Ethnoveterinary knowledge and practices at Colares island, Pará state, eastern Amazon, Brazil
Conclusion The present study contributed to the establishment of an inventory of plants used in ethnoveterinary practices in this region of the Brazilian eastern Amazon. Future phytochemical and pharmacological studies are needed to confirm the efficacy and safety of the identified plants, enabling communities to use them in a more economic, effective and safe manner. Graphical abstract Highlights (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - October 12, 2014 Category: Drugs & Pharmacology Source Type: research
Bixin Action in the Healing Process of Rats Mouth Wounds.
Abstract
Oral lesions that manifest as ulcer lesions are quite common and can cause discomfort to the patient. Searching for drugs to accelerate the healing of these lesions is nonstop process. Bixin is a molecule found in annatto (urucum) seeds and is considered a viable therapeutic option to treat such lesions due to its anti-inflammatory, anti-oxidant, and healing properties. Therefore, the present study aimed to evaluate the effect of the bixin solution in the ulcer healing process in the oral mucosa of rats. Ulcers were induced with punches of 0.5 cm in the middle of the dorsum of the tongue of 64 Wis...
Source: Current Pharmaceutical Biotechnology - December 26, 2013 Category: Biotechnology Authors: Piva RM, Rodrigues Johann AC, Costa CK, Miguel OG, Rosa ER, de Azevedo-Alanis LR, Trevilatto PC, Ignácio SA, Cassi Bettega PV, Grégio AM Tags: Curr Pharm Biotechnol Source Type: research
Safety and Efficacy of Bixa orellana (Achiote, Annatto) Leaf Extracts
Bixa orellana leaf preparations have been used for many years by indigenous people for a variety of medicinal applications. Published research studies in animals indicate that various extracts of Bixa leaves exhibit antioxidant, broad antimicrobial (antibacterial and antifungal), anti‐inflammatory, analgesic, hypoglycemic, and antidiarrheal activities. No studies have specifically assessed the ability of leaf extracts to inhibit urogenital infections although Bixa products have been used in folkloric medicine to treat gonorrhea and other infections. Few human studies have been conducted and published using Bixa leaf prep...
Source: Phytotherapy Research - December 4, 2013 Category: Biochemistry Authors: Sidney J. Stohs Tags: Review Source Type: research
The Influence of Bleaching Agent and Temperature on Bleaching Efficacy and Volatile Components of Fluid Whey and Whey Retentate
This study determined the impact of temperature and bleaching agent on bleaching efficacy and volatile components in fluid whey and fluid whey retentate. Freshly manufactured liquid whey (6.7% solids) or concentrated whey protein (retentate) (12% solids, 80% protein) were bleached using benzoyl peroxide (BP) at 100 mg/kg (w/w) or hydrogen peroxide (HP) at 250 mg/kg (w/w) at 5 °C for 16 h or 50 °CC for 1 h. Unbleached controls were subjected to a similar temperature profile. The experiment was replicated three times. Annatto destruction (bleaching efficacy) among treatments was compared, and volatile compounds were extrac...
Source: Journal of Food Science - September 16, 2013 Category: Food Science Authors: A.J. Fox, T.J. Smith, P.D. Gerard, M.A. Drake Tags: C: Food Chemistry Source Type: research
Antileishmanial Activity of the Essential Oil from Bixa orellana
Leishmaniasis is a neglected tropical disease caused by Leishmania protozoa. There is currently no vaccine against leishmaniasis, and chemotherapy remains the only effective control. However, conventional drugs are toxic, expensive, and require long periods of treatment, and resistance to clinical chemotherapeutic agents is emerging. Recent research on plants has shown a successful approach to obtain new antileishmanial alternatives. Herein, the in vitro and in vivo effects of the essential oil from Bixa orellana seeds against Leishmania amazonensis were evaluated. A total of 73 compounds were detected by gas chromatograph...
Source: Phytotherapy Research - August 27, 2013 Category: Biochemistry Authors: Lianet Monzote, Marley García, Ramón Scull, Armando Cuellar, William N. Setzer Tags: Research Article Source Type: research
Effect of annatto-tocotrienols supplementation on the development of mammary tumors in HER-2/neu transgenic mice
Tocotrienols (T3), the lesser known isomers of vitamin E, have been reported to possess anticancer activity both in in vitro and in vivo experimental models of rodents transplanted with parental tumors or treated with carcinogens. We investigated the effects of dietary supplementation with annatto-T3 (90% -T3 and 10% -T3) on the spontaneous development of mammary tumors in HER-2/neu transgenic mice. Underlying mechanisms of the antitumor effect were evaluated by studying apoptosis, senescent-like growth arrest, immune modulation, oxidative effect and the expression of HER-2/neu in tumoral mammary glands of transgenic mice ...
Source: Carcinogenesis - June 3, 2013 Category: Cancer & Oncology Authors: Pierpaoli, E., Viola, V., Barucca, A., Orlando, F., Galli, F., Provinciali, M. Tags: Original Manuscript Source Type: research
Effect of bixin and norbixin on the expression of cytochrome P450 in HepG2 cell line.
In this study, the ability of bixin and norbixin to induce the cytochrome P450 (CYP) enzymes was assessed in HepG2 human hepatoma cell line. HepG2 cells were treated with bixin and norbixin, and the expression of the CYP genes quantified by real-time reverse transcription polymerase chain reaction (RT-PCR). Expression of CYP1A1 and CYP1A2 was significantly increased by bixin treatment, while CYP2B6, 2C9, 2E1 and 3A4 were unaffected. Cells were treated with norbixin showed no inducer effect. The results suggest that the inducer potential of annatto is attributed to bixin, but not to norbixin, despite their similarities in m...
Source: Cell Biology International - March 30, 2013 Category: Cytology Authors: Matuo MC, de Oliveira Takamoto RT, Kikuchi IS, de Jesus Andreoli Pinto T Tags: Cell Biol Int Source Type: research
Chemical constituents and antihistamine activity of Bixa orellana leaf extract
Conclusions:
The experimental findings demonstrated that the anti-inflammatory activity of AEBO was due to its inhibitory effect on vascular permeability, which was suppressed as a result of the reduced expression of biochemical mediators (NO and VEGF) in tissues. Our results contribute towards the validation of the traditional use of Bixa orellana in the treatment of inflammatory disorders. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - February 14, 2013 Category: Complementary Medicine Authors: Yoke YongZainul ZakariaArifah KadirMuhammad SomchitGwendoline Ee Cheng LianZuraini Ahmad Source Type: research
The Impact of Iron on the Bleaching Efficacy of Hydrogen Peroxide in Liquid Whey Systems
Abstract
Whey is a value‐added product that is utilized in many food and beverage applications for its nutritional and functional properties. Whey and whey products are generally utilized in dried ingredient applications. One of the primary sources of whey is from colored Cheddar cheese manufacture that contains the pigment annatto resulting in a characteristic yellow colored Cheddar cheese. The colorant is also present in the liquid cheese whey and must be bleached so that it can be used in ingredient applications without imparting a color. Hydrogen peroxide and benzoyl peroxide are 2 commercially approved chemical b...
Source: Journal of Food Science - January 18, 2013 Category: Food Science Authors: Suzanne M. Jervis, MaryAnne Drake Tags: R: Concise Reviews in Food Science Source Type: research
