Effect of the Association of Fixed Oils from < em > Abelmoschus esculentus < /em > (L.) Moench, < em > Euterpe oleracea < /em > Martius, < em > Bixa orellana < /em > Linn é and Chronic SM < sup > ® < /sup > on Atherogenic Dyslipidemia in Wistar Rats

This study investigated the effects of treatments with oils from A. esculentus, E. oleracea, B. orellana, and Chronic SM® on Cocos nucifera L. saturated-fat-induced dyslipidemia. The chromatographic profile showed the majority presence of unsaturated fatty acids in the tested oils. The quantification of tocotrienols and geranylgeraniol in OFBO and CHR was obtained. Treatments with OFEO, OFAE, OFBO, and CHR were able to significantly reduce glycemia, as well as hypertriglyceridemia, total cholesterol, and LDL-cholesterol, besides increasing HDL-cholesterol. The treatments inhibited the formation of atheromatous plaques in the vascular endothelium of the treated rats. The obtained results suggest that the OFEO, OFAE, OFBO, and CHR exhibit antidyslipidemic effects and antiatherogenic activity.PMID:37764465 | PMC:PMC10534590 | DOI:10.3390/molecules28186689

Source: Atherosclerosis - September 28, 2023 Category: Cardiology Authors: Priscila Faimann Sales Aline Lopes do Nascimento Fernanda Cavalcante Pinheiro Andressa Ketelem Meireles Alberto Abrah ão Victor Tavares de Lima Teixeira Dos Santos Helison de Oliveira Carvalho Gisele Cust ódio de Souza Jos é Carlos Tavares Carvalho Source Type: research