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Gene structure and potential regulation of the lycopene cyclase genes in Bixa orellana L
Physiol Mol Biol Plants. 2023 Oct;29(10):1423-1435. doi: 10.1007/s12298-023-01384-8. Epub 2023 Nov 13.ABSTRACTLycopene cyclases (LCYs) are a key branching point in regulating the carotenoid biosynthesis pathway in plants. Bixa orellana L. is characterized by the presence in its seed of bixin, an apocarotenoid of significant importance in the food, pharmaceutical, and cosmetic industries. Gene analysis provides the opportunity to investigate the LCY gene structure in plant species and its relationship with the synthesis of carotenoids. Coding sequences of the LCY genes were retrieved from a B. orellana genome DNA. Boβ-LCY1...
Source: Mol Biol Cell - December 11, 2023 Category: Molecular Biology Authors: G Rivero-Manzanilla J A Narv áez-Zapata M Aguilar-Espinosa V M Carballo-Uicab R Rivera-Madrid Source Type: research

Application of different concentrations of the natural dye potassium norbixinate (annatto) in polyamide 6.6 fabrics
Nat Prod Res. 2023 Nov 11:1-8. doi: 10.1080/14786419.2023.2280178. Online ahead of print.ABSTRACTPolyamide fabrics were dyed with concentrations ranging from 4% to 0.25% (o.w.f.) of the natural dye, potassium norbixinate (annatto). The exhaustion, chromatic coordinates, colouristic intensity (K/S), and fastness to washing and rubbing were evaluated. The natural dye was characterised, and its maximum absorption peaks were identified at 452 nm and 482 nm through UV-vis scanning. Its main chemical groups were identified by FTIR-ATR. All dyeings exhibited high exhaustion percentage, with a maximum of 98.4% for 1% dye concentra...
Source: Natural Product Research - November 11, 2023 Category: Biochemistry Authors: Marcel Jefferson Gon çalves Ariane Canuto Veiga de Oliveira Am ábile Colla Prando Carolina Krebs de Souza Rita de Cassia Siqueira Curto Valle Ivonete Oliveira Barcellos Lorena Benathar Ballod Tavares Source Type: research

Bixa orellana ethyl acetate fraction and its isolated compound ellagic acid attenuate the progression of MIA-induced osteoarthritis in rat knees
Biomed Pharmacother. 2023 Oct 13;168:115644. doi: 10.1016/j.biopha.2023.115644. Online ahead of print.ABSTRACTOsteoarthritis (OA) is a pathology that is characterized by progressive erosion of articular cartilage. In this context, medicinal plants have become relevant tools regarding their potential role in the prevention and treatment of OA, being safe and effective. The aim of this work was investigate the therapeutic efficacy of the ethyl acetate fraction of Bixa orellana leaves (BoEA) and ellagic acid (ElAc) for the therapeutic treatment of OA induced by monosodium iodoacetate (MIA) in rats. The plant material was extr...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 15, 2023 Category: Drugs & Pharmacology Authors: Luis Ângelo Macêdo Santiago Ana Caroline Santos Ata íde Danilo de Ara újo Morais Aldilene da Silva Lima Nath álya Dos Santos Martins Adriana Vivian Costa Ara újo Dourado Rachel Melo Ribeiro L ídio Gonçalves Lima-Neto Joicy Cortez de S á Sousa Cl Source Type: research

Effect of the Association of Fixed Oils from Abelmoschus esculentus (L.) Moench, Euterpe oleracea Martius, Bixa orellana Linn é and Chronic SM ® on Atherogenic Dyslipidemia in Wistar Rats
This study investigated the effects of treatments with oils from A. esculentus, E. oleracea, B. orellana, and Chronic SM® on Cocos nucifera L. saturated-fat-induced dyslipidemia. The chromatographic profile showed the majority presence of unsaturated fatty acids in the tested oils. The quantification of tocotrienols and geranylgeraniol in OFBO and CHR was obtained. Treatments with OFEO, OFAE, OFBO, and CHR were able to significantly reduce glycemia, as well as hypertriglyceridemia, total cholesterol, and LDL-cholesterol, besides increasing HDL-cholesterol. The treatments inhibited the formation of atheromatous plaques in ...
Source: Atherosclerosis - September 28, 2023 Category: Cardiology Authors: Priscila Faimann Sales Aline Lopes do Nascimento Fernanda Cavalcante Pinheiro Andressa Ketelem Meireles Alberto Abrah ão Victor Tavares de Lima Teixeira Dos Santos Helison de Oliveira Carvalho Gisele Cust ódio de Souza Jos é Carlos Tavares Carvalho Source Type: research

