Luiz Fernando Moreira Indira Ramos Senna Souza Heitor Ribeiro da Silva Arlindo C ésar Matias Pereira Lorane Izabel da Silva Hage-Melim Jos é Carlos Tavar Tags: Article Source Type: research
Evaluation of a Zingiber officinale and Bixa orellana
Supplement on the Gut Microbiota of Male Athletes: A Randomized
Placebo-Controlled Trial
Planta Med DOI: 10.1055/a-1671-5766The gut microbiota has emerged as a factor that influences exercise performance
and recovery. The present study aimed to test the effect of a polyherbal
supplement containing ginger and annatto called “ReWin(d)” on the gut microbiota
of recreational athletes in a pilot, randomized, triple-blind,
placebo-controlled trial. Thirty-four participants who practice physical
activity at least three times weekly were randomly allocated to two groups, a
ReWin(d) group or a maltodextrin (placebo) group. We evaluated the gut
microbiota, the production of short-c...
Source: Planta Medica - February 28, 2022 Category: Drugs & Pharmacology Authors: Dom ínguez-Balmaseda, Diego Bressa, Carlo Fern ández-Romero, Arantxa de Lucas, Beatriz P érez-Ruiz, Margarita San Juan, Alejandro F. Roller, Marc Issaly, Nicolas Larrosa, Mar Tags: Original Papers Source Type: research
Low-frequency ultrasound-assisted esterification of Bixa orellana L. seed starch with octenyl succinic anhydride
This study aimed to evaluate the impact of the ultrasound intensity (0, 5, 10, and 20 W/cm2) on the esterification of annatto (Bixa orellana L.) seed starch with octenyl succinic anhydride (OSA) employing a short processing time (5 min) to produce a novel emulsifier. OSA-esterified annatto seed starches were examined according to their degree of substitution (DS), amylose content, granule size distribution, microstructure, and X-ray diffractogram. Also, the performance of the OSA-modified annatto seed starch to stabilize colloidal systems was compared to commercial samples of OSA-modified starches. For this, annatto seed o...
Source: International Journal of Biological Macromolecules - February 23, 2022 Category: Biochemistry Authors: Eric Keven Silva Ana Gabriela da S Anthero Lucas B Emerick Giovani L Zabot Miriam D Hubinger Maria Angela A Meireles Source Type: research
Low-frequency ultrasound-assisted esterification of Bixa orellana L. seed starch with octenyl succinic anhydride
This study aimed to evaluate the impact of the ultrasound intensity (0, 5, 10, and 20 W/cm2) on the esterification of annatto (Bixa orellana L.) seed starch with octenyl succinic anhydride (OSA) employing a short processing time (5 min) to produce a novel emulsifier. OSA-esterified annatto seed starches were examined according to their degree of substitution (DS), amylose content, granule size distribution, microstructure, and X-ray diffractogram. Also, the performance of the OSA-modified annatto seed starch to stabilize colloidal systems was compared to commercial samples of OSA-modified starches. For this, annatto seed o...
Source: International Journal of Biological Macromolecules - February 23, 2022 Category: Biochemistry Authors: Eric Keven Silva Ana Gabriela da S Anthero Lucas B Emerick Giovani L Zabot Miriam D Hubinger Maria Angela A Meireles Source Type: research
< em > Bixa orellana < /em > L. carotenoids: antiproliferative activity on human lung cancer, breast cancer, and cervical cancer cells < em > in vitro < /em >
Nat Prod Res. 2022 Feb 8:1-7. doi: 10.1080/14786419.2022.2036144. Online ahead of print.ABSTRACTEmerging evidence on the potential pro-oxidant effect of carotenoids provokes apoptosis of cancer cells. Bixa orellana L. is native to Central and South America, interestingly, is also cultivated worldwide. Apo-carotenoids present in B. orellana L. are mainly dominated by bixin and norbixin and demonstrate fundamental antioxidant activity. Anti-proliferative activity on human cancer cells is rarely investigated. We isolated bixin from B. orellana L. found in the island of Java using Ultra-Fast Liquid Chromatography and confirmed...
