Annatto seed hypersensitivity in a pediatric patient.
PMID: 27613468 [PubMed - in process] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - August 31, 2016 Category: Allergy & Immunology Authors: Ramsey NB, Tuano KT, Davis CM, Dillard K, Hanson C Tags: Ann Allergy Asthma Immunol Source Type: research
Annatto seed hypersensitivity in a pediatric patient
Food allergy is of increasing concern and prevalence, particularly in children younger than 5 years who reside in urbanized areas of developed countries.1 In response to this trend, The Food Allergy Labeling and Consumer Protection Act of 2004 (Public Law 108-282, Title II) was passed, requiring that the 10 most common food allergens be listed on nutrition labels. This legislation, although progressive, does not capture other allergens such as food additives that can cause near-fatal reactions.1 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - August 31, 2016 Category: Allergy & Immunology Authors: Nicole B. Ramsey, Karen Thursday S. Tuano, Carla M. Davis, Kristin Dillard, Celine Hanson Tags: Letter Source Type: research
The effect of the carotenoid bixin and annatto seeds on hematological markers and nephrotoxicity in rats subjected to chronic treatment with cisplatin
This study assessed the protective effect of the carotenoid bixin and annatto seeds against possible nephrotoxicity induced with a single peritoneal administration of pharmacological cisplatin in male Wistar rats. After 48 h, the blood cell differential count showed a significant reduction in neutrophil counts in rats that received a diet rich in bixin when compared to the group that received only cisplatin. The use of cisplatin led to an increase in kidney weight. The carotenoid bixin attenuated renal injury, characterized by increased polymorphonuclear infiltration. No protective effect was observed with respect to Annat...
Source: Revista Brasileira de Farmacognosia - August 19, 2016 Category: Drugs & Pharmacology Source Type: research
Food colorants: challenges, opportunities and current desires of agro-industries to ensure consumer expectations and regulatory practices
Publication date: Available online 5 April 2016 Source:Trends in Food Science & Technology Author(s): Natália Martins, Custódio Lobo Roriz, Patricia Morales, Lillian Barros, Isabel C.F.R. Ferreira Background Worldwide consumers seek most delightful and appealing foodstuffs, at the same time they require safer, more nutritious and healthier products. Color is one of the most important organoleptic attributes that directly affects consumers’ acceptance and food selection. Scope and approach The present report aims to provide an extensive approach to the field of food (natural/synthetic) colorants,...
Source: Trends in Food Science and Technology - April 8, 2016 Category: Food Science Source Type: research
Evaluation of Pharmacokinetics, and Bioavailability of Higher Doses of Tocotrienols in Healthy Fed Humans.
CONCLUSIONS: This study has described pharmacokinetics using higher doses of 750 mg/d and 1000 mg/d of δ-tocotrienol. These results confirmed earlier findings that Tmax was 3-4 h for all isomers of tocotrienols and tocopherols except for α-tocopherol (6 h). These higher doses of tocotrienols were found safe in humans and may be useful for treatments of various types of cancer, diabetes, and Alzheimer's disease.
PMID: 27493840 [PubMed - as supplied by publisher] (Source: Journal of Clinical and Experimental Cardiology)
Source: Journal of Clinical and Experimental Cardiology - March 31, 2016 Category: Cardiology Authors: Qureshi AA, Khan DA, Silswal N, Saleem S, Qureshi N Tags: J Clin Exp Cardiolog Source Type: research
Biopolymer-prebiotic carbohydrate blends and their effects on the retention of bioactive compounds and maintenance of antioxidant activity
The objective of this study was to evaluate the use of inulin (IN), a prebiotic carbohydrate without superficial activity, as an encapsulating matrix of lipophilic bioactive compounds. For achieving the encapsulation, IN was associated with biopolymers that present superficial activity: modified starch (HiCap), whey protein isolate (WPI) and gum acacia (GA). Encapsulation was performed through emulsification assisted by ultrasound followed by freeze-drying (FD) process to dry the emulsions. All blends retained geranylgeraniol. GA-IN blend yielded the highest geranylgeraniol retention (96±2wt.%) and entrapment efficiency (...
Source: Carbohydrate Polymers - March 5, 2016 Category: Biomedical Science Source Type: research
Identifying a Carotenoid Cleavage Dioxygenase 4a Gene and Its Efficient Agrobacterium-Mediated Genetic Transformation in Bixa orellana L.
Abstract
Carotenoids are metabolized to apocarotenoids through the pathway catalysed by carotenoid cleavage oxygenases (CCOs). The apocarotenoids are economically important as it is known to have therapeutic as well as industrial applications. For instance, bixin from Bixa orellana and crocin from Crocus sativus are commercially used as a food colourant and cosmetics since prehistoric time. In our present study, CCD4a gene has been identified and isolated from leaves of B. orellana for the first time and named as BoCCD4a; phylogenetic analysis was carried out using CLUSTAL W. From sequence analysis, BoCCD4...
Source: Applied Biochemistry and Biotechnology - February 27, 2016 Category: Biochemistry Authors: Sankari M, Hemachandran H, Anantharaman A, Babu S, Madrid RR, C GP, Fulzele DP, Siva R Tags: Appl Biochem Biotechnol Source Type: research
Annatto Tocotrienol Induces a Cytotoxic Effect on Human Prostate Cancer PC3 Cells via the Simultaneous Inhibition of Src and Stat3.