Molecules, Vol. 28, Pages 6689: Effect of the Association of Fixed Oils from Abelmoschus esculentus (L.) Moench, Euterpe oleracea Martius, Bixa orellana Linn & eacute; and Chronic SM & reg; on Atherogenic Dyslipidemia in Wistar Rats
This study investigated the effects of treatments with oils from A. esculentus, E. oleracea, B. orellana, and Chronic SM&reg; on Cocos nucifera L. saturated-fat-induced dyslipidemia. The chromatographic profile showed the majority presence of unsaturated fatty acids in the tested oils. The quantification of tocotrienols and geranylgeraniol in OFBO and CHR was obtained. Treatments with OFEO, OFAE, OFBO, and CHR were able to significantly reduce glycemia, as well as hypertriglyceridemia, total cholesterol, and LDL-cholesterol, besides increasing HDL-cholesterol. The treatments inhibited the formation of atheromatous ...
Source: Molecules - September 19, 2023 Category: Chemistry Authors: Priscila Faimann Sales Aline Lopes do Nascimento Fernanda Cavalcante Pinheiro Andressa Ketelem Meireles Alberto Abrah ão Victor Tavares de Lima Teixeira dos Santos Helison de Oliveira Carvalho Gisele Cust ódio de Souza Jos é Carlos Tavares Carvalho Tags: Article Source Type: research

Detection of botanical adulterants in saffron powder
Anal Bioanal Chem. 2023 Aug 17. doi: 10.1007/s00216-023-04853-x. Online ahead of print.ABSTRACTSaffron is a unique spice obtained by drying stigmas of saffron flowers (Crocus sativus L.). Due to its high price, economically motivated adulteration occurs relatively often. The presented study aimed to develop an effective strategy for the detection of the following potential botanical adulterants used for a saffron substitution or dilution: safflower (Carthamus tinctorius L.), calendula (Calendula officinalis L.), turmeric (Curcuma longa L.), achiote (Bixa orellana L.), red pepper (Capsicum spp.), mountain arnica (Arnica mon...
Source: Analytical and Bioanalytical Chemistry - August 16, 2023 Category: Chemistry Authors: Jana Ryparova Kvirencova Klara Navratilova Vojtech Hrbek Jana Hajslova Source Type: research

A review of the chemistry and biological activities of natural colorants, dyes, and pigments: challenges, and opportunities for food, cosmetics, and pharmaceutical application
This article reviewed the chemistry and therapeutic potentials of over 570 colored molecules from plants, fungi, bacteria, insects, algae, and marine sources. Moreover, related biological activities, advanced extraction, and identification approaches were reviewed. A variety of biological activities, including cytotoxicity against cancer cells, antioxidant, anti-inflammatory, wound healing, anti-microbial, antiviral, and anti-protozoal activities, have been reported for different pigments. Considering their structural backbone, they were classified as naphthoquinones, carotenoids, flavonoids, xanthones, anthocyanins, benzo...
Source: Chemistry and Biodiversity - July 20, 2023 Category: Biochemistry Authors: Ardalan Pasdaran Maryam Zare Azar Hamedi Azadeh Hamedi Source Type: research

The role of bixin as antioxidant, anti-inflammatory, anticancer, and skin protecting natural product extracted from Bixa orellana L
Fitoterapia. 2023 Jul 14:105612. doi: 10.1016/j.fitote.2023.105612. Online ahead of print.ABSTRACTSince long, medicinal plants or herbs are being used in different traditional treatment systems as therapeutic agents to treat a variety of illnesses. Bixa orellana L., an medicinal plant (family: Bixaceae), is an Ayurvedic herb used to treat dyslipidemia, diarrhoea, and hepatitis since ancient times. B. orellana L., seeds contain an orange-red coloured component known as bixin (C25H30O4), which constitutes 80% of the extract.Chemically, bixin is a natural apocarotenoid, biosynthesized through the oxidative degradation of C40 ...
Source: Fitoterapia - July 16, 2023 Category: Biochemistry Authors: Asma Ashraf Muhammad Umar Ijaz Saima Muzammil Muhammad Muzammil Nazir Saima Zafar S M Neamul Kabir Zihad Shaikh Jamal Uddin Md Saquib Hasnain Amit Kumar Nayak Source Type: research

Exploration of the Production of Three Thiodiketopiperazines by an Endophytic Fungal Strain of Cophinforma mamane
In this study, we focused on the production of 3 thiodiketopiperazines (TDKPs) botryosulfuranols A-C produced by an endophytic strain of Cophinforma mamane isolated from the leaves of Bixa orellana L collected in the Peruvian Amazon. We studied the time-course production of botryosulfuranols A-C during 28 days and evaluated the variations in the production of secondary metabolites, including the TDKPs, produced by C. mamane in response to different culture media, light versus dark conditions and different incubation times. We observed a short time-frame production of botryosulfuranol C while its production was significantl...
Source: Chemistry and Biodiversity - March 15, 2023 Category: Biochemistry Authors: Romina Geraldine Pacheco-Tapia Sergio Ortiz Patricia Jargeat Carlos Amasifuen Marieke Vansteelandt Mohamed Haddad Source Type: research