Source: Natural Product Research - February 8, 2022 Category: Biochemistry Authors: Lia Kusmita Yuvianti Dwi Franyoto Mutmainah Mutmainah Ika Puspitaningrum Agustina D R Nurcahyanti Source Type: research
< em > Bixa orellana < /em > L. carotenoids: antiproliferative activity on human lung cancer, breast cancer, and cervical cancer cells < em > in vitro < /em >
Nat Prod Res. 2022 Feb 8:1-7. doi: 10.1080/14786419.2022.2036144. Online ahead of print.ABSTRACTEmerging evidence on the potential pro-oxidant effect of carotenoids provokes apoptosis of cancer cells. Bixa orellana L. is native to Central and South America, interestingly, is also cultivated worldwide. Apo-carotenoids present in B. orellana L. are mainly dominated by bixin and norbixin and demonstrate fundamental antioxidant activity. Anti-proliferative activity on human cancer cells is rarely investigated. We isolated bixin from B. orellana L. found in the island of Java using Ultra-Fast Liquid Chromatography and confirmed...
Source: Cell Research - February 8, 2022 Category: Cytology Authors: Lia Kusmita Yuvianti Dwi Franyoto Mutmainah Mutmainah Ika Puspitaningrum Agustina D R Nurcahyanti Source Type: research
< em > Bixa orellana < /em > L. carotenoids: antiproliferative activity on human lung cancer, breast cancer, and cervical cancer cells < em > in vitro < /em >
Nat Prod Res. 2022 Feb 8:1-7. doi: 10.1080/14786419.2022.2036144. Online ahead of print.ABSTRACTEmerging evidence on the potential pro-oxidant effect of carotenoids provokes apoptosis of cancer cells. Bixa orellana L. is native to Central and South America, interestingly, is also cultivated worldwide. Apo-carotenoids present in B. orellana L. are mainly dominated by bixin and norbixin and demonstrate fundamental antioxidant activity. Anti-proliferative activity on human cancer cells is rarely investigated. We isolated bixin from B. orellana L. found in the island of Java using Ultra-Fast Liquid Chromatography and confirmed...
Source: Natural Product Research - February 8, 2022 Category: Biochemistry Authors: Lia Kusmita Yuvianti Dwi Franyoto Mutmainah Mutmainah Ika Puspitaningrum Agustina D R Nurcahyanti Source Type: research
Liquid chromatography coupled to Venturi easy ambient sonic spray ionization mass spectrometry
Talanta. 2022 Feb 1;238(Pt 1):123004. doi: 10.1016/j.talanta.2021.123004. Epub 2021 Oct 30.ABSTRACTVenturi easy ambient sonic spray ionization (V-EASI) is a soft ambient ionization (AI) source that has the advantages of being suitable to the analysis of samples in solution (differently from the majority of AI sources), performing self-pumping, voltage- and heat-free ionization, and requiring minimum or no sample preparation. Since this ionization technique has not been fully explored, the present study provides a proof of principle of the coupling of liquid chromatography to mass spectrometry (LC-MS) using V-EASI as the in...
Source: Talanta - December 3, 2021 Category: Chemistry Authors: Luan Felipe Campos Oliveira David Ulisses Tega Marcos Nogueira Eberlin Alessandra Sussulini Source Type: research
Liquid chromatography coupled to Venturi easy ambient sonic spray ionization mass spectrometry
Talanta. 2022 Feb 1;238(Pt 1):123004. doi: 10.1016/j.talanta.2021.123004. Epub 2021 Oct 30.ABSTRACTVenturi easy ambient sonic spray ionization (V-EASI) is a soft ambient ionization (AI) source that has the advantages of being suitable to the analysis of samples in solution (differently from the majority of AI sources), performing self-pumping, voltage- and heat-free ionization, and requiring minimum or no sample preparation. Since this ionization technique has not been fully explored, the present study provides a proof of principle of the coupling of liquid chromatography to mass spectrometry (LC-MS) using V-EASI as the in...
Source: Talanta - December 3, 2021 Category: Chemistry Authors: Luan Felipe Campos Oliveira David Ulisses Tega Marcos Nogueira Eberlin Alessandra Sussulini Source Type: research
Self-emulsified annatto tocotrienol improves bone histomorphometric parameters in a rat model of oestrogen deficiency through suppression of skeletal sclerostin level and RANKL/OPG ratio
In conclusion, SEAT exerts potential skeletal anabolic properties by increasing bone formation, suppressing sclerostin expression and reducing RANKL/OPG ratio in rats with oestrogen deficiency.PMID:34790038 | PMC:PMC8579289 | DOI:10.7150/ijms.64045 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - November 18, 2021 Category: Biomedical Science Authors: Nur-Vaizura Mohamad Soelaiman Ima-Nirwana Kok-Yong Chin Source Type: research