Authors: Sugahara R, Sato A, Uchida A, Shiozawa S, Sato C, Virgona N, Yano T
Abstract
Prostate cancer is one of the most frequently occurring cancers and often acquires the potential of androgen-independent growth as a malignant phenotype. Androgen-independent prostate cancer has severe chemoresistance towards conventional chemotherapeutic agents, so a new treatment approach is required for curing such prostate cancer. In this context, the present study was undertaken to check if annatto tocotrienol (main component δ-tocotrienol) could suppress cell growth in human prostate cancer (PC3, androgen-independe...
Source: Journal of Nutritional Science and Vitaminology - February 17, 2016 Category: Nutrition Tags: J Nutr Sci Vitaminol (Tokyo) Source Type: research
Beneficial effect of medicinal plants on the contractility of post-hypoxic isolated guinea pig atria - Potential implications for the treatment of ischemic-reperfusion injury.
Conclusions Preparations from A. muricata and B. orellana may possess positive-inotropic properties which may improve the contractility of the post-hypoxic myocardium. Studies to assess their usefulness in ischemic-reperfusion injury are warranted.
PMID: 26730936 [PubMed - as supplied by publisher] (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - February 16, 2016 Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research
Fixed Drug Eruption due to Achiote Dye
This report adds to the small body of available literature on non-pharmacological fixed hypersensitivity eruptions and illustrates an effective approach to the management of such a presentation when history is not immediately revealing.Case Rep Dermatol 2016;8:14-18 (Source: Case Reports in Dermatology)
Source: Case Reports in Dermatology - January 28, 2016 Category: Dermatology Source Type: research
Can lutein replace annatto in the manufacture of Prato cheese?
Publication date: May 2016 Source:LWT - Food Science and Technology, Volume 68 Author(s): Denise Sobral, Renata Golin Bueno Costa, Gisela Magalhães Machado, Junio Cesar Jacinto de Paula, Vanessa Aglaê Martins Teodoro, Natália Moreira Nunes, Ana Clarissa dos Santos Pires, Maximiliano Soares Pinto Prato cheese is a Brazilian yellow-orange cheese traditionally colored with annatto. However, the aim of this study was to replace annatto with lutein, a natural yellow food pigment with potent antioxidant properties. Accordingly, we evaluated the maintenance of antioxidant activity of two concentrations of l...
Source: LWT Food Science and Technology - January 11, 2016 Category: Food Science Source Type: research
Ultrasound-assisted encapsulation of annatto seed oil: Whey protein isolate versus modified starch
The objective of this study was to compare the performance of whey protein isolate (WPI) and modified starch (SF) based on their surface properties as adsorbents in the oil–water interface aiming the encapsulation of the annatto seed oil by ultrasound-assisted emulsification. We also analyzed the influence of WPI and SF on technological quality of the microparticles formed from the respective emulsions by freeze-drying (FD) and spray-drying (SD). The effects of ultrasonication power and processing time were assessed by the droplet size of the dispersed phase and creaming stability. The finer emulsions obtained with the e...
Source: Food Hydrocolloids - December 22, 2015 Category: Food Science Source Type: research
Phytochemistry, Biological Activities and Potential of Annatto in Natural Colorant Production for Industrial Applications-A Review
Publication date: Available online 30 November 2015 Source:Journal of Advanced Research Author(s): Shahid-ul- Islam, Luqman Jameel Rather, Faqeer Mohammad Bixa orellana commonly known as annatto is one of the oldest known natural dye yielding plant native to Central and South America. Various parts of annatto have been widely used in the traditional medical system for prevention and treatment of a wide number of health disorders. The plethora of traditional uses has encouraged researchers to identify and isolate phytochemicals from all parts of this plant. Carotenoids, apocarotenoids, terpenes, terpenoids, stero...
Source: Journal of Advanced Research - December 2, 2015 Category: Research Source Type: research
Induction of apoptosis by apocarotenoids in B16 melanoma cells through ROS-mediated mitochondrial-dependent pathway
This study explores the mechanism of apocarotenoids (bixin and norbixin) on the aggressive B16 murine melanoma as an anti-cancer agent. The apocarotenoids inhibited the cell viability of B16 melanoma in a time- and concentration-dependent manner. Apocarotenoids markedly induced cell morphology change, nuclear condensation, DNA fragmentation, and mitochondrial dysfunction through the depletion of glutathione activity, and also induced reactive oxygen species (ROS) generation. Furthermore, apocarotenoids effectively enhanced sub-G1 population and also activated caspase 9 and caspase 3 activities. It decreased and increased t...
Source: Journal of Functional Foods - November 23, 2015 Category: Nutrition Source Type: research
Ultrasound-assisted encapsulation of annatto seed oil: Retention and release of a bioactive compound with functional activities
Publication date: Available online 20 October 2015 Source:Food Research International Author(s): Eric Keven Silva, Giovani L. Zabot, M. Angela, A. Meireles This paper brings forward the encapsulation of annatto seed oil (rich in geranylgeraniol) assisted by high intensity ultrasound using gum Arabic (GA) as stabilizing agent. We studied the effects of time (min) and ultrasonication power (W) over the emulsions characteristics. After forming microparticles from the best emulsion using freeze-drying (FD) and spray-drying (SD) techniques, we evaluated particle size distribution, moisture, water activity, surface o...
Source: Food Research International - October 22, 2015 Category: Food Science Source Type: research
